MX2021011081A - Derivados de nicorandil. - Google Patents

Derivados de nicorandil.

Info

Publication number
MX2021011081A
MX2021011081A MX2021011081A MX2021011081A MX2021011081A MX 2021011081 A MX2021011081 A MX 2021011081A MX 2021011081 A MX2021011081 A MX 2021011081A MX 2021011081 A MX2021011081 A MX 2021011081A MX 2021011081 A MX2021011081 A MX 2021011081A
Authority
MX
Mexico
Prior art keywords
nicorandil
compounds
derivatives
disclosed
kidney
Prior art date
Application number
MX2021011081A
Other languages
English (en)
Inventor
Shalabh Gupta
Sundeep Dugar
Original Assignee
Unicycive Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unicycive Therapeutics Inc filed Critical Unicycive Therapeutics Inc
Publication of MX2021011081A publication Critical patent/MX2021011081A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425—Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

En el presente documento se describen compuestos de piridilo. También se describen compuestos de nicorandil 5 conjugados específicos. También se describen composiciones farmacéuticas que incluyen los compuestos. Se describen métodos para usar los compuestos de piridilo para el tratamiento de enfermedades o afecciones relacionadas con el riñón o las funciones del riñón.
MX2021011081A 2019-03-15 2020-03-16 Derivados de nicorandil. MX2021011081A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962819372P 2019-03-15 2019-03-15
PCT/US2020/023016 WO2020190890A1 (en) 2019-03-15 2020-03-16 Nicorandil derivatives

Publications (1)

Publication Number Publication Date
MX2021011081A true MX2021011081A (es) 2022-01-18

Family

ID=70296016

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021011081A MX2021011081A (es) 2019-03-15 2020-03-16 Derivados de nicorandil.

Country Status (12)

Country Link
US (3) US20220265630A1 (es)
EP (1) EP3937938A1 (es)
JP (1) JP2022524243A (es)
KR (1) KR20220009373A (es)
CN (1) CN114144178A (es)
AU (1) AU2020240015A1 (es)
BR (1) BR112021018254A2 (es)
CA (1) CA3133093A1 (es)
IL (1) IL286434A (es)
MX (1) MX2021011081A (es)
SG (1) SG11202109899VA (es)
WO (1) WO2020190890A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4370121A1 (en) 2021-07-10 2024-05-22 Auxilius Pharma Spolka Z Ograniczona Odpowiedzialnoscia Modified release nicorandil compound formulations
WO2024151489A1 (en) 2023-01-09 2024-07-18 Unicycive Therapeutics Inc. Pharmaceutical pyridyl compositions and methods for use

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Also Published As

Publication number Publication date
IL286434A (en) 2021-10-31
US20220265630A1 (en) 2022-08-25
SG11202109899VA (en) 2021-10-28
CA3133093A1 (en) 2020-09-24
AU2020240015A1 (en) 2021-10-07
BR112021018254A8 (pt) 2021-11-23
CN114144178A (zh) 2022-03-04
BR112021018254A2 (pt) 2022-03-15
EP3937938A1 (en) 2022-01-19
JP2022524243A (ja) 2022-04-28
WO2020190890A8 (en) 2021-09-10
US12036211B2 (en) 2024-07-16
KR20220009373A (ko) 2022-01-24
US20220079927A1 (en) 2022-03-17
US20230310398A1 (en) 2023-10-05
WO2020190890A1 (en) 2020-09-24

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