PT742716E - Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido - Google Patents

Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido

Info

Publication number
PT742716E
PT742716E PT95905121T PT95905121T PT742716E PT 742716 E PT742716 E PT 742716E PT 95905121 T PT95905121 T PT 95905121T PT 95905121 T PT95905121 T PT 95905121T PT 742716 E PT742716 E PT 742716E
Authority
PT
Portugal
Prior art keywords
glucuronide
pharmaceutical composition
systemic
morfine
administration containing
Prior art date
Application number
PT95905121T
Other languages
English (en)
Inventor
Thomas Hille
Karlheinz Otto
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of PT742716E publication Critical patent/PT742716E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
PT95905121T 1994-02-07 1995-01-05 Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido PT742716E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4403709A DE4403709A1 (de) 1994-02-07 1994-02-07 Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid

Publications (1)

Publication Number Publication Date
PT742716E true PT742716E (pt) 2003-07-31

Family

ID=6509638

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95905121T PT742716E (pt) 1994-02-07 1995-01-05 Composicao farmaceutica para administracao transdermica sistemica contendo a substancia activa morfina-6-glucuronido

Country Status (10)

Country Link
US (1) US5705186A (pt)
EP (1) EP0742716B1 (pt)
JP (1) JP3980634B2 (pt)
AT (1) ATE234096T1 (pt)
CA (1) CA2182812C (pt)
DE (2) DE4403709A1 (pt)
DK (1) DK0742716T3 (pt)
ES (1) ES2194899T3 (pt)
PT (1) PT742716E (pt)
WO (1) WO1995020966A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2201482T3 (es) * 1997-04-14 2004-03-16 Ufc Limited Derivados de la morfina.
DE19901085C2 (de) * 1999-01-14 2003-12-18 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit einer selbstklebenden Matrix, enthaltend organische Säure-Additionssalze von Alkaloiden des Morphin- bzw. Morphinantyps
GB0218811D0 (en) * 2002-08-14 2002-09-18 Cenes Ltd Salts of morphine-6-glucuronide
JP5927506B2 (ja) 2010-04-13 2016-06-01 レルマダ セラピューティクス、インク. 1−メチル−2’,6’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
CN107028968B (zh) * 2016-02-03 2020-12-04 江苏恒瑞医药股份有限公司 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物
JP6982960B2 (ja) * 2017-02-07 2021-12-17 リンテック株式会社 包材および包装体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
DE3315272C2 (de) * 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
US4806341A (en) * 1985-02-25 1989-02-21 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
SE9003665D0 (sv) * 1990-11-16 1990-11-16 Kabivitrum Ab Morphine prodrugs
GB9116909D0 (en) * 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.
GB9202464D0 (en) * 1992-02-05 1992-03-18 Danbiosyst Uk Composition for nasal administration
GB2282758A (en) * 1993-08-23 1995-04-19 Euro Celtique Sa Oral morphine-6-glucuronide compositions

Also Published As

Publication number Publication date
ATE234096T1 (de) 2003-03-15
EP0742716A1 (de) 1996-11-20
ES2194899T3 (es) 2003-12-01
JP3980634B2 (ja) 2007-09-26
WO1995020966A1 (de) 1995-08-10
US5705186A (en) 1998-01-06
DK0742716T3 (da) 2003-06-16
DE59510583D1 (de) 2003-04-17
CA2182812C (en) 2006-07-25
JPH09509154A (ja) 1997-09-16
DE4403709A1 (de) 1995-08-10
CA2182812A1 (en) 1995-08-10
EP0742716B1 (de) 2003-03-12

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