ES2557769T3 - Anticuerpos contra el antígeno del dominio de inmunoglobulina de células T y el dominio 1 de mucina (TIM-1) y usos de los mismos - Google Patents
Anticuerpos contra el antígeno del dominio de inmunoglobulina de células T y el dominio 1 de mucina (TIM-1) y usos de los mismos Download PDFInfo
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- ES2557769T3 ES2557769T3 ES04757910.7T ES04757910T ES2557769T3 ES 2557769 T3 ES2557769 T3 ES 2557769T3 ES 04757910 T ES04757910 T ES 04757910T ES 2557769 T3 ES2557769 T3 ES 2557769T3
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Classifications
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- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/622—Single chain antibody (scFv)
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Landscapes
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Applications Claiming Priority (3)
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| US45665203P | 2003-03-19 | 2003-03-19 | |
| US456652P | 2003-03-19 | ||
| PCT/US2004/008502 WO2004084823A2 (en) | 2003-03-19 | 2004-03-19 | Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof |
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| ES2557769T3 true ES2557769T3 (es) | 2016-01-28 |
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| ES (1) | ES2557769T3 (enExample) |
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| EP1401869B1 (en) | 2001-06-01 | 2007-12-26 | Biogen Idec MA Inc. | Molecules and methods for inhibiting shedding of kim-1 |
| US8709412B2 (en) | 2001-06-29 | 2014-04-29 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of TIM receptor activity in combination with cytoreductive therapy |
| US7658924B2 (en) * | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| ES2369542T3 (es) | 2002-07-31 | 2011-12-01 | Seattle Genetics, Inc. | Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa. |
| NZ605429A (en) * | 2002-09-06 | 2014-08-29 | Amgen Inc | Therapeutic human anti-il-1r1 monoclonal antibody |
| EP2025345A1 (en) | 2002-12-30 | 2009-02-18 | Biogen Idec MA Inc. | KIM-1 antagonists and use to modulate immune system |
| DK1613750T3 (en) | 2003-03-19 | 2016-01-18 | Amgen Fremont Inc | ANTIBODIES TO T CELL AND MUCINDO immunoglobulin-binding domain 1 (TIM-1) antigen and uses thereof |
| US7736644B2 (en) * | 2003-06-27 | 2010-06-15 | Amgen Fremont Inc. | Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof |
| AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| ES2456325T3 (es) | 2003-11-06 | 2014-04-22 | Seattle Genetics, Inc. | Compuestos de monometilvalina capaces de conjugación con ligandos |
| AU2005322410B2 (en) * | 2004-11-30 | 2011-11-10 | Amgen Fremont Inc. | Antibodies directed to GPNMB and uses thereof |
| EP2251037B1 (en) * | 2005-03-02 | 2015-01-14 | Biogen Idec MA Inc. | KIM-1 antibodies for treatment of TH1/TH2-mediated conditions |
| EP1858545A2 (en) * | 2005-03-04 | 2007-11-28 | Curedm Inc. | Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions |
| US20090142338A1 (en) * | 2005-03-04 | 2009-06-04 | Curedm, Inc. | Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions |
| CA2609667C (en) * | 2005-05-25 | 2011-02-22 | Curedm, Inc. | Human proislet peptide, derivatives and analogs thereof, and methods of using same |
| AU2013206293B2 (en) * | 2005-11-10 | 2016-05-19 | Curagen Corporation | Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen |
| EP2548583A3 (en) * | 2005-11-10 | 2013-02-27 | Curagen Corporation | Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen |
| WO2008064306A2 (en) * | 2006-11-22 | 2008-05-29 | Curedm, Inc. | Methods and compositions relating to islet cell neogenesis |
| CL2008002083A1 (es) | 2007-07-16 | 2008-11-21 | Genentech Inc | Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico |
| SI2474557T1 (sl) | 2007-07-16 | 2014-12-31 | Genentech, Inc. | Protiteles proti CD79b in imunokonjugati in postopki za uporabo |
| HRP20150330T1 (hr) * | 2007-08-30 | 2015-06-19 | Curedm Group Holdings, Llc | Pripravci i postupci uporabe prostaniäśnog peptida za stanice otoäśiä†a i njegovih analoga |
| WO2009064290A1 (en) * | 2007-11-13 | 2009-05-22 | Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services | Structure of tim family members |
| RS54883B1 (sr) | 2008-01-31 | 2016-10-31 | Genentech Inc | Anti-cd79b antitela i imunokonjugati i metode upotrebe |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| US20130156784A1 (en) * | 2008-08-20 | 2013-06-20 | Michael Jeffers | Compositions Using Antibodies Directed To GPNMB And Uses Thereof |
| WO2010135547A1 (en) * | 2009-05-20 | 2010-11-25 | Celldex Therapeutics, Inc. | Antibodies directed to gpnmb and uses thereof |
| AU2012316859A1 (en) * | 2011-09-29 | 2014-04-17 | Apo-T B.V. | Multi-specific binding molecules targeting aberrant cells |
| EP2802356A1 (en) | 2012-01-13 | 2014-11-19 | Apo-T B.V. | Aberrant cell-restricted immunoglobulins provided with a toxic moiety |
| WO2014018464A1 (en) * | 2012-07-23 | 2014-01-30 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of sepsis |
| RS60349B8 (sr) | 2014-09-23 | 2022-10-31 | Hoffmann La Roche | Postupak upotrebe anti-cd79b imunokonjugata |
| JP6709215B2 (ja) | 2014-10-27 | 2020-06-10 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 抗ｔｉｍ−３抗体 |
| GB201419094D0 (en) | 2014-10-27 | 2014-12-10 | Agency Science Tech & Res | Anti-TIM-3-antibodies |
| GB201419084D0 (en) | 2014-10-27 | 2014-12-10 | Agency Science Tech & Res | Anti-PD-1 antibodies |
| US20180044429A1 (en) | 2015-03-09 | 2018-02-15 | Celldex Therapeutics, Inc. | Cd27 agonists |
| US20200140851A1 (en) * | 2016-08-23 | 2020-05-07 | The Scripps Research Institute | Methods and Compositions Related to In Vivo Selection of Functional Molecules |
| JP7303749B2 (ja) * | 2017-01-13 | 2023-07-05 | セルダラ メディカル、エルエルシー | Ｔｉｍ－１を標的とするキメラ抗原受容体 |
| RU2674894C2 (ru) * | 2017-01-30 | 2018-12-13 | Общество с ограниченной ответственностью "ПЛАНТА" | Новые люциферазы и способы их использования |
| CN109265549A (zh) * | 2018-09-25 | 2019-01-25 | 中国人民解放军军事科学院军事医学研究院 | 一种具有中和活性的抗人Tim-1抗体 |
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| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
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-
2004
- 2004-03-19 DK DK04757910.7T patent/DK1613750T3/en active
- 2004-03-19 AU AU2004224390A patent/AU2004224390A1/en not_active Abandoned
- 2004-03-19 US US10/805,177 patent/US8067544B2/en not_active Expired - Fee Related
- 2004-03-19 JP JP2006507388A patent/JP2007525434A/ja active Pending
- 2004-03-19 ES ES04757910.7T patent/ES2557769T3/es not_active Expired - Lifetime
- 2004-03-19 EP EP15189243.7A patent/EP3000886A1/en not_active Withdrawn
- 2004-03-19 CA CA2519528A patent/CA2519528C/en not_active Expired - Fee Related
- 2004-03-19 EP EP04757910.7A patent/EP1613750B1/en not_active Expired - Lifetime
- 2004-03-19 WO PCT/US2004/008502 patent/WO2004084823A2/en not_active Ceased
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2010
- 2010-10-07 AU AU2010227016A patent/AU2010227016A1/en not_active Abandoned
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2011
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- 2011-11-29 US US13/305,898 patent/US9580503B2/en not_active Expired - Fee Related
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2014
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2016
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2017
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| Publication number | Publication date |
|---|---|
| AU2004224390A1 (en) | 2004-10-07 |
| EP1613750A4 (en) | 2008-06-25 |
| JP2007525434A (ja) | 2007-09-06 |
| EP3000886A1 (en) | 2016-03-30 |
| US20170218067A1 (en) | 2017-08-03 |
| WO2004084823A3 (en) | 2005-09-15 |
| CA2519528C (en) | 2016-01-26 |
| WO2004084823A2 (en) | 2004-10-07 |
| JP2014144971A (ja) | 2014-08-14 |
| US9580503B2 (en) | 2017-02-28 |
| JP2012001561A (ja) | 2012-01-05 |
| JP6103801B2 (ja) | 2017-03-29 |
| AU2010227016A1 (en) | 2010-10-28 |
| US8067544B2 (en) | 2011-11-29 |
| EP1613750B1 (en) | 2015-10-14 |
| US20050084449A1 (en) | 2005-04-21 |
| US20120251555A1 (en) | 2012-10-04 |
| JP2017048240A (ja) | 2017-03-09 |
| DK1613750T3 (en) | 2016-01-18 |
| CA2519528A1 (en) | 2004-10-07 |
| EP1613750A2 (en) | 2006-01-11 |
| JP2018150305A (ja) | 2018-09-27 |
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