JP4009318B2 - エンドトキセミアの治療及び防止に有用な置換されたリポ糖類 - Google Patents
エンドトキセミアの治療及び防止に有用な置換されたリポ糖類 Download PDFInfo
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- JP4009318B2 JP4009318B2 JP50186897A JP50186897A JP4009318B2 JP 4009318 B2 JP4009318 B2 JP 4009318B2 JP 50186897 A JP50186897 A JP 50186897A JP 50186897 A JP50186897 A JP 50186897A JP 4009318 B2 JP4009318 B2 JP 4009318B2
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| US20030130212A1 (en) * | 1999-01-14 | 2003-07-10 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by intravenous infusion |
| US6835721B2 (en) | 1999-02-01 | 2004-12-28 | Eisai Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| US7915238B2 (en) * | 1999-02-01 | 2011-03-29 | Eisai R & D Management Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
| US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
| TW527358B (en) * | 1999-02-10 | 2003-04-11 | Sankyo Co | Ether type lipid A1 position carboxylic acid analogue |
| JP2003524638A (ja) * | 2000-01-14 | 2003-08-19 | エーザイ株式会社 | 手術に伴う内毒素血症及び関連する合併症の予防及び治療 |
| US20050101549A1 (en) * | 2000-01-14 | 2005-05-12 | Melvyn Lynn | Prevention and treatment of endotoxemia and related complications associated with surgery |
| AU2001238507C9 (en) * | 2000-02-18 | 2005-07-07 | Eisai R&D Management Co., Ltd. | Micelles |
| US6861512B2 (en) * | 2000-03-01 | 2005-03-01 | Eisai Co., Ltd. | Separation of olefinic isomers |
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| US20030105033A1 (en) * | 2000-06-09 | 2003-06-05 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion |
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| JPWO2002088072A1 (ja) * | 2001-04-23 | 2004-08-12 | エーザイ株式会社 | アルキレン化合物の製造方法 |
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| DE10125179A1 (de) * | 2001-05-23 | 2002-12-05 | Laves Ralph Georg | Verwendung von LPS zur Behandlung intestinaler Entzündungsprozesse |
| WO2003013440A2 (en) | 2001-08-10 | 2003-02-20 | Eisai Co., Ltd. | Treatment and prevention of heat shock protein-associated diseases and conditions |
| US7727974B2 (en) * | 2001-08-10 | 2010-06-01 | Eisai R & D Management Co., Ltd. | Methods of reducing the severity of mucositis |
| WO2003050137A2 (en) * | 2001-12-11 | 2003-06-19 | David Schwartz | Toll-like receptor 4 mutations |
| AU2002950657A0 (en) * | 2002-08-08 | 2002-09-12 | Alchemia Limited | Derivatives of monosaccharides for drug discovery |
| AU2002951995A0 (en) * | 2002-10-11 | 2002-10-31 | Alchemia Limited | Classes of compounds that interact with gpcrs |
| WO2004058788A1 (ja) * | 2002-12-24 | 2004-07-15 | Sankyo Company, Limited | 右糖グルコースリピドa類縁体 |
| MXPA05007295A (es) * | 2003-01-06 | 2005-09-30 | Corixa Corp | Ciertos compuestos de fosfato de aminoalquil glucosaminida y su uso. |
| DE602004021901D1 (de) * | 2003-01-28 | 2009-08-20 | Academisch Ziekenhuis Leiden | Aus ll-37 abgeleiteten peptidinhibitoren von toxinen |
| JP4773336B2 (ja) * | 2003-02-20 | 2011-09-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Ｌｐｓアンタゴニストｂ１２８７およびその立体異性体の調製のための試薬および方法 |
| BRPI0408077A (pt) * | 2003-03-05 | 2006-02-14 | Eisai Co Ltd | composições e métodos para prevenção e tratamento de doenças relacionadas com endotoxina e condições |
| WO2005027826A2 (en) * | 2003-07-14 | 2005-03-31 | Eisai, Co, Ltd. | Methods and treating severe acute respiratory syndrome |
| WO2005059517A2 (en) | 2003-12-16 | 2005-06-30 | University Of Massachusetts | Toll-like receptor assays |
| EP1702926A4 (en) * | 2004-01-08 | 2010-03-17 | Sankyo Co | LEVULOSEGLUCOSELIPID-A-ANALOG |
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| JP5185813B2 (ja) | 2005-04-26 | 2013-04-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 癌免疫治療のための組成物および方法 |
| WO2006138681A2 (en) * | 2005-06-17 | 2006-12-28 | University Of Rochester | Methods and compositions for enhancing immune memory by blocking intrahepatic activated t cell deletion |
| JP5118968B2 (ja) * | 2005-08-31 | 2013-01-16 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リピッドａ類縁体の製造方法 |
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| DD295854A5 (de) | 1989-12-11 | 1991-11-14 | ��@���������@�������k�� | Lipid-a-austauschstoffe mit immunoaktivierender und antitumorwirkung |
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