ES2118263T3 - Dispositivo de liberacion que tiene excipientes encapsulados. - Google Patents

Dispositivo de liberacion que tiene excipientes encapsulados.

Info

Publication number
ES2118263T3
ES2118263T3 ES93923796T ES93923796T ES2118263T3 ES 2118263 T3 ES2118263 T3 ES 2118263T3 ES 93923796 T ES93923796 T ES 93923796T ES 93923796 T ES93923796 T ES 93923796T ES 2118263 T3 ES2118263 T3 ES 2118263T3
Authority
ES
Spain
Prior art keywords
solubility
macroparticles
covered
release device
beneficial agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93923796T
Other languages
English (en)
Inventor
Avinash Govind Thombre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of ES2118263T3 publication Critical patent/ES2118263T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

UN DISPOSITIVO DE DISTRIBUCION, OSMOTICO, DE MEMBRANA ASIMETRICA, QUE TIENE MODIFICADORES DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTOS. EL DISPOSITIVO COMPRENDE UN AGENTE BENEFICIOS, UN OSMAGENTE, UN MODIFICADOR DE SOLUBILIDAD DE MACROPARTICULAS CUBIERTO Y UNA MEMBRANA ASIMETRICA QUE RODEA LOS COMPONENTES DEL DISPOSITIVO. EL DISPOSITIVO ES UTIL PARA DISTRIBUIR UN AGENTE BENEFICIOSO A UN AMBIENTE ACUOSO DE APLICACION. LAS MACROPARTICULAS CUBIERTAS MODIFICAN LA SOLUBILIDAD DEL AGENTE BENEFICIOSO TAL QUE SU LIBERACION PUEDA SER CONTROLADA. EL TAMAÑO MAS GRANDE DE LAS MACROPARTICULAS MODIFICADORAS DE SOLUBILIDAD PROVEE, POR EJEMPLO, UNA DURACION DE LA LIBERACION MAS GRANDE QUE HUBIERA SIDO POSIBLE CON UN TAMAÑO MAS PEQUEÑO.
ES93923796T 1992-11-20 1993-10-13 Dispositivo de liberacion que tiene excipientes encapsulados. Expired - Lifetime ES2118263T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US97972792A 1992-11-20 1992-11-20

Publications (1)

Publication Number Publication Date
ES2118263T3 true ES2118263T3 (es) 1998-09-16

Family

ID=25527106

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93923796T Expired - Lifetime ES2118263T3 (es) 1992-11-20 1993-10-13 Dispositivo de liberacion que tiene excipientes encapsulados.

Country Status (21)

Country Link
US (1) US5697922A (es)
EP (1) EP0668755B1 (es)
JP (1) JP2842944B2 (es)
KR (1) KR950703931A (es)
CN (1) CN1090488A (es)
AT (1) ATE168886T1 (es)
AU (1) AU5353694A (es)
CA (1) CA2148837C (es)
DE (1) DE69320056T2 (es)
DK (1) DK0668755T3 (es)
ES (1) ES2118263T3 (es)
FI (1) FI113940B (es)
GR (1) GR3027676T3 (es)
IL (1) IL107567A0 (es)
MX (1) MX9307256A (es)
MY (1) MY134742A (es)
NO (1) NO311403B1 (es)
NZ (1) NZ257239A (es)
TW (1) TW235239B (es)
WO (1) WO1994012152A1 (es)
ZA (1) ZA938656B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514533B1 (en) * 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
IN186245B (es) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6391336B1 (en) 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US6448323B1 (en) * 1999-07-09 2002-09-10 Bpsi Holdings, Inc. Film coatings and film coating compositions based on polyvinyl alcohol
WO2003024427A1 (en) 1999-12-20 2003-03-27 Temple University Of The Commonwealth System Of Higher Education Tableted oral extended release dosage form
US6936275B2 (en) 1999-12-20 2005-08-30 Scolr, Inc. Amino acid modulated extended release dosage form
US6599532B2 (en) * 2000-01-13 2003-07-29 Osmotica Corp. Osmotic device containing alprazolam and an antipsychotic agent
US20030175349A1 (en) * 2001-01-30 2003-09-18 Council Of Scientific And Industrial Research Pharmaceutical compostion for extended/sustained release of a therapeutically active ingredient
PT1424997E (pt) * 2001-09-14 2008-02-28 Scolr Inc Forma de dosagem de libertação prolongada modulada por aminoácidos
JP2004075582A (ja) * 2002-08-13 2004-03-11 Takeda Chem Ind Ltd 固形医薬組成物に処方される有効成分以外の成分の安定化方法
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
WO2005124931A1 (en) * 2004-06-08 2005-12-29 Paricon Technologies Corporation Apparatus for applying a mechanically-releasable balanced compressive load to an assembly such as a compliant anisotropic conductive elastomer electrical connector
US20060068010A1 (en) * 2004-09-30 2006-03-30 Stephen Turner Method for improving the bioavailability of orally delivered therapeutics
US8637078B2 (en) * 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
EP1837364A1 (fr) * 2006-03-20 2007-09-26 A. Weber (Société Anonyme) Procédé de neutralisation de l'acidité résiduelle contenue dans les composés phénoliques
US8747897B2 (en) 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
CA2612989A1 (en) * 2006-05-08 2007-11-08 Mcneil-Ppc, Inc. Osmotic dosage form
EP2344183B1 (en) * 2008-10-10 2015-02-25 Alvine Pharmaceuticals, Inc. Dosage forms that facilitate rapid activation of zymogen
US20100266682A1 (en) * 2008-12-10 2010-10-21 Nipun Davar Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same
US20100143486A1 (en) * 2008-12-10 2010-06-10 Nipun Davar Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same
EP2228066A1 (en) * 2009-03-03 2010-09-15 LEK Pharmaceuticals d.d. Pharmaceutical compositions of sulphonylurea-based active pharmaceutical ingredient with excellent dissolution properties
CN102113961B (zh) * 2011-01-25 2013-11-13 浙江工业大学 一种不对称膜渗透泵胶囊壳的制备方法
JP6691478B2 (ja) * 2013-10-07 2020-04-28 モノソル リミテッド ライアビリティ カンパニー 水溶性遅延放出カプセル、関連する方法および関連する物品
US20250049743A1 (en) 2023-08-08 2025-02-13 United Therapeutics Corporation Method of producing an oral osmotic pharmaceutical delivery system and a pharmaceutical batch produced using the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4111201A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for delivering selected beneficial agents having varying degrees of solubility
US4111203A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system with means for improving delivery kinetics of system
US4608048A (en) * 1984-12-06 1986-08-26 Alza Corporation Dispensing device with drug delivery patterns
US4755180A (en) * 1986-06-16 1988-07-05 Alza Corporation Dosage form comprising solubility regulating member
IL91398A (en) * 1988-08-30 1994-05-30 Pfizer Pharmaceutical delivery device comprising active substance surrounded by asymmetric membrane
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
US5260068A (en) * 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system

Also Published As

Publication number Publication date
NO951996D0 (no) 1995-05-19
EP0668755A1 (en) 1995-08-30
MY134742A (en) 2007-12-31
JP2842944B2 (ja) 1999-01-06
NO951996L (no) 1995-05-19
CN1090488A (zh) 1994-08-10
DE69320056T2 (de) 1998-12-10
FI113940B (fi) 2004-07-15
KR950703931A (ko) 1995-11-17
MX9307256A (es) 1994-05-31
FI952461L (fi) 1995-05-19
ATE168886T1 (de) 1998-08-15
NO311403B1 (no) 2001-11-26
WO1994012152A1 (en) 1994-06-09
AU5353694A (en) 1994-06-22
FI952461A0 (fi) 1995-05-19
US5697922A (en) 1997-12-16
IL107567A0 (en) 1994-02-27
NZ257239A (en) 1996-08-27
TW235239B (es) 1994-12-01
GR3027676T3 (en) 1998-11-30
DE69320056D1 (de) 1998-09-03
ZA938656B (en) 1995-05-18
JPH07508762A (ja) 1995-09-28
CA2148837A1 (en) 1994-06-09
EP0668755B1 (en) 1998-07-29
CA2148837C (en) 1998-07-14
DK0668755T3 (da) 1998-11-02

Similar Documents

Publication Publication Date Title
ES2118263T3 (es) Dispositivo de liberacion que tiene excipientes encapsulados.
ES2156413T3 (es) Sifon autocebante, especialmente para riego.
ES2171971T3 (es) Producto limpiador y de tratamiento con almidon.
ES2117646T3 (es) Alteracion de la velocidad y el caracter del crecimiento del pelo.
CO4820399A1 (es) Material absorbente y metodo de obtencion . .
ES2152281T3 (es) Fabricacion de capsulas de gelatina blanda.
ES2068536T3 (es) Dispositivo para la preparacion extemporanea y continuada de dializado.
ES2107235T3 (es) Tableta de liberacion prolongada, revestida con pelicula, de astemizol y pseudoefedrina.
ES2127212T3 (es) Estructura de soporte logico para sistemas conmutadores de telecomunicaciones.
AR004790A1 (es) Reduccion del crecimiento del pelo
BR0110751A (pt) Dispositivo
ES2032356A1 (es) Cebo envenenado para la erradicacion de insectos nocivos.
GT197642549A (es) Procedimiento para controlar cucarachas y otros insectos quese arrastran
AR241747A1 (es) Dispositivo de bolo de liberacion controlada.
ES2046852T3 (es) Un procedimiento para preparar un champu.
ES2086006T3 (es) Injerto atravesado por un paso.
ES2070358T3 (es) Dispositivo para enclavar un espadin de aguja de ferrocarril.
ES2103924T3 (es) Un cuerpo portador de barra de labios con un mecanismo para su impulsion.
ES2045074T3 (es) Empleo de compuestos que contengan bisguanidos contra las huevas del oxiuro vermicular.
AR006801A1 (es) Una composicion para el acondicionamiento de la piel que contiene melinamida , retinol y/o ester de retinilo, y un metodo cosmetico no terapeutico para el acondicionamiento de la piel que comprende la aplicacion de dicha composicion.
ES2076320T3 (es) Adyuvante angiografico.
MY111718A (en) Deuterated active substances in transdermal application
ES2159013T3 (es) Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion.
ES2097423T3 (es) Analogos de vitamina d3.
ES2130598T3 (es) Preparaciones cosmeticas y/o farmaceuticas.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 668755

Country of ref document: ES