JP2016518140A - Ｉ型インターフェロンの環状ジヌクレオチド誘導法 - Google Patents

Ｉ型インターフェロンの環状ジヌクレオチド誘導法 Download PDF

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JP2016518140A
JP2016518140A JP2016512084A JP2016512084A JP2016518140A JP 2016518140 A JP2016518140 A JP 2016518140A JP 2016512084 A JP2016512084 A JP 2016512084A JP 2016512084 A JP2016512084 A JP 2016512084A JP 2016518140 A JP2016518140 A JP 2016518140A
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cyclic dinucleotide
cyclic
cells
sting
cell
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Japanese (ja)
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ラッセル イー． ヴァンス
ラッセル イー． ヴァンス
ミング シー． ハモンド
ミング シー． ハモンド
ダーラ バーデット
ダーラ バーデット
エリー ジェイ． ダイナー
エリー ジェイ． ダイナー
スティーブン シー． ウィルソン
スティーブン シー． ウィルソン
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University of California
University of California, Los Angeles
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University of California, San Diego
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2016512084A 2013-05-03 2014-05-02 Ｉ型インターフェロンの環状ジヌクレオチド誘導法 Pending JP2016518140A (ja)

Applications Claiming Priority (3)

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US201361819499P 2013-05-03 2013-05-03
US61/819,499 2013-05-03
PCT/US2014/036685 WO2014179760A1 (en) 2013-05-03 2014-05-02 Cyclic di-nucleotide induction of type i interferon

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JP2018237955A Pending JP2019068829A (ja) 2013-05-03 2018-12-20 Ｉ型インターフェロンの環状ジヌクレオチド誘導法
JP2021025792A Withdrawn JP2021074025A (ja) 2013-05-03 2021-02-22 Ｉ型インターフェロンの環状ジヌクレオチド誘導法

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US (3) US20140329889A1 (enExample)
EP (1) EP2992000B1 (enExample)
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CN (1) CN105377867B (enExample)
ES (1) ES2822584T3 (enExample)
WO (1) WO2014179760A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021520389A (ja) * 2018-04-06 2021-08-19 インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール，ヴイ．ヴイ．アイ． ２’３’−環状ジヌクレオチド
JP2024514707A (ja) * 2021-04-20 2024-04-02 アンスティテュ・クリー 免疫療法における使用のための組成物及び方法

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