PL1828378T3 - Deacylacja lps w bakteriach gram ujemnych - Google Patents

Deacylacja lps w bakteriach gram ujemnych

Info

Publication number
PL1828378T3
PL1828378T3 PL05815467T PL05815467T PL1828378T3 PL 1828378 T3 PL1828378 T3 PL 1828378T3 PL 05815467 T PL05815467 T PL 05815467T PL 05815467 T PL05815467 T PL 05815467T PL 1828378 T3 PL1828378 T3 PL 1828378T3
Authority
PL
Poland
Prior art keywords
deacylation
lps
negative bacteria
gram negative
gram
Prior art date
Application number
PL05815467T
Other languages
English (en)
Polish (pl)
Inventor
Johannes Petrus Maria Tommassen
Der Ley Peter André Van
Jeroen Johannes Gerardus Geurtsen
Original Assignee
De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport filed Critical De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport
Publication of PL1828378T3 publication Critical patent/PL1828378T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL05815467T 2004-12-17 2005-12-16 Deacylacja lps w bakteriach gram ujemnych PL1828378T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04078445 2004-12-17
EP05815467.5A EP1828378B1 (en) 2004-12-17 2005-12-16 Deacylation of lps in gram negative bacteria
PCT/NL2005/050081 WO2006065139A2 (en) 2004-12-17 2005-12-16 Deacylation of lps in gram negative bacteria

Publications (1)

Publication Number Publication Date
PL1828378T3 true PL1828378T3 (pl) 2014-10-31

Family

ID=34928754

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05815467T PL1828378T3 (pl) 2004-12-17 2005-12-16 Deacylacja lps w bakteriach gram ujemnych

Country Status (15)

Country Link
US (1) US8048433B2 (enExample)
EP (1) EP1828378B1 (enExample)
JP (1) JP5378685B2 (enExample)
CN (1) CN101203605B (enExample)
AU (1) AU2005317304B2 (enExample)
BR (1) BRPI0519923A8 (enExample)
CA (1) CA2590906C (enExample)
DK (1) DK1828378T3 (enExample)
ES (1) ES2493440T3 (enExample)
MX (1) MX2007007288A (enExample)
NO (1) NO340331B1 (enExample)
NZ (1) NZ555889A (enExample)
PL (1) PL1828378T3 (enExample)
PT (1) PT1828378E (enExample)
WO (1) WO2006065139A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101667551B1 (ko) * 2007-03-26 2016-10-19 드 슈타트 데르 네덜란덴, 베르테겐부어디그트 두어 드 미니스터 반 베이웨이에스, 미니스테리 반 폭스겐트존하이트, 벨지인 엔 스포츠 Ｌｐｓ 글리코실트랜스퍼레이즈 돌연변이에 기초한 보르데텔라 페르투시스에 대한 개선된 백신
SG11201500573RA (en) 2012-08-06 2015-02-27 Glaxosmithkline Biolog Sa Method for eliciting in infants an immune response against rsv and b. pertussis
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
ES2828373T3 (es) 2013-06-04 2021-05-26 Aparin Petr Gennadievich Lipopolisacárido modificado (variantes) de bacterias endotóxicas, combinación de lipopolisacáridos modificados (variantes) y una vacuna (variantes), que los contiene, y una composición farmacéutica (variantes)
US11052142B2 (en) 2013-06-04 2021-07-06 Petr G. Aparin Modified endotoxic bacteria lipopolysaccharide (variants), combination of modified lipopolysaccharides (variants) and, containing same, a vaccine (variants) and a pharmaceutical composition (variants)
EP3030260A1 (en) 2013-08-05 2016-06-15 GlaxoSmithKline Biologicals S.A. Combination immunogenic compositions
WO2015179270A2 (en) 2014-05-19 2015-11-26 Board Of Regents, The University Of Texas System Combinatorial platform for the display of surface adjuvants and antigens
CN104388368B (zh) * 2014-10-30 2017-02-15 四川农业大学 一株低内毒素大肠杆菌原核表达工程菌突变株及构建方法
BR112018015240A2 (en) * 2016-01-28 2018-12-18 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport lps of modified tetraacylated neisseria
CN105567620B (zh) * 2016-01-29 2019-03-19 江南大学 一株产减毒类脂A的Cronobacter sakazakii突变株及其应用
CN105695540A (zh) * 2016-03-18 2016-06-22 辽宁成大生物股份有限公司 一种革兰氏阴性菌胞壁抗原的制备方法
BR112019018905A2 (pt) 2017-03-13 2020-05-19 De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport vacinas contra bordetella compreendendo lps com reatogenicidade reduzida
WO2018213242A1 (en) * 2017-05-15 2018-11-22 University Of Maryland, Baltimore Live salmonella typhi vectors engineered to express heterologous outer membrane protein antigens and methods of use thereof
US11542467B2 (en) * 2017-12-04 2023-01-03 Intravacc B.V. Process for producing outer membrane vesicles
US20230183656A1 (en) * 2020-05-14 2023-06-15 Merck Patent Gmbh Methods and compositions for purifying adeno associated virus particles or adenoviruses
EP4208472A1 (en) 2020-09-04 2023-07-12 Intravacc B.V. Ompa mutations enhance omv production in bordetella pertussis
EP4169513A1 (en) 2021-10-19 2023-04-26 GlaxoSmithKline Biologicals S.A. Adjuvant composition comprising sting agonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH650681A5 (en) 1981-08-14 1985-08-15 Dso Pharmachim Whooping cough vaccine
JP2918895B2 (ja) * 1987-09-04 1999-07-12 アムジエン・インコーポレーテツド 組換え型ｄｎａ由来ボルデテラ毒素サブユニット類似体
EP0484621A3 (en) * 1990-07-11 1992-08-26 American Cyanamid Company Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens
PL307505A1 (en) * 1992-08-18 1995-05-29 Duphar Int Res Vaccine against bordetella bronchiseptica
ES2180758T3 (es) * 1995-05-04 2003-02-16 Aventis Pasteur Vacunas de pertussis acelulares y metodos de preparacion de las mismas.
US6887483B2 (en) * 1995-12-01 2005-05-03 University Of Iowa Research Foundation Non-toxic mutants of pathogenic gram-negative bacteria
JP5019494B2 (ja) * 1997-04-01 2012-09-05 コリクサ コーポレーション モノホスホリルリピドａの水性免疫アジュバント組成物
CA2264970A1 (en) 1998-03-10 1999-09-10 American Cyanamid Company Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria
AU762369B2 (en) * 1998-11-03 2003-06-26 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur LPS with reduced toxicity from genetically modified gram negative bacteria
US6531131B1 (en) * 1999-08-10 2003-03-11 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for Neisseria meningitidis
US20030113742A1 (en) * 2001-04-20 2003-06-19 University Of Iowa Research Foundation Methods and compositions for the modulation of biofilm formation

Also Published As

Publication number Publication date
MX2007007288A (es) 2008-02-25
WO2006065139A2 (en) 2006-06-22
CA2590906A1 (en) 2006-06-22
EP1828378B1 (en) 2014-06-11
AU2005317304B2 (en) 2011-06-23
PT1828378E (pt) 2014-10-10
JP2008523805A (ja) 2008-07-10
EP1828378A2 (en) 2007-09-05
ES2493440T3 (es) 2014-09-11
NO340331B1 (no) 2017-04-03
US8048433B2 (en) 2011-11-01
CA2590906C (en) 2017-01-03
AU2005317304A1 (en) 2006-06-22
CN101203605B (zh) 2016-01-27
BRPI0519923A2 (pt) 2009-08-11
BRPI0519923A8 (pt) 2018-01-23
DK1828378T3 (da) 2014-09-01
JP5378685B2 (ja) 2013-12-25
NO20073088L (no) 2007-09-17
WO2006065139A3 (en) 2006-10-19
NZ555889A (en) 2009-07-31
US20080274145A1 (en) 2008-11-06
CN101203605A (zh) 2008-06-18

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