MX9102516A - Metodo para fabricar liposomas de una capacidad de atrape mejorada hacia las substancias extrañas que se van a encapsular. - Google Patents

Metodo para fabricar liposomas de una capacidad de atrape mejorada hacia las substancias extrañas que se van a encapsular.

Info

Publication number
MX9102516A
MX9102516A MX9102516A MX9102516A MX9102516A MX 9102516 A MX9102516 A MX 9102516A MX 9102516 A MX9102516 A MX 9102516A MX 9102516 A MX9102516 A MX 9102516A MX 9102516 A MX9102516 A MX 9102516A
Authority
MX
Mexico
Prior art keywords
pct
encapsulated
substances
date jun
manufacturing liposomes
Prior art date
Application number
MX9102516A
Other languages
English (en)
Inventor
Michel Schneider
Herve Tournier
Roland Hyacinthe
Christian Guillot
Bernard Lamy
Original Assignee
Sint Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sint Sa filed Critical Sint Sa
Publication of MX9102516A publication Critical patent/MX9102516A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX9102516A 1990-12-11 1991-12-11 Metodo para fabricar liposomas de una capacidad de atrape mejorada hacia las substancias extrañas que se van a encapsular. MX9102516A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90810969 1990-12-11

Publications (1)

Publication Number Publication Date
MX9102516A true MX9102516A (es) 1992-06-01

Family

ID=8205973

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9102516A MX9102516A (es) 1990-12-11 1991-12-11 Metodo para fabricar liposomas de una capacidad de atrape mejorada hacia las substancias extrañas que se van a encapsular.

Country Status (20)

Country Link
US (1) US5393530A (es)
EP (1) EP0514523B1 (es)
JP (1) JP3241720B2 (es)
KR (1) KR0137783B1 (es)
AT (1) ATE131724T1 (es)
AU (1) AU635456B2 (es)
CA (1) CA2072559C (es)
DE (1) DE69115682T2 (es)
DK (1) DK0514523T3 (es)
ES (1) ES2081605T3 (es)
GR (1) GR3018506T3 (es)
HU (1) HUT62458A (es)
IE (1) IE72163B1 (es)
IL (1) IL99835A (es)
IN (1) IN172269B (es)
IS (1) IS1685B (es)
MX (1) MX9102516A (es)
NZ (1) NZ240817A (es)
WO (1) WO1992010166A1 (es)
ZA (1) ZA918489B (es)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5542935A (en) * 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5352435A (en) * 1989-12-22 1994-10-04 Unger Evan C Ionophore containing liposomes for ultrasound imaging
US5874062A (en) 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
AU5174193A (en) * 1992-10-16 1994-05-09 Georg Rossling Process and device for producing liquid, dispersed systems
US5869305A (en) * 1992-12-04 1999-02-09 The University Of Pittsburgh Recombinant viral vector system
US6217849B1 (en) 1993-09-29 2001-04-17 Bracco Research S.A. Liposome suspensions as blood pool imaging contrast agents
CA2185810A1 (en) * 1994-03-28 1995-10-05 Jo Klaveness Liposomes
CA2187427A1 (en) * 1995-02-24 1996-08-29 Herve Tournier Liposome suspensions as blood pool imaging contrast agents
US5738868A (en) * 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor
US6447800B2 (en) 1996-01-18 2002-09-10 The University Of British Columbia Method of loading preformed liposomes using ethanol
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US20010051131A1 (en) * 1996-06-19 2001-12-13 Evan C. Unger Methods for delivering bioactive agents
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
GB9624918D0 (en) * 1996-11-29 1997-01-15 Nycomed Imaging As Particulate components
WO1998044910A1 (en) 1997-04-09 1998-10-15 Philipp Lang NEW TECHNIQUE TO MONITOR DRUG DELIVERY NONINVASIVELY $i(IN VIVO)
DE19731591C2 (de) * 1997-07-17 1999-09-16 Schering Ag Pharmazeutische Mittel enthaltend perfluoralkylgruppenhaltige Trijodaromaten und ihre Verwendung in der Tumortherapie und interventionellen Radiologie
US6106858A (en) * 1997-09-08 2000-08-22 Skyepharma, Inc. Modulation of drug loading in multivescular liposomes
US6306432B1 (en) * 1997-09-08 2001-10-23 Chiron Corporation High and low load formulations of IGF-I in multivesicular liposomes
NZ503513A (en) * 1997-09-18 2004-12-24 Skyepharma Inc Sustained-release liposomal anesthetic compositions
IL135989A0 (en) 1997-11-14 2001-05-20 Skyepharma Inc Processes for the production of multivesicular liposomes
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19813773A1 (de) * 1998-03-27 1999-09-30 Clemens Unger Verfahren zur Herstellung von liposomalen Wirkstoffformulierungen
EP1098610B1 (en) 1998-07-17 2009-04-15 Pacira Pharmaceuticals, Inc. Biodegradable compositions for the controlled release of encapsulated substances
US6511676B1 (en) 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
EP2286843A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
DE10121903A1 (de) * 2001-04-27 2002-10-31 Nimbus Biotechnologie Gmbh System für die Membranpermeationsmessung
IL158819A0 (en) * 2001-05-31 2004-05-12 Skyepharma Inc Encapsulation of nanosuspensions in liposomes and microspheres
KR100521526B1 (ko) * 2001-07-10 2005-10-13 캐논 가부시끼가이샤 폴리하이드록시알카노에이트로 이루어진 입상 구조체 및그 제조방법
JP3990880B2 (ja) * 2001-07-10 2007-10-17 キヤノン株式会社 ポリヒドロキシアルカノエート被覆リポソームの製造方法
ATE373466T1 (de) * 2001-11-13 2007-10-15 Celator Pharmaceuticals Inc Lipidträgerzusammensetzungen und verfahren zur verbesserten wirkstoffzurückhaltung
EP1443900B1 (en) * 2001-11-13 2012-05-23 Celator Pharmaceuticals, Inc. Lipid carrier compositions with enhanced blood stability
US20030129224A1 (en) * 2001-11-13 2003-07-10 Paul Tardi Lipid carrier compositions and methods for improved drug retention
US20050129750A1 (en) * 2003-12-15 2005-06-16 Yu-Fang Hu Process for producing liposome suspension and product containing liposome suspension produced thereby
EP1547580A1 (en) * 2003-12-23 2005-06-29 MediGene Oncology GmbH Loading of a camptothecin drug into colloidal nanoparticles
EP1547582A1 (en) * 2003-12-23 2005-06-29 MediGene Oncology GmbH Method of producing lipid complexed camptothecin-carboxylate
CN1960707B (zh) 2004-06-03 2012-11-14 博莱科瑞士股份有限公司 用于治疗和/或诊断用途的脂质集合体
EP1809246B1 (en) * 2004-10-08 2008-07-16 Alza Corporation Method of insertion of a lipid-linked moiety into a pre-formed lipid assembly using microwaves
EP1848404A2 (en) * 2005-01-26 2007-10-31 Celator Pharmaceuticals, Inc. Lipid carrier compositions with reduced polydispersity
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
ES2275443B1 (es) * 2005-11-30 2008-06-01 Italfarmaco, S.A. Procedimiento de preparacion de liposomas.
JP5080779B2 (ja) * 2006-10-25 2012-11-21 テルモ株式会社 リポソーム製剤の製造方法
WO2008141230A1 (en) * 2007-05-09 2008-11-20 Lawrence Livermore National Security, Llc Methods and systems for monitoring production of a target protein in a nanolipoprotein particle
US9040079B2 (en) * 2007-11-19 2015-05-26 Biolitec Pharma Marketing Ltd Pegylated compounds for age-related macular degeneration
US9688718B2 (en) 2008-01-11 2017-06-27 Lawrence Livermore National Security, Llc Nanolipoprotein particles comprising hydrogenases and related products, methods and systems
US9303273B2 (en) 2008-05-09 2016-04-05 Lawrence Livermore National Security, Llc Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems
WO2009143280A2 (en) * 2008-05-22 2009-11-26 Lawrence Livermore National Security, Llc Nanolipoprotein particles and related compositions, methods and systems
US9445975B2 (en) * 2008-10-03 2016-09-20 Access Business Group International, Llc Composition and method for preparing stable unilamellar liposomal suspension
EP2346532B1 (en) 2008-10-07 2020-10-07 Bracco Suisse SA Targeting construct comprising anti-polymer antibody and microvesicles binding to the same
EP2184054A1 (en) * 2008-11-08 2010-05-12 Lipoxen Technologies Limited Small Interfering RNA Delivery
CA2781529C (en) 2009-09-23 2017-10-24 Indu Javeri Methods for the preparation of liposomes comprising docetaxel
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
BR112013017939B1 (pt) 2011-01-13 2022-11-16 Variation Biotechnologies Inc Composição imunogênica liofilizada termoestável, uso e método para preparação da mesma
US9644038B2 (en) 2011-12-21 2017-05-09 The Regents Of The University Of California Apolipoprotein nanodiscs with telodendrimer
WO2013104995A2 (en) 2012-01-12 2013-07-18 Variation Biotechnologies, Inc. Compositions and methods for treating viral infections
CA2894467A1 (en) * 2012-01-27 2013-08-01 Variation Biotechnologies Inc. Methods for preparing thermostable compositions comprising a lipid component and thermolabile therapeutic agents
WO2015068020A2 (en) * 2013-11-05 2015-05-14 García-Sánchez Gustavo A Immunosuppressive treatments, formulations and methods
EP3138558B1 (en) * 2014-04-30 2023-06-07 FUJIFILM Corporation Liposome composition and production method therefor
EP3138555B1 (en) 2014-04-30 2020-10-28 FUJIFILM Corporation Liposome composition and production method therefor
WO2016049061A1 (en) 2014-09-22 2016-03-31 Lawrence Livermore National Security, Llc Electrochemical flow-cell for hydrogen production and nicotinamide co-factor dependent target reduction, and related methods and systems
EA201791437A1 (ru) 2014-12-31 2017-12-29 Лантеус Медикал Имэджинг, Инк. Композиции микросфер c инкапсулированным в липиде газом и соответствующие способы
CN107750156B (zh) 2015-05-04 2020-08-21 沃桑缇斯股份公司 用于制备跨膜pH梯度囊泡的方法
US11279749B2 (en) 2015-09-11 2022-03-22 Lawrence Livermore National Security, Llc Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation
EP3372223B1 (en) * 2015-11-02 2024-04-17 FUJIFILM Corporation Liposome composition and method for producing same
CN115531560B (zh) 2016-05-04 2024-05-17 蓝瑟斯医学影像公司 用于制备超声波造影剂的方法及装置
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
US11207422B2 (en) 2017-05-02 2021-12-28 Lawrence Livermore National Security, Llc MOMP telonanoparticles, and related compositions, methods and systems
BR112021026480A2 (pt) * 2019-06-28 2022-02-08 Univ Texas Método para reconstituir anamicina, método para preparar uma dose eficaz de uma formulação lipossômica reconstituída de anamicina e método para tratar câncer
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
CA1270198A (en) * 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
JPS63211222A (ja) * 1987-02-27 1988-09-02 Terumo Corp リポソ−ムの製法
US4963297A (en) * 1987-12-22 1990-10-16 The Liposome Company, Inc. Spontaneous vesticulation of multilamellar liposomes
CH672733A5 (es) * 1987-05-22 1989-12-29 Bracco Ind Chimica Spa
US4870160A (en) * 1987-08-19 1989-09-26 Regents Of The University Of Minnesota Polypeptides with laminin activity
IE63518B1 (en) * 1987-11-18 1995-05-03 Vestar Inc Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
JPH03501732A (ja) * 1987-12-22 1991-04-18 ザ　リポソーム　カンパニー，インコーポレイテッド 多重ラメラリポソームの自発的小胞化方法
DE68916956T2 (de) * 1988-05-20 1994-11-24 Liposome Co Inc Aktives mittel: lipid-komplex mit hohem verhältnis.
IL91664A (en) * 1988-09-28 1993-05-13 Yissum Res Dev Co Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release

Also Published As

Publication number Publication date
IE914289A1 (en) 1992-06-17
CA2072559C (en) 1997-03-18
IS3773A7 (is) 1992-06-12
CA2072559A1 (en) 1992-06-12
JPH05504150A (ja) 1993-07-01
NZ240817A (en) 1993-01-27
ZA918489B (en) 1992-07-29
IN172269B (es) 1993-05-29
AU635456B2 (en) 1993-03-18
WO1992010166A1 (en) 1992-06-25
ES2081605T3 (es) 1996-03-16
GR3018506T3 (en) 1996-03-31
DE69115682D1 (de) 1996-02-01
ATE131724T1 (de) 1996-01-15
EP0514523A1 (en) 1992-11-25
IE72163B1 (en) 1997-03-26
JP3241720B2 (ja) 2001-12-25
IS1685B (is) 1998-02-24
KR920703014A (ko) 1992-12-17
DK0514523T3 (da) 1996-01-29
HUT62458A (en) 1993-05-28
KR0137783B1 (ko) 1998-05-15
US5393530A (en) 1995-02-28
IL99835A0 (en) 1992-08-18
AU9062991A (en) 1992-07-08
IL99835A (en) 1995-11-27
DE69115682T2 (de) 1996-05-15
EP0514523B1 (en) 1995-12-20

Similar Documents

Publication Publication Date Title
MX9102516A (es) Metodo para fabricar liposomas de una capacidad de atrape mejorada hacia las substancias extrañas que se van a encapsular.
DE3482161D1 (de) Zubereitung von arzneimittelhaltigen lipidvesikeln und verfahren zu deren herstellung.
ES2118677T1 (es) Una composicion que comprende un agente activo disuelto en un vehiculo vitrificante y un procedimiento para su preparacion.
MX11339A (es) Una suspension acuosa estable con caracteristicas de liberacion retardada de carbamacepina y procedimiento para su preparacion
ATE71289T1 (de) Paucilamellare lipidvesikel.
ES2054048T3 (es) Vector de particulas util en particular para el transporte de moleculas con actividades biologicas y procedimiento para su preparacion.
PL339768A1 (en) Method of encapsulating aromatic and taste giving substances by controllable delivery of water into microcapsules
EP0171710A3 (en) Process for preparing liposome composition
ES2039759T5 (es) Preparados estables, dispersables en agua fria.
ES2132352T3 (es) Un reactivo para medir leucocitos inmaduros.
DK0797609T3 (da) Polyestere
AP9400683A0 (en) Vaccines.
EP0474790A4 (en) Media for cell growth and method for making them
DE3476338D1 (en) Preparation of unilamellar large diameter liposomes, their pharmaceutical application in view of the encapsulation of the active principle for sustained release, and device therefor
ATE150735T1 (de) Lagerstabil verkapseltes natriumpercarbonat und verfahren zu seiner herstellung
DE69305080D1 (de) Alginatfasern mit verzögerter wirkstofffreigabe und verfahren zu deren herstellung
CA2066761A1 (en) Cell Separation Invention
ES2117267T3 (es) Metodo para encapsular sustancias en biocapsulas.
ES2016824B3 (es) Poliuretanos preparados a partir de polioles que contienen cristales liquidos y proceso para la preparacion de los mismos.
ES2058582T3 (es) Crema dermatologica auto-emulsionable.
Witt Preparation of InP by solution and melt growth techniques
KR880013552A (ko) 디클로페낙 소디움의 마이크로 캡슐화 방법
IT8420303A0 (it) Prodotto antimicotico con elevata cessione di sostanza attiva sottoforma di crema.
Louis For My Lakota Woman
Cookson et al. Convenient synthesis of allenyl sulphides; application to the synthesis of αβ-unsaturated ketones

Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees