YU80000A - Farmaceutske formulacije za aerosolove sa dve ili više aktivnih supstanci - Google Patents

Farmaceutske formulacije za aerosolove sa dve ili više aktivnih supstanci

Info

Publication number
YU80000A
YU80000A YU80000A YU80000A YU80000A YU 80000 A YU80000 A YU 80000A YU 80000 A YU80000 A YU 80000A YU 80000 A YU80000 A YU 80000A YU 80000 A YU80000 A YU 80000A
Authority
YU
Yugoslavia
Prior art keywords
aerosols
active substances
pharmaceutical formulations
active substance
propellant
Prior art date
Application number
YU80000A
Other languages
English (en)
Inventor
Daniel Patric Mcnamara
Stefano George De
Original Assignee
Boehringer Ingelheim Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26046888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU80000(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE1998127178 external-priority patent/DE19827178A1/de
Priority claimed from DE1998142963 external-priority patent/DE19842963A1/de
Application filed by Boehringer Ingelheim Pharmaceuticals Inc. filed Critical Boehringer Ingelheim Pharmaceuticals Inc.
Publication of YU80000A publication Critical patent/YU80000A/sh
Publication of RS49977B publication Critical patent/RS49977B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ovaj pronalazak odnosi se na nove farmaceutske formulacije za aerosole, sa bar dve ili više aktivnih supstanci, za primenu inhaliranjem ili nazalnim putem. Naročito, pronalazak se odnosi na farmaceutske preparate, koji se kao aerosolov potiskuju gasom, u odmerenoj dozi, upotrebom fluorougljovodonika (HFC) kao potisnog gasa, koji sadrže kombinaciju aktivne supstance od dve ili više aktivnih supstanci, pri čemu je bar jedna aktivna supstanca prisutna u rastvorenom obliku, zajedno sa bar jednom drugom aktivnom supstancom u obliku suspendovanih čestica.[The present invention relates to new pharmaceutical formulations for aerosols with at least two or more active substances for administration by inhalation or by nasal route. Specifically, the invention relates to pharmaceutical preparations for propellant-driven metered dose aerosols using a fluorohydrocarbon (HFC) as propellant, which contain a combination of active substance of two or more active substances, wherein at least one active substance is present in dissolved form together with at least one other active substance in the form of suspended particles.
YUP-800/00A 1998-06-18 1999-06-08 Farmaceutske formulacije za aerosolove sa dve ili više aktivnih supstanci RS49977B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998127178 DE19827178A1 (de) 1998-06-18 1998-06-18 Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen
DE1998142963 DE19842963A1 (de) 1998-09-19 1998-09-19 Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen

Publications (2)

Publication Number Publication Date
YU80000A true YU80000A (sh) 2003-04-30
RS49977B RS49977B (sr) 2008-09-29

Family

ID=26046888

Country Status (33)

Country Link
EP (1) EP1087750B1 (sh)
JP (1) JP2003522102A (sh)
KR (1) KR100600423B1 (sh)
CN (1) CN1161104C (sh)
AR (1) AR019690A1 (sh)
AT (1) ATE253896T1 (sh)
AU (1) AU759222B2 (sh)
BG (1) BG65252B1 (sh)
BR (1) BR9911351A (sh)
CA (1) CA2335065C (sh)
CO (1) CO5070580A1 (sh)
CZ (1) CZ300910B6 (sh)
DE (1) DE69912781T2 (sh)
DK (1) DK1087750T3 (sh)
EE (1) EE04450B1 (sh)
ES (1) ES2211108T3 (sh)
HK (1) HK1037974A1 (sh)
HR (1) HRP20000867B1 (sh)
HU (1) HU229064B1 (sh)
ID (1) ID27554A (sh)
IL (2) IL140353A0 (sh)
ME (1) ME00838B (sh)
MY (1) MY121073A (sh)
NO (1) NO329416B1 (sh)
NZ (1) NZ509418A (sh)
PL (1) PL193695B1 (sh)
PT (1) PT1087750E (sh)
RS (1) RS49977B (sh)
RU (1) RU2218152C2 (sh)
SK (1) SK284756B6 (sh)
TR (1) TR200003721T2 (sh)
TW (1) TW528606B (sh)
WO (1) WO1999065464A1 (sh)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB2332372B (en) * 1997-12-08 2002-08-14 Minnesota Mining & Mfg Pharmaceutical aerosol compositions
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
AU7026800A (en) 1999-09-11 2001-04-17 Glaxo Group Limited Pharmaceutical formulation of fluticasone propionate
JP2003514841A (ja) * 1999-11-23 2003-04-22 グラクソ グループ リミテッド サルメテロールの医薬製剤
ES2238334T3 (es) * 1999-12-24 2005-09-01 Glaxo Group Limited Formulacion farmaceutica en aerosol de salmeterol y propionato de fluticasona.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
GB0008485D0 (en) * 2000-04-07 2000-05-24 Glaxo Group Ltd Pharmaceutical compositions
IL152955A0 (en) 2000-05-22 2003-06-24 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurised metered dose inhalers
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
EP1661570A3 (en) 2001-09-18 2012-10-24 Nycomed Danmark ApS Compositions comprising ipatropium and xylometazoline for treatment of the common cold
JP2010184937A (ja) * 2001-10-26 2010-08-26 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、キット、吸入溶液を中に有する１容器を作成する方法、および、吸入溶液を作成する方法
GB0207899D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and cielesonide aerosol formulations
EP1915985A1 (en) * 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
US9308199B2 (en) * 2004-04-29 2016-04-12 Honeywell International Inc. Medicament formulations
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
JP2008546634A (ja) * 2005-03-16 2008-12-25 ハネウェル・インターナショナル・インコーポレーテッド 医薬送達製剤、デバイス及び方法
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
US8061350B2 (en) 2006-06-02 2011-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process and device for dosing pharmaceutical agents
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
ES2298049B1 (es) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2010105776A1 (en) 2009-03-17 2010-09-23 Boehringer Ingelheim International Gmbh Dispensing device, storage device and method for dispensing a formulation
JP5670421B2 (ja) 2009-03-31 2015-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング コンポーネント表面のコーティング方法
JP5763053B2 (ja) 2009-05-18 2015-08-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング アダプタ、吸入器具及びアトマイザ
AU2010323220B2 (en) 2009-11-25 2015-04-23 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011084316A2 (en) 2009-12-16 2011-07-14 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
JP6526057B2 (ja) 2014-05-07 2019-06-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ及び容器
HUE064131T2 (hu) 2014-05-07 2024-03-28 Boehringer Ingelheim Int Egység, porlasztó és eljárás
WO2020152548A1 (en) * 2019-01-24 2020-07-30 Glenmark Pharmaceuticals Limited Stable aerosol inhalation compositions of formoterol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
PL177078B1 (pl) * 1992-12-09 1999-09-30 Boehringer Ingelheim Pharma Preparaty roztworów aerozolowych
US5589156A (en) * 1994-05-02 1996-12-31 Henry; Richard A. Prilocaine and hydrofluourocarbon aerosol preparations
US5603918A (en) * 1995-06-09 1997-02-18 Boehringer Ingelheim Pharmaceuticals, Inc. Aerosol composition of a salt of ipratropium and a salt of albuterol
WO1998001147A1 (en) * 1996-07-08 1998-01-15 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation

Also Published As

Publication number Publication date
CO5070580A1 (es) 2001-08-28
HU229064B1 (en) 2013-07-29
DK1087750T3 (da) 2004-01-26
BG105033A (en) 2001-09-28
TW528606B (en) 2003-04-21
JP2003522102A (ja) 2003-07-22
IL140353A0 (en) 2002-02-10
BG65252B1 (bg) 2007-10-31
NO329416B1 (no) 2010-10-18
CN1161104C (zh) 2004-08-11
ATE253896T1 (de) 2003-11-15
CN1307470A (zh) 2001-08-08
NO20006318D0 (no) 2000-12-12
AU759222B2 (en) 2003-04-10
AU4552199A (en) 2000-01-05
EP1087750A1 (en) 2001-04-04
TR200003721T2 (tr) 2001-06-21
RS49977B (sr) 2008-09-29
NO20006318L (no) 2001-01-30
HRP20000867B1 (en) 2010-10-31
DE69912781T2 (de) 2004-10-21
MY121073A (en) 2005-12-30
PL345685A1 (en) 2002-01-02
CZ300910B6 (cs) 2009-09-09
KR100600423B1 (ko) 2006-07-13
KR20010072621A (ko) 2001-07-31
WO1999065464A1 (en) 1999-12-23
RU2218152C2 (ru) 2003-12-10
PL193695B1 (pl) 2007-03-30
SK19392000A3 (sk) 2001-07-10
ME00838B (me) 2008-09-29
ID27554A (id) 2001-04-12
CA2335065A1 (en) 1999-12-23
BR9911351A (pt) 2001-03-13
PT1087750E (pt) 2004-02-27
NZ509418A (en) 2003-06-30
AR019690A1 (es) 2002-03-13
EP1087750B1 (en) 2003-11-12
EE200000759A (et) 2002-04-15
HK1037974A1 (en) 2002-03-01
IL140353A (en) 2006-09-05
SK284756B6 (sk) 2005-11-03
CZ20004750A3 (en) 2001-05-16
EE04450B1 (et) 2005-04-15
HRP20000867A2 (en) 2001-10-31
CA2335065C (en) 2008-06-03
HUP0104734A2 (hu) 2002-05-29
ES2211108T3 (es) 2004-07-01
DE69912781D1 (de) 2003-12-18
HUP0104734A3 (en) 2003-05-28

Similar Documents

Publication Publication Date Title
MY121073A (en) Pharmaceutical formulations for aerosols with two or more active substances
AU4260496A (en) Propellant mixture for aerosol formulation
YU56600A (sh) Uređaj za raznošenje aktivnog agensa u pluća pacijenta
DK0771189T3 (da) Inhalationspræparat
BR9912170A (pt) Inaladores de dose medida pressurizados e formulações de aerossóis farmacêuticas
HUP0203500A2 (en) Storage system for medicaments in powder form and inhaler provided therewith
IT1317846B1 (it) Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
BR9306112A (pt) Separador para inaladores de pó
BR0309117A (pt) Kit de inalação compreendendo pó inalável de tiotropium
PT1257260E (pt) Formulacao de po
EA200100338A1 (ru) Способ и устройство для введения действующего вещества в виде аэрозоли в легкие пациента
BR9915095A (pt) Composição farmacêutica ministrável em aerosol
DE69005951D1 (de) Medikamente enthaltend Salmeterol und Fluticason.
IT1303788B1 (it) Formulazioni di aerosol medicinali.
PT1173244E (pt) Inalador de po para um medicamento combinado
FI962735A0 (fi) 2-hydroksi-5-fenylatsobensoehapon johdannaisten käyttö paksusuolen syövän kemialliseen ehkäisyyn ja kemoterapeuttisena aineena
DE69940557D1 (de) Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung
DE60031504D1 (de) Fluticasonpropionat arzneizubereitung
IL153726A0 (en) Novel aerosol formulation containing a polar fluorinated molecule
KR960702320A (ko) 감마 인터페론의 안정한 액체 조성물 (Stable Liquid Compositions of Gamma Interferon)
DE69722610D1 (de) Neue Inhalationspräparate enthaltend CR 2039 (Andolast)
PT742716E (pt) Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido
MY137747A (en) Nasal pharmaceutical piribedil composition
MY111155A (en) Medicaments
UA90346C2 (ru) Фармацевтическая рецептура для перорального приема и способ введения пациенту