|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
|
CA2853829C
(en)
|
2011-07-22 |
2023-09-26 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
US10704021B2
(en)
|
2012-03-15 |
2020-07-07 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US9458450B2
(en)
|
2012-03-15 |
2016-10-04 |
Flodesign Sonics, Inc. |
Acoustophoretic separation technology using multi-dimensional standing waves
|
|
US9950282B2
(en)
|
2012-03-15 |
2018-04-24 |
Flodesign Sonics, Inc. |
Electronic configuration and control for acoustic standing wave generation
|
|
US10967298B2
(en)
|
2012-03-15 |
2021-04-06 |
Flodesign Sonics, Inc. |
Driver and control for variable impedence load
|
|
US9834786B2
(en)
|
2012-04-25 |
2017-12-05 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated targeting with large targeting vectors
|
|
WO2014165825A2
(en)
|
2013-04-04 |
2014-10-09 |
President And Fellows Of Harvard College |
Therapeutic uses of genome editing with crispr/cas systems
|
|
LT2986729T
(lt)
|
2013-04-16 |
2018-10-25 |
Regeneron Pharmaceuticals, Inc. |
Žiurkės genomo tikslinė modifikacija
|
|
EP3019595A4
(en)
|
2013-07-09 |
2016-11-30 |
|
THERAPEUTIC USES OF A GENERIC CHANGE WITH CRISPR / CAS SYSTEMS
|
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
GB201315321D0
(en)
*
|
2013-08-28 |
2013-10-09 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Transduction Buffer
|
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
EP3066201B1
(en)
|
2013-11-07 |
2018-03-07 |
Editas Medicine, Inc. |
Crispr-related methods and compositions with governing grnas
|
|
CN110951779B
(zh)
|
2013-12-11 |
2024-04-16 |
瑞泽恩制药公司 |
用于靶向修饰基因组的方法和组合物
|
|
US9840699B2
(en)
|
2013-12-12 |
2017-12-12 |
President And Fellows Of Harvard College |
Methods for nucleic acid editing
|
|
WO2015105955A1
(en)
|
2014-01-08 |
2015-07-16 |
Flodesign Sonics, Inc. |
Acoustophoresis device with dual acoustophoretic chamber
|
|
KR102827558B1
(ko)
*
|
2014-04-18 |
2025-07-11 |
에디타스 메디신, 인코포레이티드 |
암 면역요법을 위한 crispr-cas-관련 방법, 조성물 및 구성성분
|
|
SG11201609634YA
(en)
|
2014-06-06 |
2016-12-29 |
Regeneron Pharma |
Methods and compositions for modifying a targeted locus
|
|
PL3161128T3
(pl)
|
2014-06-26 |
2019-02-28 |
Regeneron Pharmaceuticals, Inc. |
Sposoby i kompozycje do celowanych modyfikacji genetycznych i sposoby zastosowania
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
US9970030B2
(en)
|
2014-08-27 |
2018-05-15 |
Caribou Biosciences, Inc. |
Methods for increasing CAS9-mediated engineering efficiency
|
|
BR112017008693A2
(pt)
*
|
2014-10-31 |
2018-02-27 |
The Trustees Of The University Of Pennsylvania |
célula t modificada, métodos para gerar uma célula t modificada, para tratar uma doença ou condição, para estimular uma resposta imune mediada por célula t e para terapia de transferência de célula adotiva, uso de uma célula t modificada, e, composição.
|
|
US12180263B2
(en)
|
2014-11-06 |
2024-12-31 |
President And Fellows Of Harvard College |
Cells lacking B2M surface expression and methods for allogeneic administration of such cells
|
|
CA3176380A1
(en)
|
2014-11-21 |
2016-05-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modification using paired guide rnas
|
|
EP3653048B9
(en)
|
2014-12-19 |
2023-10-04 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modification through single-step multiple targeting
|
|
MX2017012407A
(es)
*
|
2015-03-27 |
2018-03-07 |
Harvard College |
Celulas t modificadas y métodos para hacer y usar las mismas.
|
|
EP4335918A3
(en)
*
|
2015-04-03 |
2024-04-17 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
|
US11708572B2
(en)
|
2015-04-29 |
2023-07-25 |
Flodesign Sonics, Inc. |
Acoustic cell separation techniques and processes
|
|
US11021699B2
(en)
|
2015-04-29 |
2021-06-01 |
FioDesign Sonics, Inc. |
Separation using angled acoustic waves
|
|
US11377651B2
(en)
|
2016-10-19 |
2022-07-05 |
Flodesign Sonics, Inc. |
Cell therapy processes utilizing acoustophoresis
|
|
CN107921148A
(zh)
|
2015-05-08 |
2018-04-17 |
哈佛学院校长同事会 |
通用供体干细胞和相关方法
|
|
KR102461443B1
(ko)
|
2015-07-13 |
2022-10-31 |
피벗 바이오, 인크. |
식물 형질 개선을 위한 방법 및 조성물
|
|
EP4273782A3
(en)
*
|
2015-07-25 |
2023-12-27 |
Frost, Habib |
A system, device and a method for providing a therapy or a cure for cancer and other pathological states
|
|
US11474085B2
(en)
|
2015-07-28 |
2022-10-18 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
US11459540B2
(en)
|
2015-07-28 |
2022-10-04 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
CA2993431A1
(en)
|
2015-07-31 |
2017-02-09 |
Regents Of The University Of Minnesota |
Nuclease based knockouts of immunological checkpoint genes in immune cells
|
|
CN108601821B
(zh)
*
|
2015-10-05 |
2023-09-19 |
精密生物科学公司 |
包含经修饰的人T细胞受体α恒定区基因的经遗传修饰的细胞
|
|
ES2883116T3
(es)
|
2015-10-05 |
2021-12-07 |
Prec Biosciences Inc |
Meganucleasas diseñadas con secuencias de reconocimiento encontradas en el gen de la región constante alfa del receptor de células T humanas
|
|
US11479516B2
(en)
|
2015-10-05 |
2022-10-25 |
Massachusetts Institute Of Technology |
Nitrogen fixation using refactored NIF clusters
|
|
MY194628A
(en)
|
2015-10-23 |
2022-12-07 |
Eureka Therapeutics Inc |
Antibody/t-cell receptor chimeric constructs and uses thereof
|
|
IL294014B2
(en)
|
2015-10-23 |
2024-07-01 |
Harvard College |
Nucleobase editors and uses thereof
|
|
GB201521101D0
(en)
|
2015-11-30 |
2016-01-13 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Transduction buffer
|
|
JP7128741B2
(ja)
|
2015-12-18 |
2022-08-31 |
サンガモ セラピューティクス， インコーポレイテッド |
Ｔ細胞受容体の標的化破壊
|
|
WO2017106537A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the mhc cell receptor
|
|
GB201604458D0
(en)
|
2016-03-16 |
2016-04-27 |
Immatics Biotechnologies Gmbh |
Peptides and combination of peptides for use in immunotherapy against cancers
|
|
AU2017250769B2
(en)
|
2016-04-15 |
2022-07-14 |
Memorial Sloan Kettering Cancer Center |
Transgenic T cell and chimeric antigen receptor T cell compositions and related methods
|
|
US11214789B2
(en)
|
2016-05-03 |
2022-01-04 |
Flodesign Sonics, Inc. |
Concentration and washing of particles with acoustics
|
|
US11085035B2
(en)
|
2016-05-03 |
2021-08-10 |
Flodesign Sonics, Inc. |
Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
|
|
AU2017306676B2
(en)
|
2016-08-03 |
2024-02-22 |
President And Fellows Of Harvard College |
Adenosine nucleobase editors and uses thereof
|
|
EP3497214B1
(en)
|
2016-08-09 |
2023-06-28 |
President and Fellows of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
ES2901989T3
(es)
|
2016-08-24 |
2022-03-24 |
Sangamo Therapeutics Inc |
Nucleasas específicas de objetivo modificadas
|
|
US11542509B2
(en)
|
2016-08-24 |
2023-01-03 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
GB201616238D0
(en)
*
|
2016-09-23 |
2016-11-09 |
Adaptimmune Ltd |
Modified T cells
|
|
KR20250011252A
(ko)
*
|
2016-09-30 |
2025-01-21 |
포세이다 테라퓨틱스, 인크. |
변형된 줄기세포 기억 t 세포, 이의 제조 방법 및 사용 방법
|
|
US20190119636A1
(en)
|
2017-10-23 |
2019-04-25 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
MA46354A
(fr)
|
2016-10-03 |
2019-08-07 |
Juno Therapeutics Inc |
Molécules se liant spécifiquement au vph
|
|
WO2018071868A1
(en)
|
2016-10-14 |
2018-04-19 |
President And Fellows Of Harvard College |
Aav delivery of nucleobase editors
|
|
EP3529347A1
(en)
|
2016-10-19 |
2019-08-28 |
Flodesign Sonics, Inc. |
Affinity cell extraction by acoustics
|
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
|
WO2018081476A2
(en)
*
|
2016-10-27 |
2018-05-03 |
Intima Bioscience, Inc. |
Viral methods of t cell therapy
|
|
CN110023497B
(zh)
|
2016-11-07 |
2021-07-13 |
杰诺维有限公司 |
用于t细胞受体合成和向tcr呈递细胞进行稳定的基因组整合的两部分装置
|
|
AU2017352590B2
(en)
*
|
2016-11-07 |
2023-10-19 |
Genovie Ab |
An engineered multi-component system for identification and characterisation of T-cell receptors, T-cell antigens and their functional interaction
|
|
CA3039422A1
(en)
*
|
2016-11-07 |
2018-05-11 |
Genovie Ab |
An engineered two-part cellular device for discovery and characterisation of t-cell receptor interaction with cognate antigen
|
|
EP3535387B1
(en)
|
2016-11-07 |
2022-01-12 |
Genovie AB |
An engineered multi-component system for identification and characterisation of t-cell receptors and t-cell antigens
|
|
KR102379955B1
(ko)
|
2016-12-08 |
2022-03-29 |
이매틱스 바이오테크놀로지스 게엠베하 |
짝짓기가 향상된 t 세포 수용체
|
|
DE102016123893A1
(de)
|
2016-12-08 |
2018-06-14 |
Immatics Biotechnologies Gmbh |
T-Zellrezeptoren mit verbesserter Bindung
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
CA3049258A1
(en)
|
2017-01-12 |
2018-07-19 |
Pivot Bio, Inc. |
Methods and compositions for improving plant traits
|
|
EP3592853A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Suppression of pain by gene editing
|
|
WO2018165631A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Cancer vaccine
|
|
WO2018165629A1
(en)
|
2017-03-10 |
2018-09-13 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
KR20240116572A
(ko)
|
2017-03-23 |
2024-07-29 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제
|
|
AU2018258045B2
(en)
|
2017-04-26 |
2024-02-29 |
Eureka Therapeutics, Inc. |
Chimeric antibody/T-cell receptor constructs and uses thereof
|
|
CN110914289B
(zh)
|
2017-05-12 |
2024-05-14 |
克里斯珀医疗股份公司 |
用于工程化细胞的材料和方法及其在免疫肿瘤学中的用途
|
|
US11560566B2
(en)
|
2017-05-12 |
2023-01-24 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
CA3067382A1
(en)
|
2017-06-15 |
2018-12-20 |
The Regents Of The University Of California |
Targeted non-viral dna insertions
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
AU2018292181B2
(en)
|
2017-06-30 |
2025-04-10 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
EP3645038A1
(en)
|
2017-06-30 |
2020-05-06 |
Precision Biosciences, Inc. |
Genetically-modified t cells comprising a modified intron in the t cell receptor alpha gene
|
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
|
BR112020002438A2
(pt)
|
2017-08-08 |
2020-07-28 |
Sangamo Therapeutics, Inc. |
direcionamento celular mediado por receptores de antígenos quiméricos
|
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
|
WO2019067805A1
(en)
*
|
2017-09-27 |
2019-04-04 |
University Of Southern California |
NEW PLATFORMS FOR CO-STIMULATION, NEW CAR DESIGNS AND OTHER IMPROVEMENTS FOR ADOPTIVE CELL THERAPY
|
|
US11952408B2
(en)
|
2017-10-03 |
2024-04-09 |
Juno Therapeutics, Inc. |
HPV-specific binding molecules
|
|
JP7333495B2
(ja)
*
|
2017-10-10 |
2023-08-25 |
国立大学法人広島大学 |
エフェクターＴ細胞（Ｔｅｆｆ）抗原受容体を用いた抗原特異的制御性Ｔ細胞（Ｔｒｅｇ）の作出技術
|
|
EP3702453A4
(en)
*
|
2017-10-10 |
2021-07-21 |
Hiroshima University |
TOTAL REPLACEMENT TECHNIQUE FOR T-LYMPHOCYTE RECEPTOR USING PLATINUM TALENE
|
|
WO2019079347A1
(en)
|
2017-10-16 |
2019-04-25 |
The Broad Institute, Inc. |
USES OF BASIC EDITORS ADENOSINE
|
|
US11993778B2
(en)
|
2017-10-25 |
2024-05-28 |
Pivot Bio, Inc. |
Methods and compositions for improving engineered microbes that fix nitrogen
|
|
CN117757706A
(zh)
|
2017-10-25 |
2024-03-26 |
皮沃特生物股份有限公司 |
靶向改良植物性状的固氮的基因靶标
|
|
IL305485B2
(en)
|
2017-10-27 |
2025-10-01 |
Univ California |
Targeted replacement of endogenous T cell receptors
|
|
BR112020008704A2
(pt)
*
|
2017-10-30 |
2020-11-10 |
Pact Pharma, Inc. |
edição de genes de células primárias
|
|
IL274323B2
(en)
*
|
2017-11-09 |
2024-10-01 |
Sangamo Therapeutics Inc |
Genetic modification of cytokine inducible sh2-containing protein (cish) gene
|
|
WO2019118508A1
(en)
*
|
2017-12-12 |
2019-06-20 |
The Trustees Of The University Of Pennsylvania |
Genetically modified immune cells targeting ny-eso-1 and methods of use thereof
|
|
KR20220066413A
(ko)
|
2017-12-14 |
2022-05-24 |
프로디자인 소닉스, 인크. |
음향 트랜스듀서 구동기 및 제어기
|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
JP2021510304A
(ja)
*
|
2018-01-10 |
2021-04-22 |
エージーシー バイオロジクス， インコーポレイテッド |
双方向ｃｈｅｆ１ベクター
|
|
KR102828999B1
(ko)
*
|
2018-02-11 |
2025-07-04 |
메모리얼 슬로안 케터링 캔서 센터 |
비-hla 제한된 t 세포 수용체 및 이의 용도
|
|
CN112041432A
(zh)
|
2018-02-15 |
2020-12-04 |
纪念斯隆-凯特林癌症中心 |
Foxp3靶向剂组合物以及用于过继细胞疗法的使用方法
|
|
WO2019195310A1
(en)
|
2018-04-02 |
2019-10-10 |
Pact Pharma, Inc. |
Peptide-mhc compacts
|
|
MX2020010459A
(es)
*
|
2018-04-05 |
2021-01-20 |
Juno Therapeutics Inc |
Metodos para producir celulas que expresan un receptor recombinante y composiciones relacionadas.
|
|
TWI840351B
(zh)
|
2018-04-05 |
2024-05-01 |
美商奇諾治療有限公司 |
T細胞受體及表現其之工程化細胞
|
|
KR20210020873A
(ko)
*
|
2018-04-05 |
2021-02-24 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 τ 세포, 관련 폴리뉴클레오티드 및 방법
|
|
AU2019252527B2
(en)
|
2018-04-12 |
2024-02-22 |
Precision Biosciences, Inc. |
Optimized engineered nucleases having specificity for the human T cell receptor alpha constant region gene
|
|
US20200208177A1
(en)
*
|
2018-04-18 |
2020-07-02 |
Ligandal, Inc. |
Methods and compositions for genome editing
|
|
IL278348B2
(en)
|
2018-05-11 |
2025-03-01 |
Crispr Therapeutics Ag |
Methods and preparations for treating cancer
|
|
EP3797160A1
(en)
|
2018-05-23 |
2021-03-31 |
The Broad Institute Inc. |
Base editors and uses thereof
|
|
EP3806888B1
(en)
|
2018-06-12 |
2024-01-31 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
EP3814302A4
(en)
|
2018-06-27 |
2022-06-29 |
Pivot Bio, Inc. |
Agricultural compositions comprising remodeled nitrogen fixing microbes
|
|
WO2020014261A1
(en)
|
2018-07-09 |
2020-01-16 |
The Broad Institute, Inc. |
Rna programmable epigenetic rna modifiers and uses thereof
|
|
BR112021000268A2
(pt)
|
2018-07-11 |
2021-05-11 |
Pivot Bio, Inc. |
liberação dinâmica de nitrogênio temporalmente e espacialmente direcionada por micróbios remodelados
|
|
EP3868887A4
(en)
*
|
2018-09-25 |
2022-12-07 |
Microbial Chemistry Research Foundation |
NOVEL VIRAL VECTOR AND METHODS OF PRODUCTION AND USE THEREOF
|
|
SG11202103571XA
(en)
*
|
2018-10-16 |
2021-05-28 |
Intellia Therapeutics Inc |
Compositions and methods for immunotherapy
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
GB201817821D0
(en)
*
|
2018-10-31 |
2018-12-19 |
Ospedale San Raffaele Srl |
TCR and peptides
|
|
EP3877525A2
(en)
|
2018-12-18 |
2021-09-15 |
Braskem S.A. |
Co-production pathway for 3-hp and acetyl-coa derivatives from malonate semialdehyde
|
|
CN113825393A
(zh)
|
2018-12-21 |
2021-12-21 |
皮沃特生物股份有限公司 |
改善植物性状的方法、组合物和培养基
|
|
EP3880807A2
(en)
|
2018-12-28 |
2021-09-22 |
Braskem S.A. |
Modulation of carbon flux through the meg and c3 pathways for the improved production of monoethylene glycol and c3 compounds
|
|
CA3123940A1
(en)
|
2019-01-07 |
2020-07-16 |
Pivot Bio, Inc. |
Plant colonization assays using natural microbial barcodes
|
|
WO2020154500A1
(en)
|
2019-01-23 |
2020-07-30 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
CA3129316A1
(en)
|
2019-02-12 |
2020-08-20 |
Pact Pharma, Inc. |
Compositions and methods for identification of antigen specific t cells
|
|
KR20210136044A
(ko)
|
2019-03-01 |
2021-11-16 |
브라스켐 에세.아. |
4-하이드록시메틸푸르푸랄 및 그 유도체의 생체 내 합성 방법
|
|
WO2020190363A1
(en)
|
2019-03-19 |
2020-09-24 |
Massachusetts Institute Of Technology |
Control of nitrogen fixation in rhizobia that associate with cereals
|
|
BR112021018607A2
(pt)
|
2019-03-19 |
2021-11-23 |
Massachusetts Inst Technology |
Métodos e composições para editar sequências de nucleotídeos
|
|
KR102691932B1
(ko)
|
2019-04-03 |
2024-08-06 |
프리시젼 바이오사이언시스 인코포레이티드 |
마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포
|
|
BR112021018925A2
(pt)
|
2019-04-04 |
2022-01-18 |
Braskem Sa |
Modificação metabólica para consumo simultâneo de xilose e glicose para produção de produtos químicos a partir de açúcares de segunda geração
|
|
EP3956349A1
(en)
|
2019-04-17 |
2022-02-23 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
JP2022529531A
(ja)
|
2019-04-24 |
2022-06-22 |
ピボット バイオ， インコーポレイテッド |
植物形質を改善するために窒素固定を標的とする遺伝子標的
|
|
MX2021013359A
(es)
|
2019-04-30 |
2022-01-31 |
Crispr Therapeutics Ag |
Terapia de celulas alogénicas de neoplasias malignas de células b usando células t modificadas genéticamente dirigidas a cd19.
|
|
WO2020237045A1
(en)
|
2019-05-21 |
2020-11-26 |
Sangamo Therapeutics, Inc. |
Controlled transgene expression in regulatory t cells
|
|
WO2021016608A1
(en)
|
2019-07-25 |
2021-01-28 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
CA3148179A1
(en)
|
2019-08-20 |
2021-02-25 |
Bruce J. Mccreedy Jr. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
|
CN110484523A
(zh)
*
|
2019-09-06 |
2019-11-22 |
上海斯丹赛生物技术有限公司 |
一种锌指核酸酶及其应用
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
WO2021076744A1
(en)
*
|
2019-10-15 |
2021-04-22 |
The Regents Of The University Of California |
Gene targets for manipulating t cell behavior
|
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
WO2021221690A1
(en)
|
2020-05-01 |
2021-11-04 |
Pivot Bio, Inc. |
Modified bacterial strains for improved fixation of nitrogen
|
|
US12281980B2
(en)
|
2020-05-01 |
2025-04-22 |
Pivot Bio, Inc. |
Measurement of nitrogen fixation and incorporation
|
|
CA3172322A1
(en)
|
2020-05-01 |
2021-11-04 |
Karsten TEMME |
Modified bacterial strains for improved fixation of nitrogen
|
|
EP4142477A1
(en)
|
2020-05-01 |
2023-03-08 |
Pivot Bio, Inc. |
Stable liquid formulations for nitrogen-fixing microorganisms
|
|
AU2021267940A1
(en)
|
2020-05-08 |
2022-12-08 |
President And Fellows Of Harvard College |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
|
EP4149245A2
(en)
|
2020-05-13 |
2023-03-22 |
Pivot Bio, Inc. |
De-repression of nitrogen fixation in gram-positive microorganisms
|
|
KR20230042283A
(ko)
|
2020-06-26 |
2023-03-28 |
주노 테라퓨틱스 게엠베하 |
재조합 수용체를 조건부로 발현하는 조작된 ｔ 세포, 관련된 폴리뉴클레오티드 및 방법
|
|
WO2022035793A1
(en)
|
2020-08-10 |
2022-02-17 |
Precision Biosciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
EP4284823A1
(en)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
CN117693508A
(zh)
|
2021-03-03 |
2024-03-12 |
朱诺治疗学股份有限公司 |
T细胞疗法和dgk抑制剂的组合
|
|
WO2023278804A1
(en)
|
2021-07-02 |
2023-01-05 |
Pivot Bio, Inc. |
Genetically-engineered bacterial strains for improved fixation of nitrogen
|
|
AU2022366987A1
(en)
|
2021-10-14 |
2024-05-16 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
|
JP2024539291A
(ja)
*
|
2021-10-25 |
2024-10-28 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
神経膠芽腫を治療するための方法および組成物
|
|
WO2023081767A1
(en)
|
2021-11-05 |
2023-05-11 |
Precision Biosciences, Inc. |
Methods for immunotherapy
|
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
|
WO2023122805A1
(en)
|
2021-12-20 |
2023-06-29 |
Vestaron Corporation |
Sorbitol driven selection pressure method
|
|
WO2023201133A1
(en)
|
2022-04-14 |
2023-10-19 |
Board Of Regents Of The University Of Nebraska |
Cell therapy for alzheimer's disease
|
|
CN120152717A
(zh)
|
2022-09-08 |
2025-06-13 |
朱诺治疗学股份有限公司 |
T细胞疗法和连续或间歇dgk抑制剂给药的组合
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
WO2024137259A1
(en)
|
2022-12-23 |
2024-06-27 |
Pivot Bio, Inc. |
Combination of various nitrogen fixing bacteria with various biological products to achieve synergistic effects
|
|
EP4646223A1
(en)
|
2023-01-05 |
2025-11-12 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for the human t cell receptor alpha constant region gene
|
|
AU2024214593A1
(en)
|
2023-02-03 |
2025-08-07 |
C3S2 Gmbh |
Methods for non-viral manufacturing of engineered immune cells
|
|
WO2025155521A1
(en)
|
2024-01-18 |
2025-07-24 |
Pivot Bio, Inc. |
Host cells for enhanced plant growth
|
|
WO2025155518A1
(en)
|
2024-01-18 |
2025-07-24 |
Pivot Bio, Inc. |
Host cells for enhanced plant growth
|