JP2018012698A5 - - Google Patents
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- JP2018012698A5 JP2018012698A5 JP2017145036A JP2017145036A JP2018012698A5 JP 2018012698 A5 JP2018012698 A5 JP 2018012698A5 JP 2017145036 A JP2017145036 A JP 2017145036A JP 2017145036 A JP2017145036 A JP 2017145036A JP 2018012698 A5 JP2018012698 A5 JP 2018012698A5
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- 238000000034 method Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8668708P | 2008-08-06 | 2008-08-06 | |
| US61/086,687 | 2008-08-06 | ||
| US15103609P | 2009-02-09 | 2009-02-09 | |
| US61/151,036 | 2009-02-09 | ||
| US17308809P | 2009-04-27 | 2009-04-27 | |
| US61/173,088 | 2009-04-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015093417A Division JP2015157843A (ja) | 2008-08-06 | 2015-04-30 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018012698A JP2018012698A (ja) | 2018-01-25 |
| JP2018012698A5 true JP2018012698A5 (enExample) | 2018-09-06 |
Family
ID=41129519
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522113A Active JP5984389B2 (ja) | 2008-08-06 | 2009-07-27 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
| JP2015093417A Pending JP2015157843A (ja) | 2008-08-06 | 2015-04-30 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
| JP2017145036A Pending JP2018012698A (ja) | 2008-08-06 | 2017-07-27 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522113A Active JP5984389B2 (ja) | 2008-08-06 | 2009-07-27 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
| JP2015093417A Pending JP2015157843A (ja) | 2008-08-06 | 2015-04-30 | ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤 |
Country Status (31)
| Country | Link |
|---|---|
| US (7) | US8012976B2 (enExample) |
| EP (3) | EP2767537B1 (enExample) |
| JP (3) | JP5984389B2 (enExample) |
| KR (1) | KR101846029B1 (enExample) |
| CN (3) | CN103896942A (enExample) |
| AR (1) | AR072970A1 (enExample) |
| AU (1) | AU2009279944B2 (enExample) |
| BR (1) | BRPI0917119B1 (enExample) |
| CA (1) | CA2732797C (enExample) |
| CY (3) | CY1115022T1 (enExample) |
| DK (2) | DK2767537T3 (enExample) |
| ES (2) | ES2625817T3 (enExample) |
| FR (1) | FR19C1071I2 (enExample) |
| GB (1) | GB2462361A (enExample) |
| HR (1) | HRP20170982T1 (enExample) |
| HU (2) | HUE035295T2 (enExample) |
| IL (1) | IL211070A (enExample) |
| LT (2) | LT2767537T (enExample) |
| LU (1) | LUC00140I2 (enExample) |
| MX (1) | MX2011001328A (enExample) |
| NL (1) | NL301021I2 (enExample) |
| NO (1) | NO2019042I1 (enExample) |
| NZ (1) | NZ591166A (enExample) |
| PL (2) | PL2767537T3 (enExample) |
| PT (2) | PT2767537T (enExample) |
| SG (2) | SG193842A1 (enExample) |
| SI (2) | SI2767537T1 (enExample) |
| SM (1) | SMT201700312T1 (enExample) |
| TW (2) | TWI448464B (enExample) |
| WO (1) | WO2010017055A2 (enExample) |
| ZA (1) | ZA201100897B (enExample) |
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| DK2533640T3 (en) * | 2010-02-08 | 2017-01-23 | Medivation Technologies Inc | METHODS OF SYNTHESIS OF DIHYDROPYRIDOPHTHALAZINE DERIVATIVES |
| WO2011130661A1 (en) * | 2010-04-16 | 2011-10-20 | Biomarin Pharmaceutical Inc. | Methods of using dihydropyridophthalazinone inhibitors of poly (adp-ribose)polymerase (parp) |
| EP2569313A1 (en) | 2010-05-12 | 2013-03-20 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
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| EP3878851A1 (en) | 2011-09-30 | 2021-09-15 | Vertex Pharmaceuticals Incorporated | Process for making compounds useful as inhibitors of atr kinase |
| RS56616B1 (sr) * | 2011-12-31 | 2018-02-28 | Beigene Ltd | Kondenzovani tetra ili penta-ciklični dihidrodiazepinokarbazoloni kao parp inhibitori |
| NZ626937A (en) * | 2011-12-31 | 2016-09-30 | Beigene Ltd | Fused tetra or penta-cyclic pyridophthalazinones as parp inhibitors |
| EP2804602B1 (en) | 2012-01-20 | 2024-12-04 | Del Mar Pharmaceuticals | Use of substituted hexitols including dianhydrogalactitol and analogs to treat neoplastic disease and cancer stem cells including glioblastoma multforme and medulloblastoma |
| PT2833973T (pt) | 2012-04-05 | 2017-12-21 | Vertex Pharma | Compostos úteis como inibidores da cinase atr e terapias de combinação dos mesmos |
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