JP2019513347A - 複数のキメラ抗原受容体（ｃａｒ）分子を発現する細胞およびその使用 - Google Patents

複数のキメラ抗原受容体（ｃａｒ）分子を発現する細胞およびその使用 Download PDF

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JP2019513347A
JP2019513347A JP2018546503A JP2018546503A JP2019513347A JP 2019513347 A JP2019513347 A JP 2019513347A JP 2018546503 A JP2018546503 A JP 2018546503A JP 2018546503 A JP2018546503 A JP 2018546503A JP 2019513347 A JP2019513347 A JP 2019513347A
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cell
amino acid
car
acid sequence
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グレン・ドラノフ
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ノバルティス アーゲー
ノバルティス アーゲー
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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JP2018546503A 2016-03-04 2017-03-03 複数のキメラ抗原受容体（ｃａｒ）分子を発現する細胞およびその使用 Pending JP2019513347A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662303466P 2016-03-04 2016-03-04
US62/303,466 2016-03-04
PCT/IB2017/051267 WO2017149515A1 (en) 2016-03-04 2017-03-03 Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore

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JP2019513347A true JP2019513347A (ja) 2019-05-30
JP2019513347A5 JP2019513347A5 (https=) 2020-04-16

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US (2) US20200281973A1 (https=)
EP (1) EP3423482A1 (https=)
JP (1) JP2019513347A (https=)
KR (1) KR20180118175A (https=)
CN (1) CN109153714A (https=)
AU (1) AU2017225733A1 (https=)
BR (1) BR112018067679A2 (https=)
CA (1) CA3016287A1 (https=)
IL (1) IL261525A (https=)
MX (1) MX2018010733A (https=)
RU (1) RU2018134771A (https=)
SG (1) SG11201807489PA (https=)
WO (1) WO2017149515A1 (https=)

Cited By (4)

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JP2018065805A (ja) * 2016-10-20 2018-04-26 ミルテニー バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｉｌｔｅｎｙｉ Ｂｉｏｔｅｃ ＧｍｂＨ 腫瘍細胞に特異的なキメラ抗原レセプター
JP2022544580A (ja) * 2019-08-16 2022-10-19 エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド 骨髄性悪性腫瘍を処置するためのキメラ抗原受容体
JP2023518538A (ja) * 2020-03-20 2023-05-02 インセルム（インスティチュート ナショナル デ ラ サンテ エ デ ラ リシェルシェ メディカル） ヒトｃｄ４５ｒｃに特異的なキメラ抗原受容体およびその使用
WO2024128081A1 (ja) * 2022-12-16 2024-06-20 東亞合成株式会社 合成ペプチド及び構築物

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EP2970426B1 (en) 2013-03-15 2019-08-28 Michael C. Milone Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
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JP6905163B2 (ja) 2015-09-03 2021-07-21 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア サイトカイン放出症候群を予測するバイオマーカー
US11052111B2 (en) 2015-12-08 2021-07-06 Chimera Bioengineering, Inc. Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses
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EP3458077A4 (en) 2016-05-17 2020-04-01 Chimera Bioengineering Inc. METHODS OF MANUFACTURING NEW AREAS OF ANTIGEN BINDING
JP7114490B2 (ja) * 2016-06-24 2022-08-08 アイセル・ジーン・セラピューティクス・エルエルシー キメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法
NZ750256A (en) 2016-08-03 2026-02-27 Dipersio John F Gene editing of car-t cells for the treatment of t cell malignancies with chimeric antigen receptors
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SG11201903830TA (en) 2016-11-22 2019-05-30 Nat Univ Singapore Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
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