JP2019535670A5 - - Google Patents

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Publication number
JP2019535670A5
JP2019535670A5 JP2019521046A JP2019521046A JP2019535670A5 JP 2019535670 A5 JP2019535670 A5 JP 2019535670A5 JP 2019521046 A JP2019521046 A JP 2019521046A JP 2019521046 A JP2019521046 A JP 2019521046A JP 2019535670 A5 JP2019535670 A5 JP 2019535670A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
binding
antibody
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JP2019521046A
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English (en)
Japanese (ja)
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JP2019535670A (ja
JP7231158B2 (ja
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Priority claimed from PCT/CA2017/051245 external-priority patent/WO2018072025A1/en
Publication of JP2019535670A publication Critical patent/JP2019535670A/ja
Publication of JP2019535670A5 publication Critical patent/JP2019535670A5/ja
Application granted granted Critical
Publication of JP7231158B2 publication Critical patent/JP7231158B2/ja
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JP2019521046A 2016-10-19 2017-10-19 Cd133結合剤およびその使用 Active JP7231158B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662410162P 2016-10-19 2016-10-19
US62/410,162 2016-10-19
US201762472209P 2017-03-16 2017-03-16
US62/472,209 2017-03-16
PCT/CA2017/051245 WO2018072025A1 (en) 2016-10-19 2017-10-19 Cd133-binding agents and uses thereof

Publications (3)

Publication Number Publication Date
JP2019535670A JP2019535670A (ja) 2019-12-12
JP2019535670A5 true JP2019535670A5 (enExample) 2020-11-26
JP7231158B2 JP7231158B2 (ja) 2023-03-01

Family

ID=62018307

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019521046A Active JP7231158B2 (ja) 2016-10-19 2017-10-19 Cd133結合剤およびその使用

Country Status (5)

Country Link
US (2) US11220551B2 (enExample)
EP (1) EP3529279A4 (enExample)
JP (1) JP7231158B2 (enExample)
CN (1) CN110352198B (enExample)
WO (1) WO2018072025A1 (enExample)

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SG11201908784TA (en) * 2017-03-27 2019-10-30 Hoffmann La Roche Improved antigen binding receptor formats
CN110526987A (zh) * 2018-05-25 2019-12-03 深圳宾德生物技术有限公司 靶向cd133的嵌合抗原受体、嵌合抗原受体t细胞及其制备方法和应用
CN109735500B (zh) * 2019-01-25 2023-05-16 苏州茂行生物科技有限公司 一种分泌型靶向cd133的car-t细胞及其制备方法和应用
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を予防するための方法および組成物
WO2020243479A1 (en) 2019-05-31 2020-12-03 The Johns Hopkins University Bispecific binding agents
EP3976649A4 (en) * 2019-05-31 2022-12-14 The Johns Hopkins University B-SPECIFIC IL-6Ra/IL-8R BINDING AGENTS TO BLOCK MIGRATION OF CANCER CELLS
CN113912696B (zh) * 2019-07-24 2023-05-30 暨南大学 靶向cd133的结合蛋白与其应用
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
CN111529690B (zh) * 2020-06-17 2023-03-31 中国科学院昆明动物研究所 人cd133蛋白1-108肽段的新用途
CN114057875B (zh) * 2020-07-31 2023-05-05 北京市神经外科研究所 抗cd133的单链抗体及其在制备治疗肿瘤的药物中的用途
CN116420076A (zh) * 2020-09-27 2023-07-11 基因泰克公司 高通量多参数免疫细胞接合物筛选测定
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
IL303269A (en) 2020-12-03 2023-07-01 Century Therapeutics Inc Genetically engineered cells and uses thereof
TW202241935A (zh) 2020-12-18 2022-11-01 美商世紀治療股份有限公司 具有可調適受體專一性之嵌合抗原受體系統
JP2024500189A (ja) 2020-12-21 2024-01-04 アロジーン セラピューティクス,インコーポレイテッド プロテアーゼ活性化cd45ゲートcar
MX2023008809A (es) 2021-01-29 2023-08-04 Allogene Therapeutics Inc ATENUACIÓN O INACTIVACIÓN DE UNO O MÁS DE TAP2, NLRC5, ß2M, TRAC, RFX5, RFXAP Y RFXANK PARA MITIGAR EL RECONOCIMIENTO DE CÉLULAS T DE PRODUCTOS CELULARES ALOGÉNICOS.
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
IL308809A (en) * 2021-06-04 2024-01-01 Amgen Res Munich Gmbh T cell binding compounds and their uses
CN114316050B (zh) * 2021-12-24 2022-11-11 北京市神经外科研究所 Cd133抗体、嵌合抗原受体及其应用
CN114213537B (zh) * 2021-12-24 2022-06-14 北京市神经外科研究所 Cd133抗体、嵌合抗原受体及其应用
US20250082777A1 (en) 2022-01-10 2025-03-13 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
US20240042030A1 (en) 2022-07-29 2024-02-08 Allogene Therapeutics, Inc. Engineered cells with reduced gene expression to mitigate immune cell recognition
WO2024040195A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
EP4602174A1 (en) 2022-10-13 2025-08-20 Sana Biotechnology, Inc. Viral particles targeting hematopoietic stem cells
WO2024119157A1 (en) 2022-12-02 2024-06-06 Sana Biotechnology, Inc. Lipid particles with cofusogens and methods of producing and using the same
WO2024220597A2 (en) 2023-04-18 2024-10-24 Sana Biotechnology, Inc. Digital droplet based assay for detecting replication competent lentiviral vector
AU2024274792A1 (en) 2023-05-23 2025-10-23 Sana Biotechnology, Inc. Tandem fusogens and related lipid particles
EP4719352A1 (en) 2023-05-31 2026-04-08 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2025056957A1 (en) * 2023-09-15 2025-03-20 Jimenez Mendoza, Dimas Peptide based medicines for treating cancer
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
KR20260105764A (ko) 2023-10-30 2026-07-07 알로젠 테라퓨틱스 인코포레이티드 조작된 세포
WO2025184529A1 (en) 2024-03-01 2025-09-04 Sana Biotechnology, Inc. Viral particles with fusogen display and related compositions and methods
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
CN118108849B (zh) * 2024-04-28 2024-06-25 苏州睿瀛生物技术有限公司 一种抗cd33的纳米抗体制备方法和抗体的荧光标记流式应用

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EP2065397A1 (en) * 2007-11-20 2009-06-03 Miltenyi Biotech GmbH. Method for the separation of cells
EP2769989A1 (en) * 2013-02-21 2014-08-27 Universitätsklinikum Freiburg Recombinant bispecific antibody that binds to the CD133 antigen on tumor cells and to the human CD3 T cell receptor
US10711068B2 (en) 2015-03-26 2020-07-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anti-CD133 monoclonal antibodies and related compositions and methods
CA2962157A1 (en) * 2016-10-19 2018-04-19 The Governing Council Of The University Of Toronto Cd133-binding agents and uses thereof

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