CO5070580A1 - Formulacion farmaceutica para aerosoles con dos o mas sustancias activas - Google Patents

Formulacion farmaceutica para aerosoles con dos o mas sustancias activas

Info

Publication number
CO5070580A1
CO5070580A1 CO99037969A CO99037969A CO5070580A1 CO 5070580 A1 CO5070580 A1 CO 5070580A1 CO 99037969 A CO99037969 A CO 99037969A CO 99037969 A CO99037969 A CO 99037969A CO 5070580 A1 CO5070580 A1 CO 5070580A1
Authority
CO
Colombia
Prior art keywords
active substances
aerosols
propellant
pharmaceutical formulation
solvent
Prior art date
Application number
CO99037969A
Other languages
English (en)
Inventor
Mcnamara Daniel Parick
George Anthony Destefano
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26046888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5070580(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE1998127178 external-priority patent/DE19827178A1/de
Priority claimed from DE1998142963 external-priority patent/DE19842963A1/de
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of CO5070580A1 publication Critical patent/CO5070580A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Preparado farmacéutico para aerosoles dosificados, accionados por agente propelente con un hidrocarburo fluorado (HFA) como agente propelente, que contiene una combinación de sustancias activas, a base de dos o más sustancias activas, y que se caracteriza porque al menos una sustancia activa está disuelta en el agente propelente mediante la adición de un co-disolvente y, adicionalmente, al menos otra sustancia activa está suspendida en la mezcla de agente propelente y co-disolvente.
CO99037969A 1998-06-18 1999-06-17 Formulacion farmaceutica para aerosoles con dos o mas sustancias activas CO5070580A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998127178 DE19827178A1 (de) 1998-06-18 1998-06-18 Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen
DE1998142963 DE19842963A1 (de) 1998-09-19 1998-09-19 Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen

Publications (1)

Publication Number Publication Date
CO5070580A1 true CO5070580A1 (es) 2001-08-28

Family

ID=26046888

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99037969A CO5070580A1 (es) 1998-06-18 1999-06-17 Formulacion farmaceutica para aerosoles con dos o mas sustancias activas

Country Status (33)

Country Link
EP (1) EP1087750B1 (es)
JP (1) JP2003522102A (es)
KR (1) KR100600423B1 (es)
CN (1) CN1161104C (es)
AR (1) AR019690A1 (es)
AT (1) ATE253896T1 (es)
AU (1) AU759222B2 (es)
BG (1) BG65252B1 (es)
BR (1) BR9911351A (es)
CA (1) CA2335065C (es)
CO (1) CO5070580A1 (es)
CZ (1) CZ300910B6 (es)
DE (1) DE69912781T2 (es)
DK (1) DK1087750T3 (es)
EE (1) EE04450B1 (es)
ES (1) ES2211108T3 (es)
HK (1) HK1037974A1 (es)
HR (1) HRP20000867B1 (es)
HU (1) HU229064B1 (es)
ID (1) ID27554A (es)
IL (2) IL140353A0 (es)
ME (1) ME00838B (es)
MY (1) MY121073A (es)
NO (1) NO329416B1 (es)
NZ (1) NZ509418A (es)
PL (1) PL193695B1 (es)
PT (1) PT1087750E (es)
RS (1) RS49977B (es)
RU (1) RU2218152C2 (es)
SK (1) SK284756B6 (es)
TR (1) TR200003721T2 (es)
TW (1) TW528606B (es)
WO (1) WO1999065464A1 (es)

Families Citing this family (49)

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GB2332372B (en) * 1997-12-08 2002-08-14 Minnesota Mining & Mfg Pharmaceutical aerosol compositions
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
WO2001019342A2 (en) 1999-09-11 2001-03-22 Glaxo Group Limited Pharmaceutical formulation of fluticasone propionate
ATE286716T1 (de) * 1999-11-23 2005-01-15 Glaxo Group Ltd Pharmazeutische formulierungen enthaltend salmeterol
EP1248597B1 (en) * 1999-12-24 2005-03-30 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
GB0008485D0 (en) * 2000-04-07 2000-05-24 Glaxo Group Ltd Pharmaceutical compositions
BR0015884A (pt) * 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
SI1446119T1 (sl) 2001-09-18 2006-08-31 Nycomed Danmark Aps Sestavki, ki obsegajo ipratorij in ksilometazolin, za zdravljenje obicajnega prehlada
JP2010184937A (ja) * 2001-10-26 2010-08-26 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、キット、吸入溶液を中に有する１容器を作成する方法、および、吸入溶液を作成する方法
GB0207899D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and cielesonide aerosol formulations
EP1915985A1 (en) * 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US9308199B2 (en) * 2004-04-29 2016-04-12 Honeywell International Inc. Medicament formulations
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
CN103462894A (zh) * 2005-03-16 2013-12-25 霍尼韦尔国际公司 药物递送制剂、装置和方法
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
US8061350B2 (en) 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
ES2298049B1 (es) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2408500B1 (en) 2009-03-17 2015-04-29 Boehringer Ingelheim International GmbH Dispensing device, and storage device for dispensing a formulation
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
WO2011084316A2 (en) 2009-12-16 2011-07-14 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
EA032459B1 (ru) 2014-05-07 2019-05-31 Бёрингер Ингельхайм Интернациональ Гмбх Небулайзер
PL3139979T3 (pl) 2014-05-07 2023-12-27 Boehringer Ingelheim International Gmbh Jednostka, nebulizator i sposób
WO2020152548A1 (en) * 2019-01-24 2020-07-30 Glenmark Pharmaceuticals Limited Stable aerosol inhalation compositions of formoterol

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GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
DK0673240T3 (da) * 1992-12-09 1999-10-11 Boehringer Ingelheim Pharma Stabiliserede medicinske aerosolopløsningsformuleringer
US5589156A (en) * 1994-05-02 1996-12-31 Henry; Richard A. Prilocaine and hydrofluourocarbon aerosol preparations
US5603918A (en) * 1995-06-09 1997-02-18 Boehringer Ingelheim Pharmaceuticals, Inc. Aerosol composition of a salt of ipratropium and a salt of albuterol
AU3453897A (en) * 1996-07-08 1998-02-02 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation

Also Published As

Publication number Publication date
NO20006318D0 (no) 2000-12-12
MY121073A (en) 2005-12-30
ME00838B (me) 2008-09-29
SK19392000A3 (sk) 2001-07-10
KR20010072621A (ko) 2001-07-31
EP1087750B1 (en) 2003-11-12
TR200003721T2 (tr) 2001-06-21
BG65252B1 (bg) 2007-10-31
EE200000759A (et) 2002-04-15
EE04450B1 (et) 2005-04-15
NO20006318L (no) 2001-01-30
HUP0104734A3 (en) 2003-05-28
AR019690A1 (es) 2002-03-13
RU2218152C2 (ru) 2003-12-10
PT1087750E (pt) 2004-02-27
AU4552199A (en) 2000-01-05
PL193695B1 (pl) 2007-03-30
TW528606B (en) 2003-04-21
CZ300910B6 (cs) 2009-09-09
PL345685A1 (en) 2002-01-02
IL140353A (en) 2006-09-05
EP1087750A1 (en) 2001-04-04
SK284756B6 (sk) 2005-11-03
IL140353A0 (en) 2002-02-10
CA2335065A1 (en) 1999-12-23
DE69912781D1 (de) 2003-12-18
AU759222B2 (en) 2003-04-10
ATE253896T1 (de) 2003-11-15
CA2335065C (en) 2008-06-03
NZ509418A (en) 2003-06-30
RS49977B (sr) 2008-09-29
HRP20000867A2 (en) 2001-10-31
CZ20004750A3 (en) 2001-05-16
HK1037974A1 (en) 2002-03-01
HUP0104734A2 (hu) 2002-05-29
WO1999065464A1 (en) 1999-12-23
NO329416B1 (no) 2010-10-18
YU80000A (sh) 2003-04-30
BG105033A (en) 2001-09-28
BR9911351A (pt) 2001-03-13
CN1161104C (zh) 2004-08-11
CN1307470A (zh) 2001-08-08
JP2003522102A (ja) 2003-07-22
DK1087750T3 (da) 2004-01-26
KR100600423B1 (ko) 2006-07-13
ES2211108T3 (es) 2004-07-01
ID27554A (id) 2001-04-12
DE69912781T2 (de) 2004-10-21
HU229064B1 (en) 2013-07-29
HRP20000867B1 (en) 2010-10-31

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