JP2020508334A5 - - Google Patents
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- JP2020508334A5 JP2020508334A5 JP2019546216A JP2019546216A JP2020508334A5 JP 2020508334 A5 JP2020508334 A5 JP 2020508334A5 JP 2019546216 A JP2019546216 A JP 2019546216A JP 2019546216 A JP2019546216 A JP 2019546216A JP 2020508334 A5 JP2020508334 A5 JP 2020508334A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463353P | 2017-02-24 | 2017-02-24 | |
| US62/463,353 | 2017-02-24 | ||
| US201762597594P | 2017-12-12 | 2017-12-12 | |
| US62/597,594 | 2017-12-12 | ||
| PCT/US2018/019188 WO2018156740A1 (en) | 2017-02-24 | 2018-02-22 | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020508334A JP2020508334A (ja) | 2020-03-19 |
| JP2020508334A5 true JP2020508334A5 (enExample) | 2021-04-01 |
| JP7132232B2 JP7132232B2 (ja) | 2022-09-06 |
Family
ID=63252984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019546216A Active JP7132232B2 (ja) | 2017-02-24 | 2018-02-22 | Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11459394B2 (enExample) |
| EP (2) | EP3585431A4 (enExample) |
| JP (1) | JP7132232B2 (enExample) |
| KR (1) | KR102585848B1 (enExample) |
| CN (1) | CN110325209A (enExample) |
| AU (1) | AU2018224094B2 (enExample) |
| BR (1) | BR112019017628A2 (enExample) |
| CA (1) | CA3053803A1 (enExample) |
| IL (1) | IL268836B2 (enExample) |
| MA (1) | MA47612A (enExample) |
| MX (1) | MX2019009967A (enExample) |
| SG (1) | SG11201907753TA (enExample) |
| TW (1) | TWI788327B (enExample) |
| WO (1) | WO2018156740A1 (enExample) |
| ZA (1) | ZA201905347B (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201913680PA (en) * | 2014-05-29 | 2020-03-30 | Macrogenics Inc | Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof |
| AP2017009823A0 (en) * | 2014-09-26 | 2017-03-31 | Macrogenics Inc | Bi-specific monovalent diabodies that are capable of binding cd19 and cd3, and uses thereof |
| KR102754019B1 (ko) | 2014-10-29 | 2025-01-14 | 바이시클러드 리미티드 | Mt1-mmp에 특이적인 바이사이클릭 펩타이드 리간드 |
| CA3020864A1 (en) * | 2016-04-15 | 2017-10-19 | Macrogenics, Inc. | Novel b7-h3-binding molecules, antibody drug conjugates thereof and methods of use thereof |
| WO2017182672A1 (en) | 2016-04-22 | 2017-10-26 | Alligator Bioscience Ab | Novel bispecific polypeptides against cd137 |
| JP7132232B2 (ja) | 2017-02-24 | 2022-09-06 | マクロジェニクス，インコーポレーテッド | Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 |
| JP7297672B2 (ja) | 2017-04-13 | 2023-06-26 | アジェナス インコーポレイテッド | 抗ｃｄ１３７抗体およびその使用方法 |
| CN111032678A (zh) | 2017-06-26 | 2020-04-17 | 拜西克尔德有限公司 | 具有可检测部分的双环肽配体和其用途 |
| IL272103B2 (en) | 2017-07-20 | 2024-10-01 | Aptevo Res & Development Llc | Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods of treating cancer |
| ES2926195T3 (es) | 2017-08-04 | 2022-10-24 | Bicycletx Ltd | Ligandos peptídicos bicíclicos específicos de CD137 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| AU2019224659A1 (en) | 2018-02-23 | 2020-10-15 | Bicycletx Limited | Multimeric bicyclic peptide ligands |
| US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| AU2019312200B2 (en) | 2018-07-23 | 2024-11-14 | Heidelberg Pharma Research Gmbh | Use of anti-CD137 antibody drug conjugate (ADC) in allogeneic cell therapy |
| SG11202102272UA (en) * | 2018-09-05 | 2021-04-29 | Univ Arizona State | Oncolytic virus platform to treat hematological cancer |
| TWI839395B (zh) * | 2018-10-09 | 2024-04-21 | 瑞士商Ｎｕｍａｂ治療公司 | 靶向cd137的抗體及其使用方法 |
| CN112996809A (zh) * | 2018-10-10 | 2021-06-18 | 酵活有限公司 | 结合4-1bb和肿瘤相关抗原的抗体构建体以及其用途 |
| JP7410143B2 (ja) * | 2018-11-01 | 2024-01-09 | 山▲東▼新▲時▼代▲薬▼▲業▼有限公司 | 二重特異性抗体及びその用途 |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| US12551567B2 (en) | 2018-12-21 | 2026-02-17 | Bicyclerd Limited | Bicyclic peptide ligands specific for PD-L1 |
| CN113474045A (zh) | 2018-12-21 | 2021-10-01 | 拜斯科技术开发有限公司 | Pd-l1特异性的双环肽配体 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| MX2021012961A (es) | 2019-04-24 | 2021-11-25 | Heidelberg Pharma Res Gmbh | Conjugados de anticuerpo y farmaco de amatoxina y usos de los mismos. |
| AU2020269506A1 (en) | 2019-05-09 | 2022-01-06 | Bicycletx Limited | Bicyclic peptide ligands specific for OX40 |
| US11725058B2 (en) * | 2019-06-26 | 2023-08-15 | Ap Biosciences, Inc. | CD137 antibodies for T-cell activation |
| US12240913B2 (en) * | 2019-07-26 | 2025-03-04 | Abl Bio Inc. | Anti-HER2/anti-4-1BB bispecific antibody and use thereof |
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- 2018-02-22 JP JP2019546216A patent/JP7132232B2/ja active Active
- 2018-02-22 EP EP18757875.2A patent/EP3585431A4/en not_active Withdrawn
- 2018-02-22 MA MA047612A patent/MA47612A/fr unknown
- 2018-02-22 EP EP24171071.4A patent/EP4389226A3/en active Pending
- 2018-02-22 CA CA3053803A patent/CA3053803A1/en active Pending
- 2018-02-22 CN CN201880013509.6A patent/CN110325209A/zh active Pending
- 2018-02-22 SG SG11201907753TA patent/SG11201907753TA/en unknown
- 2018-02-22 US US16/488,025 patent/US11459394B2/en active Active
- 2018-02-22 MX MX2019009967A patent/MX2019009967A/es unknown
- 2018-02-22 IL IL268836A patent/IL268836B2/en unknown
- 2018-02-22 KR KR1020197027622A patent/KR102585848B1/ko active Active
- 2018-02-22 WO PCT/US2018/019188 patent/WO2018156740A1/en not_active Ceased
- 2018-02-22 AU AU2018224094A patent/AU2018224094B2/en active Active
- 2018-02-22 BR BR112019017628-4A patent/BR112019017628A2/pt active Search and Examination
- 2018-02-23 TW TW107106261A patent/TWI788327B/zh not_active IP Right Cessation
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2019
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