JP2019513725A5 - - Google Patents
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- JP2019513725A5 JP2019513725A5 JP2018552062A JP2018552062A JP2019513725A5 JP 2019513725 A5 JP2019513725 A5 JP 2019513725A5 JP 2018552062 A JP2018552062 A JP 2018552062A JP 2018552062 A JP2018552062 A JP 2018552062A JP 2019513725 A5 JP2019513725 A5 JP 2019513725A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- pharmaceutical composition
- binds
- immune checkpoint
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1605947.9 | 2016-04-07 | ||
| GB201605947 | 2016-04-07 | ||
| PCT/EP2017/056469 WO2017174331A1 (en) | 2016-04-07 | 2017-03-17 | Anti cd25 fc gamma receptor bispecific antibodies for tumor specific cell depletion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019513725A JP2019513725A (ja) | 2019-05-30 |
| JP2019513725A5 true JP2019513725A5 (enExample) | 2020-04-23 |
| JP7325959B2 JP7325959B2 (ja) | 2023-08-15 |
Family
ID=58358618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552062A Active JP7325959B2 (ja) | 2016-04-07 | 2017-03-17 | 腫瘍特異的細胞の枯渇のための抗ＣＤ２５ ＦＣγ受容体二重特異性抗体 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20190135925A1 (enExample) |
| EP (1) | EP3440109B1 (enExample) |
| JP (1) | JP7325959B2 (enExample) |
| KR (2) | KR20220032642A (enExample) |
| CN (1) | CN109476739A (enExample) |
| AU (1) | AU2017247880B2 (enExample) |
| BR (1) | BR112018070636A2 (enExample) |
| CA (1) | CA3020204A1 (enExample) |
| CL (2) | CL2018002828A1 (enExample) |
| ES (1) | ES3046543T3 (enExample) |
| IL (1) | IL262129B2 (enExample) |
| MX (1) | MX2018012319A (enExample) |
| PL (1) | PL3440109T3 (enExample) |
| RU (1) | RU2759970C2 (enExample) |
| WO (1) | WO2017174331A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11371066B2 (en) | 2015-07-13 | 2022-06-28 | Modular Genetics, Inc. | Generation of acyl alcohols |
| KR20220032642A (ko) | 2016-04-07 | 2022-03-15 | 캔써 리서치 테크놀로지 리미티드 | 종양 특이적 세포 고갈을 위한 항 cd25 fc 감마 수용체 이중특이적 항체 |
| KR102576042B1 (ko) | 2016-10-11 | 2023-09-07 | 아게누스 인코포레이티드 | 항-lag-3 항체 및 이의 사용 방법 |
| US11879014B2 (en) | 2017-03-17 | 2024-01-23 | Tusk Therapeutics Ltd. | Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody |
| BR112019025188A2 (pt) | 2017-06-01 | 2020-06-23 | Cytomx Therapeutics, Inc. | Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos |
| GB201712032D0 (en) * | 2017-07-26 | 2017-09-06 | Bioinvent Int Ab | Antibodies and uses thereof |
| KR20200108286A (ko) * | 2018-01-10 | 2020-09-17 | 바이오인벤트 인터내셔날 에이비 | 신규한 항체 조합 및 용도 |
| CA3091181A1 (en) * | 2018-02-13 | 2019-08-22 | Precision Biologics, Inc. | Methods and compositions for targeting treg cells |
| AU2019233576A1 (en) | 2018-03-13 | 2020-09-17 | Cancer Research Technology Limited | Anti-CD25 for tumour specific cell depletion |
| EP3566718A1 (en) * | 2018-05-07 | 2019-11-13 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | A pharmazeutical combination (treg depleting agent, checkpoint inhibitor, tlr9 agonist) for use in the treatment of cancer |
| US20220213225A1 (en) * | 2018-07-30 | 2022-07-07 | Invenra Inc. | Multispecific treg binding molecules |
| CN113272330B (zh) * | 2019-03-02 | 2024-07-26 | 南通壹宸生物医药科技有限公司 | 一种双特异抗体 |
| WO2021145946A1 (en) * | 2020-01-13 | 2021-07-22 | Invenra Inc. | Multispecific treg binding molecules |
| EP4103611B1 (en) * | 2020-02-13 | 2024-03-27 | UCB Biopharma SRL | Bispecific antibodies binding hvem and cd9 |
| US20230174670A1 (en) | 2020-05-14 | 2023-06-08 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Anti-cd25 antibodies, antigen-binding fragments thereof, and medical uses thereof |
| AU2021378308B2 (en) * | 2020-11-13 | 2026-01-08 | Ibio, Inc. | Cd25 antibodies |
| EP4255929A2 (en) | 2020-12-02 | 2023-10-11 | Vib Vzw | An ltbr agonist in combination therapy against cancer |
| EP4396230A1 (en) | 2021-09-02 | 2024-07-10 | F. Hoffmann-La Roche AG | Antibodies for the treatment of aml |
| TW202336033A (zh) * | 2022-03-07 | 2023-09-16 | 瑞典商生物創新國際有限公司 | 抗體之新穎組合及用途 |
| CN119095621A (zh) | 2022-04-26 | 2024-12-06 | 弗哈夫曼拉罗切有限公司 | 用于治疗癌症的包括Fas轴拮抗剂和T-reg细胞消耗剂拮抗剂的联合疗法 |
| WO2023245021A2 (en) * | 2022-06-14 | 2023-12-21 | Invenra Inc. | Multispecific binding agents that target cd25 and/or ctla4 and uses thereof |
| WO2024088987A1 (en) | 2022-10-26 | 2024-05-02 | F. Hoffmann-La Roche Ag | Combination therapy for the treatment of cancer |
| WO2024151091A1 (ko) * | 2023-01-11 | 2024-07-18 | 한국과학기술원 | 종양 내 treg의 바이오마커를 포함하는 진단용 조성물 및 약학 조성물 |
| EP4662238A1 (en) | 2023-02-06 | 2025-12-17 | F. Hoffmann-La Roche AG | Combination therapy and uses thereof |
| CN120917143A (zh) | 2023-03-29 | 2025-11-07 | 第一三共株式会社 | 抗cd25抗体及抗cd25抗体-药物偶联物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1578397B1 (en) * | 2002-11-15 | 2012-12-26 | Genmab A/S | Human monoclonal antibodies against cd25 |
| GB0507696D0 (en) | 2005-04-15 | 2005-05-25 | Novartis Ag | Organic compounds |
| US20090304711A1 (en) * | 2006-09-20 | 2009-12-10 | Drew Pardoll | Combinatorial Therapy of Cancer and Infectious Diseases with Anti-B7-H1 Antibodies |
| CN102149820B (zh) | 2008-09-12 | 2014-07-23 | 国立大学法人三重大学 | 能够表达外源gitr配体的细胞 |
| EP2970486B1 (en) | 2013-03-15 | 2018-05-16 | Xencor, Inc. | Modulation of t cells with bispecific antibodies and fc fusions |
| US10227411B2 (en) * | 2015-03-05 | 2019-03-12 | Xencor, Inc. | Modulation of T cells with bispecific antibodies and FC fusions |
| KR20220032642A (ko) | 2016-04-07 | 2022-03-15 | 캔써 리서치 테크놀로지 리미티드 | 종양 특이적 세포 고갈을 위한 항 cd25 fc 감마 수용체 이중특이적 항체 |
| GB201712032D0 (en) * | 2017-07-26 | 2017-09-06 | Bioinvent Int Ab | Antibodies and uses thereof |
| AU2019233576A1 (en) * | 2018-03-13 | 2020-09-17 | Cancer Research Technology Limited | Anti-CD25 for tumour specific cell depletion |
| CN119095621A (zh) * | 2022-04-26 | 2024-12-06 | 弗哈夫曼拉罗切有限公司 | 用于治疗癌症的包括Fas轴拮抗剂和T-reg细胞消耗剂拮抗剂的联合疗法 |
-
2017
- 2017-03-17 KR KR1020227006876A patent/KR20220032642A/ko not_active Ceased
- 2017-03-17 US US16/091,350 patent/US20190135925A1/en not_active Abandoned
- 2017-03-17 MX MX2018012319A patent/MX2018012319A/es unknown
- 2017-03-17 CN CN201780022552.4A patent/CN109476739A/zh active Pending
- 2017-03-17 ES ES17711664T patent/ES3046543T3/es active Active
- 2017-03-17 IL IL262129A patent/IL262129B2/en unknown
- 2017-03-17 EP EP17711664.7A patent/EP3440109B1/en active Active
- 2017-03-17 RU RU2018135247A patent/RU2759970C2/ru active
- 2017-03-17 KR KR1020187032183A patent/KR20190017735A/ko not_active Ceased
- 2017-03-17 BR BR112018070636-1A patent/BR112018070636A2/pt not_active Application Discontinuation
- 2017-03-17 AU AU2017247880A patent/AU2017247880B2/en active Active
- 2017-03-17 WO PCT/EP2017/056469 patent/WO2017174331A1/en not_active Ceased
- 2017-03-17 PL PL17711664.7T patent/PL3440109T3/pl unknown
- 2017-03-17 JP JP2018552062A patent/JP7325959B2/ja active Active
- 2017-03-17 CA CA3020204A patent/CA3020204A1/en active Pending
-
2018
- 2018-10-04 CL CL2018002828A patent/CL2018002828A1/es unknown
-
2019
- 2019-11-29 CL CL2019003498A patent/CL2019003498A1/es unknown
-
2022
- 2022-03-28 US US17/706,028 patent/US20230265200A1/en active Pending
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