JP2022174292A5 - - Google Patents

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Publication number
JP2022174292A5
JP2022174292A5 JP2022150051A JP2022150051A JP2022174292A5 JP 2022174292 A5 JP2022174292 A5 JP 2022174292A5 JP 2022150051 A JP2022150051 A JP 2022150051A JP 2022150051 A JP2022150051 A JP 2022150051A JP 2022174292 A5 JP2022174292 A5 JP 2022174292A5
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composition
weight
composition according
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sildenafil
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JP2022150051A
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JP7459200B2 (ja
JP2022174292A (ja
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Priority claimed from JP2020196696A external-priority patent/JP7187522B2/ja
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Priority to JP2024043773A priority Critical patent/JP2024073624A/ja
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Publication of JP7459200B2 publication Critical patent/JP7459200B2/ja
Priority to JP2025166527A priority patent/JP2025183462A/ja
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JP2022150051A 2010-12-29 2022-09-21 勃起不全および他の適応症の処置 Active JP7459200B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024043773A JP2024073624A (ja) 2010-12-29 2024-03-19 勃起不全および他の適応症の処置
JP2025166527A JP2025183462A (ja) 2010-12-29 2025-10-02 勃起不全および他の適応症の処置

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061427999P 2010-12-29 2010-12-29
US201061428213P 2010-12-29 2010-12-29
US61/427,999 2010-12-29
US61/428,213 2010-12-29
JP2020196696A JP7187522B2 (ja) 2010-12-29 2020-11-27 勃起不全および他の適応症の処置

Related Parent Applications (1)

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JP2020196696A Division JP7187522B2 (ja) 2010-12-29 2020-11-27 勃起不全および他の適応症の処置

Related Child Applications (1)

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JP2024043773A Division JP2024073624A (ja) 2010-12-29 2024-03-19 勃起不全および他の適応症の処置

Publications (3)

Publication Number Publication Date
JP2022174292A JP2022174292A (ja) 2022-11-22
JP2022174292A5 true JP2022174292A5 (enExample) 2023-06-21
JP7459200B2 JP7459200B2 (ja) 2024-04-01

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Family Applications (8)

Application Number Title Priority Date Filing Date
JP2013547687A Withdrawn JP2014504592A (ja) 2010-12-29 2011-12-29 勃起不全および他の適応症の処置
JP2016087702A Active JP6283392B2 (ja) 2010-12-29 2016-04-26 勃起不全および他の適応症の処置
JP2018011735A Active JP6533840B2 (ja) 2010-12-29 2018-01-26 勃起不全および他の適応症の処置
JP2019098658A Active JP6802879B2 (ja) 2010-12-29 2019-05-27 勃起不全および他の適応症の処置
JP2020196696A Active JP7187522B2 (ja) 2010-12-29 2020-11-27 勃起不全および他の適応症の処置
JP2022150051A Active JP7459200B2 (ja) 2010-12-29 2022-09-21 勃起不全および他の適応症の処置
JP2024043773A Pending JP2024073624A (ja) 2010-12-29 2024-03-19 勃起不全および他の適応症の処置
JP2025166527A Pending JP2025183462A (ja) 2010-12-29 2025-10-02 勃起不全および他の適応症の処置

Family Applications Before (5)

Application Number Title Priority Date Filing Date
JP2013547687A Withdrawn JP2014504592A (ja) 2010-12-29 2011-12-29 勃起不全および他の適応症の処置
JP2016087702A Active JP6283392B2 (ja) 2010-12-29 2016-04-26 勃起不全および他の適応症の処置
JP2018011735A Active JP6533840B2 (ja) 2010-12-29 2018-01-26 勃起不全および他の適応症の処置
JP2019098658A Active JP6802879B2 (ja) 2010-12-29 2019-05-27 勃起不全および他の適応症の処置
JP2020196696A Active JP7187522B2 (ja) 2010-12-29 2020-11-27 勃起不全および他の適応症の処置

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024043773A Pending JP2024073624A (ja) 2010-12-29 2024-03-19 勃起不全および他の適応症の処置
JP2025166527A Pending JP2025183462A (ja) 2010-12-29 2025-10-02 勃起不全および他の適応症の処置

Country Status (10)

Country Link
US (10) US9463158B2 (enExample)
EP (3) EP3721893B1 (enExample)
JP (8) JP2014504592A (enExample)
CN (3) CN103429247A (enExample)
DK (1) DK2658551T3 (enExample)
ES (2) ES3011984T3 (enExample)
HR (1) HRP20201512T1 (enExample)
HU (1) HUE050862T2 (enExample)
PT (1) PT2658551T (enExample)
WO (1) WO2012092528A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
AU2005235309B2 (en) * 2004-04-19 2012-07-26 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US12138268B2 (en) 2009-06-24 2024-11-12 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
AU2009348470B2 (en) 2009-06-24 2015-04-02 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
WO2010151241A1 (en) 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
US9289495B2 (en) 2010-12-29 2016-03-22 Strategic Science & Technologies, Llc Systems and methods for treatment of allergies and other indications
CN103429247A (zh) 2010-12-29 2013-12-04 战略科学与技术有限责任公司 勃起功能障碍和其它适应症的治疗
CN105377233A (zh) * 2013-03-15 2016-03-02 战略科学与技术有限责任公司 氟替卡松的透皮制剂
EP2968130A1 (en) 2013-03-15 2016-01-20 Strategic Science & Technologies, LLC Transdermal delivery of sildenafil and other phosphodiesterase type 5 inhibitors
US20180078602A1 (en) * 2015-03-04 2018-03-22 K.L.R.M., Llc Methods and compositions for extending the efficacy of phosphodiesterase inhibitors for treating erectile dysfunction, and compositions for inhibiting the onset and slowing the progression of erectile dysfunction
EP3468530A4 (en) 2016-06-10 2020-03-11 Clarity Cosmetics Inc. NON-COMEDOGEN FORMULA FOR HAIR AND SCALP CARE AND METHOD FOR USE
CN107296789A (zh) * 2017-07-08 2017-10-27 天津双硕医药科技有限公司 一种含有枸橼酸西地那非的外用药物组合物
CA3082286A1 (en) * 2017-12-04 2019-06-13 Johnson & Johnson Consumer Inc. Topical emulsion composition containing nonsteroidal anti-inflammatory drug
WO2021236891A1 (en) * 2020-05-20 2021-11-25 Augusta University Research Institute, Inc. Gut-targeted phosphodiesterase inhibitors
AU2021373070B2 (en) 2020-11-09 2023-08-24 Albert Einstein College Of Medicine Transdermal delivery formulations
US12059493B2 (en) 2020-11-09 2024-08-13 Albert Einstein College Of Medicine Transdermal delivery formulations
US12151019B2 (en) 2020-11-09 2024-11-26 Albert Einstein College Of Medicine Compositions for blood storage and transfusions
CN120981235A (zh) * 2023-02-14 2025-11-18 戴尔生物科学公司 治疗女性性功能障碍和女性性唤起障碍的组合物和方法

Family Cites Families (222)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5940E (fr) 1906-01-30 1906-07-27 Ramier Et Mauberque Soc Radiateur
FR5799M (enExample) 1966-03-22 1968-03-25
FR5940M (enExample) 1966-10-18 1968-04-08
FR1553063A (enExample) 1967-11-28 1969-01-10
US3960782A (en) 1974-09-27 1976-06-01 The Procter & Gamble Company Shampoo compositions which impart high luster and manageability to hair
US4185100A (en) 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
JPS5753404A (en) 1980-09-17 1982-03-30 Kao Corp External preparation for skin obtained by blending plant extract
GB2094142B (en) 1981-03-06 1984-09-26 Lab For Applied Biology Ltd Injectable solution containing theophylline and a basic amino acid
GB2126868B (en) 1982-09-20 1986-03-19 Ralston Purina Co Method of improving the shelf life of processed meat products
DE3327840C1 (de) 1983-08-02 1984-09-20 Blendax Werke Schneider Co Hautpflegemittel
FR2557452B1 (fr) 1983-12-28 1986-08-14 Roussel Uclaf Nouvelles compositions pour les soins de la peau renfermant de l'huile d'onagre et des traits tissulaires de rate
US4681897A (en) 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US4722837A (en) 1984-05-29 1988-02-02 Derma-Cure, Inc. Medicated shampoo composition
JPS60252412A (ja) 1984-05-29 1985-12-13 Nichiban Co Ltd 貼布治療製剤
US4692462A (en) 1985-03-18 1987-09-08 Menley & James Laboratories, Ltd. Compositions and method of controlling transdermal penetration of topical and systemic agents
US4732892A (en) 1985-07-12 1988-03-22 American Home Products Corporation L-α-amino acids as transdermal penetration enhancers
DE3684564D1 (de) 1985-11-18 1992-04-30 Beecham Group Plc Veterinaere zusammensetzungen.
GB8606368D0 (en) 1986-03-14 1986-04-23 Unilever Plc Skin treatment composition
FR2602678B1 (fr) 1986-08-13 1992-06-05 Drouault Guy Composition pharmaceutique aqueuse a base de sels de magnesium, sodium et potassium pour la regulation des circulations locales
US4940456A (en) 1987-02-10 1990-07-10 Dan Sibalis Electrolytic transdermal delivery of proteins
US4885157A (en) 1987-02-13 1989-12-05 Fiaschetti Mary G Dermal cosmetic composition and applications therefor
DE3715576A1 (de) 1987-05-09 1988-11-24 Wella Ag Neue makromolekulare, oberflaechenaktive, quaternaere n-substituierte chitosanderivate sowie kosmetisches mittel auf der basis dieser neuen chitosanderivate
KR900004875Y1 (ko) 1987-10-02 1990-05-31 삼성전자 주식회사 Pip의 수평 윈도우 신호발생 회로
US5925372A (en) 1987-12-16 1999-07-20 Novartis Corporation Mixed solvent mutually enhanced transdermal therapeutic system
JPH045231Y2 (enExample) 1987-12-16 1992-02-14
US4871718A (en) 1987-12-29 1989-10-03 Raymond A. Roncari Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair
GB2217595B (en) 1988-04-21 1991-11-20 American Cyanamid Co Antiinflammatory gel
DE3827362A1 (de) 1988-08-12 1990-02-15 Basf Ag Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung
AU4345489A (en) 1988-09-30 1990-04-18 Duane R. Schultz Anti-inflammatory and analgesic compounds, related compositions and methods for preparation and use thereof
WO1990008553A1 (en) 1989-01-24 1990-08-09 Abbott Laboratories Transdermal drug delivery composition
US4945901A (en) 1989-03-22 1990-08-07 Burcke Jr Harry J Hand therapy apparatus and method therefor
US5158761A (en) 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
US5476852A (en) 1989-05-03 1995-12-19 Janssen Pharmaceutica N.V. Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
US5028435A (en) 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
JP2761939B2 (ja) 1989-09-04 1998-06-04 株式会社コーセー 水中油型乳化化粧料
PT95564B (pt) 1989-10-17 1997-11-28 Merck & Co Inc Processo para a preparacao de (+)-ibuprofen-d-aminoacido uteis como analgesicos intensificados de ataque acelerado
US5576351A (en) 1989-12-29 1996-11-19 Mcgaw, Inc. Use of arginine as an immunostimulator
EP0441119A3 (en) 1990-01-09 1992-10-14 Richard D. Levere The use of l-arginine in the treatment of hypertension and other vascular disorders
JPH045231A (ja) 1990-04-20 1992-01-09 Morishita Pharmaceut Co Ltd 慢性痛用鎮痛剤
US5332758A (en) 1990-07-13 1994-07-26 Kanebo, Ltd. Collagen metabolism ameliorant and its use
US5824658A (en) 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
ES2070513T3 (es) 1990-11-14 1995-06-01 Upjohn Co Compuestos de 5-fluoro-2,4,6-pirimidintriamina para prevenir la caida del pelo.
DE4100975A1 (de) 1991-01-15 1992-07-16 Weuffen Wolfgang Kosmetische oder pharmazeutische zubereitungen zur verbesserung der haarqualitaet und foerderung des haarwachstums
US5210099A (en) 1991-02-11 1993-05-11 American Home Products Corporation Analgesic compositions
ATE157009T1 (de) 1991-03-01 1997-09-15 Atherton Investments Ltd Therapeutische und kosmetische zusammensetzungen zur hautbehandlung
AU1454592A (en) 1991-03-01 1992-10-06 Bellavista Enterprises, Inc. Therapeutic and cosmetic compositions for treatment of skin
US5498420A (en) 1991-04-12 1996-03-12 Merz & Co. Gmbh & Co. Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions
EP0515982B1 (en) 1991-05-27 1995-04-19 Fujisawa Pharmaceutical Co., Ltd. Normal-pentadecyl nicotinate N-oxide and hair restorer comprising the same
JP2636118B2 (ja) 1991-09-10 1997-07-30 三省製薬株式会社 育毛剤
US5254331A (en) 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
US5215759A (en) 1991-10-01 1993-06-01 Chanel, Inc. Cosmetic composition
US5217652A (en) 1991-10-04 1993-06-08 The Gillette Company Conditioning shampoo
IT1252061B (it) 1991-11-22 1995-05-29 Gentili Ist Spa Composizioni per uso dermatologico e cosmetico
DE69320378T2 (de) 1992-01-21 1999-04-29 Macrochem Corp Iontophoretische verbesserte Verabreichung von Medikamenten
JP3302995B2 (ja) 1992-04-01 2002-07-15 株式会社ダイゾー エアゾール組成物
US5632981A (en) 1992-08-24 1997-05-27 The United States Of America As Represented By The Department Of Health And Human Services Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
US5405919A (en) 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5691423A (en) 1992-08-24 1997-11-25 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-bound nitric oxide-nucleophile adducts
WO1994006141A1 (fr) 1992-08-31 1994-03-17 Idec Izumi Corporation Ensemble interrupteur de securite
DK169121B1 (da) 1992-09-09 1994-08-22 Gea Farmaceutisk Fabrik As Antiviralt virksom farmaceutisk olie-i-vand-emulsion indeholdende 9-[(2-hydroxyethoxy)methyl]guanin (acyclovir) eller et salt eller en ester deraf
GB9222772D0 (en) 1992-10-30 1992-12-09 Unilever Plc Cosmetic composition
US5573776A (en) 1992-12-02 1996-11-12 Alza Corporation Oral osmotic device with hydrogel driving member
JP3191833B2 (ja) 1993-02-24 2001-07-23 三菱東京製薬株式会社 育毛剤
JPH06287135A (ja) 1993-04-01 1994-10-11 Lion Corp 皮膚外用剤組成物
US5439938A (en) 1993-04-07 1995-08-08 The Johns Hopkins University Treatments for male sexual dysfunction
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
US5428070A (en) 1993-06-11 1995-06-27 The Board Of Trustees Of The Leland Stanford Junior University Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production of activity
US5891459A (en) 1993-06-11 1999-04-06 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
US5852058A (en) 1993-06-11 1998-12-22 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
JP3200723B2 (ja) 1993-08-18 2001-08-20 日本農薬株式会社 育毛剤
DE4338793A1 (de) 1993-11-12 1995-05-18 Froelich Juergen C L-Arginin und Analoge als Thrombozytenaggregationshemmer
DE4341000A1 (de) 1993-12-02 1995-06-08 Beiersdorf Ag Verwendung von L-Arginin, L-Ornithin oder L-Citrullin und topischen Zubereitungen mit diesen Stoffen
US5714472A (en) 1993-12-23 1998-02-03 Nestec Ltd. Enternal formulation designed for optimized nutrient absorption and wound healing
GB9409281D0 (en) 1994-05-10 1994-06-29 Svedman Paul Transdermal device
JPH07316075A (ja) 1994-05-26 1995-12-05 Pola Chem Ind Inc 皮膚外用剤
JP3211892B2 (ja) 1994-05-27 2001-09-25 セイジィ ファーマスーティカルス インコーポレーテッド 肛門疾患を治療する窒素酸化物供与体及び方法
US6190704B1 (en) 1994-09-23 2001-02-20 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Regulation of wound healing by nitric oxide
US5543430A (en) 1994-10-05 1996-08-06 Kaesemeyer; W. H. Method and formulation of stimulating nitric oxide synthesis
US5505958A (en) 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
AU690377B2 (en) 1994-11-04 1998-04-23 Polymun Scientific Immunobiologische Forschung Gmbh Application of superoxide dismutase in liposomes
US5594032A (en) 1994-11-10 1997-01-14 Gonzalez-Cadavid; Nestor F. Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA
US5648101A (en) 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
US5562917A (en) 1994-12-23 1996-10-08 Pentech Pharmaceuticals, Inc. Transdermal administration of apomorphine
US5853768A (en) 1995-03-01 1998-12-29 Altadonna; James Topical preparation and method for pain relief
US5654337A (en) 1995-03-24 1997-08-05 II William Scott Snyder Topical formulation for local delivery of a pharmaceutically active agent
US5595753A (en) 1995-04-14 1997-01-21 President And Fellows Of Harvard College Topical formulations and methods for treating hemorrhoidal pain and sphincter and smooth muscle spasm in the gastrointestinal tract
US5643586A (en) 1995-04-27 1997-07-01 Perricone; Nicholas V. Topical compositions and methods for treatment of skin damage and aging using catecholamines and related compounds
US5698738A (en) 1995-05-15 1997-12-16 Board Of Regents, The University Of Texas System N-nitroso-N-substituted hydroxylamines as nitric oxide donors
US5762963A (en) 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
US5645859A (en) 1995-10-02 1997-07-08 Isp Investments Inc. Process for producing an alpha or beta-hydroxy acid-vinylpyrrolidone polymer, copolymer or graft polymer complex in the form of free-flowing powders having a high acid loading
US5605685A (en) 1995-09-13 1997-02-25 Isp Investments Inc. Non-irritating skin and hair rejuvenating compostion having a pH between 1 and 6.5
US5734080A (en) 1995-09-22 1998-03-31 Anihealth Corporation Reaction product of arginine and p-aminobenzoic acid, cosmetic, and human and animal health compositions thereof
US6036977A (en) 1995-09-29 2000-03-14 L.A.M. Pharmaceutical Corp. Drug preparations for treating sexual dysfunction
FR2740339B1 (fr) 1995-10-26 1997-12-05 Oreal Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles
FR2740453B1 (fr) 1995-10-27 1998-01-16 Bieurope Melanges peptidiques, leur preparation et compositions cosmetiques les contenant
JP2681881B2 (ja) 1995-11-24 1997-11-26 ナショナル サイエンス カウンシル 抗ウイルス剤アシクロビルの経皮吸収製剤
US5789442A (en) 1996-01-18 1998-08-04 Schering Aktiengesellschaft Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents
JPH09208460A (ja) 1996-01-31 1997-08-12 Lion Corp 貼付剤
JP4020989B2 (ja) 1996-03-06 2007-12-12 株式会社ノエビア 血流促進剤及びこれを配合して成る皮膚外用剤
GB9608408D0 (en) 1996-04-23 1996-06-26 Adams Michael A Treatment of erectile dysfunction
US5911980A (en) 1996-06-27 1999-06-15 Macrochem Corporation Lipophilic and amphiphilic or hydrophilic film-forming polymer compositions, and use thereof in topical agent delivery system and method of delivering agents to the skin
US5985317A (en) 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
US20020015713A1 (en) 1996-10-24 2002-02-07 Murdock Robert W. Methods and transdermal compositions for pain relief
US5891472A (en) 1996-11-19 1999-04-06 Meri Charmyne Russell Treatment of equine laminitis
JPH10167953A (ja) 1996-12-06 1998-06-23 Daicel Chem Ind Ltd 化粧品組成物
US5807957A (en) 1996-12-23 1998-09-15 Macrochem Corporation Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering agents to the skin
IL120531A (en) 1997-03-26 2006-12-31 Yissum Res Dev Co Nitric oxide donors and pharmaceutical compositions containing them
FR2762782B1 (fr) 1997-05-05 1999-06-11 Oreal Composition comprenant un milieu de culture de micro-organisme et utilisation
WO1999001427A2 (en) 1997-07-03 1999-01-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services, National Institutes Of Health Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
US5976566A (en) 1997-08-29 1999-11-02 Macrochem Corporation Non-steroidal antiinflammtory drug formulations for topical application to the skin
US7914814B2 (en) 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US5922332A (en) 1997-09-17 1999-07-13 Fossel; Eric T. Topical delivery of arginine to overcome pain
WO1999013717A1 (en) 1997-09-17 1999-03-25 Strategic Science & Technologies, Inc. A delivery of arginine to cause beneficial effects
US7629384B2 (en) 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US6207713B1 (en) 1997-09-17 2001-03-27 Eric T. Fossel Topical and oral delivery of arginine to cause beneficial effects
US5895658A (en) 1997-09-17 1999-04-20 Fossel; Eric T. Topical delivery of L-arginine to cause tissue warming
US6096759A (en) 1997-09-19 2000-08-01 Georgetown University Method for treating essential hypertension
US5906822A (en) 1997-09-25 1999-05-25 Macrochem Corporation Cationic film-forming polymer compositions, and use thereof in topical agents delivery system and method of delivering agents to the skin
US6037346A (en) 1997-10-28 2000-03-14 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US6548490B1 (en) 1997-10-28 2003-04-15 Vivus, Inc. Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US20040014761A1 (en) 1997-10-28 2004-01-22 Place Virgil A. Treatment of female sexual dysfunction with phosphodiesterase inhibitors
US6046244A (en) 1997-11-05 2000-04-04 Nexmed Holdings, Inc. Topical compositions for prostaglandin E1 delivery
GB9801398D0 (en) 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
CA2333903A1 (en) 1998-06-01 1999-12-09 Anthony J. Verbiscar Topical transdermal treatments
US6103275A (en) 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
US6117872A (en) 1998-06-23 2000-09-12 The Board Of Trustees Of The Leland Stanford Junior University Enhancement of exercise performance by augmenting endogenous nitric oxide production or activity
PT1094781E (pt) 1998-07-07 2008-10-08 Transdermal Technologies Inc Composições para administração transdérmica rápida e não irritante de agentes farmacologicamente activos e métodos para formulação de tais composições e sua administração
DE19830649C2 (de) 1998-07-09 2003-04-10 Lohmann Therapie Syst Lts Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe
DE19831798A1 (de) 1998-07-15 2000-01-27 Mandorlo Investment Gmbh Luxem Mittel zur Pflege und/oder Behandlung von Haut und Gewebe
CA2347979C (en) 1998-10-26 2009-01-06 University Of Massachusetts Treatment of skin with adenosine or adenosine analog
US6261594B1 (en) 1998-11-25 2001-07-17 The University Of Akron Chitosan-based nitric oxide donor compositions
JP2000186028A (ja) 1998-12-21 2000-07-04 Nobuko Koga 化粧品
FR2787996B1 (fr) 1998-12-30 2002-05-10 Dior Christian Parfums Composition cosmetique ou dermatologique contenant un actif stimulant la synthese de la proteine hsp 32 dans la peau et methode de traitement cosmetique
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
WO2000054773A1 (en) 1999-03-12 2000-09-21 Nitromed, Inc. Dopamine agonists in combination with nitric oxide donors, compositions and methods of use
US6387081B1 (en) 1999-03-12 2002-05-14 Mystic Tan, Inc. Misting apparatus for application of coating materials to skin surface
US6375672B1 (en) 1999-03-22 2002-04-23 Board Of Trustees Of Michigan State University Method for controlling the chemical and heat induced responses of collagenous materials
FR2794974B1 (fr) 1999-06-16 2001-08-17 Exsymol Sa Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique
CN1406123B (zh) 1999-09-07 2010-04-21 株式会社创研 皮肤健全化剂
US6565879B1 (en) 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US6558695B2 (en) 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US6562370B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
US6586000B2 (en) 1999-12-16 2003-07-01 Dermatrends, Inc. Hydroxide-releasing agents as skin permeation enhancers
US6719997B2 (en) 2000-06-30 2004-04-13 Dermatrends, Inc. Transdermal administration of pharmacologically active amines using hydroxide-releasing agents as permeation enhancers
US6602912B2 (en) 2000-06-30 2003-08-05 Dermatrends, Inc. Transdermal administration of phenylpropanolamine
US6582724B2 (en) 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
FR2802414B1 (fr) 1999-12-20 2003-06-27 G Pharm Lab Composition, notamment cosmetique ou dermatologique, contenant des oligosaccharides, son procede de preparation et un procede de traitement cosmetique
DE10003767A1 (de) 2000-01-28 2001-10-04 Beiersdorf Ag Hautfreundliches Wirkstoffpflaster zur transdermalen Verabreichung nichtsteroidaler Antirheumatika
JP2001288068A (ja) 2000-04-06 2001-10-16 Nof Corp 皮膚化粧料
FR2810540B1 (fr) 2000-06-21 2004-04-30 C3D Nouvelles preparations cosmetiques ou hygieniques sous forme de dispersion
JP2002003373A (ja) 2000-06-27 2002-01-09 Shiseido Co Ltd 皮膚外用剤
US20020028799A1 (en) 2000-07-06 2002-03-07 Naylor Alasdair Mark Treatment of male sexual dysfunction
HUP0002628A2 (en) 2000-07-14 2002-06-29 Keri Pharma Kft Pharmaceutical combinations for treating diabetes
US6538033B2 (en) 2000-08-29 2003-03-25 Huntington Medical Research Institutes Nitric oxide donor compounds
US6468557B1 (en) 2001-01-05 2002-10-22 Alphamed Pharmaceutical Corp. Method for treating infectious viral diseases
EP1359885A4 (en) 2001-01-25 2005-03-16 Gen Hospital Corp NOS-HEMMER FOR THE TREATMENT OF WRINKLES
WO2002087700A1 (en) 2001-04-26 2002-11-07 The Procter & Gamble Company Method, kit and device for the treatment of cosmetic skin conditions
DE10128910A1 (de) 2001-06-15 2002-12-19 Beiersdorf Ag Verwendung von Wirkstoffkombinationen aus Arginin und Ascorbinsäure zur Hautstraffung
WO2003049593A2 (en) 2001-12-06 2003-06-19 Duke University Prevention of flap necrosis in plastic surgery
US20030157185A1 (en) 2002-02-08 2003-08-21 Lou Paradise Topical treatment of neuropathy
JP4229842B2 (ja) 2002-02-22 2009-02-25 ルバンス セラピュティックス インク． Ｌ−アルギニンオリゴマーを含む化粧品処方
WO2003078437A1 (en) 2002-03-20 2003-09-25 The University Of Queensland Methods and compositions comprising nitric oxide donors and opioid analgesics
WO2003080104A2 (en) 2002-03-22 2003-10-02 Applied Research Systems Ars Holding N.V. Use of il-18 inhibitors for the treatment and/or prevention of peripheral vascular diseases
JP2003286129A (ja) 2002-03-27 2003-10-07 Hakugen:Kk 痩身シート材
US20030203915A1 (en) 2002-04-05 2003-10-30 Xinqin Fang Nitric oxide donors, compositions and methods of use related applications
RU2229286C2 (ru) 2002-05-27 2004-05-27 Пятигорская государственная фармацевтическая академия Мазь ибупрофена, приготовленная на полиэтиленоксидной основе, обладающая противовоспалительным действием
JP4419368B2 (ja) 2002-07-25 2010-02-24 小野薬品工業株式会社 プロスタグランジン誘導体およびその誘導体を有効成分として含有する薬剤
US20020168424A1 (en) 2002-07-31 2002-11-14 Dr. Mohsen Shahinpoor Nitric oxide (NO) donor+cGMP-PDE5 inhibitor as a topical drug for glaucoma
DE60236025D1 (de) 2002-08-22 2010-05-27 Vasopharm Biotech Gmbh Pharmazeutische zusammensetzung enthaltend l-arginin
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US20050271596A1 (en) * 2002-10-25 2005-12-08 Foamix Ltd. Vasoactive kit and composition and uses thereof
US7241456B2 (en) 2002-10-25 2007-07-10 Australian Importers Ltd. Formulations for topical delivery of bioactive substances and methods for their use
BR0318343A (pt) 2003-05-16 2006-07-11 Lotus Pharmaceutical Co Ltd composição tópica para administração transdérmica
AU2003903037A0 (en) 2003-06-17 2003-07-03 Institute Of Nutraceutical Research Connective tissue derived polypeptides
US20070065463A1 (en) 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
US20050069590A1 (en) 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
JP2005200370A (ja) 2004-01-16 2005-07-28 Nikko Chemical Co Ltd 一酸化窒素産生促進剤およびその利用
CA2556967A1 (en) 2004-02-23 2005-09-09 Strategic Science & Technologies, Llc Topical delivery of a nitric oxide donor to improve body and skin appearance
US20050196418A1 (en) 2004-03-04 2005-09-08 Yu Ruey J. Bioavailability and improved delivery of alkaline pharmaceutical drugs
US9205062B2 (en) 2004-03-09 2015-12-08 Mylan Pharmaceuticals, Inc. Transdermal systems containing multilayer adhesive matrices to modify drug delivery
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
AU2005235309B2 (en) 2004-04-19 2012-07-26 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US20110028548A1 (en) 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
ITMI20041492A1 (it) * 2004-07-23 2004-10-23 Italiano Biochimico Far Maceut Nuovo dispositivo per il rilascio di principi attivi
US20070087977A1 (en) 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
EP1858503B1 (en) 2005-03-03 2013-09-04 Green, Monique Renata Topical gels compositions
US7442690B2 (en) 2005-03-14 2008-10-28 P & L Enterprise Llc Topical treatment for psoriasis
MX2008003422A (es) 2005-09-16 2008-03-27 Galderma Res & Dev Composiciones que comprenden al menos un derivado de acido naftoico y al menos un compuesto de tipo polimero de poliuretano o derivados del mismo, procesos de preparacion y composiciones que comprenden al menos un derivado de acido naftoico y al meno
EP1770086A1 (de) 2005-09-29 2007-04-04 Boehringer Ingelheim Pharma GmbH & Co. KG Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
CN101340916A (zh) 2005-12-22 2009-01-07 兴和株式会社 类固醇的经时稳定性得到改善的外用制剂
FR2904549B1 (fr) 2006-08-03 2012-12-14 Sederma Sa Composition comprenant de la sarsasapogenine
US20100291236A1 (en) 2006-08-11 2010-11-18 The University Of Warwick Osmium compounds
GB2458228B (en) 2006-10-12 2011-02-23 Rohto Pharma External preparation for skin
US20100015184A1 (en) 2006-12-13 2010-01-21 Tuel Stephen M Methods of Making Pharmaceutical Components for Customized Drug Products
US8454945B2 (en) * 2007-03-22 2013-06-04 Berg Pharma Llc Topical formulations having enhanced bioavailability
US20080255103A1 (en) 2007-04-12 2008-10-16 Ballay Pharmaceuticals, Inc. Antihistamine and anti-nausea pharmaceutical compositions for topical application
JP2009196934A (ja) 2008-02-21 2009-09-03 Daiichi Sankyo Co Ltd ニューキノロン系抗菌薬及び乳剤性基剤を含む医薬組成物
US8686040B2 (en) 2008-03-31 2014-04-01 Rdd Pharma Ltd. Method for treating anal pruritis and other perianal disorders
US20100099766A1 (en) 2008-10-16 2010-04-22 Novartis Ag Topical NSAID compositions having sensate component
US8969081B2 (en) 2008-12-10 2015-03-03 The Trustees Of Columbia University In The City Of New York Caudal motor neuron derived from embryonic stem cells under conditions essentially free of any retinoid
ATE500817T1 (de) 2008-12-23 2011-03-15 Intendis Gmbh Schäumbare zusammensetzung, die im wesentlichen frei von pharmazeutisch aktiven inhaltsstoffen ist, zur behandlung der menschlichen haut
KR20110136825A (ko) 2009-03-09 2011-12-21 바이오아트라, 엘엘씨 미락 단백질
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
MX2011012043A (es) 2009-05-13 2012-03-29 Protein Delivery Solutions Llc Sistema farmaceutico para suministro transmembrana.
AU2009348470B2 (en) * 2009-06-24 2015-04-02 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
WO2010151241A1 (en) 2009-06-24 2010-12-29 Strategic Science & Technologies, Llc Topical composition containing naproxen
WO2011132826A1 (en) 2010-04-19 2011-10-27 Snu R&Db Foundation Transdermal drug delivery system and pharmaceutical composition for preventing or treating bone diseases
US20120027876A1 (en) * 2010-07-27 2012-02-02 Sara Beth Ford Composition and Method for the Topical Treatment of Dermatitis
US9289495B2 (en) 2010-12-29 2016-03-22 Strategic Science & Technologies, Llc Systems and methods for treatment of allergies and other indications
US20140010866A1 (en) 2010-12-29 2014-01-09 Strategic Science & Technologies, Llc Methods and systems for treatment of migraines and other indications
CN103429247A (zh) 2010-12-29 2013-12-04 战略科学与技术有限责任公司 勃起功能障碍和其它适应症的治疗
JP2014501286A (ja) 2010-12-29 2014-01-20 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー 真菌感染症および他の適応症に対する処置の経皮的送達
CN103442722A (zh) 2010-12-29 2013-12-11 战略科学与技术有限责任公司 Cox-2抑制剂和相关的化合物、及其递送系统和方法
EP2676142A4 (en) 2011-02-18 2015-06-03 Prec Biolog Inc METHODS AND COMPOSITIONS RELATED TO BLOOD CREATION TESTS
US8833815B2 (en) 2012-10-23 2014-09-16 Ford Global Technologies, Llc Bumper integrated forward radar mounting system
EP2968130A1 (en) 2013-03-15 2016-01-20 Strategic Science & Technologies, LLC Transdermal delivery of sildenafil and other phosphodiesterase type 5 inhibitors
CN105377233A (zh) 2013-03-15 2016-03-02 战略科学与技术有限责任公司 氟替卡松的透皮制剂
US9819429B2 (en) 2014-10-21 2017-11-14 Qualcomm Innovation Center, Inc. Efficient load sharing and accelerating of audio post-processing
JP2016087702A (ja) 2014-10-29 2016-05-23 日立工機株式会社 電動工具

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