ES2118263T3 - Dispositivo de liberacion que tiene excipientes encapsulados. - Google Patents
Dispositivo de liberacion que tiene excipientes encapsulados.Info
- Publication number
- ES2118263T3 ES2118263T3 ES93923796T ES93923796T ES2118263T3 ES 2118263 T3 ES2118263 T3 ES 2118263T3 ES 93923796 T ES93923796 T ES 93923796T ES 93923796 T ES93923796 T ES 93923796T ES 2118263 T3 ES2118263 T3 ES 2118263T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- solubility
- coated
- date
- beneficial agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
- Photoreceptors In Electrophotography (AREA)
Abstract
UN DISPOSITIVO DE DISTRIBUCION, OSMOTICO, DE MEMBRANA ASIMETRICA, QUE TIENE MODIFICADORES DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTOS. EL DISPOSITIVO COMPRENDE UN AGENTE BENEFICIOS, UN OSMAGENTE, UN MODIFICADOR DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTO Y UNA MEMBRANA ASIMETRICA QUE RODEA LOS COMPONENTES DEL DISPOSITIVO. EL DISPOSITIVO ES UTIL PARA DISTRIBUIR UN AGENTE BENEFICIOSO A UN AMBIENTE ACUOSO DE APLICACION. LAS MACROPARTICULAS CUBIERTAS MODIFICAN LA SOLUBILIDAD DEL AGENTE BENEFICIOSO TAL QUE SU LIBERACION PUEDA SER CONTROLADA. EL TAMAÑO MAS GRANDE DE LAS MACROPARTICULAS MODIFICADORAS DE SOLUBILIDAD PROVEE, POR EJEMPLO, UNA DURACION DE LA LIBERACION MAS GRANDE QUE HUBIERA SIDO POSIBLE CON UN TAMAÑO MAS PEQUEÑO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97972792A | 1992-11-20 | 1992-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2118263T3 true ES2118263T3 (es) | 1998-09-16 |
Family
ID=25527106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93923796T Expired - Lifetime ES2118263T3 (es) | 1992-11-20 | 1993-10-13 | Dispositivo de liberacion que tiene excipientes encapsulados. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5697922A (es) |
EP (1) | EP0668755B1 (es) |
JP (1) | JP2842944B2 (es) |
KR (1) | KR950703931A (es) |
CN (1) | CN1090488A (es) |
AT (1) | ATE168886T1 (es) |
AU (1) | AU5353694A (es) |
CA (1) | CA2148837C (es) |
DE (1) | DE69320056T2 (es) |
DK (1) | DK0668755T3 (es) |
ES (1) | ES2118263T3 (es) |
FI (1) | FI113940B (es) |
GR (1) | GR3027676T3 (es) |
IL (1) | IL107567A0 (es) |
MX (1) | MX9307256A (es) |
MY (1) | MY134742A (es) |
NO (1) | NO311403B1 (es) |
NZ (1) | NZ257239A (es) |
TW (1) | TW235239B (es) |
WO (1) | WO1994012152A1 (es) |
ZA (1) | ZA938656B (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6514533B1 (en) * | 1992-06-11 | 2003-02-04 | Alkermas Controlled Therapeutics, Inc. | Device for the sustained release of aggregation-stabilized, biologically active agent |
IN186245B (es) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
US6391336B1 (en) | 1997-09-22 | 2002-05-21 | Royer Biomedical, Inc. | Inorganic-polymer complexes for the controlled release of compounds including medicinals |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
US6448323B1 (en) * | 1999-07-09 | 2002-09-10 | Bpsi Holdings, Inc. | Film coatings and film coating compositions based on polyvinyl alcohol |
WO2003024427A1 (en) | 1999-12-20 | 2003-03-27 | Temple University Of The Commonwealth System Of Higher Education | Tableted oral extended release dosage form |
US6936275B2 (en) | 1999-12-20 | 2005-08-30 | Scolr, Inc. | Amino acid modulated extended release dosage form |
US6599532B2 (en) * | 2000-01-13 | 2003-07-29 | Osmotica Corp. | Osmotic device containing alprazolam and an antipsychotic agent |
US20030175349A1 (en) * | 2001-01-30 | 2003-09-18 | Council Of Scientific And Industrial Research | Pharmaceutical compostion for extended/sustained release of a therapeutically active ingredient |
DE60223695T2 (de) * | 2001-09-14 | 2008-10-30 | Scolr, Inc., Redmond | Aminosäure-modulierte dosierform mit verlängerter freisetzung |
JP2004075582A (ja) * | 2002-08-13 | 2004-03-11 | Takeda Chem Ind Ltd | 固形医薬組成物に処方される有効成分以外の成分の安定化方法 |
US8980870B2 (en) * | 2002-09-24 | 2015-03-17 | Boehringer Ingelheim International Gmbh | Solid telmisartan pharmaceutical formulations |
US6893660B2 (en) * | 2002-11-21 | 2005-05-17 | Andrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions without a stabilizer |
US20050053669A1 (en) * | 2003-09-05 | 2005-03-10 | Boehringer Ingelheim International Gmbh | Administration form for the oral application of poorly soluble acidic and amphorteric drugs |
US7611728B2 (en) * | 2003-09-05 | 2009-11-03 | Supernus Pharmaceuticals, Inc. | Osmotic delivery of therapeutic compounds by solubility enhancement |
WO2005124931A1 (en) * | 2004-06-08 | 2005-12-29 | Paricon Technologies Corporation | Apparatus for applying a mechanically-releasable balanced compressive load to an assembly such as a compliant anisotropic conductive elastomer electrical connector |
US20060068010A1 (en) * | 2004-09-30 | 2006-03-30 | Stephen Turner | Method for improving the bioavailability of orally delivered therapeutics |
US8637078B2 (en) * | 2005-11-24 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Bilayer tablet comprising telmisartan and diuretic |
EP1837364A1 (fr) * | 2006-03-20 | 2007-09-26 | A. Weber (Société Anonyme) | Procédé de neutralisation de l'acidité résiduelle contenue dans les composés phénoliques |
US8747897B2 (en) | 2006-04-27 | 2014-06-10 | Supernus Pharmaceuticals, Inc. | Osmotic drug delivery system |
CN101374497A (zh) * | 2006-05-08 | 2009-02-25 | 麦克内尔-Ppc股份有限公司 | 渗透剂型 |
JP2012505211A (ja) * | 2008-10-10 | 2012-03-01 | アルヴィン ファーマシューティカルズ インコーポレーティッド | チモーゲンの迅速な活性化を促進する剤形 |
US20100266682A1 (en) * | 2008-12-10 | 2010-10-21 | Nipun Davar | Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same |
US20100143486A1 (en) * | 2008-12-10 | 2010-06-10 | Nipun Davar | Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same |
EP2228066A1 (en) * | 2009-03-03 | 2010-09-15 | LEK Pharmaceuticals d.d. | Pharmaceutical compositions of sulphonylurea-based active pharmaceutical ingredient with excellent dissolution properties |
CN102113961B (zh) * | 2011-01-25 | 2013-11-13 | 浙江工业大学 | 一种不对称膜渗透泵胶囊壳的制备方法 |
EP3055403B1 (en) * | 2013-10-07 | 2020-08-26 | Monosol, LLC | Water-soluble delayed release capsules, related methods, and related articles |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4111203A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system with means for improving delivery kinetics of system |
US4111201A (en) * | 1976-11-22 | 1978-09-05 | Alza Corporation | Osmotic system for delivering selected beneficial agents having varying degrees of solubility |
US4608048A (en) * | 1984-12-06 | 1986-08-26 | Alza Corporation | Dispensing device with drug delivery patterns |
US4755180A (en) * | 1986-06-16 | 1988-07-05 | Alza Corporation | Dosage form comprising solubility regulating member |
IL91398A (en) * | 1988-08-30 | 1994-05-30 | Pfizer | A device for the controlled release of pneumatic substances, including the active substance, surrounded by an asymmetric membrane |
US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
US5225202A (en) * | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
-
1993
- 1993-10-08 TW TW082108360A patent/TW235239B/zh active
- 1993-10-13 NZ NZ257239A patent/NZ257239A/en unknown
- 1993-10-13 ES ES93923796T patent/ES2118263T3/es not_active Expired - Lifetime
- 1993-10-13 DE DE69320056T patent/DE69320056T2/de not_active Expired - Fee Related
- 1993-10-13 JP JP6513114A patent/JP2842944B2/ja not_active Expired - Fee Related
- 1993-10-13 AU AU53536/94A patent/AU5353694A/en not_active Abandoned
- 1993-10-13 CA CA002148837A patent/CA2148837C/en not_active Expired - Fee Related
- 1993-10-13 AT AT93923796T patent/ATE168886T1/de not_active IP Right Cessation
- 1993-10-13 DK DK93923796T patent/DK0668755T3/da active
- 1993-10-13 EP EP93923796A patent/EP0668755B1/en not_active Expired - Lifetime
- 1993-10-13 US US08/424,476 patent/US5697922A/en not_active Expired - Fee Related
- 1993-10-13 WO PCT/US1993/009582 patent/WO1994012152A1/en active IP Right Grant
- 1993-11-11 IL IL10756793A patent/IL107567A0/xx unknown
- 1993-11-19 ZA ZA938656A patent/ZA938656B/xx unknown
- 1993-11-19 CN CN93114529A patent/CN1090488A/zh active Pending
- 1993-11-19 MY MYPI93002433A patent/MY134742A/en unknown
- 1993-11-19 MX MX9307256A patent/MX9307256A/es unknown
-
1995
- 1995-05-19 NO NO19951996A patent/NO311403B1/no not_active IP Right Cessation
- 1995-05-19 KR KR1019950702025A patent/KR950703931A/ko not_active Application Discontinuation
- 1995-05-19 FI FI952461A patent/FI113940B/fi active
-
1998
- 1998-08-19 GR GR980401855T patent/GR3027676T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH07508762A (ja) | 1995-09-28 |
MY134742A (en) | 2007-12-31 |
FI952461A0 (fi) | 1995-05-19 |
EP0668755A1 (en) | 1995-08-30 |
US5697922A (en) | 1997-12-16 |
FI113940B (fi) | 2004-07-15 |
DE69320056D1 (de) | 1998-09-03 |
NO951996D0 (no) | 1995-05-19 |
WO1994012152A1 (en) | 1994-06-09 |
DE69320056T2 (de) | 1998-12-10 |
NO951996L (no) | 1995-05-19 |
CA2148837A1 (en) | 1994-06-09 |
GR3027676T3 (en) | 1998-11-30 |
JP2842944B2 (ja) | 1999-01-06 |
FI952461A (fi) | 1995-05-19 |
ZA938656B (en) | 1995-05-18 |
ATE168886T1 (de) | 1998-08-15 |
AU5353694A (en) | 1994-06-22 |
DK0668755T3 (da) | 1998-11-02 |
IL107567A0 (en) | 1994-02-27 |
NO311403B1 (no) | 2001-11-26 |
CN1090488A (zh) | 1994-08-10 |
NZ257239A (en) | 1996-08-27 |
TW235239B (es) | 1994-12-01 |
EP0668755B1 (en) | 1998-07-29 |
KR950703931A (ko) | 1995-11-17 |
MX9307256A (es) | 1994-05-31 |
CA2148837C (en) | 1998-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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