PT1306082E - Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol - Google Patents

Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol

Info

Publication number
PT1306082E
PT1306082E PT02026980T PT02026980T PT1306082E PT 1306082 E PT1306082 E PT 1306082E PT 02026980 T PT02026980 T PT 02026980T PT 02026980 T PT02026980 T PT 02026980T PT 1306082 E PT1306082 E PT 1306082E
Authority
PT
Portugal
Prior art keywords
pressurized
pharmaceutical formulations
aerosol pharmaceutical
calibrated dose
inhibitors
Prior art date
Application number
PT02026980T
Other languages
English (en)
Inventor
Frank E Blondino
Michael Brucato
Maria W Buenafe
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Publication of PT1306082E publication Critical patent/PT1306082E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
PT02026980T 1998-06-19 1999-06-18 Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol PT1306082E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/099,779 US6451285B2 (en) 1998-06-19 1998-06-19 Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant

Publications (1)

Publication Number Publication Date
PT1306082E true PT1306082E (pt) 2004-05-31

Family

ID=22276581

Family Applications (2)

Application Number Title Priority Date Filing Date
PT99931837T PT1085856E (pt) 1998-06-19 1999-06-18 Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol compreendendo um beta-agonista
PT02026980T PT1306082E (pt) 1998-06-19 1999-06-18 Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT99931837T PT1085856E (pt) 1998-06-19 1999-06-18 Inaladores de dose calibrada pressurizada e formulacoes farmaceuticas de aerossol compreendendo um beta-agonista

Country Status (23)

Country Link
US (2) US6451285B2 (pt)
EP (2) EP1306082B1 (pt)
JP (1) JP2002518100A (pt)
KR (1) KR20010053025A (pt)
CN (2) CN1154477C (pt)
AR (1) AR018891A1 (pt)
AT (2) ATE250409T1 (pt)
AU (1) AU762927B2 (pt)
BR (1) BR9912170A (pt)
CA (1) CA2335303A1 (pt)
CO (1) CO5031245A1 (pt)
DE (2) DE69915144T2 (pt)
DK (2) DK1306082T3 (pt)
ES (2) ES2205848T3 (pt)
HU (1) HUP0102468A3 (pt)
IL (1) IL140340A0 (pt)
NO (1) NO20006466L (pt)
PL (1) PL345399A1 (pt)
PT (2) PT1085856E (pt)
RU (1) RU2214230C2 (pt)
SK (1) SK19442000A3 (pt)
WO (1) WO1999065460A2 (pt)
ZA (1) ZA200007455B (pt)

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IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
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IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
US20060257324A1 (en) 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
HU230804B1 (hu) 2000-05-22 2018-06-28 Chiesi Farmaceutici S.P.A Gyógyászati célú stabil aeroszol összetétel, inhalátor az aeroszol pontos adagolásához és eljárás ennek feltöltésére
US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
DE50211045D1 (de) * 2001-03-30 2007-11-22 Jagotec Ag Medizinische aerosolformulierungen
ATE267591T1 (de) * 2001-07-02 2004-06-15 Chiesi Farma Spa Optimierte tobramycin-formulierung zur aerosolbildung
US20030178022A1 (en) * 2001-12-21 2003-09-25 Chiesi Farmaceutici S.P.A. Pressurized metered dose inhaler (PMDI) actuators and medicinal aerosol solution formulation products comprising therse actuators
DE10205087A1 (de) * 2002-02-07 2003-08-21 Pharmatech Gmbh Cyclodextrine als Suspensionsstabilisatoren in druckverflüssigten Treibmitteln
JP2005523905A (ja) * 2002-03-01 2005-08-11 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ ホルモテロール（ｆｏｒｍｏｔｅｒｏｌ）超微細調合物
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GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
MXPA05001903A (es) * 2002-08-21 2005-04-28 Norton Healthcare Ltd Composicion para inhalacion.
GB0323684D0 (en) 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
WO2007008427A2 (en) * 2005-07-08 2007-01-18 Xemplar Pharmaceuticals, Llc Aerosol compositions and methods
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
US9463161B2 (en) * 2009-05-29 2016-10-11 Pearl Therapeutics, Inc. Compositions for pulmonary delivery of long-acting muscarinic antagonists and associated methods and systems
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
US20120272951A1 (en) 2009-12-16 2012-11-01 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
GB201108039D0 (en) 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
GB201117619D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
GB201117621D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス，インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
GB201306984D0 (en) 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
EP3383366B1 (en) 2015-12-04 2020-03-25 Mexichem Fluor S.A. de C.V. Pharmaceutical composition
CN109715148A (zh) 2016-09-19 2019-05-03 墨西哥氟石股份公司 药物组合物
CN113288869A (zh) 2016-09-19 2021-08-24 墨西哥氟石股份公司 药物组合物
CN114515284A (zh) 2016-09-19 2022-05-20 墨西哥氟石股份公司 药物组合物
CN109464429B (zh) * 2018-12-13 2021-04-27 上海方予健康医药科技有限公司 一种吸入压力定量气雾剂药物组合物及其制备方法

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NZ298169A (en) 1994-12-22 1999-09-29 Astra Ab Aerosol drug formulation; comprises hydrofluoroalkane propellant, medicament for inhalation and a surfactant
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GB9612297D0 (en) 1996-06-11 1996-08-14 Minnesota Mining & Mfg Medicinal aerosol formulations
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US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
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Also Published As

Publication number Publication date
KR20010053025A (ko) 2001-06-25
DK1306082T3 (da) 2004-06-01
NO20006466L (no) 2001-02-16
BR9912170A (pt) 2001-10-23
EP1085856A2 (en) 2001-03-28
JP2002518100A (ja) 2002-06-25
DE69911602D1 (de) 2003-10-30
DK1085856T3 (da) 2003-12-08
WO1999065460A3 (en) 2000-04-27
CN1522692A (zh) 2004-08-25
ES2215153T3 (es) 2004-10-01
HUP0102468A3 (en) 2002-12-28
DE69915144D1 (de) 2004-04-01
HUP0102468A2 (hu) 2002-03-28
AU762927B2 (en) 2003-07-10
US20020018753A1 (en) 2002-02-14
CN1154477C (zh) 2004-06-23
CA2335303A1 (en) 1999-12-23
DE69915144T2 (de) 2004-12-09
CO5031245A1 (es) 2001-04-27
AU4825999A (en) 2000-01-05
EP1085856B1 (en) 2003-09-24
ATE260093T1 (de) 2004-03-15
ZA200007455B (en) 2002-06-13
SK19442000A3 (sk) 2001-09-11
ATE250409T1 (de) 2003-10-15
US20030077230A1 (en) 2003-04-24
AR018891A1 (es) 2001-12-12
EP1306082B1 (en) 2004-02-25
IL140340A0 (en) 2002-02-10
RU2214230C2 (ru) 2003-10-20
PL345399A1 (en) 2001-12-17
DE69911602T2 (de) 2004-07-01
CN1310611A (zh) 2001-08-29
ES2205848T3 (es) 2004-05-01
EP1306082A1 (en) 2003-05-02
WO1999065460A2 (en) 1999-12-23
NO20006466D0 (no) 2000-12-18
PT1085856E (pt) 2004-01-30
US6451285B2 (en) 2002-09-17

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