JP4009318B2 - エンドトキセミアの治療及び防止に有用な置換されたリポ糖類 - Google Patents
エンドトキセミアの治療及び防止に有用な置換されたリポ糖類 Download PDFInfo
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- JP4009318B2 JP4009318B2 JP50186897A JP50186897A JP4009318B2 JP 4009318 B2 JP4009318 B2 JP 4009318B2 JP 50186897 A JP50186897 A JP 50186897A JP 50186897 A JP50186897 A JP 50186897A JP 4009318 B2 JP4009318 B2 JP 4009318B2
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| JP3943334B2 (ja) * | 1998-09-01 | 2007-07-11 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リピッドａ類縁体含有注射剤の評価方法 |
| US20030130212A1 (en) * | 1999-01-14 | 2003-07-10 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by intravenous infusion |
| ATE375798T1 (de) | 1999-01-14 | 2007-11-15 | Eisai R&D Man Co Ltd | Verwendung von e5564 zur behandlung von sepsis durch intravenöse infusion |
| US6835721B2 (en) | 1999-02-01 | 2004-12-28 | Eisai Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| US7915238B2 (en) * | 1999-02-01 | 2011-03-29 | Eisai R & D Management Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| TR200102325T2 (tr) * | 1999-02-10 | 2002-08-21 | Sankyo Company Limited | Eter tipi lipid A 1-karbosiklik asit analogları |
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| US20050101549A1 (en) * | 2000-01-14 | 2005-05-12 | Melvyn Lynn | Prevention and treatment of endotoxemia and related complications associated with surgery |
| EP2452684B1 (en) | 2000-02-18 | 2018-01-24 | Eisai R&D Management Co., Ltd. | Micelles |
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| US20030105033A1 (en) * | 2000-06-09 | 2003-06-05 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion |
| US20020042379A1 (en) * | 2000-06-09 | 2002-04-11 | Daniel Rossignol | Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion |
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| US20040198652A1 (en) * | 2001-04-24 | 2004-10-07 | Carter J. Paul | Methods and compositions for preventing and treating septic shock and endotoxemia |
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| DE10125179A1 (de) * | 2001-05-23 | 2002-12-05 | Laves Ralph Georg | Verwendung von LPS zur Behandlung intestinaler Entzündungsprozesse |
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| US20040254128A1 (en) * | 2001-08-10 | 2004-12-16 | Seiichi Kobayashi | Treatment and prevention of heat shock protein-associated diseases and conditions |
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| AU2002950657A0 (en) * | 2002-08-08 | 2002-09-12 | Alchemia Limited | Derivatives of monosaccharides for drug discovery |
| AU2002951995A0 (en) * | 2002-10-11 | 2002-10-31 | Alchemia Limited | Classes of compounds that interact with gpcrs |
| AU2003289493A1 (en) * | 2002-12-24 | 2004-07-22 | Mochizuki, Takashi | Lipid a analogues having glucose as the right sugar |
| CN101863930A (zh) * | 2003-01-06 | 2010-10-20 | 科里克萨有限公司 | 一些氨烷基氨基葡糖苷磷酸酯化合物和它们的用途 |
| MXPA05008080A (es) * | 2003-01-28 | 2006-02-08 | Octoplus Technologies B V | Inhibidores peptidicos de toxinas derivadas de la ll-37. |
| JP4773336B2 (ja) * | 2003-02-20 | 2011-09-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法 |
| EP1601661A2 (en) * | 2003-03-05 | 2005-12-07 | Eisai Co., Ltd | Compositions and methods for preventing and treating endotoxin-related diseases and conditions |
| WO2005027826A2 (en) * | 2003-07-14 | 2005-03-31 | Eisai, Co, Ltd. | Methods and treating severe acute respiratory syndrome |
| WO2005072097A2 (en) | 2003-12-16 | 2005-08-11 | University Of Massachusetts | Toll-like receptor 9 modulators |
| KR20060121293A (ko) * | 2004-01-08 | 2006-11-28 | 상꾜 가부시키가이샤 | 좌당 글루코오스리피드ａ 유연체 |
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| US20100015125A1 (en) * | 2005-06-17 | 2010-01-21 | University Of Rochester | Methods and compositions for enhancing immune memory by blocking intrahepatic activated t cell deletion |
| JP5118968B2 (ja) * | 2005-08-31 | 2013-01-16 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リピッドａ類縁体の製造方法 |
| EP1939209A4 (en) * | 2005-08-31 | 2010-07-07 | Eisai R&D Man Co Ltd | PROCESS FOR PREPARING A LIPID A ANALOGON |
| US7943588B2 (en) | 2006-03-28 | 2011-05-17 | Trustees Of Dartmouth College | Method for preventing or treating neuropathic pain |
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