JP2017500057A5 - - Google Patents

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Publication number
JP2017500057A5
JP2017500057A5 JP2016553248A JP2016553248A JP2017500057A5 JP 2017500057 A5 JP2017500057 A5 JP 2017500057A5 JP 2016553248 A JP2016553248 A JP 2016553248A JP 2016553248 A JP2016553248 A JP 2016553248A JP 2017500057 A5 JP2017500057 A5 JP 2017500057A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
set forth
sequence set
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JP2016553248A
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English (en)
Japanese (ja)
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JP6553069B2 (ja
JP2017500057A (ja
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Priority claimed from PCT/US2014/064621 external-priority patent/WO2015070061A1/en
Publication of JP2017500057A publication Critical patent/JP2017500057A/ja
Publication of JP2017500057A5 publication Critical patent/JP2017500057A5/ja
Application granted granted Critical
Publication of JP6553069B2 publication Critical patent/JP6553069B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016553248A 2013-11-07 2014-11-07 抗wt1/hla二重特異性抗体 Expired - Fee Related JP6553069B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361901310P 2013-11-07 2013-11-07
US61/901,310 2013-11-07
US201462037875P 2014-08-15 2014-08-15
US62/037,875 2014-08-15
PCT/US2014/064621 WO2015070061A1 (en) 2013-11-07 2014-11-07 Anti-wt1/hla bi-specific antibody

Publications (3)

Publication Number Publication Date
JP2017500057A JP2017500057A (ja) 2017-01-05
JP2017500057A5 true JP2017500057A5 (enExample) 2018-05-10
JP6553069B2 JP6553069B2 (ja) 2019-07-31

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ID=51987482

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016553248A Expired - Fee Related JP6553069B2 (ja) 2013-11-07 2014-11-07 抗wt1/hla二重特異性抗体

Country Status (5)

Country Link
EP (1) EP3066130B1 (enExample)
JP (1) JP6553069B2 (enExample)
CN (1) CN106414500B (enExample)
ES (1) ES2742224T3 (enExample)
WO (1) WO2015070061A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
HK1258444A1 (zh) 2015-10-09 2019-11-15 Immatics Biotechnologies Gmbh 抗wt1/hla特异性抗体
WO2017070608A1 (en) 2015-10-23 2017-04-27 Eureka Therapeutics, Inc. Antibody/t-cell receptor chimeric constructs and uses thereof
WO2017124001A2 (en) * 2016-01-14 2017-07-20 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for foxp3-derived peptides
EP4491234A3 (en) 2017-02-08 2025-04-09 Dragonfly Therapeutics, Inc. Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
BR112019017197A2 (pt) 2017-02-20 2020-04-14 Dragonfly Therapeutics, Inc. proteínas que se ligam a her2, nkg2d e cd16
CN110741016A (zh) 2017-04-26 2020-01-31 优瑞科生物技术公司 嵌合抗体/t-细胞受体构筑体及其用途
US12178830B2 (en) 2017-06-30 2024-12-31 Memorial Sloan Kettering Cancer Center Compositions and methods for adoptive cell therapy for cancer
JP7072792B2 (ja) * 2017-12-11 2022-05-23 国立大学法人神戸大学 二重特異性抗体
EP3728317A2 (en) 2017-12-21 2020-10-28 F. Hoffmann-La Roche AG Antibodies binding to hla-a2/wt1
PE20220278A1 (es) 2018-02-08 2022-02-25 Dragonfly Therapeutics Inc Dominios variables de anticuerpos que se dirigen al receptor nkg2d
AU2019218125B2 (en) 2018-02-08 2025-03-13 Dragonfly Therapeutics, Inc. Combination therapy of cancer involving multi-specific binding proteins that activate natural killer cells
WO2019161133A1 (en) 2018-02-15 2019-08-22 Memorial Sloan Kettering Cancer Center Foxp3 targeting agent compositions and methods of use for adoptive cell therapy
TW201942134A (zh) 2018-02-20 2019-11-01 美商蜻蜓醫療公司 結合cd33、nkg2d及cd16之多特異性結合蛋白及使用方法
CA3100775A1 (en) * 2018-05-18 2019-11-21 Children's National Medical Center Improved targeted t-cell therapy
KR20250112921A (ko) 2018-08-08 2025-07-24 드래곤플라이 쎄라퓨틱스, 인크. Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
EA202190468A1 (ru) 2018-08-08 2021-07-06 Драгонфлай Терапьютикс, Инк. Мультиспецифические связывающие белки, которые связывают bcma, nkg2d и cd16, и способы их применения
US20240383999A1 (en) * 2020-04-02 2024-11-21 The Board Of Regents Of The University Of Texas System Cd5l-binding antibodies and uses for the same
EP4146271A4 (en) 2020-05-06 2024-09-04 Dragonfly Therapeutics, Inc. PROTEINS THAT BIND NKG2D, CD16 AND CLEC12A
EP4216998A1 (en) * 2020-09-24 2023-08-02 F. Hoffmann-La Roche AG Prevention or mitigation of t-cell bispecific antibody-related adverse effects
CN116635064A (zh) 2020-12-18 2023-08-22 世纪治疗股份有限公司 具有适应性受体特异性的嵌合抗原受体系统
US12377144B2 (en) 2021-03-03 2025-08-05 Dragonfly Therapeutics, Inc. Methods of treating cancer using multi-specific binding proteins that bind NKG2D, CD16 and a tumor-associated antigen
KR20240158351A (ko) * 2022-03-22 2024-11-04 모르포시스 아게 Cd3에 특이적인 탈면역화 항체

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885573A (en) * 1993-06-01 1999-03-23 Arch Development Corporation Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
JP4948174B2 (ja) * 2003-10-16 2012-06-06 マイクロメット アクツィエン ゲゼルシャフト 多重特異的脱免疫cd3−結合物質
RU2008129827A (ru) * 2005-12-21 2010-01-27 МЕДИММЬЮН, ЭлЭлСи (US) МОЛЕКУЛЫ EphA2-BiTE И ИХ ПРИМЕНЕНИЕ
PH12013502043A1 (en) * 2011-04-01 2013-12-16 Memorial Sloan Kettering Cancer Center T cell receptor-like antibodies specific for a wt1 peptide presented by hla-a2

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