JP2017048240A5 - - Google Patents
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- JP2017048240A5 JP2017048240A5 JP2016226619A JP2016226619A JP2017048240A5 JP 2017048240 A5 JP2017048240 A5 JP 2017048240A5 JP 2016226619 A JP2016226619 A JP 2016226619A JP 2016226619 A JP2016226619 A JP 2016226619A JP 2017048240 A5 JP2017048240 A5 JP 2017048240A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- antibody
- immunoconjugate
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000003275 alpha amino acid group Chemical group 0.000 claims 18
- 239000000427 antigen Substances 0.000 claims 13
- 102000036639 antigens Human genes 0.000 claims 13
- 108091007433 antigens Proteins 0.000 claims 13
- 239000012634 fragment Substances 0.000 claims 13
- 229940127121 immunoconjugate Drugs 0.000 claims 13
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 3
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 3
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 108060003951 Immunoglobulin Proteins 0.000 claims 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 108010044540 auristatin Proteins 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 102000018358 immunoglobulin Human genes 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 210000003734 kidney Anatomy 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 230000017066 negative regulation of growth Effects 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45665203P | 2003-03-19 | 2003-03-19 | |
| US60/456,652 | 2003-03-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011203584A Division JP6103801B2 (ja) | 2003-03-19 | 2011-09-16 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018075311A Division JP2018150305A (ja) | 2003-03-19 | 2018-04-10 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017048240A JP2017048240A (ja) | 2017-03-09 |
| JP2017048240A5 true JP2017048240A5 (enExample) | 2017-04-13 |
Family
ID=33098138
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507388A Pending JP2007525434A (ja) | 2003-03-19 | 2004-03-19 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2011203584A Expired - Fee Related JP6103801B2 (ja) | 2003-03-19 | 2011-09-16 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2014082974A Pending JP2014144971A (ja) | 2003-03-19 | 2014-04-14 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2016226619A Ceased JP2017048240A (ja) | 2003-03-19 | 2016-11-22 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2018075311A Pending JP2018150305A (ja) | 2003-03-19 | 2018-04-10 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507388A Pending JP2007525434A (ja) | 2003-03-19 | 2004-03-19 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2011203584A Expired - Fee Related JP6103801B2 (ja) | 2003-03-19 | 2011-09-16 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
| JP2014082974A Pending JP2014144971A (ja) | 2003-03-19 | 2014-04-14 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018075311A Pending JP2018150305A (ja) | 2003-03-19 | 2018-04-10 | T細胞、免疫グロブリンドメインおよびムチンドメイン1(tim−1)抗原に対する抗体およびその使用。 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8067544B2 (enExample) |
| EP (2) | EP3000886A1 (enExample) |
| JP (5) | JP2007525434A (enExample) |
| AU (2) | AU2004224390A1 (enExample) |
| CA (1) | CA2519528C (enExample) |
| DK (1) | DK1613750T3 (enExample) |
| ES (1) | ES2557769T3 (enExample) |
| WO (1) | WO2004084823A2 (enExample) |
Families Citing this family (40)
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| NZ605429A (en) * | 2002-09-06 | 2014-08-29 | Amgen Inc | Therapeutic human anti-il-1r1 monoclonal antibody |
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| DK1613750T3 (en) | 2003-03-19 | 2016-01-18 | Amgen Fremont Inc | ANTIBODIES TO T CELL AND MUCINDO immunoglobulin-binding domain 1 (TIM-1) antigen and uses thereof |
| US7736644B2 (en) * | 2003-06-27 | 2010-06-15 | Amgen Fremont Inc. | Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof |
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| EP2548583A3 (en) * | 2005-11-10 | 2013-02-27 | Curagen Corporation | Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen |
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| CL2008002083A1 (es) | 2007-07-16 | 2008-11-21 | Genentech Inc | Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico |
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| WO2009064290A1 (en) * | 2007-11-13 | 2009-05-22 | Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Structure of tim family members |
| RS54883B1 (sr) | 2008-01-31 | 2016-10-31 | Genentech Inc | Anti-cd79b antitela i imunokonjugati i metode upotrebe |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| US20130156784A1 (en) * | 2008-08-20 | 2013-06-20 | Michael Jeffers | Compositions Using Antibodies Directed To GPNMB And Uses Thereof |
| WO2010135547A1 (en) * | 2009-05-20 | 2010-11-25 | Celldex Therapeutics, Inc. | Antibodies directed to gpnmb and uses thereof |
| AU2012316859A1 (en) * | 2011-09-29 | 2014-04-17 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| EP2802356A1 (en) | 2012-01-13 | 2014-11-19 | Apo-T B.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| WO2014018464A1 (en) * | 2012-07-23 | 2014-01-30 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of sepsis |
| RS60349B8 (sr) | 2014-09-23 | 2022-10-31 | Hoffmann La Roche | Postupak upotrebe anti-cd79b imunokonjugata |
| JP6709215B2 (ja) | 2014-10-27 | 2020-06-10 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 抗tim−3抗体 |
| GB201419094D0 (en) | 2014-10-27 | 2014-12-10 | Agency Science Tech & Res | Anti-TIM-3-antibodies |
| GB201419084D0 (en) | 2014-10-27 | 2014-12-10 | Agency Science Tech & Res | Anti-PD-1 antibodies |
| US20180044429A1 (en) | 2015-03-09 | 2018-02-15 | Celldex Therapeutics, Inc. | Cd27 agonists |
| US20200140851A1 (en) * | 2016-08-23 | 2020-05-07 | The Scripps Research Institute | Methods and Compositions Related to In Vivo Selection of Functional Molecules |
| JP7303749B2 (ja) * | 2017-01-13 | 2023-07-05 | セルダラ メディカル、エルエルシー | Tim-1を標的とするキメラ抗原受容体 |
| RU2674894C2 (ru) * | 2017-01-30 | 2018-12-13 | Общество с ограниченной ответственностью "ПЛАНТА" | Новые люциферазы и способы их использования |
| CN109265549A (zh) * | 2018-09-25 | 2019-01-25 | 中国人民解放军军事科学院军事医学研究院 | 一种具有中和活性的抗人Tim-1抗体 |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
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| CA2479732A1 (en) * | 2002-03-19 | 2003-10-02 | Curagen Corporation | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| EP2289559B1 (en) | 2003-02-20 | 2014-02-12 | Seattle Genetics, Inc. | Anit-CD70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders |
| DK1613750T3 (en) * | 2003-03-19 | 2016-01-18 | Amgen Fremont Inc | ANTIBODIES TO T CELL AND MUCINDO immunoglobulin-binding domain 1 (TIM-1) antigen and uses thereof |
| US20050119210A1 (en) * | 2003-05-20 | 2005-06-02 | Xiaobing Be | Compositions and methods for diagnosing and treating cancers |
| JP6071725B2 (ja) | 2013-04-23 | 2017-02-01 | カルソニックカンセイ株式会社 | 電気自動車の駆動力制御装置 |
| US11284893B2 (en) | 2019-04-02 | 2022-03-29 | Covidien Lp | Stapling device with articulating tool assembly |
-
2004
- 2004-03-19 DK DK04757910.7T patent/DK1613750T3/en active
- 2004-03-19 AU AU2004224390A patent/AU2004224390A1/en not_active Abandoned
- 2004-03-19 US US10/805,177 patent/US8067544B2/en not_active Expired - Fee Related
- 2004-03-19 JP JP2006507388A patent/JP2007525434A/ja active Pending
- 2004-03-19 ES ES04757910.7T patent/ES2557769T3/es not_active Expired - Lifetime
- 2004-03-19 EP EP15189243.7A patent/EP3000886A1/en not_active Withdrawn
- 2004-03-19 CA CA2519528A patent/CA2519528C/en not_active Expired - Fee Related
- 2004-03-19 EP EP04757910.7A patent/EP1613750B1/en not_active Expired - Lifetime
- 2004-03-19 WO PCT/US2004/008502 patent/WO2004084823A2/en not_active Ceased
-
2010
- 2010-10-07 AU AU2010227016A patent/AU2010227016A1/en not_active Abandoned
-
2011
- 2011-09-16 JP JP2011203584A patent/JP6103801B2/ja not_active Expired - Fee Related
- 2011-11-29 US US13/305,898 patent/US9580503B2/en not_active Expired - Fee Related
-
2014
- 2014-04-14 JP JP2014082974A patent/JP2014144971A/ja active Pending
-
2016
- 2016-11-22 JP JP2016226619A patent/JP2017048240A/ja not_active Ceased
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2017
- 2017-02-24 US US15/442,083 patent/US20170218067A1/en not_active Abandoned
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2018
- 2018-04-10 JP JP2018075311A patent/JP2018150305A/ja active Pending
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