JP2019510478A5 - - Google Patents
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- JP2019510478A5 JP2019510478A5 JP2018541289A JP2018541289A JP2019510478A5 JP 2019510478 A5 JP2019510478 A5 JP 2019510478A5 JP 2018541289 A JP2018541289 A JP 2018541289A JP 2018541289 A JP2018541289 A JP 2018541289A JP 2019510478 A5 JP2019510478 A5 JP 2019510478A5
- Authority
- JP
- Japan
- Prior art keywords
- chimeric protein
- protein according
- antibody
- mutation
- recognition domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108020001507 fusion proteins Proteins 0.000 claims 15
- 102000037865 fusion proteins Human genes 0.000 claims 15
- 102100040678 Programmed cell death protein 1 Human genes 0.000 claims 6
- 101710089372 Programmed cell death protein 1 Proteins 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 6
- 101000959794 Homo sapiens Interferon alpha-2 Proteins 0.000 claims 3
- 230000011664 signaling Effects 0.000 claims 3
- 230000008685 targeting Effects 0.000 claims 3
- 108010003723 Single-Domain Antibodies Proteins 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 108091023037 Aptamer Proteins 0.000 claims 1
- 241000251730 Chondrichthyes Species 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022110687A JP2022153437A (ja) | 2016-02-05 | 2022-07-08 | 標的療法剤およびその使用 |
| JP2024133824A JP2024164840A (ja) | 2016-02-05 | 2024-08-09 | 標的療法剤およびその使用 |
Applications Claiming Priority (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662291776P | 2016-02-05 | 2016-02-05 | |
| US201662291772P | 2016-02-05 | 2016-02-05 | |
| US201662291779P | 2016-02-05 | 2016-02-05 | |
| US201662291774P | 2016-02-05 | 2016-02-05 | |
| US201662291769P | 2016-02-05 | 2016-02-05 | |
| US62/291,774 | 2016-02-05 | ||
| US62/291,776 | 2016-02-05 | ||
| US62/291,779 | 2016-02-05 | ||
| US62/291,769 | 2016-02-05 | ||
| US62/291,772 | 2016-02-05 | ||
| US201662335965P | 2016-05-13 | 2016-05-13 | |
| US201662335968P | 2016-05-13 | 2016-05-13 | |
| US201662335880P | 2016-05-13 | 2016-05-13 | |
| US201662335979P | 2016-05-13 | 2016-05-13 | |
| US201662336030P | 2016-05-13 | 2016-05-13 | |
| US62/335,965 | 2016-05-13 | ||
| US62/335,979 | 2016-05-13 | ||
| US62/335,880 | 2016-05-13 | ||
| US62/336,030 | 2016-05-13 | ||
| US62/335,968 | 2016-05-13 | ||
| US201662353607P | 2016-06-23 | 2016-06-23 | |
| US62/353,607 | 2016-06-23 | ||
| US201662411805P | 2016-10-24 | 2016-10-24 | |
| US62/411,805 | 2016-10-24 | ||
| PCT/EP2017/052545 WO2017134302A2 (en) | 2016-02-05 | 2017-02-06 | Targeted therapeutic agents and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022110687A Division JP2022153437A (ja) | 2016-02-05 | 2022-07-08 | 標的療法剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019510478A JP2019510478A (ja) | 2019-04-18 |
| JP2019510478A5 true JP2019510478A5 (enExample) | 2020-03-19 |
| JP7166923B2 JP7166923B2 (ja) | 2022-11-08 |
Family
ID=57995193
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541357A Active JP7030704B2 (ja) | 2016-02-05 | 2017-02-06 | 二重特異性シグナル伝達物質およびその使用 |
| JP2018541289A Active JP7166923B2 (ja) | 2016-02-05 | 2017-02-06 | 標的療法剤およびその使用 |
| JP2018541133A Active JP7236273B2 (ja) | 2016-02-05 | 2017-02-06 | Ｃｌｅｃ９ａ結合物質 |
| JP2018540141A Active JP6991979B2 (ja) | 2016-02-05 | 2017-02-06 | Ｃｄ８結合物質 |
| JP2022025686A Active JP7386277B2 (ja) | 2016-02-05 | 2022-02-22 | 二重特異性シグナル伝達物質およびその使用 |
| JP2022110687A Pending JP2022153437A (ja) | 2016-02-05 | 2022-07-08 | 標的療法剤およびその使用 |
| JP2024133824A Pending JP2024164840A (ja) | 2016-02-05 | 2024-08-09 | 標的療法剤およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541357A Active JP7030704B2 (ja) | 2016-02-05 | 2017-02-06 | 二重特異性シグナル伝達物質およびその使用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541133A Active JP7236273B2 (ja) | 2016-02-05 | 2017-02-06 | Ｃｌｅｃ９ａ結合物質 |
| JP2018540141A Active JP6991979B2 (ja) | 2016-02-05 | 2017-02-06 | Ｃｄ８結合物質 |
| JP2022025686A Active JP7386277B2 (ja) | 2016-02-05 | 2022-02-22 | 二重特異性シグナル伝達物質およびその使用 |
| JP2022110687A Pending JP2022153437A (ja) | 2016-02-05 | 2022-07-08 | 標的療法剤およびその使用 |
| JP2024133824A Pending JP2024164840A (ja) | 2016-02-05 | 2024-08-09 | 標的療法剤およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US10988538B2 (enExample) |
| EP (8) | EP3998281A1 (enExample) |
| JP (7) | JP7030704B2 (enExample) |
| CN (9) | CN117024599A (enExample) |
| CA (4) | CA3013551A1 (enExample) |
| DK (3) | DK3411398T3 (enExample) |
| ES (3) | ES2981730T3 (enExample) |
| WO (4) | WO2017134301A1 (enExample) |
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