BR9912170A - Inaladores de dose medida pressurizados e formulações de aerossóis farmacêuticas - Google Patents

Inaladores de dose medida pressurizados e formulações de aerossóis farmacêuticas

Info

Publication number
BR9912170A
BR9912170A BR9912170-0A BR9912170A BR9912170A BR 9912170 A BR9912170 A BR 9912170A BR 9912170 A BR9912170 A BR 9912170A BR 9912170 A BR9912170 A BR 9912170A
Authority
BR
Brazil
Prior art keywords
dose inhalers
metered dose
aerosol formulations
pressurized metered
pharmaceutical aerosol
Prior art date
Application number
BR9912170-0A
Other languages
English (en)
Inventor
Frank E Blondino
Michael Brucato
Maria W Buenafe
Original Assignee
Baker Norton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baker Norton Pharma filed Critical Baker Norton Pharma
Publication of BR9912170A publication Critical patent/BR9912170A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: "INALADORES DE DOSE MEDIDA PRESSURIZADOS E FORMULAçõES DE AEROSSóIS FARMACêUTICAS". Fornecido são inaladores de dose medida pressurizados contendo formulações estáveis de uma droga <225>-agonista em suspensão ou solução. Também fornecidos são formulações de aerossóis adequadas para terapia de inalação contendo uma droga <225>-agonista em suspensão ou solução.
BR9912170-0A 1998-06-19 1999-06-18 Inaladores de dose medida pressurizados e formulações de aerossóis farmacêuticas BR9912170A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/099,779 US6451285B2 (en) 1998-06-19 1998-06-19 Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
PCT/US1999/013863 WO1999065460A2 (en) 1998-06-19 1999-06-18 Pressurized metered dose inhalers and pharmaceutical aerosol formulations comprising a beta-agonist

Publications (1)

Publication Number Publication Date
BR9912170A true BR9912170A (pt) 2001-10-23

Family

ID=22276581

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912170-0A BR9912170A (pt) 1998-06-19 1999-06-18 Inaladores de dose medida pressurizados e formulações de aerossóis farmacêuticas

Country Status (23)

Country Link
US (2) US6451285B2 (pt)
EP (2) EP1085856B1 (pt)
JP (1) JP2002518100A (pt)
KR (1) KR20010053025A (pt)
CN (2) CN1154477C (pt)
AR (1) AR018891A1 (pt)
AT (2) ATE260093T1 (pt)
AU (1) AU762927B2 (pt)
BR (1) BR9912170A (pt)
CA (1) CA2335303A1 (pt)
CO (1) CO5031245A1 (pt)
DE (2) DE69915144T2 (pt)
DK (2) DK1085856T3 (pt)
ES (2) ES2205848T3 (pt)
HU (1) HUP0102468A3 (pt)
IL (1) IL140340A0 (pt)
NO (1) NO20006466L (pt)
PL (1) PL345399A1 (pt)
PT (2) PT1085856E (pt)
RU (1) RU2214230C2 (pt)
SK (1) SK19442000A3 (pt)
WO (1) WO1999065460A2 (pt)
ZA (1) ZA200007455B (pt)

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US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
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IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
BR0015884A (pt) 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
US20060257324A1 (en) 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
ATE375142T1 (de) * 2001-03-30 2007-10-15 Jagotec Ag Medizinische aerosolformulierungen
PT1273292E (pt) * 2001-07-02 2004-10-29 Chiesi Farma Spa Formulacao optimizada de tobramicina para aerossolizacao
US20030178022A1 (en) * 2001-12-21 2003-09-25 Chiesi Farmaceutici S.P.A. Pressurized metered dose inhaler (PMDI) actuators and medicinal aerosol solution formulation products comprising therse actuators
DE10205087A1 (de) * 2002-02-07 2003-08-21 Pharmatech Gmbh Cyclodextrine als Suspensionsstabilisatoren in druckverflüssigten Treibmitteln
PT3384931T (pt) * 2002-03-01 2019-09-26 Chiesi Farm Spa Formulaçâo superfina de formoterol
GB0207899D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and cielesonide aerosol formulations
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
ATE520405T1 (de) * 2002-08-21 2011-09-15 Norton Healthcare Ltd Inhalationszusammensetzung
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
GB0323684D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
WO2007008427A2 (en) * 2005-07-08 2007-01-18 Xemplar Pharmaceuticals, Llc Aerosol compositions and methods
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
TWI792140B (zh) * 2009-05-29 2023-02-11 美商沛爾醫療股份有限公司 用於經由呼吸道遞送二或更多種活性藥劑的組成物、方法與系統
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
EP2512438B1 (en) 2009-12-16 2017-01-25 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
GB201108039D0 (en) 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
GB201117619D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
GB201117621D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
TR201902687T4 (tr) 2013-03-15 2019-03-21 Pearl Therapeutics Inc İri parçacıklı kristal malzemelerin koşullandırılması için yöntemler ve sistemler.
GB201306984D0 (en) 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
CN108289843B (zh) 2015-12-04 2021-08-17 墨西哥氟石股份公司 药物组合物
PE20191043A1 (es) 2016-09-19 2019-08-06 Mexichem Fluor Sa De Cv Composicion farmaceutica
MX2019003105A (es) 2016-09-19 2019-08-01 Mexichem Fluor Sa De Cv Composicion farmaceutica.
CN109715148A (zh) 2016-09-19 2019-05-03 墨西哥氟石股份公司 药物组合物
CN109464429B (zh) * 2018-12-13 2021-04-27 上海方予健康医药科技有限公司 一种吸入压力定量气雾剂药物组合物及其制备方法

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Also Published As

Publication number Publication date
CO5031245A1 (es) 2001-04-27
RU2214230C2 (ru) 2003-10-20
ATE260093T1 (de) 2004-03-15
JP2002518100A (ja) 2002-06-25
KR20010053025A (ko) 2001-06-25
CA2335303A1 (en) 1999-12-23
EP1306082A1 (en) 2003-05-02
EP1085856B1 (en) 2003-09-24
ATE250409T1 (de) 2003-10-15
DE69915144D1 (de) 2004-04-01
EP1306082B1 (en) 2004-02-25
WO1999065460A2 (en) 1999-12-23
AU4825999A (en) 2000-01-05
NO20006466L (no) 2001-02-16
US6451285B2 (en) 2002-09-17
NO20006466D0 (no) 2000-12-18
AU762927B2 (en) 2003-07-10
ZA200007455B (en) 2002-06-13
US20020018753A1 (en) 2002-02-14
CN1522692A (zh) 2004-08-25
ES2215153T3 (es) 2004-10-01
HUP0102468A3 (en) 2002-12-28
DE69915144T2 (de) 2004-12-09
PT1306082E (pt) 2004-05-31
PL345399A1 (en) 2001-12-17
CN1154477C (zh) 2004-06-23
DK1306082T3 (da) 2004-06-01
PT1085856E (pt) 2004-01-30
ES2205848T3 (es) 2004-05-01
DE69911602T2 (de) 2004-07-01
IL140340A0 (en) 2002-02-10
US20030077230A1 (en) 2003-04-24
CN1310611A (zh) 2001-08-29
AR018891A1 (es) 2001-12-12
EP1085856A2 (en) 2001-03-28
DE69911602D1 (de) 2003-10-30
SK19442000A3 (sk) 2001-09-11
DK1085856T3 (da) 2003-12-08
WO1999065460A3 (en) 2000-04-27
HUP0102468A2 (hu) 2002-03-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A E 8A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1922 DE 06/11/2007.