ES2118677T1 - Una composicion que comprende un agente activo disuelto en un vehiculo vitrificante y un procedimiento para su preparacion. - Google Patents

Una composicion que comprende un agente activo disuelto en un vehiculo vitrificante y un procedimiento para su preparacion.

Info

Publication number
ES2118677T1
ES2118677T1 ES96921197T ES96921197T ES2118677T1 ES 2118677 T1 ES2118677 T1 ES 2118677T1 ES 96921197 T ES96921197 T ES 96921197T ES 96921197 T ES96921197 T ES 96921197T ES 2118677 T1 ES2118677 T1 ES 2118677T1
Authority
ES
Spain
Prior art keywords
active agent
composition
pct
glass
vitrificing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES96921197T
Other languages
English (en)
Other versions
ES2118677T3 (es
Inventor
Ake Lindahl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioglan AB
Original Assignee
Bioglan AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioglan AB filed Critical Bioglan AB
Publication of ES2118677T1 publication Critical patent/ES2118677T1/es
Application granted granted Critical
Publication of ES2118677T3 publication Critical patent/ES2118677T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Glass Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Processing Of Solid Wastes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

FORMULACION BIOLOGICAMENTE ACTIVA COMPUESTA DE UNA SOLUCION DE UN AGENTE ACTIVO DISUELTO EN UN VEHICULO VITRIFICANTE, QUE CONTIENE UNA SUSTANCIA VITRIFICANTE (A) CON UN PLASTIFICANTE (B) CUYA CANTIDAD DEBE SELECCIONARSE PREFERIBLEMENTE DE FORMA QUE LA FORMULACION ADQUIERA UNA CONSISTENCIA NO SOLIDA. LA FORMULACION PUEDE PREPARARSE DISOLVIENDO EL AGENTE ACTIVO EN UNA MEZCLA FUNDIDA DE LA SUSTANCIA VITRIFICANTE Y EL PLASTIFICANTE A UNA TEMPERATURA INFERIOR A LA TEMPERATURA DE DESINTEGRACION DEL AGENTE ACTIVO REFERIDO. UTILIZACION DEL VEHICULO VITRIFICANTE PARA LA DISOLUCION DE UN AGENTE BIOLOGICAMENTE ACTIVO.
ES96921197T 1995-06-20 1996-06-19 Una composicion que comprende un agente activo disuelto en un vehiculo formador de vidrio y un procedimiento para su preparacion. Expired - Lifetime ES2118677T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9502244A SE9502244D0 (sv) 1995-06-20 1995-06-20 A composition and a process for the preparation thereof

Publications (2)

Publication Number Publication Date
ES2118677T1 true ES2118677T1 (es) 1998-10-01
ES2118677T3 ES2118677T3 (es) 2001-10-16

Family

ID=20398685

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96921197T Expired - Lifetime ES2118677T3 (es) 1995-06-20 1996-06-19 Una composicion que comprende un agente activo disuelto en un vehiculo formador de vidrio y un procedimiento para su preparacion.

Country Status (15)

Country Link
US (1) US6083518A (es)
EP (1) EP0833611B1 (es)
JP (1) JP4020331B2 (es)
AT (1) ATE204466T1 (es)
AU (1) AU695622B2 (es)
CA (1) CA2225286C (es)
DE (2) DE833611T1 (es)
DK (1) DK0833611T3 (es)
ES (1) ES2118677T3 (es)
HK (1) HK1008774A1 (es)
NZ (1) NZ311208A (es)
PT (1) PT833611E (es)
SE (1) SE9502244D0 (es)
WO (1) WO1997000670A1 (es)
ZA (1) ZA965237B (es)

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Also Published As

Publication number Publication date
JP4020331B2 (ja) 2007-12-12
PT833611E (pt) 2002-01-30
JPH11508250A (ja) 1999-07-21
WO1997000670A1 (en) 1997-01-09
HK1008774A1 (en) 1999-05-21
ZA965237B (en) 1997-01-09
CA2225286A1 (en) 1997-01-09
DE69614689T2 (de) 2002-06-27
ATE204466T1 (de) 2001-09-15
AU6247396A (en) 1997-01-22
EP0833611B1 (en) 2001-08-22
ES2118677T3 (es) 2001-10-16
EP0833611A1 (en) 1998-04-08
US6083518A (en) 2000-07-04
NZ311208A (en) 1999-03-29
CA2225286C (en) 2003-06-10
SE9502244D0 (sv) 1995-06-20
DK0833611T3 (da) 2001-10-08
DE833611T1 (de) 1999-01-07
AU695622B2 (en) 1998-08-20
DE69614689D1 (de) 2001-09-27

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