|
US2830993A
(en)
|
|
1958-04-15 |
|
Quinolizine derivatives |
|
US2843591A
(en)
|
|
1958-07-15 |
|
Method for preparing same |
|
US2326643A
(en)
|
1941-08-20 |
1943-08-10 |
Rohm & Haas |
Complex polyamino sulphur compound
|
|
US3045021A
(en)
|
1959-09-24 |
1962-07-17 |
Hoffmann La Roche |
Preparation of substituted 2-oxobenzoquinolizines
|
|
GB999095A
(en)
*
|
1961-02-21 |
1965-07-21 |
Wellcome Found |
The preparation of quinolizine derivatives
|
|
HU175890B
(en)
|
1977-06-15 |
1980-11-28 |
Chinoin Gyogyszer Es Vegyeszet |
Process for producing new 1,2,3,4,6,7-hexahydro-11-b-alpha-benzo-square bracket-a-square brecket closed-quinolyzine derivatives
|
|
US4316897A
(en)
|
1980-09-10 |
1982-02-23 |
Hoffmann-La Roche Inc. |
Method of lowering serum prolactin
|
|
DE3407955A1
(de)
|
1984-03-03 |
1985-09-05 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Arzneimittel, enthaltend quartaere 3,4-dihydroisochinoliniumsalze
|
|
US5451409A
(en)
|
1993-11-22 |
1995-09-19 |
Rencher; William F. |
Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
|
|
ES2293638T3
(es)
|
1994-03-25 |
2008-03-16 |
Isotechnika, Inc. |
Mejora de la eficacia de farmacos por deuteracion.
|
|
US6221335B1
(en)
|
1994-03-25 |
2001-04-24 |
Isotechnika, Inc. |
Method of using deuterated calcium channel blockers
|
|
GB9817028D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Plc |
Novel compounds
|
|
US6440710B1
(en)
|
1998-12-10 |
2002-08-27 |
The Scripps Research Institute |
Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds
|
|
PT1104760E
(pt)
|
1999-12-03 |
2003-06-30 |
Pfizer Prod Inc |
Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios
|
|
EP1134290A3
(en)
|
2000-03-14 |
2004-01-02 |
Pfizer Products Inc. |
Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors
|
|
US6488962B1
(en)
|
2000-06-20 |
2002-12-03 |
Depomed, Inc. |
Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
|
|
US6287599B1
(en)
|
2000-12-20 |
2001-09-11 |
Shire Laboratories, Inc. |
Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles
|
|
CA2409552A1
(en)
|
2001-10-25 |
2003-04-25 |
Depomed, Inc. |
Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
|
|
TW200413273A
(en)
|
2002-11-15 |
2004-08-01 |
Wako Pure Chem Ind Ltd |
Heavy hydrogenation method of heterocyclic rings
|
|
EP1638529B1
(en)
|
2003-06-16 |
2016-08-10 |
ANDRX Pharmaceuticals, LLC. |
Oral extended-release composition
|
|
CA2546395A1
(en)
|
2003-11-21 |
2005-06-09 |
Memory Pharmaceutical Corporation |
Compositions and methods of treatment using l-type calcium channel blockers and cholinesterase inhibitors
|
|
US7367953B2
(en)
|
2003-11-26 |
2008-05-06 |
Ge Medical Systems Global Technology Company |
Method and system for determining a period of interest using multiple inputs
|
|
GB2410947B
(en)
|
2004-02-11 |
2008-09-17 |
Cambridge Lab Ltd |
Pharmaceutical compounds
|
|
WO2006053067A2
(en)
|
2004-11-09 |
2006-05-18 |
Prestwick Pharmaceuticals, Inc. |
Combination of amantadine and a tetrabenazine compound for treating hyperkinetic disorders
|
|
AU2006206458B2
(en)
|
2005-01-19 |
2012-10-25 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
|
CA2613631A1
(en)
|
2005-06-23 |
2007-01-04 |
Spherics, Inc. |
Improved dosage forms for movement disorder treatment
|
|
US20080033011A1
(en)
|
2005-07-29 |
2008-02-07 |
Concert Pharmaceuticals Inc. |
Novel benzo[d][1,3]-dioxol derivatives
|
|
US7750168B2
(en)
|
2006-02-10 |
2010-07-06 |
Sigma-Aldrich Co. |
Stabilized deuteroborane-tetrahydrofuran complex
|
|
CA2642593C
(en)
|
2006-02-17 |
2014-11-04 |
Birds Pharma Gmbh Berolina Innovative Research & Development Services |
Deuterated catecholamine derivatives and medicaments comprising said compounds
|
|
CA2650904C
(en)
|
2006-05-02 |
2015-07-07 |
The Trustees Of The University Of Pennsylvania |
Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents
|
|
HU227610B1
(en)
|
2006-09-18 |
2011-09-28 |
Richter Gedeon Nyrt |
Pharmaceutical compositions containing rosuvastatin potassium
|
|
CA2665415A1
(en)
|
2006-10-12 |
2008-04-17 |
Novartis Ag |
Use of modified cyclosporins
|
|
EP2081929B1
(en)
*
|
2006-11-08 |
2013-01-09 |
Neurocrine Biosciences, Inc. |
Substituted 3-isobutyl-9, 10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2-ol compounds and methods relating thereto
|
|
ATE540041T1
(de)
|
2006-11-21 |
2012-01-15 |
Rigel Pharmaceuticals Inc |
Prodrug-salze von 2,4-pyrimidindiaminverbindungen und anwendungen davon
|
|
WO2008112278A2
(en)
|
2007-03-12 |
2008-09-18 |
The Trustees Of Columbia University In The City Of New York |
Methods and compositions for modulating insulin secretion and glucose metabolism
|
|
US8008500B2
(en)
|
2007-06-08 |
2011-08-30 |
General Electric Company |
Intermediates useful for making tetrabenazine compounds
|
|
US9827210B2
(en)
|
2007-06-29 |
2017-11-28 |
Phovitreal Pty Ltd |
Treatment or prophylaxis of a neurological or neuropsychiatric disorders via ocular administration
|
|
US7902364B2
(en)
|
2007-11-29 |
2011-03-08 |
General Electric Company |
Alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes
|
|
US8053578B2
(en)
|
2007-11-29 |
2011-11-08 |
General Electric Company |
Alpha-fluoroalkyl dihydrotetrabenazine imaging agents and probes
|
|
WO2009124357A1
(en)
|
2008-04-10 |
2009-10-15 |
Malvin Leonard Eutick |
Fast dissolving oral formulations for critical drugs
|
|
US9012471B2
(en)
|
2008-04-11 |
2015-04-21 |
The Trustees Of Columbia University In The City Of New York |
Glucose metabolism modulating compounds
|
|
CN201204923Y
(zh)
|
2008-04-14 |
2009-03-11 |
云南省烟草公司昆明市公司 |
鲜烟叶编叶机
|
|
EP2318035B1
(en)
|
2008-07-01 |
2019-06-12 |
Curemark, Llc |
Methods and compositions for the treatment of symptoms of neurological and mental health disorders
|
|
DE102008040212A1
(de)
|
2008-07-07 |
2010-01-14 |
Zf Friedrichshafen Ag |
Radaufhängung für ein Fahrzeug
|
|
GB2462611A
(en)
|
2008-08-12 |
2010-02-17 |
Cambridge Lab |
Pharmaceutical composition comprising tetrabenazine
|
|
WO2011019956A2
(en)
|
2009-08-12 |
2011-02-17 |
Biovail Laboratories International (Barbados) S.R.L. |
Pharmaceutical compositions
|
|
US20110053866A1
(en)
|
2008-08-12 |
2011-03-03 |
Biovail Laboratories International (Barbados) S.R.L. |
Pharmaceutical compositions
|
|
CA2972242A1
(en)
|
2008-09-18 |
2010-04-22 |
Auspex Pharmaceuticals, Inc. |
Benzoquinoline inhibitors of vesicular monoamine transporter 2
|
|
US20100113496A1
(en)
|
2008-09-25 |
2010-05-06 |
Auspex Pharmaceuticals, Inc. |
Piperidine modulators of vmat2
|
|
US20120053159A1
(en)
|
2009-02-11 |
2012-03-01 |
Muller George W |
Isotopologues of lenalidomide
|
|
JP4679658B2
(ja)
|
2009-10-10 |
2011-04-27 |
株式会社オーバル |
フィールド機器の光電センシング感度調整
|
|
CN102120742B
(zh)
|
2010-01-08 |
2013-03-13 |
中国药科大学 |
一种丁苯那嗪的制备方法
|
|
US20110206782A1
(en)
|
2010-02-24 |
2011-08-25 |
Auspex Pharmaceuticals, Inc. |
Piperidine modulators of dopamine receptor
|
|
EP2539347A2
(en)
|
2010-02-24 |
2013-01-02 |
Auspex Pharmaceuticals, Inc. |
Trimethoxyphenyl inhibitors of tyrosine kinase
|
|
EP3351247A1
(en)
|
2010-06-01 |
2018-07-25 |
Auspex Pharmaceutical, Inc. |
Benzoquinolone inhibitors of vmat2
|
|
WO2012006551A2
(en)
|
2010-07-08 |
2012-01-12 |
The Brigham And Women's Hospital, Inc. |
Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules
|
|
WO2012079022A1
(en)
|
2010-12-10 |
2012-06-14 |
Concert Pharmaceuticals, Inc. |
Substituted dioxopiperidinyl phthalimide derivatives
|
|
WO2012081031A1
(en)
|
2010-12-15 |
2012-06-21 |
Enaltec Labs Pvt. Ltd. |
Process for preparing tetrabenazine
|
|
CN102260255B
(zh)
|
2011-07-07 |
2013-07-10 |
江苏省原子医学研究所 |
一种9,10-二甲氧基-1,3,4,6,7,11b-六氢-3-异丁基-2H-苯并[a]喹嗪-2-酮的简便合成方法
|
|
WO2013061161A2
(en)
|
2011-10-28 |
2013-05-02 |
Green Bcn Consulting Services Sl |
New combination therapies for treating neurological disorders
|
|
KR101362482B1
(ko)
|
2012-01-31 |
2014-02-12 |
한국과학기술연구원 |
테트라베나진과 다이하이드로테트라베나진의 제조방법
|
|
US9901564B2
(en)
|
2012-03-23 |
2018-02-27 |
Cardero Therapeutics, Inc. |
Compounds and compositions for the treatment of muscular disorders
|
|
EP4345100A3
(en)
|
2012-09-18 |
2024-04-10 |
Auspex Pharmaceuticals, Inc. |
Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
|
|
CN102936246A
(zh)
*
|
2012-11-08 |
2013-02-20 |
江苏暨明医药科技有限公司 |
丁苯那嗪的合成方法
|
|
JP2016506957A
(ja)
|
2013-01-31 |
2016-03-07 |
オースペックス・ファーマシューティカルズ・インコーポレイテッドＡｕｓｐｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
Ｖｍａｔ２のベンゾキノロン阻害剤
|
|
WO2015048370A1
(en)
|
2013-09-27 |
2015-04-02 |
Auspex Pharmaceuticals, Inc. |
Benzoquinolone inhibitors of vmat2
|
|
WO2015077521A1
(en)
|
2013-11-22 |
2015-05-28 |
Auspex Pharmaceuticals, Inc. |
Benzoquinoline inhibitors of vesicular monoamine transporter 2
|
|
WO2015077520A1
(en)
|
2013-11-22 |
2015-05-28 |
Auspex Pharmaceuticals, Inc. |
Methods of treating abnormal muscular activity
|
|
WO2015084622A1
(en)
|
2013-12-03 |
2015-06-11 |
Auspex Pharmaceuticals, Inc. |
Methods of manufacturing benzoquinoline compounds
|
|
EP3398602A1
(en)
|
2014-01-27 |
2018-11-07 |
Auspex Pharmaceuticals, Inc. |
Benzoquinoline inhibitors of vesicular monoamine transporter 2
|