ES2927119T3 - Productos terapéuticos de anticuerpos que se unen a CD38 - Google Patents
Productos terapéuticos de anticuerpos que se unen a CD38 Download PDFInfo
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- ES2927119T3 ES2927119T3 ES16777327T ES16777327T ES2927119T3 ES 2927119 T3 ES2927119 T3 ES 2927119T3 ES 16777327 T ES16777327 T ES 16777327T ES 16777327 T ES16777327 T ES 16777327T ES 2927119 T3 ES2927119 T3 ES 2927119T3
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US201562144901P | 2015-04-08 | 2015-04-08 | |
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| US10100118B2 (en) * | 2015-04-08 | 2018-10-16 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind CD123 |
| TW201702264A (zh) | 2015-04-08 | 2017-01-16 | 索倫多醫療公司 | 結合ｃｄ３８之抗體治療劑 |
| JP2020521452A (ja) | 2017-05-24 | 2020-07-27 | パンディオン・セラピューティクス・インコーポレイテッド | 標的化免疫寛容 |
| KR102693777B1 (ko) | 2017-06-02 | 2024-08-08 | 화이자 인코포레이티드 | Flt3에 특이적인 항체 및 이의 용도 |
| US11780930B2 (en) | 2017-06-08 | 2023-10-10 | Black Belt Therapeutics Limited | CD38 modulating antibody |
| WO2018224685A1 (en) | 2017-06-08 | 2018-12-13 | Tusk Therapeutics Ltd | Cd38 modulating antibody |
| EP4509143A3 (en) | 2017-06-20 | 2025-04-23 | Sorrento Therapeutics, Inc. | Cd38 antibody drug conjugate |
| US11542338B2 (en) | 2017-08-16 | 2023-01-03 | Black Belt Therapeutics Limited | CD38 modulating antibody |
| WO2019035938A1 (en) | 2017-08-16 | 2019-02-21 | Elstar Therapeutics, Inc. | MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF |
| WO2019034753A1 (en) * | 2017-08-16 | 2019-02-21 | Tusk Therapeutics Ltd | ANTIBODY CD38 |
| WO2019034752A1 (en) | 2017-08-16 | 2019-02-21 | Tusk Therapeutics Ltd | CD38 MODULATOR ANTIBODY |
| CN111542545A (zh) * | 2017-11-03 | 2020-08-14 | 索伦托治疗有限公司 | Cd38定向嵌合抗原受体构建体 |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| EP3762430A4 (en) | 2018-03-09 | 2022-03-16 | Sorrento Therapeutics, Inc. | Dimeric antigen receptors (dar) |
| EP3810655A4 (en) * | 2018-06-20 | 2022-03-16 | Sorrento Therapeutics, Inc. | CD38-BINDING ANTIBODY VARIANT |
| AU2019338999A1 (en) * | 2018-09-11 | 2021-03-18 | Jiangsu Hengrui Medicine Co., Ltd. | Anti-CD38 antibody, antigen-binding fragment thereof, and pharmaceutical use |
| EP3947465A4 (en) * | 2019-03-29 | 2023-01-04 | Sorrento Therapeutics, Inc. | MODIFIED VARIANT ANTIBODIES BINDING TO CD38 |
| EP3972992A4 (en) | 2019-05-20 | 2023-07-19 | Pandion Operations, Inc. | MADCAM TARGETED IMMUNOTLERANCE |
| EP3993874A4 (en) * | 2019-07-03 | 2023-06-28 | PeptiDream Inc. | Cd38-binding agents and uses thereof |
| KR20220050168A (ko) * | 2019-08-19 | 2022-04-22 | 팬디온 오퍼레이션스, 인코포레이티드 | Pd-1 작용제로 표적된 면역관용 |
| US20210221886A1 (en) | 2019-12-05 | 2021-07-22 | Sorrento Therapeutics, Inc. | Compositions and Methods Comprising an Anti-CD47 Antibody in Combination with a Tumor Targeting Antibody |
| US20230235004A1 (en) * | 2020-02-21 | 2023-07-27 | Pandion Operations, Inc. | Tissue targeted immunotolerance with pd-1 agonists or il-2 muteins |
| WO2021168079A1 (en) | 2020-02-21 | 2021-08-26 | Pandion Operations, Inc. | Tissue targeted immunotolerance with a cd39 effector |
| WO2022015956A1 (en) | 2020-07-15 | 2022-01-20 | Sorrento Therapeutics, Inc. | Improved process for dna integration using rna-guided endonucleases |
| KR20230048144A (ko) * | 2020-08-19 | 2023-04-10 | 팬디온 오퍼레이션스, 인코포레이티드 | 다중-파라토프 항-pd-1 항체 및 그의 용도 |
| JP2023541254A (ja) * | 2020-09-10 | 2023-09-29 | キャシ ファーマシューティカルズ インコーポレイテッド | 血液スクリーニング方法 |
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| US3817827A (en) | 1972-03-30 | 1974-06-18 | Scott Paper Co | Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
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| JP2021118754A (ja) | 2021-08-12 |
| US20200399395A1 (en) | 2020-12-24 |
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| US20160297888A1 (en) | 2016-10-13 |
| US20190048092A1 (en) | 2019-02-14 |
| HK1253584A1 (zh) | 2019-06-21 |
| CN113527495A (zh) | 2021-10-22 |
| JP2022118222A (ja) | 2022-08-12 |
| TW201702264A (zh) | 2017-01-16 |
| JP2018513149A (ja) | 2018-05-24 |
| EP4180058A1 (en) | 2023-05-17 |
| EP3280443A4 (en) | 2018-12-26 |
| US10059774B2 (en) | 2018-08-28 |
| CN107921122B (zh) | 2021-08-10 |
| JP7273101B2 (ja) | 2023-05-12 |
| WO2016164656A1 (en) | 2016-10-13 |
| WO2016164669A3 (en) | 2017-01-12 |
| EP3280443A2 (en) | 2018-02-14 |
| US9951144B2 (en) | 2018-04-24 |
| EP3280443B1 (en) | 2022-08-24 |
| US11999792B2 (en) | 2024-06-04 |
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