DK0979226T3 - Isoxazolderivater - Google Patents

Isoxazolderivater

Info

Publication number
DK0979226T3
DK0979226T3 DK98914071T DK98914071T DK0979226T3 DK 0979226 T3 DK0979226 T3 DK 0979226T3 DK 98914071 T DK98914071 T DK 98914071T DK 98914071 T DK98914071 T DK 98914071T DK 0979226 T3 DK0979226 T3 DK 0979226T3
Authority
DK
Denmark
Prior art keywords
group
formula
represented
solid line
single bond
Prior art date
Application number
DK98914071T
Other languages
English (en)
Inventor
Masashi Nakatsuka
Yoshihide Ueno
Shin-Ichiro Okada
Fumio Nishikaku
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Application granted granted Critical
Publication of DK0979226T3 publication Critical patent/DK0979226T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DK98914071T 1997-04-21 1998-04-17 Isoxazolderivater DK0979226T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11887197 1997-04-21
JP36715497 1997-12-24

Publications (1)

Publication Number Publication Date
DK0979226T3 true DK0979226T3 (da) 2006-03-06

Family

ID=26456721

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98914071T DK0979226T3 (da) 1997-04-21 1998-04-17 Isoxazolderivater

Country Status (14)

Country Link
EP (1) EP0979226B1 (da)
KR (1) KR100512087B1 (da)
CN (1) CN1138764C (da)
AT (1) ATE309228T1 (da)
AU (1) AU733091B2 (da)
CA (1) CA2235298C (da)
DE (1) DE69832270T2 (da)
DK (1) DK0979226T3 (da)
ES (1) ES2248894T3 (da)
ID (1) ID22897A (da)
NZ (1) NZ330244A (da)
RU (1) RU2196770C2 (da)
TW (1) TW442476B (da)
WO (1) WO1998047880A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2377527A1 (en) * 1999-07-15 2001-01-25 Sumitomo Pharmaceuticals Co., Ltd. Heteroaromatic ring compounds
WO2001047895A1 (fr) * 1999-12-28 2001-07-05 Sumitomo Pharmaceuticals Company, Limited Nouveaux composes comprenant des cycles heteroaromatiques a cinq chainons
CA2441798C (en) * 2001-03-27 2009-10-20 Sumitomo Pharmaceuticals Company, Limited Crystalline isoxazole derivative and medical preparation thereof
JPWO2003068239A1 (ja) * 2002-02-12 2005-06-02 住友製薬株式会社 新規外用剤
ITMI20040019A1 (it) * 2004-01-12 2004-04-12 Univ Bari Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
DE102004008141A1 (de) 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
CA2589808A1 (en) * 2004-11-02 2006-05-11 Dainippon Sumitomo Pharma Co., Ltd. Combination drug for treating autoimmune disease
US7989450B2 (en) 2008-01-11 2011-08-02 Universita' Degli Studi Di Bari Functionalized diarylisoxazoles inhibitors of ciclooxygenase
PL2668182T3 (pl) * 2011-01-28 2018-11-30 Immunic Ag Inhibitowanie IL17 i IFN-gamma do leczenia zapalenia autoimmunologicznego
DE102014201651A1 (de) 2014-01-30 2015-07-30 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Isoxazolderivate zur Verwendung bei der Behandlung und/oder Prophylaxe von Herzerkrankungen
CN111269149B (zh) * 2020-04-08 2022-04-15 南京优氟医药科技有限公司 一种5-(3,3-二甲基胍基)-2-氧代戊酸的生产工艺
CN114478350B (zh) * 2022-01-25 2023-08-11 苏州大学 一种c3-烷基化吲哚的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2068418A1 (en) * 1969-10-27 1971-08-27 Innothera Lab Sa 2-substd-5-amino isoxazole derivs
US3720685A (en) * 1970-07-15 1973-03-13 Squibb & Sons Inc 3-amino-5-benzyl-1,2,4-oxadiazoles
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
DE2341507A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zur herstellung
JPS54144347A (en) * 1978-05-02 1979-11-10 Nikken Kagaku Kk 3-(2-fluoro-4-biphenylyl)-2-butanone
HU180567B (en) * 1980-03-19 1983-03-28 Egyt Gyogyszervegyeszeti Gyar Method for producing derivatives of isooxazole
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な1,2,4−オキサジアゾ−ル誘導体
US4680300A (en) * 1985-01-10 1987-07-14 Syntex (U.S.A.) Inc. Anti-inflammatory guanidines
US4914112A (en) * 1986-06-03 1990-04-03 Sumitomo Pharmaceuticals Company, Limited Aminoazole derivatives and their production and use
JP2719742B2 (ja) * 1991-04-30 1998-02-25 株式会社大塚製薬工場 フェニルチアゾール誘導体

Also Published As

Publication number Publication date
DE69832270D1 (de) 2005-12-15
AU6193498A (en) 1998-10-22
CA2235298C (en) 2008-05-13
CA2235298A1 (en) 1998-10-21
DE69832270T2 (de) 2006-07-13
NZ330244A (en) 2000-01-28
ES2248894T3 (es) 2006-03-16
AU733091B2 (en) 2001-05-03
WO1998047880A1 (en) 1998-10-29
CN1252794A (zh) 2000-05-10
KR100512087B1 (ko) 2005-09-05
KR20010006501A (ko) 2001-01-26
ID22897A (id) 1999-12-16
ATE309228T1 (de) 2005-11-15
EP0979226B1 (en) 2005-11-09
CN1138764C (zh) 2004-02-18
EP0979226A1 (en) 2000-02-16
TW442476B (en) 2001-06-23
RU2196770C2 (ru) 2003-01-20

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