JP2015532645A5 - - Google Patents
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- Publication number
- JP2015532645A5 JP2015532645A5 JP2015528568A JP2015528568A JP2015532645A5 JP 2015532645 A5 JP2015532645 A5 JP 2015532645A5 JP 2015528568 A JP2015528568 A JP 2015528568A JP 2015528568 A JP2015528568 A JP 2015528568A JP 2015532645 A5 JP2015532645 A5 JP 2015532645A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- immunogenic carrier
- nhc
- conjugate
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 29
- 230000002163 immunogen Effects 0.000 claims 16
- 101000800130 Bos taurus Thyroglobulin Proteins 0.000 claims 4
- 108010058846 Ovalbumin Proteins 0.000 claims 4
- 108010045069 keyhole-limpet hemocyanin Proteins 0.000 claims 4
- 229940092253 ovalbumin Drugs 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691454P | 2012-08-21 | 2012-08-21 | |
| US61/691,454 | 2012-08-21 | ||
| PCT/US2013/055700 WO2014031587A1 (en) | 2012-08-21 | 2013-08-20 | Haptens of olanzipine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017130471A Division JP6423490B2 (ja) | 2012-08-21 | 2017-07-03 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015532645A JP2015532645A (ja) | 2015-11-12 |
| JP2015532645A5 true JP2015532645A5 (enExample) | 2016-05-26 |
| JP6171014B2 JP6171014B2 (ja) | 2017-07-26 |
Family
ID=49081007
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015528568A Active JP6171014B2 (ja) | 2012-08-21 | 2013-08-20 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
| JP2017130471A Active JP6423490B2 (ja) | 2012-08-21 | 2017-07-03 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
| JP2018196525A Active JP6763000B2 (ja) | 2012-08-21 | 2018-10-18 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017130471A Active JP6423490B2 (ja) | 2012-08-21 | 2017-07-03 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
| JP2018196525A Active JP6763000B2 (ja) | 2012-08-21 | 2018-10-18 | オランザピン（Ｏｌａｎｚｉｐｉｎｅ）のハプテン |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9303041B2 (enExample) |
| EP (2) | EP3492473B1 (enExample) |
| JP (3) | JP6171014B2 (enExample) |
| CN (1) | CN104854110B (enExample) |
| AU (1) | AU2013306018B2 (enExample) |
| CA (1) | CA2882454C (enExample) |
| ES (2) | ES3043017T3 (enExample) |
| PL (1) | PL2888269T3 (enExample) |
| PT (1) | PT2888269T (enExample) |
| TR (1) | TR201816378T4 (enExample) |
| WO (1) | WO2014031587A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104755093B (zh) | 2012-08-21 | 2018-11-16 | 詹森药业有限公司 | 奥氮平半抗原的抗体及其用途 |
| PT3663317T (pt) | 2012-08-21 | 2023-01-23 | Janssen Pharmaceutica Nv | Anticorpos para haptenos de quetiapina e sua utilização |
| EP3492473B1 (en) * | 2012-08-21 | 2025-07-30 | Janssen Pharmaceutica NV | Haptens of olanzapine |
| CN104755928B (zh) | 2012-08-21 | 2017-05-10 | 詹森药业有限公司 | 奥氮平的抗体及其用途 |
| ES2978909T3 (es) | 2012-08-21 | 2024-09-23 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de aripiprazol y uso de los mismos |
| WO2014031668A2 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to quetiapine and use thereof |
| TR201816416T4 (tr) | 2012-08-21 | 2018-11-21 | Janssen Pharmaceutica Nv | Risperidona yönelik antikorlar ve bunların kullanımı. |
| JP6374387B2 (ja) | 2012-08-21 | 2018-08-15 | ヤンセン ファーマシューティカ エヌ．ベー． | リスペリドンハプテンへの抗体及びその使用 |
| ES2822914T3 (es) | 2012-08-21 | 2021-05-05 | Janssen Pharmaceutica Nv | Haptenos de aripiprazol y su uso en inmunoensayos |
| ES2762105T3 (es) | 2012-08-21 | 2020-05-22 | Janssen Pharmaceutica Nv | Anticuerpos para aripiprazol y uso de los mismos |
| AU2013305965B2 (en) | 2012-08-21 | 2017-08-24 | Saladax Biomedical Inc. | Antibodies to paliperidone and use thereof |
| CA2882489A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc. | Antibodies to paliperidone haptens and use thereof |
| CN108431040B (zh) | 2015-12-17 | 2022-07-26 | 詹森药业有限公司 | 利培酮的抗体及其用途 |
| AU2016370853A1 (en) | 2015-12-17 | 2018-06-07 | Saladax Biomedical Inc. | Antibodies to quetiapine and use thereof |
| CN110950808A (zh) * | 2019-10-30 | 2020-04-03 | 杭州博拓生物科技股份有限公司 | 一种氯氮平人工抗原及其制备方法 |
| CN110938082A (zh) * | 2019-10-30 | 2020-03-31 | 杭州博拓生物科技股份有限公司 | 一种奥氮平人工抗原及其制备方法 |
| AU2021406283A1 (en) * | 2020-12-22 | 2023-06-22 | Intervet International B.V. | Conjugated zearalenone to protect against mycotoxicosis |
| CN114685527B (zh) * | 2020-12-25 | 2024-03-05 | 长沙博源医疗科技有限公司 | 一种奥氮平衍生物、免疫原、抗奥氮平特异性抗体及其制备方法与应用 |
| CN114685477B (zh) * | 2020-12-25 | 2023-11-17 | 长沙博源医疗科技有限公司 | 一种利奈唑胺衍生物、免疫原、抗利奈唑胺特异性抗体及其制备方法与应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022780A (en) | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| EP0582368B1 (en) * | 1992-05-29 | 2001-01-24 | Eli Lilly And Company Limited | Thienobenzodiazepine derivatives for treatment of CNS disorders |
| US6034078A (en) | 1992-05-29 | 2000-03-07 | Eli Lilly And Company Limited | Thienobenzodiazepine compounds |
| EP0576095B1 (en) * | 1992-06-26 | 1999-01-27 | Johnson & Johnson Clinical Diagnostics, Inc. | Immunoassays with labeled thyronine hapten analogues |
| US5395933A (en) * | 1992-08-07 | 1995-03-07 | Eastman Kodak Company | Carbamazepine hapten analogues |
| UA76708C2 (uk) * | 1999-12-08 | 2006-09-15 | Сінгента Патисипейшонс Аг | Антитіло, яке застосовується в імунологічному аналізі зразка для визначення неонікотиноїдного інсектициду, білковий кон'югат для одержання антитіла, спосіб визначення концентрації неонікотиноїдного інсектициду в зразку та набір для визначення кількості неонікотиноїдного інсектициду |
| US6958156B2 (en) | 2000-12-15 | 2005-10-25 | Vyrex Corporation | Isoflavone derivatives |
| ATE380818T1 (de) * | 2002-03-28 | 2007-12-15 | Lilly Co Eli | Piperazine-substituierte aryl-benzodiazepinen und ihre verwendung als dopaminrezeptor-antagonisten zur behandlung von psychose |
| ES2285227T3 (es) * | 2002-08-05 | 2007-11-16 | Eli Lilly And Company | Arilbenzodiazepinas sustituidas con piperazina. |
| EP1664007B1 (en) | 2003-09-23 | 2009-12-23 | Fermion Oy | Preparation of quetiapine |
| TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
| KR20070053214A (ko) * | 2004-08-26 | 2007-05-23 | 니콜라스 피라말 인디아 리미티드 | 신규 생분해성 링커를 함유하는 프로드럭 |
| MX2010003259A (es) | 2007-09-27 | 2010-04-12 | Novartis Ag | Ensayo de monitoreo de farmacos. |
| US20100069356A1 (en) | 2008-09-17 | 2010-03-18 | Auspex Pharmaceuticals, Inc. | Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors |
| WO2010043893A1 (en) | 2008-10-14 | 2010-04-22 | Astrazeneca Ab | Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections |
| EP2194048A1 (en) | 2008-12-02 | 2010-06-09 | Dirk Sartor | Nitrate esters for the treatment of vascular and metabolic diseases |
| CA2785846C (en) | 2009-12-31 | 2015-07-07 | Kempharm, Inc. | Amino acid conjugates of quetiapine, process for making and using the same |
| SI2544536T1 (sl) | 2010-03-11 | 2019-03-29 | Kempharm, Inc. | Maščobno kislinski konjugati kvetiapina proces za njih izdelavo in uporabo |
| US8088594B2 (en) | 2010-03-16 | 2012-01-03 | Saladax Biomedical Inc. | Risperidone immunoassay |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| US8623324B2 (en) | 2010-07-21 | 2014-01-07 | Aat Bioquest Inc. | Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates |
| JP5757497B2 (ja) * | 2010-10-06 | 2015-07-29 | 公立大学法人大阪府立大学 | シガトキシン類ｃｔｘ１ｂおよび５４−デオキシ−ｃｔｘ１ｂを認識するモノクローナル抗体およびそれを用いるシガトキシン類検出キット |
| WO2013088255A1 (en) * | 2011-12-15 | 2013-06-20 | Alkermes Pharma Ireland Limited | Prodrugs of secondary amine compounds |
| EP3492473B1 (en) * | 2012-08-21 | 2025-07-30 | Janssen Pharmaceutica NV | Haptens of olanzapine |
-
2013
- 2013-08-20 EP EP18202081.8A patent/EP3492473B1/en active Active
- 2013-08-20 WO PCT/US2013/055700 patent/WO2014031587A1/en not_active Ceased
- 2013-08-20 AU AU2013306018A patent/AU2013306018B2/en active Active
- 2013-08-20 PT PT13753774T patent/PT2888269T/pt unknown
- 2013-08-20 ES ES18202081T patent/ES3043017T3/es active Active
- 2013-08-20 CN CN201380054963.3A patent/CN104854110B/zh active Active
- 2013-08-20 CA CA2882454A patent/CA2882454C/en active Active
- 2013-08-20 ES ES13753774T patent/ES2701062T3/es active Active
- 2013-08-20 PL PL13753774T patent/PL2888269T3/pl unknown
- 2013-08-20 JP JP2015528568A patent/JP6171014B2/ja active Active
- 2013-08-20 EP EP13753774.2A patent/EP2888269B1/en active Active
- 2013-08-20 TR TR2018/16378T patent/TR201816378T4/tr unknown
- 2013-08-20 US US13/970,653 patent/US9303041B2/en active Active
-
2017
- 2017-07-03 JP JP2017130471A patent/JP6423490B2/ja active Active
-
2018
- 2018-10-18 JP JP2018196525A patent/JP6763000B2/ja active Active
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