JP2018538281A5 - - Google Patents

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JP2018538281A5
JP2018538281A5 JP2018526853A JP2018526853A JP2018538281A5 JP 2018538281 A5 JP2018538281 A5 JP 2018538281A5 JP 2018526853 A JP2018526853 A JP 2018526853A JP 2018526853 A JP2018526853 A JP 2018526853A JP 2018538281 A5 JP2018538281 A5 JP 2018538281A5
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optionally substituted
optionally
alkyl
pharmaceutically acceptable
carbocyclyl
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JP2018538281A (ja
JP7385356B2 (ja
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JP2018526853A 2015-11-25 2016-11-23 二価ブロモドメインインヒビターおよびそれらの使用 Active JP7385356B2 (ja)

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JP2021193552A JP2022043073A (ja) 2015-11-25 2021-11-29 二価ブロモドメインインヒビターおよびそれらの使用

Applications Claiming Priority (7)

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US201562259797P 2015-11-25 2015-11-25
US62/259,797 2015-11-25
US201562261703P 2015-12-01 2015-12-01
US62/261,703 2015-12-01
US201662338968P 2016-05-19 2016-05-19
US62/338,968 2016-05-19
PCT/US2016/063502 WO2017091673A2 (en) 2015-11-25 2016-11-23 Bivalent bromodomain inhibtors and uses thereof

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JP2018538281A JP2018538281A (ja) 2018-12-27
JP2018538281A5 true JP2018538281A5 (enExample) 2020-01-16
JP7385356B2 JP7385356B2 (ja) 2023-11-22

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JP2021193552A Abandoned JP2022043073A (ja) 2015-11-25 2021-11-29 二価ブロモドメインインヒビターおよびそれらの使用

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US (2) US10913752B2 (enExample)
EP (1) EP3380100A4 (enExample)
JP (2) JP7385356B2 (enExample)
KR (1) KR20180081809A (enExample)
CN (2) CN108472295B (enExample)
AU (2) AU2016361478B2 (enExample)
BR (1) BR112018009798A8 (enExample)
CA (1) CA3003288A1 (enExample)
CL (1) CL2018001404A1 (enExample)
CO (1) CO2018005370A2 (enExample)
CR (1) CR20180336A (enExample)
IL (1) IL258970A (enExample)
MX (1) MX2018006499A (enExample)
PE (1) PE20181298A1 (enExample)
PH (1) PH12018550070A1 (enExample)
RU (1) RU2742035C2 (enExample)
SG (2) SG10201913450PA (enExample)
WO (1) WO2017091673A2 (enExample)

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US12161648B2 (en) 2018-10-09 2024-12-10 The Regents Of The University Of California Covalent targeting of E3 ligases
CN110101705B (zh) * 2019-05-07 2022-01-14 河南农业大学 Bet家族蛋白抑制剂的抗病毒用途
AU2020360170A1 (en) * 2019-09-30 2022-05-19 Kyowa Kirin Co., Ltd. Bet degrader
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CN113679724B (zh) * 2020-05-18 2023-04-07 中国科学院微生物研究所 一种流感病毒小分子抑制剂
CN114276333B (zh) * 2020-09-28 2023-05-09 中国科学院上海药物研究所 二氢喹喔啉类溴结构域二价抑制剂
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