ES2118263T3 - Dispositivo de liberacion que tiene excipientes encapsulados. - Google Patents

Dispositivo de liberacion que tiene excipientes encapsulados.

Info

Publication number
ES2118263T3
ES2118263T3 ES93923796T ES93923796T ES2118263T3 ES 2118263 T3 ES2118263 T3 ES 2118263T3 ES 93923796 T ES93923796 T ES 93923796T ES 93923796 T ES93923796 T ES 93923796T ES 2118263 T3 ES2118263 T3 ES 2118263T3
Authority
ES
Spain
Prior art keywords
pct
solubility
coated
date
beneficial agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93923796T
Other languages
English (en)
Inventor
Avinash Govind Thombre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2118263T3 publication Critical patent/ES2118263T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
  • Photoreceptors In Electrophotography (AREA)

Abstract

UN DISPOSITIVO DE DISTRIBUCION, OSMOTICO, DE MEMBRANA ASIMETRICA, QUE TIENE MODIFICADORES DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTOS. EL DISPOSITIVO COMPRENDE UN AGENTE BENEFICIOS, UN OSMAGENTE, UN MODIFICADOR DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTO Y UNA MEMBRANA ASIMETRICA QUE RODEA LOS COMPONENTES DEL DISPOSITIVO. EL DISPOSITIVO ES UTIL PARA DISTRIBUIR UN AGENTE BENEFICIOSO A UN AMBIENTE ACUOSO DE APLICACION. LAS MACROPARTICULAS CUBIERTAS MODIFICAN LA SOLUBILIDAD DEL AGENTE BENEFICIOSO TAL QUE SU LIBERACION PUEDA SER CONTROLADA. EL TAMAÑO MAS GRANDE DE LAS MACROPARTICULAS MODIFICADORAS DE SOLUBILIDAD PROVEE, POR EJEMPLO, UNA DURACION DE LA LIBERACION MAS GRANDE QUE HUBIERA SIDO POSIBLE CON UN TAMAÑO MAS PEQUEÑO.
ES93923796T 1992-11-20 1993-10-13 Dispositivo de liberacion que tiene excipientes encapsulados. Expired - Lifetime ES2118263T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97972792A 1992-11-20 1992-11-20

Publications (1)

Publication Number Publication Date
ES2118263T3 true ES2118263T3 (es) 1998-09-16

Family

ID=25527106

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93923796T Expired - Lifetime ES2118263T3 (es) 1992-11-20 1993-10-13 Dispositivo de liberacion que tiene excipientes encapsulados.

Country Status (21)

Country Link
US (1) US5697922A (es)
EP (1) EP0668755B1 (es)
JP (1) JP2842944B2 (es)
KR (1) KR950703931A (es)
CN (1) CN1090488A (es)
AT (1) ATE168886T1 (es)
AU (1) AU5353694A (es)
CA (1) CA2148837C (es)
DE (1) DE69320056T2 (es)
DK (1) DK0668755T3 (es)
ES (1) ES2118263T3 (es)
FI (1) FI113940B (es)
GR (1) GR3027676T3 (es)
IL (1) IL107567A0 (es)
MX (1) MX9307256A (es)
MY (1) MY134742A (es)
NO (1) NO311403B1 (es)
NZ (1) NZ257239A (es)
TW (1) TW235239B (es)
WO (1) WO1994012152A1 (es)
ZA (1) ZA938656B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514533B1 (en) * 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6448323B1 (en) * 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
WO2003024427A1 (en) 1999-12-20 2003-03-27 Temple University Of The Commonwealth System Of Higher Education Tableted oral extended release dosage form
US6936275B2 (en) 1999-12-20 2005-08-30 Scolr, Inc. Amino acid modulated extended release dosage form
US6599532B2 (en) * 2000-01-13 2003-07-29 Osmotica Corp. Osmotic device containing alprazolam and an antipsychotic agent
US20030175349A1 (en) * 2001-01-30 2003-09-18 Council Of Scientific And Industrial Research Pharmaceutical compostion for extended/sustained release of a therapeutically active ingredient
DE60223695T2 (de) * 2001-09-14 2008-10-30 Scolr, Inc., Redmond Aminosäure-modulierte dosierform mit verlängerter freisetzung
JP2004075582A (ja) * 2002-08-13 2004-03-11 Takeda Chem Ind Ltd 固形医薬組成物に処方される有効成分以外の成分の安定化方法
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
WO2005124931A1 (en) * 2004-06-08 2005-12-29 Paricon Technologies Corporation Apparatus for applying a mechanically-releasable balanced compressive load to an assembly such as a compliant anisotropic conductive elastomer electrical connector
US20060068010A1 (en) * 2004-09-30 2006-03-30 Stephen Turner Method for improving the bioavailability of orally delivered therapeutics
US8637078B2 (en) * 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
EP1837364A1 (fr) * 2006-03-20 2007-09-26 A. Weber (Société Anonyme) Procédé de neutralisation de l'acidité résiduelle contenue dans les composés phénoliques
US8747897B2 (en) 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
CN101374497A (zh) * 2006-05-08 2009-02-25 麦克内尔-Ppc股份有限公司 渗透剂型
JP2012505211A (ja) * 2008-10-10 2012-03-01 アルヴィン ファーマシューティカルズ インコーポレーティッド チモーゲンの迅速な活性化を促進する剤形
US20100266682A1 (en) * 2008-12-10 2010-10-21 Nipun Davar Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same
US20100143486A1 (en) * 2008-12-10 2010-06-10 Nipun Davar Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same
EP2228066A1 (en) * 2009-03-03 2010-09-15 LEK Pharmaceuticals d.d. Pharmaceutical compositions of sulphonylurea-based active pharmaceutical ingredient with excellent dissolution properties
CN102113961B (zh) * 2011-01-25 2013-11-13 浙江工业大学 一种不对称膜渗透泵胶囊壳的制备方法
EP3055403B1 (en) * 2013-10-07 2020-08-26 Monosol, LLC Water-soluble delayed release capsules, related methods, and related articles

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4111203A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4111201A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for delivering selected beneficial agents having varying degrees of solubility
US4608048A (en) * 1984-12-06 1986-08-26 Alza Corporation Dispensing device with drug delivery patterns
US4755180A (en) * 1986-06-16 1988-07-05 Alza Corporation Dosage form comprising solubility regulating member
IL91398A (en) * 1988-08-30 1994-05-30 Pfizer A device for the controlled release of pneumatic substances, including the active substance, surrounded by an asymmetric membrane
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
US5260068A (en) * 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system

Also Published As

Publication number Publication date
JPH07508762A (ja) 1995-09-28
MY134742A (en) 2007-12-31
FI952461A0 (fi) 1995-05-19
EP0668755A1 (en) 1995-08-30
US5697922A (en) 1997-12-16
FI113940B (fi) 2004-07-15
DE69320056D1 (de) 1998-09-03
NO951996D0 (no) 1995-05-19
WO1994012152A1 (en) 1994-06-09
DE69320056T2 (de) 1998-12-10
NO951996L (no) 1995-05-19
CA2148837A1 (en) 1994-06-09
GR3027676T3 (en) 1998-11-30
JP2842944B2 (ja) 1999-01-06
FI952461A (fi) 1995-05-19
ZA938656B (en) 1995-05-18
ATE168886T1 (de) 1998-08-15
AU5353694A (en) 1994-06-22
DK0668755T3 (da) 1998-11-02
IL107567A0 (en) 1994-02-27
NO311403B1 (no) 2001-11-26
CN1090488A (zh) 1994-08-10
NZ257239A (en) 1996-08-27
TW235239B (es) 1994-12-01
EP0668755B1 (en) 1998-07-29
KR950703931A (ko) 1995-11-17
MX9307256A (es) 1994-05-31
CA2148837C (en) 1998-07-14

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