JP3241720B2 - 封入すべき外来物質に対する取り込み容量が増加されたリポソームの製造方法 - Google Patents

封入すべき外来物質に対する取り込み容量が増加されたリポソームの製造方法

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Publication number
JP3241720B2
JP3241720B2 JP50206292A JP50206292A JP3241720B2 JP 3241720 B2 JP3241720 B2 JP 3241720B2 JP 50206292 A JP50206292 A JP 50206292A JP 50206292 A JP50206292 A JP 50206292A JP 3241720 B2 JP3241720 B2 JP 3241720B2
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JP
Japan
Prior art keywords
liposome
liposomes
lipid
encapsulated
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP50206292A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05504150A (ja
Inventor
シュナイダー，ミシェル
トゥールニエ，エルベ
ヤサントゥ，ローラン
ギロ，クリスチャン
ラミ，ベルナール
Original Assignee
ブラッコ インターナショナル ベスローテン フェンノートシャップ
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Application filed by ブラッコ インターナショナル ベスローテン フェンノートシャップ filed Critical ブラッコ インターナショナル ベスローテン フェンノートシャップ
Publication of JPH05504150A publication Critical patent/JPH05504150A/ja
Application granted granted Critical
Publication of JP3241720B2 publication Critical patent/JP3241720B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP50206292A 1990-12-11 1991-12-09 封入すべき外来物質に対する取り込み容量が増加されたリポソームの製造方法 Expired - Fee Related JP3241720B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90810969 1990-12-11
EP90810969.7 1990-12-11

Publications (2)

Publication Number Publication Date
JPH05504150A JPH05504150A (ja) 1993-07-01
JP3241720B2 true JP3241720B2 (ja) 2001-12-25

Family

ID=8205973

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50206292A Expired - Fee Related JP3241720B2 (ja) 1990-12-11 1991-12-09 封入すべき外来物質に対する取り込み容量が増加されたリポソームの製造方法

Country Status (20)

Country Link
US (1) US5393530A (cg-RX-API-DMAC7.html)
EP (1) EP0514523B1 (cg-RX-API-DMAC7.html)
JP (1) JP3241720B2 (cg-RX-API-DMAC7.html)
KR (1) KR0137783B1 (cg-RX-API-DMAC7.html)
AT (1) ATE131724T1 (cg-RX-API-DMAC7.html)
AU (1) AU635456B2 (cg-RX-API-DMAC7.html)
CA (1) CA2072559C (cg-RX-API-DMAC7.html)
DE (1) DE69115682T2 (cg-RX-API-DMAC7.html)
DK (1) DK0514523T3 (cg-RX-API-DMAC7.html)
ES (1) ES2081605T3 (cg-RX-API-DMAC7.html)
GR (1) GR3018506T3 (cg-RX-API-DMAC7.html)
HU (1) HUT62458A (cg-RX-API-DMAC7.html)
IE (1) IE72163B1 (cg-RX-API-DMAC7.html)
IL (1) IL99835A (cg-RX-API-DMAC7.html)
IN (1) IN172269B (cg-RX-API-DMAC7.html)
IS (1) IS1685B (cg-RX-API-DMAC7.html)
MX (1) MX9102516A (cg-RX-API-DMAC7.html)
NZ (1) NZ240817A (cg-RX-API-DMAC7.html)
WO (1) WO1992010166A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA918489B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
IS1685B (is) 1998-02-24
ATE131724T1 (de) 1996-01-15
DK0514523T3 (da) 1996-01-29
IE914289A1 (en) 1992-06-17
ES2081605T3 (es) 1996-03-16
ZA918489B (en) 1992-07-29
CA2072559A1 (en) 1992-06-12
KR0137783B1 (ko) 1998-05-15
HUT62458A (en) 1993-05-28
JPH05504150A (ja) 1993-07-01
WO1992010166A1 (en) 1992-06-25
CA2072559C (en) 1997-03-18
IE72163B1 (en) 1997-03-26
MX9102516A (es) 1992-06-01
EP0514523B1 (en) 1995-12-20
NZ240817A (en) 1993-01-27
IS3773A7 (is) 1992-06-12
IN172269B (cg-RX-API-DMAC7.html) 1993-05-29
IL99835A (en) 1995-11-27
IL99835A0 (en) 1992-08-18
KR920703014A (ko) 1992-12-17
AU9062991A (en) 1992-07-08
DE69115682T2 (de) 1996-05-15
EP0514523A1 (en) 1992-11-25
DE69115682D1 (de) 1996-02-01
GR3018506T3 (en) 1996-03-31
AU635456B2 (en) 1993-03-18
US5393530A (en) 1995-02-28

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