JP7132232B2 - Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 - Google Patents

Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 Download PDF

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JP7132232B2
JP7132232B2 JP2019546216A JP2019546216A JP7132232B2 JP 7132232 B2 JP7132232 B2 JP 7132232B2 JP 2019546216 A JP2019546216 A JP 2019546216A JP 2019546216 A JP2019546216 A JP 2019546216A JP 7132232 B2 JP7132232 B2 JP 7132232B2
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seq
cdr
mab
binding
binding molecule
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JP2020508334A5 (enExample
JP2020508334A (ja
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リキン リュウ
チャーイン カオ ラム
グンド ディードリッヒ
レスリー エス． ジョンソン
ポール エー． ムーア
エツィオ ボンビニ
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マクロジェニクス，インコーポレーテッド
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07—ORGANIC CHEMISTRY
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JP2019546216A 2017-02-24 2018-02-22 Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 Expired - Fee Related JP7132232B2 (ja)

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Application Number Priority Date Filing Date Title
US201762463353P 2017-02-24 2017-02-24
US62/463,353 2017-02-24
US201762597594P 2017-12-12 2017-12-12
US62/597,594 2017-12-12
PCT/US2018/019188 WO2018156740A1 (en) 2017-02-24 2018-02-22 Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof

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JP2020508334A JP2020508334A (ja) 2020-03-19
JP2020508334A5 JP2020508334A5 (enExample) 2021-04-01
JP7132232B2 true JP7132232B2 (ja) 2022-09-06

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US (3) US11459394B2 (enExample)
EP (2) EP4389226A3 (enExample)
JP (1) JP7132232B2 (enExample)
KR (1) KR102585848B1 (enExample)
CN (1) CN110325209A (enExample)
AU (1) AU2018224094B2 (enExample)
BR (1) BR112019017628A2 (enExample)
CA (1) CA3053803A1 (enExample)
IL (1) IL268836B2 (enExample)
MA (1) MA47612A (enExample)
MX (1) MX2019009967A (enExample)
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TW (1) TWI788327B (enExample)
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