JP2022502490A5 - - Google Patents

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Publication number
JP2022502490A5
JP2022502490A5 JP2021540378A JP2021540378A JP2022502490A5 JP 2022502490 A5 JP2022502490 A5 JP 2022502490A5 JP 2021540378 A JP2021540378 A JP 2021540378A JP 2021540378 A JP2021540378 A JP 2021540378A JP 2022502490 A5 JP2022502490 A5 JP 2022502490A5
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alkyl
alkylene
cycloalkyl
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JP2021540378A
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JP2022502490A (ja
JP7399968B2 (ja
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Priority claimed from PCT/US2019/052567 external-priority patent/WO2020068729A1/en
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JP2021540378A 2018-09-25 2019-09-24 Alk2及び/またはfgfr調節剤としてのピラゾロ[4,3-d]ピリミジン化合物 Active JP7399968B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862736121P 2018-09-25 2018-09-25
US62/736,121 2018-09-25
PCT/US2019/052567 WO2020068729A1 (en) 2018-09-25 2019-09-24 Pyrazolo[4,3-d]pyrimidine compounds as alk2 abd/or fgfr modulators

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JP2022502490A JP2022502490A (ja) 2022-01-11
JP2022502490A5 true JP2022502490A5 (https=) 2022-06-06
JP7399968B2 JP7399968B2 (ja) 2023-12-18

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JP2021540378A Active JP7399968B2 (ja) 2018-09-25 2019-09-24 Alk2及び/またはfgfr調節剤としてのピラゾロ[4,3-d]ピリミジン化合物

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US (2) US11111247B2 (https=)
EP (1) EP3856348B1 (https=)
JP (1) JP7399968B2 (https=)
AR (1) AR116507A1 (https=)
ES (1) ES2973117T3 (https=)
MA (1) MA53726A (https=)
TW (1) TW202028207A (https=)
WO (1) WO2020068729A1 (https=)

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US12508262B2 (en) 2020-04-30 2025-12-30 Keros Therapeutics, Inc. Methods of using ALK2 inhibitors
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
WO2022098812A1 (en) 2020-11-04 2022-05-12 Keros Therapeutics, Inc. Methods of treating iron overload
CN114790205A (zh) * 2021-01-26 2022-07-26 江苏恒瑞医药股份有限公司 氘代吡唑并吡啶类化合物、其制备方法及其在医药上的应用
CN112941036B (zh) * 2021-02-08 2023-06-09 吉林惠康生物药业有限公司 一种提高狂犬病毒在人二倍体细胞中复制水平的方法
WO2022199652A1 (en) * 2021-03-24 2022-09-29 Impact Therapeutics (Shanghai) , Inc Five-membered heteroaryl-pyrimidine compounds as usp1 inhibitors and the use thereof
CN116925098B (zh) * 2022-04-09 2026-02-17 深圳湾实验室 靶向泛素特异性蛋白酶1(usp1)的小分子抑制剂及其应用
WO2024022519A1 (zh) * 2022-07-28 2024-02-01 先声再明医药有限公司 杂环并嘧啶类化合物及其应用

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