JP4638876B2 - Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用 - Google Patents

Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用 Download PDF

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JP4638876B2
JP4638876B2 JP2006533390A JP2006533390A JP4638876B2 JP 4638876 B2 JP4638876 B2 JP 4638876B2 JP 2006533390 A JP2006533390 A JP 2006533390A JP 2006533390 A JP2006533390 A JP 2006533390A JP 4638876 B2 JP4638876 B2 JP 4638876B2
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gitrl
cells
gitr
antibody
cell
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JP2007515942A5 (https=
JP2007515942A (ja
Inventor
コリンズ，メアリー
シーバッチ，イーサン・メナヘム
マッキュー，レベッカ・スザンヌ
ホワイターズ，マシュー・ジェームズ
ヤング，デボラ・アン
バーン，マイケル・チャップマン
レディ，パドマラーサ・エス
スティーブンス，ジェフリー・ローレンス
カレーニョ，ベアトリズ・エム
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Wyeth LLC
Government of the United States of America
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Wyeth LLC
Government of the United States of America
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

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  • General Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Dermatology (AREA)
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  • Biotechnology (AREA)
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JP2006533390A 2003-05-23 2004-05-24 Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用 Expired - Lifetime JP4638876B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47284403P 2003-05-23 2003-05-23
US54797504P 2004-02-26 2004-02-26
PCT/US2004/016381 WO2004107618A2 (en) 2003-05-23 2004-05-24 Gitr ligand and gitr ligand-related molecules and antibodies and uses thereof

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JP2010209408A Division JP2011055833A (ja) 2003-05-23 2010-09-17 Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用

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JP2007515942A JP2007515942A (ja) 2007-06-21
JP2007515942A5 JP2007515942A5 (https=) 2007-08-02
JP4638876B2 true JP4638876B2 (ja) 2011-02-23

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JP2006533390A Expired - Lifetime JP4638876B2 (ja) 2003-05-23 2004-05-24 Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用
JP2010209408A Pending JP2011055833A (ja) 2003-05-23 2010-09-17 Ｇｉｔｒリガンド及びｇｉｔｒリガンド関連分子及び抗体及びその使用

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US (2) US7618632B2 (https=)
EP (1) EP1631588A2 (https=)
JP (2) JP4638876B2 (https=)
KR (1) KR20060052681A (https=)
AU (1) AU2004244626A1 (https=)
BR (1) BRPI0410785A (https=)
CA (1) CA2525717A1 (https=)
CO (1) CO5680484A2 (https=)
MX (1) MXPA05012475A (https=)
NO (1) NO20055306L (https=)
NZ (1) NZ543654A (https=)
RU (1) RU2369636C2 (https=)
WO (1) WO2004107618A2 (https=)

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MXPA05012475A (es) 2006-05-25
CA2525717A1 (en) 2004-12-09
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WO2004107618A2 (en) 2004-12-09
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CO5680484A2 (es) 2006-09-29
US20050014224A1 (en) 2005-01-20
US7618632B2 (en) 2009-11-17
BRPI0410785A (pt) 2006-06-20
JP2007515942A (ja) 2007-06-21
JP2011055833A (ja) 2011-03-24
NO20055306D0 (no) 2005-11-10
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WO2004107618A3 (en) 2005-02-10
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