JP2020502147A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020502147A5 JP2020502147A5 JP2019531988A JP2019531988A JP2020502147A5 JP 2020502147 A5 JP2020502147 A5 JP 2020502147A5 JP 2019531988 A JP2019531988 A JP 2019531988A JP 2019531988 A JP2019531988 A JP 2019531988A JP 2020502147 A5 JP2020502147 A5 JP 2020502147A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nos
- antibody
- cdr
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022189027A JP2023026426A (ja) | 2016-12-15 | 2022-11-28 | 制御性ｂ１０細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434833P | 2016-12-15 | 2016-12-15 | |
| US62/434,833 | 2016-12-15 | ||
| PCT/US2017/066815 WO2018112407A1 (en) | 2016-12-15 | 2017-12-15 | Antibodies and methods for depleting regulatory b10 cells and use in combination with immune checkpoint inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022189027A Division JP2023026426A (ja) | 2016-12-15 | 2022-11-28 | 制御性ｂ１０細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020502147A JP2020502147A (ja) | 2020-01-23 |
| JP2020502147A5 true JP2020502147A5 (enExample) | 2021-02-04 |
| JP7252627B2 JP7252627B2 (ja) | 2023-04-05 |
Family
ID=62559412
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531988A Active JP7252627B2 (ja) | 2016-12-15 | 2017-12-15 | 制御性ｂ１０細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用 |
| JP2022189027A Pending JP2023026426A (ja) | 2016-12-15 | 2022-11-28 | 制御性ｂ１０細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022189027A Pending JP2023026426A (ja) | 2016-12-15 | 2022-11-28 | 制御性ｂ１０細胞を枯渇させる抗体および方法並びに免疫チェックポイント阻害剤との併用における使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11230598B2 (enExample) |
| EP (1) | EP3554515A4 (enExample) |
| JP (2) | JP7252627B2 (enExample) |
| CN (1) | CN110248668B (enExample) |
| WO (1) | WO2018112407A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| WO2018112407A1 (en) * | 2016-12-15 | 2018-06-21 | Duke University | Antibodies and methods for depleting regulatory b10 cells and use in combination with immune checkpoint inhibitors |
| US11731955B2 (en) | 2018-06-25 | 2023-08-22 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Crystal habit of quinoline derivative and preparation method for crystalline powder thereof |
| WO2020183245A2 (en) * | 2019-03-11 | 2020-09-17 | Janssen Pharmaceutica Nv | ANTI-Vβ17/ANTI-CD123 BISPECIFIC ANTIBODIES |
| CN114901310A (zh) * | 2019-12-24 | 2022-08-12 | 尼尔路金治疗公司 | 使用il-2受体激动剂和免疫检查点抑制剂的组合疗法 |
| EP4204008A1 (en) * | 2020-08-26 | 2023-07-05 | Citius Pharmaceuticals, Inc. | Combination for use in methods of treating cancer |
| WO2022056192A1 (en) | 2020-09-11 | 2022-03-17 | Janssen Biotech, Inc. | Methods and compositions for modulating beta chain mediated immunity |
| US20240067747A1 (en) * | 2021-01-13 | 2024-02-29 | Shanghai Huaota Biopharmaceutical Co., Ltd. | Cd73-binding protein and use thereof |
| WO2022166876A1 (zh) * | 2021-02-03 | 2022-08-11 | 江苏先声药业有限公司 | 特异性识别磷脂酰肌醇蛋白聚糖3的单克隆抗体及其应用 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5298614A (en) | 1986-01-06 | 1994-03-29 | Nippon Shinyaku Co. Ltd. | Size limited double stranded poly I poly(cytidylate/4-thiouridylate) |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5484892A (en) | 1993-05-21 | 1996-01-16 | Dana-Farber Cancer Institute, Inc. | Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells |
| CA2195557C (en) | 1994-08-12 | 2006-10-17 | Shui-On Leung | Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells |
| EP0888125B1 (en) | 1996-03-20 | 2004-05-26 | Immunomedics, Inc. | GLYCOSYLATED IgG ANTIBODIES |
| US6183744B1 (en) | 1997-03-24 | 2001-02-06 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| ATE299885T1 (de) | 1999-02-15 | 2005-08-15 | Nippon Shinyaku Co Ltd | Polynukleotide mit gekürzter kette und verfahren zu ihrer herstellung |
| WO2001097843A2 (en) | 2000-06-22 | 2001-12-27 | University Of Iowa Research Foundation | Methods for enhancing antibody-induced cell lysis and treating cancer |
| EP1299115A2 (en) | 2000-06-26 | 2003-04-09 | Maxygen, Inc. | Methods and compositions for developing spore display systems for medicinal and industrial applications |
| WO2003072736A2 (en) | 2002-02-21 | 2003-09-04 | Duke University | Reagents and treatment methods for autoimmune diseases |
| US20040265315A1 (en) | 2002-09-05 | 2004-12-30 | Christine Dingivan | Methods of preventing or treating T cell malignancies by administering CD2 antagonists |
| NZ540555A (en) | 2002-11-15 | 2008-04-30 | Genmab As | Antibody therapeutics for treatingand/or preventing diseases associated with cells expressing CD25, including autoimmune diseases, inflammatory and hyperproliferative skin disorders |
| WO2004053452A2 (en) | 2002-12-11 | 2004-06-24 | 3M Innovative Properties Company | Assays relating to toll-like receptor activity |
| WO2004053057A2 (en) | 2002-12-11 | 2004-06-24 | 3M Innovative Properties Company | Gene expression systems and recombinant cell lines |
| WO2004094671A2 (en) | 2003-04-22 | 2004-11-04 | Coley Pharmaceutical Gmbh | Methods and products for identification and assessment of tlr ligands |
| WO2005000901A2 (en) | 2003-05-09 | 2005-01-06 | Duke University | Cd20-specific antibodies and methods of employing same |
| US20060120997A1 (en) | 2004-10-29 | 2006-06-08 | Biomune, Inc. | Cancer therapeutic compositions |
| WO2006054129A1 (en) | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
| US20060263357A1 (en) | 2005-05-05 | 2006-11-23 | Tedder Thomas F | Anti-CD19 antibody therapy for autoimmune disease |
| AU2007223903B2 (en) | 2006-03-06 | 2013-09-05 | Medimmune, Llc | Humanized anti-CD22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease |
| TWI423814B (zh) | 2006-09-01 | 2014-01-21 | Genticel | 用於引發特異性細胞毒性ｔ淋巴細胞（ｃｔｌ）反應之組成物，包含一淋巴去除性化合物以及一含有抗原序列且以專業化抗原呈現細胞為標靶之分子 |
| RU2009111884A (ru) * | 2006-09-01 | 2010-10-10 | Займоджинетикс, Инк. (Us) | Последовательности вариабельных областей моноклональных антител против il-31 и способы использования |
| US20090074711A1 (en) | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
| AU2007317333A1 (en) | 2006-11-02 | 2008-05-15 | Seattle Genetics, Inc. | Methods of treating neoplastic, autoimmune and inflammatory diseases |
| WO2009018500A1 (en) | 2007-07-31 | 2009-02-05 | The Johns Hopkins University | Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders |
| JP2011510654A (ja) | 2008-01-28 | 2011-04-07 | トーマス・ジェファーソン・ユニバーシティ | 有用な抗体を発現する雑種細胞の作成方法 |
| US9669057B2 (en) * | 2008-04-25 | 2017-06-06 | Duke University | Regulatory B cells and their uses |
| MY160126A (en) | 2009-05-13 | 2017-02-28 | Genzyme Corp | Anti-human cd52 immunoglobulins |
| SI2400298T1 (sl) | 2010-05-28 | 2013-11-29 | F. Hoffmann-La Roche Ag | Postopek kultivacije posamezne B-celice in izdelava specifičnih protiteles |
| CA3007787C (en) | 2010-06-03 | 2020-03-10 | Pharmacyclics Llc | The use of inhibitors of bruton's tyrosine kinase (btk) |
| EP2600878A4 (en) * | 2010-08-04 | 2014-06-11 | Univ Duke | REGULATORY B-CELLS AND ITS USES |
| US9814740B2 (en) | 2010-12-21 | 2017-11-14 | Duke University | Methods and compositions combining immunotherapy with monocyte activation |
| US20140212425A1 (en) * | 2011-12-05 | 2014-07-31 | Immunomedics, Inc. | Therapeutic use of anti-cd22 antibodies for inducing trogocytosis |
| US10017739B2 (en) | 2012-09-06 | 2018-07-10 | Duke University | Methods of expanding and assessing B cells and using expanded B cells to treat disease |
| TWI595006B (zh) * | 2014-12-09 | 2017-08-11 | 禮納特神經系統科學公司 | 抗ｐｄ－１抗體類和使用彼等之方法 |
| IL303972A (en) * | 2015-04-08 | 2023-08-01 | Novartis Ag | CD20 treatments, CD22 treatments and combined treatments with CD19 chimeric antigen receptor expressing cell |
| WO2018112407A1 (en) * | 2016-12-15 | 2018-06-21 | Duke University | Antibodies and methods for depleting regulatory b10 cells and use in combination with immune checkpoint inhibitors |
-
2017
- 2017-12-15 WO PCT/US2017/066815 patent/WO2018112407A1/en not_active Ceased
- 2017-12-15 EP EP17880656.8A patent/EP3554515A4/en not_active Withdrawn
- 2017-12-15 CN CN201780085237.6A patent/CN110248668B/zh not_active Expired - Fee Related
- 2017-12-15 JP JP2019531988A patent/JP7252627B2/ja active Active
-
2019
- 2019-06-14 US US16/441,917 patent/US11230598B2/en not_active Expired - Fee Related
-
2022
- 2022-11-28 JP JP2022189027A patent/JP2023026426A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020502147A5 (enExample) | ||
| JP2019500892A5 (enExample) | ||
| FI3823664T3 (fi) | Bispesifisiä anti-BCMA- x anti-CD3-vasta-aineita ja niiden käyttöjä | |
| JP2019513725A5 (enExample) | ||
| JP2019500891A5 (enExample) | ||
| CN110248668B (zh) | 用于消耗调节性b10细胞的抗体和方法以及与免疫检查点抑制剂的联用 | |
| RU2016131170A (ru) | Способы и композиции для лечения персистирующих инфекций | |
| JP2019529373A5 (ja) | 抗Ｔｉｍ−３抗体 | |
| JP2016533763A5 (ja) | ヒトｐｄ−１に特異的に結合する抗体抗原結合ドメインおよびそれを含む医薬組成物 | |
| RU2016107426A (ru) | Комбинирование агонистов cd27 и ингибирование иммунных контрольных точек для стимуляции иммунитета | |
| RU2018135247A (ru) | БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА К CD25 И Fc ГАММА-РЕЦЕПТОРУ ДЛЯ ЭЛИМИНАЦИИ ОПУХОЛЕСПЕЦИФИЧЕСКИХ КЛЕТОК | |
| JP2021518103A5 (enExample) | ||
| JP2017535257A5 (enExample) | ||
| PH12020551173A1 (en) | Anti-pd-l1 antibodies and uses thereof | |
| IL318482A (en) | Pd-1 inhibitor for use in a method of treating skin cancer | |
| FI3394103T3 (fi) | Anti-PD-1-vasta-aineiden ja bispesifisten anti-CD20-/anti-CD3-vasta-aineiden yhdistelmä syövän hoitoon | |
| JPWO2019246514A5 (enExample) | ||
| RU2021121771A (ru) | Cd20 терапия, cd22 терапия и комбинированная терапия клетками, экспрессирующими химерный антигенный рецептор (car) к cd19 | |
| JP2018035138A5 (enExample) | ||
| RU2017105118A (ru) | Нейтрализация ингибирующих путей в лимфоцитах | |
| RU2018126297A (ru) | Антитела, нацеленные на cd32b, и способы их применения | |
| JP2016531907A5 (enExample) | ||
| JP2017501157A5 (enExample) | ||
| JP2018501197A5 (enExample) | ||
| IL253462B (en) | Cancer treatment with monoclonal antibodies against latency-associated peptide |