ES2159013T3 - Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion. - Google Patents

Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion.

Info

Publication number
ES2159013T3
ES2159013T3 ES96900973T ES96900973T ES2159013T3 ES 2159013 T3 ES2159013 T3 ES 2159013T3 ES 96900973 T ES96900973 T ES 96900973T ES 96900973 T ES96900973 T ES 96900973T ES 2159013 T3 ES2159013 T3 ES 2159013T3
Authority
ES
Spain
Prior art keywords
wounds
release
colagenasa
elaboration
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96900973T
Other languages
English (en)
Inventor
Michael Roreger
Heinz Einig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll GmbH filed Critical Knoll GmbH
Application granted granted Critical
Publication of ES2159013T3 publication Critical patent/ES2159013T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/38—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UNA FORMA MEDICAMENTOSA PARA APLICAR COLAGENASA EN HERIDAS, QUE SE CARACTERIZA POR TENER UNA COMBINACION DE LAS SIGUIENTES PROPIEDADES: A) ES COHERENTE, SUPERFICIAL Y DEFORMABLE; B) ESTA DISEÑADA PARA SER IGUAL O MAS PEQUEÑA QUE LA SUPERFICIE DE LA HERIDA A TRATAR; C) CONTIENE UNAS CANTIDADES DEFINIDAS DE COLAGENASA DISTRIBUIDA DE FORMA HOMOGENEA; D) ESTA CONFORMADA PARA QUE LIBERE COLAGENASA DE UN MODO CONTROLADO.
ES96900973T 1995-02-02 1996-01-25 Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion. Expired - Lifetime ES2159013T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19503338A DE19503338C2 (de) 1995-02-02 1995-02-02 Arzneiform zur Abgabe von Kollagenase an Wunden und Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
ES2159013T3 true ES2159013T3 (es) 2001-09-16

Family

ID=7752981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96900973T Expired - Lifetime ES2159013T3 (es) 1995-02-02 1996-01-25 Forma farmaceutica para la liberacion de colagenasa en heridas y procedimiento para su elaboracion.

Country Status (27)

Country Link
US (1) US6074664A (es)
EP (1) EP0809489B1 (es)
JP (1) JP2000515485A (es)
KR (1) KR19980701888A (es)
CN (1) CN1182364A (es)
AR (1) AR001078A1 (es)
AT (1) ATE201136T1 (es)
AU (1) AU707364B2 (es)
BG (1) BG101802A (es)
BR (1) BR9606997A (es)
CA (1) CA2212059A1 (es)
CZ (1) CZ290943B6 (es)
DE (2) DE19503338C2 (es)
DK (1) DK0809489T3 (es)
ES (1) ES2159013T3 (es)
FI (1) FI972949A (es)
GR (1) GR3036384T3 (es)
HU (1) HUP0202088A2 (es)
MX (1) MX9705806A (es)
NO (1) NO973525L (es)
NZ (1) NZ300202A (es)
PL (1) PL182849B1 (es)
PT (1) PT809489E (es)
SK (1) SK282578B6 (es)
TR (1) TR199700734T1 (es)
WO (1) WO1996023487A1 (es)
ZA (1) ZA96795B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19710190A1 (de) * 1997-03-12 1998-09-17 Immuno Ag Aktivierter Vitamin K-abhängiger Blutfaktor und Verfahren zu dessen Herstellung
DE19829789A1 (de) * 1998-07-03 2000-01-05 Beiersdorf Ag Gegen Akne und entzündete Comedonen wirksame Zubereitungen enthaltend Serin-Proteasen und ein oder mehrere Calciumsalze
IL127209A0 (en) * 1998-11-23 1999-09-22 Bio Silk Ltd Composition and method for treatment of hypertrophic skin accumulations and their prevention
US7632494B2 (en) * 1999-09-24 2009-12-15 Proteon Therapeutics, Inc. Methods for enlarging the diameter of a biological conduit in a human subject
US7063838B1 (en) * 1999-09-24 2006-06-20 Proteon Therapeutics Llc Methods for treating an artery or vein in a human subject
US6756051B1 (en) * 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
DE10117916C2 (de) * 2001-04-10 2003-03-20 Christa Stolz Faltbares mit Creme beschichtetes Folienelement (Folienschuh) zur hygienischen Aufbringung von Fußcreme bei der Anwendung von mechanischen Fußmassagevorrichtungen
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
ES2613495T3 (es) 2009-12-08 2017-05-24 Smith & Nephew Orthopaedics Ag Composiciones de desbridamiento enzimático de heridas con actividad enzimática mejorada
AU2012385956B2 (en) 2012-07-23 2017-03-30 Crayola, Llc Dissolvable films and methods of using the same
US20150196625A9 (en) 2013-01-07 2015-07-16 Rudolph D. Paladini Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof
US10137179B2 (en) 2016-05-18 2018-11-27 Hyalo Technologies, LLC Composition and method of preparation of protease microparticulate slow release preparation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2432925C3 (de) * 1974-07-05 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen Folienförmige Arzneimittel
FR2488797A1 (fr) * 1980-08-19 1982-02-26 Lhd Lab Hygiene Dietetique Composition dermatologique, son procede de preparation et son application dans le domaine des pansements
ZA818919B (en) * 1981-04-13 1982-11-24 Seton Co Cosmetic and pharmaceutical sheet material containing polypeptides
DE3139089A1 (de) * 1981-10-01 1983-04-14 Röhm Pharma GmbH, 6100 Darmstadt Flaechengebilde auf proteinbasis als traeger therapeutisch wirksamer, nicht-immobilisierter enzyme
GB2150833B (en) * 1983-12-08 1987-04-15 Ceskoslovenska Akademie Ved Proteolytic wounds dressing
CA1256772A (en) * 1985-02-26 1989-07-04 Sudhakar S. Wagle Bandage for the topical administration of controlled amounts of nitroglycerin ointment
US4668228A (en) * 1985-03-12 1987-05-26 Johnson & Johnson Products, Inc. Debriding tape
DE3606265A1 (de) * 1986-02-27 1987-09-03 Roehm Pharma Gmbh Wundauflage auf polysaccharidbasis als traeger therapeutisch wirksamer, nicht-immobilisierter enzyme und mit hoher saugfaehigkeit
DE3630603A1 (de) * 1986-09-09 1988-03-10 Desitin Arzneimittel Gmbh Darreichungs- und dosierungsform fuer arzneimittelwirkstoffe, reagentien oder dergleichen sowie verfahren zu deren herstellung
DE3631413A1 (de) * 1986-09-16 1988-03-24 Knoll Ag Therapeutisches system zur lokalen applikation von pharmawirkstoffen
US5227157A (en) * 1986-10-14 1993-07-13 Board Of Regents, The University Of Texas System Delivery of therapeutic agents
DE8709810U1 (de) * 1987-07-16 1987-10-08 E.R. Squibb & Sons, Inc., Princeton, N.J. Medizinisches Pflaster
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5206026A (en) * 1988-05-24 1993-04-27 Sharik Clyde L Instantaneous delivery film
DE8902311U1 (de) * 1989-02-27 1989-05-11 Berg, Heide von, 8000 München Heilpflaster
US5393792A (en) * 1991-11-20 1995-02-28 Advance Biofactures Of Curacao, N.V. High dosage topical forms of collagenase
DE4230589C1 (de) * 1992-09-12 1994-02-03 Lohmann Therapie Syst Lts Dosierverfahren für leicht flüchtige oder thermolabile Substanzen in flüssiger Form zur Herstellung von u.a. flächigen Arzneiformen, insbesondere zur Herstellung von transdermalen oder dermalen therapeutischen Systemen
IL104734A0 (en) * 1993-02-15 1993-06-10 Univ Bar Ilan Bioactive conjugates of cellulose with amino compounds

Also Published As

Publication number Publication date
NO973525D0 (no) 1997-07-31
US6074664A (en) 2000-06-13
AR001078A1 (es) 1997-09-24
ZA96795B (en) 1996-07-16
FI972949A (fi) 1997-08-28
FI972949A0 (fi) 1997-07-11
DE19503338C2 (de) 1998-07-30
CN1182364A (zh) 1998-05-20
MX9705806A (es) 1998-07-31
NZ300202A (en) 1999-10-28
DE59606907D1 (de) 2001-06-21
GR3036384T3 (en) 2001-11-30
DE19503338A1 (de) 1996-08-08
BG101802A (en) 1998-02-27
NO973525L (no) 1997-07-31
CA2212059A1 (en) 1996-08-08
PT809489E (pt) 2001-10-31
WO1996023487A1 (de) 1996-08-08
AU707364B2 (en) 1999-07-08
HUP0202088A2 (en) 2002-09-28
EP0809489B1 (de) 2001-05-16
JP2000515485A (ja) 2000-11-21
AU4487396A (en) 1996-08-21
SK282578B6 (sk) 2002-10-08
DK0809489T3 (da) 2001-09-10
CZ221997A3 (en) 1997-12-17
ATE201136T1 (de) 2001-06-15
PL321810A1 (en) 1997-12-22
SK101597A3 (en) 1998-04-08
KR19980701888A (ko) 1998-06-25
PL182849B1 (pl) 2002-03-29
CZ290943B6 (cs) 2002-11-13
TR199700734T1 (xx) 1998-02-21
BR9606997A (pt) 1997-10-28
EP0809489A1 (de) 1997-12-03

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