JP2018513149A5 - - Google Patents

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Publication number
JP2018513149A5
JP2018513149A5 JP2017552973A JP2017552973A JP2018513149A5 JP 2018513149 A5 JP2018513149 A5 JP 2018513149A5 JP 2017552973 A JP2017552973 A JP 2017552973A JP 2017552973 A JP2017552973 A JP 2017552973A JP 2018513149 A5 JP2018513149 A5 JP 2018513149A5
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JP
Japan
Prior art keywords
seq
variable domain
chain variable
amino acid
antibody
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2017552973A
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English (en)
Japanese (ja)
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JP2018513149A (ja
JP7068825B2 (ja
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Priority claimed from PCT/US2016/026567 external-priority patent/WO2016164669A2/en
Publication of JP2018513149A publication Critical patent/JP2018513149A/ja
Publication of JP2018513149A5 publication Critical patent/JP2018513149A5/ja
Priority to JP2021086783A priority Critical patent/JP7273101B2/ja
Application granted granted Critical
Publication of JP7068825B2 publication Critical patent/JP7068825B2/ja
Priority to JP2022101169A priority patent/JP2022118222A/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017552973A 2015-04-08 2016-04-08 Ｃｄ３８に結合する抗体治療剤 Expired - Fee Related JP7068825B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021086783A JP7273101B2 (ja) 2015-04-08 2021-05-24 Ｃｄ３８に結合する抗体治療剤
JP2022101169A JP2022118222A (ja) 2015-04-08 2022-06-23 Ｃｄ３８に結合する抗体治療剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562144901P 2015-04-08 2015-04-08
US62/144,901 2015-04-08
PCT/US2016/026567 WO2016164669A2 (en) 2015-04-08 2016-04-08 Antibody therapeutics that bind cd38

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021086783A Division JP7273101B2 (ja) 2015-04-08 2021-05-24 Ｃｄ３８に結合する抗体治療剤

Publications (3)

Publication Number Publication Date
JP2018513149A JP2018513149A (ja) 2018-05-24
JP2018513149A5 true JP2018513149A5 (enExample) 2019-05-16
JP7068825B2 JP7068825B2 (ja) 2022-05-17

Family

ID=57072959

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017552973A Expired - Fee Related JP7068825B2 (ja) 2015-04-08 2016-04-08 Ｃｄ３８に結合する抗体治療剤
JP2021086783A Active JP7273101B2 (ja) 2015-04-08 2021-05-24 Ｃｄ３８に結合する抗体治療剤
JP2022101169A Pending JP2022118222A (ja) 2015-04-08 2022-06-23 Ｃｄ３８に結合する抗体治療剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2021086783A Active JP7273101B2 (ja) 2015-04-08 2021-05-24 Ｃｄ３８に結合する抗体治療剤
JP2022101169A Pending JP2022118222A (ja) 2015-04-08 2022-06-23 Ｃｄ３８に結合する抗体治療剤

Country Status (8)

Country Link
US (4) US9951144B2 (enExample)
EP (2) EP3280443B1 (enExample)
JP (3) JP7068825B2 (enExample)
CN (2) CN113527495A (enExample)
AR (1) AR104213A1 (enExample)
ES (1) ES2927119T3 (enExample)
TW (1) TW201702264A (enExample)
WO (2) WO2016164669A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10100118B2 (en) * 2015-04-08 2018-10-16 Sorrento Therapeutics, Inc. Antibody therapeutics that bind CD123
CN113527495A (zh) 2015-04-08 2021-10-22 索伦托药业有限公司 与cd38结合的抗体治疗剂
AU2018273914A1 (en) 2017-05-24 2019-11-14 Pandion Operations, Inc. Targeted immunotolerance
PE20242042A1 (es) 2017-06-02 2024-10-10 Pfizer Anticuerpos especificos para flt3 y sus usos
AU2018280871B2 (en) 2017-06-08 2024-09-26 Black Belt Therapeutics Ltd CD38 modulating antibody
EP3635001A1 (en) 2017-06-08 2020-04-15 Black Belt Therapeutics Limited Cd38 modulating antibody
EP4509143A3 (en) 2017-06-20 2025-04-23 Sorrento Therapeutics, Inc. Cd38 antibody drug conjugate
US11542338B2 (en) 2017-08-16 2023-01-03 Black Belt Therapeutics Limited CD38 modulating antibody
WO2019034752A1 (en) 2017-08-16 2019-02-21 Tusk Therapeutics Ltd Cd38 modulating antibody
WO2019035938A1 (en) 2017-08-16 2019-02-21 Elstar Therapeutics, Inc. MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
EP3668543A1 (en) 2017-08-16 2020-06-24 Black Belt Therapeutics Limited Cd38 antibody
CN111542545A (zh) * 2017-11-03 2020-08-14 索伦托治疗有限公司 Cd38定向嵌合抗原受体构建体
US10174091B1 (en) 2017-12-06 2019-01-08 Pandion Therapeutics, Inc. IL-2 muteins
US10946068B2 (en) 2017-12-06 2021-03-16 Pandion Operations, Inc. IL-2 muteins and uses thereof
AU2019231315A1 (en) 2018-03-09 2020-09-17 Vivasor, Inc. Dimeric antigen receptors (DAR)
KR20210022684A (ko) * 2018-06-20 2021-03-03 소렌토 쎄라퓨틱스, 인코포레이티드 Cd38에 결합하는 변이 항체
WO2020052546A1 (zh) 2018-09-11 2020-03-19 江苏恒瑞医药股份有限公司 抗cd38抗体、其抗原结合片段及医药用途
CN114524877A (zh) * 2019-03-29 2022-05-24 索伦托药业有限公司 结合cd38的经工程改造的变异抗体
CA3141327A1 (en) 2019-05-20 2020-11-26 Pandion Operations, Inc. Madcam targeted immunotolerance
CN114269770B (zh) * 2019-07-03 2025-02-25 肽梦想株式会社 Cd38结合剂及其用途
TW202124437A (zh) * 2019-08-19 2021-07-01 美商潘迪恩營運公司 以ｐｄ－１促效劑進行之標靶免疫耐受性
MX2022006787A (es) 2019-12-05 2022-07-19 Sorrento Therapeutics Inc Composiciones y metodos que comprenden un anticuerpo anti-cd47 en combinacion con un anticuerpo dirigido al tumor.
EP4107189A4 (en) * 2020-02-21 2024-07-03 Pandion Operations, Inc. TISSUE-TARGETED IMMUNOTOLERANCE WITH PD-1 AGONISTS OR IL-2 MUTEINS
WO2021168079A1 (en) 2020-02-21 2021-08-26 Pandion Operations, Inc. Tissue targeted immunotolerance with a cd39 effector
WO2022015956A1 (en) 2020-07-15 2022-01-20 Sorrento Therapeutics, Inc. Improved process for dna integration using rna-guided endonucleases
BR112023003087A2 (pt) * 2020-08-19 2023-03-28 Pandion Operations Inc Anticorpos anti-pd-1 multiparatópicos e usos dos mesmos
EP4211476A4 (en) * 2020-09-10 2024-11-13 CASI Pharmaceuticals, Inc. BLOOD SCREENING PROCEDURES

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3817827A (en) 1972-03-30 1974-06-18 Scott Paper Co Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US6010902A (en) 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
JP3051145B2 (ja) 1990-08-28 2000-06-12 住友製薬株式会社 新規なポリエチレングリコール誘導体修飾ペプチド
US5582996A (en) 1990-12-04 1996-12-10 The Wistar Institute Of Anatomy & Biology Bifunctional antibodies and method of preparing same
DE4118120A1 (de) 1991-06-03 1992-12-10 Behringwerke Ag Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化ｂ−ｂ１０
ATE240394T1 (de) 1992-10-23 2003-05-15 Immunex Corp Methoden zur herstellung löslicher, oligomerer proteine
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
EP1105427A2 (en) 1998-08-17 2001-06-13 Abgenix, Inc. Generation of modified molecules with increased serum half-lives
GB9928787D0 (en) 1999-12-03 2000-02-02 Medical Res Council Direct screening method
AU2001268427B2 (en) 2000-06-16 2007-03-29 Glaxosmithkline Intellectual Property Limited Antibodies that immunospecifically bind to blys
US6938003B2 (en) 2000-06-30 2005-08-30 Mahesh Harpale Method and apparatus for a credibility reporting system to augment an online exchange
GB0025144D0 (en) 2000-10-13 2000-11-29 Medical Res Council Concatenated nucleic acid sequences
CA2450793A1 (en) * 2001-06-20 2002-12-27 Prochon Biotech Ltd. Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
US20040202995A1 (en) 2003-04-09 2004-10-14 Domantis Nucleic acids, proteins, and screening methods
CN1976950B (zh) * 2004-02-06 2012-08-29 莫佛塞斯公司 抗cd38人抗体及其用途
ES2541436T3 (es) 2004-02-06 2015-07-20 Morphosys Ag Anticuerpos humanos anti-CD38 y usos para ellos
EP3312196B1 (en) * 2005-03-23 2019-07-17 Genmab A/S Antibodies against cd38 for treatment of multiple myeloma
PL2860192T3 (pl) * 2005-10-12 2018-03-30 Morphosys Ag Wytwarzanie i profilowanie w pełni ludzkich, uzyskanych z HuCAL GOLD terapeutycznych przeciwciał swoistych wobec ludzkiego CD38
WO2010054007A1 (en) * 2008-11-07 2010-05-14 Fabrus Llc Combinatorial antibody libraries and uses thereof
WO2010141249A2 (en) 2009-06-02 2010-12-09 Merck Sharp & Dohme Corp. Generation, characterization and uses thereof of anti-notch3 antibodies
EP2580243B1 (en) 2010-06-09 2019-10-16 Genmab A/S Antibodies against human cd38
NZ607473A (en) * 2010-09-27 2014-11-28 Morphosys Ag Anti-cd38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and nhl
JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
US9120858B2 (en) * 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
JP2016534090A (ja) * 2013-07-15 2016-11-04 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー Ｃｄ３８アゴニストの医学的使用
CN113527495A (zh) 2015-04-08 2021-10-22 索伦托药业有限公司 与cd38结合的抗体治疗剂

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