|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
|
WO2013066438A2
(en)
|
2011-07-22 |
2013-05-10 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
US10967298B2
(en)
|
2012-03-15 |
2021-04-06 |
Flodesign Sonics, Inc. |
Driver and control for variable impedence load
|
|
US10704021B2
(en)
|
2012-03-15 |
2020-07-07 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
US9458450B2
(en)
|
2012-03-15 |
2016-10-04 |
Flodesign Sonics, Inc. |
Acoustophoretic separation technology using multi-dimensional standing waves
|
|
US9950282B2
(en)
|
2012-03-15 |
2018-04-24 |
Flodesign Sonics, Inc. |
Electronic configuration and control for acoustic standing wave generation
|
|
RU2645475C2
(ru)
|
2012-04-25 |
2018-02-21 |
Регенерон Фармасьютикалз, Инк. |
Опосредованное нуклеазой нацеливание с большими нацеливающими векторами
|
|
JP2016522679A
(ja)
|
2013-04-04 |
2016-08-04 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ＣＲＩＳＰＲ／Ｃａｓ系を用いたゲノム編集の治療的使用
|
|
DK2986729T3
(en)
|
2013-04-16 |
2018-10-29 |
Regeneron Pharma |
TARGETED MODIFICATION OF ROOT THROUGH
|
|
JP2016528890A
(ja)
|
2013-07-09 |
2016-09-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ＣＲＩＳＰＲ／Ｃａｓ系を用いるゲノム編集の治療用の使用
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
GB201315321D0
(en)
*
|
2013-08-28 |
2013-10-09 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Transduction Buffer
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
US9388430B2
(en)
|
2013-09-06 |
2016-07-12 |
President And Fellows Of Harvard College |
Cas9-recombinase fusion proteins and uses thereof
|
|
US9340799B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
MRNA-sensing switchable gRNAs
|
|
CN106459995B
(zh)
|
2013-11-07 |
2020-02-21 |
爱迪塔斯医药有限公司 |
使用统治型gRNA的CRISPR相关方法和组合物
|
|
WO2015088643A1
(en)
|
2013-12-11 |
2015-06-18 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a genome
|
|
US20150166984A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting alpha-antitrypsin point mutations
|
|
CA2935960C
(en)
|
2014-01-08 |
2023-01-10 |
Bart Lipkens |
Acoustophoresis device with dual acoustophoretic chamber
|
|
KR102595473B1
(ko)
*
|
2014-04-18 |
2023-10-30 |
에디타스 메디신, 인코포레이티드 |
암 면역요법을 위한 crispr-cas-관련 방법, 조성물 및 구성성분
|
|
RU2704283C9
(ru)
*
|
2014-06-06 |
2020-02-07 |
Регенерон Фармасьютикалз, Инк. |
Способы и композиции для модификации целевого локуса
|
|
PT3161128T
(pt)
|
2014-06-26 |
2018-11-21 |
Regeneron Pharma |
Métodos e composições para modificações genéticas alvejadas e métodos de utilização
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
CA2959070C
(en)
|
2014-08-27 |
2020-11-10 |
Caribou Biosciences, Inc. |
Methods for increasing cas9-mediated engineering efficiency
|
|
KR20170075013A
(ko)
|
2014-10-31 |
2017-06-30 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
Cart 세포에서 유전자 발현의 변경 및 그의 용도
|
|
EP3215623A4
(en)
|
2014-11-06 |
2018-09-26 |
President and Fellows of Harvard College |
Cells lacking b2m surface expression and methods for allogeneic administration of such cells
|
|
CA2968440A1
(en)
|
2014-11-21 |
2016-05-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modification using paired guide rnas
|
|
BR112017013104A2
(en)
|
2014-12-19 |
2018-05-15 |
Regeneron Pharmaceuticals, Inc. |
methods for modifying a target genomic locus in a cell, for enhancing homologous recombination at a target genomic locus in a cell, and for producing an f0 generation from a nonhuman animal.
|
|
AU2016243583B2
(en)
*
|
2015-03-27 |
2022-03-10 |
President And Fellows Of Harvard College |
Modified T cells and methods of making and using the same
|
|
WO2016161446A1
(en)
*
|
2015-04-03 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
|
US11377651B2
(en)
|
2016-10-19 |
2022-07-05 |
Flodesign Sonics, Inc. |
Cell therapy processes utilizing acoustophoresis
|
|
US11021699B2
(en)
|
2015-04-29 |
2021-06-01 |
FioDesign Sonics, Inc. |
Separation using angled acoustic waves
|
|
US11708572B2
(en)
|
2015-04-29 |
2023-07-25 |
Flodesign Sonics, Inc. |
Acoustic cell separation techniques and processes
|
|
CA2988854A1
(en)
|
2015-05-08 |
2016-11-17 |
President And Fellows Of Harvard College |
Universal donor stem cells and related methods
|
|
KR102197507B1
(ko)
|
2015-07-13 |
2020-12-31 |
피벗 바이오, 인크. |
식물 형질 개선을 위한 방법 및 조성물
|
|
JP7602862B2
(ja)
*
|
2015-07-25 |
2024-12-19 |
ハビブ・フロスト |
がんおよび他の病的状態における治療または治癒を提供する、システム、デバイスおよび方法
|
|
US11474085B2
(en)
|
2015-07-28 |
2022-10-18 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
US11459540B2
(en)
|
2015-07-28 |
2022-10-04 |
Flodesign Sonics, Inc. |
Expanded bed affinity selection
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
EP4108255A1
(en)
|
2015-10-05 |
2022-12-28 |
Precision Biosciences, Inc. |
Genetically-modified cells comprising a modified human t cell receptor alpha constant region gene
|
|
WO2017062412A1
(en)
|
2015-10-05 |
2017-04-13 |
Massachusetts Institute Of Technology |
Nitrogen fixation using refactored nif clusters
|
|
ES2883116T3
(es)
|
2015-10-05 |
2021-12-07 |
Prec Biosciences Inc |
Meganucleasas diseñadas con secuencias de reconocimiento encontradas en el gen de la región constante alfa del receptor de células T humanas
|
|
SG10202104041PA
(en)
|
2015-10-23 |
2021-06-29 |
Harvard College |
Nucleobase editors and uses thereof
|
|
CN116059316A
(zh)
*
|
2015-10-23 |
2023-05-05 |
优瑞科生物技术公司 |
抗体/t细胞受体嵌合构建体及其用途
|
|
GB201521101D0
(en)
|
2015-11-30 |
2016-01-13 |
Koninklijke Nederlandse Akademie Van Wetenschappen |
Transduction buffer
|
|
AU2016374253B2
(en)
|
2015-12-18 |
2021-10-21 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the MHC cell receptor
|
|
ES2983043T3
(es)
|
2015-12-18 |
2024-10-21 |
Sangamo Therapeutics Inc |
Alteración dirigida del receptor de células T
|
|
GB201604458D0
(en)
|
2016-03-16 |
2016-04-27 |
Immatics Biotechnologies Gmbh |
Peptides and combination of peptides for use in immunotherapy against cancers
|
|
ES3039670T3
(en)
|
2016-04-15 |
2025-10-23 |
Memorial Sloan Kettering Cancer Center |
Transgenic t cell and chimeric antigen receptor t cell compositions and related methods
|
|
US11085035B2
(en)
|
2016-05-03 |
2021-08-10 |
Flodesign Sonics, Inc. |
Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
|
|
US11214789B2
(en)
|
2016-05-03 |
2022-01-04 |
Flodesign Sonics, Inc. |
Concentration and washing of particles with acoustics
|
|
KR20250103795A
(ko)
|
2016-08-03 |
2025-07-07 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
|
IL300783B2
(en)
|
2016-08-24 |
2026-03-01 |
Sangamo Therapeutics Inc |
Engineered nucleases with target-specific zinc fingers
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
GB201616238D0
(en)
*
|
2016-09-23 |
2016-11-09 |
Adaptimmune Ltd |
Modified T cells
|
|
CA3105873A1
(en)
*
|
2016-09-30 |
2018-04-05 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
US20190119636A1
(en)
|
2017-10-23 |
2019-04-25 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
EP3519433A1
(en)
|
2016-10-03 |
2019-08-07 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
|
SG11201903089RA
(en)
|
2016-10-14 |
2019-05-30 |
Harvard College |
Aav delivery of nucleobase editors
|
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
|
CN110494543A
(zh)
|
2016-10-19 |
2019-11-22 |
弗洛设计声能学公司 |
通过声学的亲和细胞提取
|
|
CN111344396A
(zh)
*
|
2016-10-27 |
2020-06-26 |
因提玛生物科学公司 |
制备遗传修饰细胞的病毒方法
|
|
CA3039420A1
(en)
|
2016-11-07 |
2018-05-11 |
Genovie Ab |
A two-part device for t-cell receptor synthesis and stable genomic integration to tcr-presenting cells
|
|
JP6858266B2
(ja)
*
|
2016-11-07 |
2021-04-14 |
ジェノヴィー エービーＧｅｎｏｖｉｅ Ａｂ |
Ｔ細胞レセプター、ｔ細胞抗原及びそれらの機能的相互作用の同定及び特徴決定のための遺伝子操作された多成分システム
|
|
CA3038917A1
(en)
|
2016-11-07 |
2018-05-11 |
Genovie Ab |
An engineered multi-component system for identification and characterisation of t-cell receptors and t-cell antigens
|
|
JP7582779B2
(ja)
*
|
2016-11-07 |
2024-11-13 |
ジェノヴィー エービー |
Ｔ細胞レセプターの同族抗原との相互作用の発見及び特徴決定のための遺伝子操作された二部構成細胞デバイス
|
|
EP4317432A3
(en)
|
2016-12-08 |
2024-04-17 |
Immatics Biotechnologies GmbH |
T cell receptors with improved pairing
|
|
DE102016123893A1
(de)
|
2016-12-08 |
2018-06-14 |
Immatics Biotechnologies Gmbh |
T-Zellrezeptoren mit verbesserter Bindung
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
UA129256C2
(uk)
|
2017-01-12 |
2025-03-05 |
Півот Байо, Інк. |
Спосіб ідентифікації штаму мікроорганізму, який продукує азот, небобова рослина, колонізована таким штамом, спосіб збільшення фіксації азоту у небобових рослин та композиція для збільшення фіксації азоту у небобових рослин
|
|
EP3592381A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Cancer vaccine
|
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
WO2018165629A1
(en)
|
2017-03-10 |
2018-09-13 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
WO2018176009A1
(en)
|
2017-03-23 |
2018-09-27 |
President And Fellows Of Harvard College |
Nucleobase editors comprising nucleic acid programmable dna binding proteins
|
|
AU2018258045B2
(en)
|
2017-04-26 |
2024-02-29 |
Eureka Therapeutics, Inc. |
Chimeric antibody/T-cell receptor constructs and uses thereof
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
BR112019023608A2
(pt)
|
2017-05-12 |
2020-05-26 |
Crispr Therapeutics Ag |
Materiais e métodos para células manipuladas e seus usos em imuno-oncologia
|
|
SG11201912179SA
(en)
|
2017-06-15 |
2020-01-30 |
Univ California |
Targeted non-viral dna insertions
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
CA3067914A1
(en)
|
2017-06-30 |
2019-01-03 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
JP2020529834A
(ja)
|
2017-06-30 |
2020-10-15 |
プレシジョン バイオサイエンシズ，インク． |
Ｔ細胞受容体アルファ遺伝子の改変されたイントロンを含む遺伝子改変ｔ細胞
|
|
CA3068634A1
(en)
|
2017-06-30 |
2019-01-03 |
Memorial Sloan Kettering Cancer Center |
Compositions and methods for adoptive cell therapy for cancer
|
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
|
CA3071683A1
(en)
|
2017-08-08 |
2019-02-14 |
Sangamo Therapeutics, Inc. |
Chimeric antigen receptor mediated cell targeting
|
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
BR112020005938A2
(pt)
*
|
2017-09-27 |
2020-11-17 |
University Of Southern California |
célula imune ou população de células imunes da mesma, célula efetora imune ou célula-tronco, célula que apresenta antígeno, polinucleotídeo recombinante, vetor, composição que compreende uma célula imune efetora ou uma célula-tronco, métodos para produzir uma célula efetora imune que expressa receptor imune de ocorrência não natural, para gerar uma população de células manipuladas por rna, para fornecer imunidade antidoença em um indivíduo, para tratar ou prevenir uma doença associada à expressão de um antígeno, e, uso
|
|
EP3692063A1
(en)
|
2017-10-03 |
2020-08-12 |
Juno Therapeutics, Inc. |
Hpv-specific binding molecules
|
|
CN111479830A
(zh)
*
|
2017-10-10 |
2020-07-31 |
国立大学法人广岛大学 |
使用铂talen的t细胞受体的完全取代技术
|
|
EP3702454A4
(en)
*
|
2017-10-10 |
2021-08-04 |
Hiroshima University |
METHOD FOR GENERATING ANTIGEN-SPECIFIC REGULATORY T-CELLS (TREG) WITH EFFECTOR T-CELL (TEFF) ANTIGEN RECEPTORS
|
|
US11795443B2
(en)
|
2017-10-16 |
2023-10-24 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
|
JP7420712B2
(ja)
|
2017-10-25 |
2024-01-23 |
ピボット バイオ， インコーポレイテッド |
窒素を固定する操作された微生物を改良するための方法および組成物
|
|
US12151988B2
(en)
|
2017-10-25 |
2024-11-26 |
Pivot Bio, Inc. |
Gene targets for nitrogen fixation targeting for improving plant traits
|
|
WO2019084552A1
(en)
|
2017-10-27 |
2019-05-02 |
The Regents Of The University Of California |
TARGETED REPLACEMENT OF ENDOGENIC T CELL RECEPTORS
|
|
RU2020116585A
(ru)
*
|
2017-10-30 |
2021-12-01 |
Пэкт Фарма, Инк. |
Редактирование гена первичных клеток
|
|
BR112020008568A2
(pt)
*
|
2017-11-09 |
2020-10-06 |
Sangamo Therapeutics, Inc. |
modificação genética de gene de proteína contendo sh2 indutível por citoquina (cish)
|
|
US11738047B2
(en)
|
2017-12-12 |
2023-08-29 |
The Trustees Of The University Of Pennsylvania |
Genetically modified immune cells targeting NY-ESO-1 and methods of use thereof
|
|
SG11202003907WA
(en)
|
2017-12-14 |
2020-05-28 |
Flodesign Sonics Inc |
Acoustic transducer drive and controller
|
|
WO2019118949A1
(en)
|
2017-12-15 |
2019-06-20 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
AU2019206443A1
(en)
*
|
2018-01-10 |
2020-07-23 |
Cmc Icos Biologics, Inc. |
Bidirectional CHEFl vectors
|
|
AU2019216982B2
(en)
*
|
2018-02-11 |
2024-07-04 |
Memorial Sloan-Kettering Cancer Center |
Non-HLA restricted T cell receptors and uses thereof
|
|
SG11202007697VA
(en)
|
2018-02-15 |
2020-09-29 |
Memorial Sloan Kettering Cancer Center |
Foxp3 targeting agent compositions and methods of use for adoptive cell therapy
|
|
SG11202009761YA
(en)
|
2018-04-02 |
2020-10-29 |
Pact Pharma Inc |
Peptide-mhc compacts
|
|
CN112566698A
(zh)
|
2018-04-05 |
2021-03-26 |
朱诺治疗学股份有限公司 |
T细胞受体和表达该t细胞受体的工程化细胞
|
|
AU2019247199A1
(en)
|
2018-04-05 |
2020-10-15 |
Editas Medicine, Inc. |
T cells expressing a recombinant receptor, related polynucleotides and methods
|
|
EP3775238A1
(en)
*
|
2018-04-05 |
2021-02-17 |
Juno Therapeutics, Inc. |
Methods of producing cells expressing a recombinant receptor and related compositions
|
|
JP7304888B2
(ja)
|
2018-04-12 |
2023-07-07 |
プレシジョン バイオサイエンシズ，インク． |
ヒトｔ細胞受容体アルファ定常領域遺伝子に特異性を有する最適化された操作されたヌクレアーゼ
|
|
US20200208177A1
(en)
*
|
2018-04-18 |
2020-07-02 |
Ligandal, Inc. |
Methods and compositions for genome editing
|
|
EP3790629A1
(en)
|
2018-05-11 |
2021-03-17 |
CRISPR Therapeutics AG |
Methods and compositions for treating cancer
|
|
US12157760B2
(en)
|
2018-05-23 |
2024-12-03 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
EP3813511A4
(en)
|
2018-06-27 |
2022-08-03 |
Pivot Bio, Inc. |
GUIDED MICROBIAL REMODELING, PLATFORM FOR RATIONAL IMPROVEMENT OF MICROBIAL SPECIES FOR AGRICULTURE
|
|
EP3814302A4
(en)
|
2018-06-27 |
2022-06-29 |
Pivot Bio, Inc. |
Agricultural compositions comprising remodeled nitrogen fixing microbes
|
|
EP3820495A4
(en)
|
2018-07-09 |
2022-07-20 |
The Broad Institute Inc. |
RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES
|
|
US12391624B2
(en)
|
2018-07-11 |
2025-08-19 |
Pivot Bio, Inc. |
Temporally and spatially targeted dynamic nitrogen delivery by remodeled microbes
|
|
JP7250031B2
(ja)
*
|
2018-09-25 |
2023-03-31 |
公益財団法人微生物化学研究会 |
新規ウイルスベクターおよびその製造方法と使用方法
|
|
MX2021004214A
(es)
*
|
2018-10-16 |
2021-07-15 |
Intellia Therapeutics Inc |
Composiciones y metodos de inmunoterapia.
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
GB201817821D0
(en)
*
|
2018-10-31 |
2018-12-19 |
Ospedale San Raffaele Srl |
TCR and peptides
|
|
WO2020128618A2
(en)
|
2018-12-18 |
2020-06-25 |
Braskem S.A. |
Co-production pathway for 3-hp and acetyl-coa derivatives from malonate semialdehyde
|
|
US20220017911A1
(en)
|
2018-12-21 |
2022-01-20 |
Pivot Bio, Inc. |
Methods, compositions, and media for improving plant traits
|
|
EP3880807A2
(en)
|
2018-12-28 |
2021-09-22 |
Braskem S.A. |
Modulation of carbon flux through the meg and c3 pathways for the improved production of monoethylene glycol and c3 compounds
|
|
US12421519B2
(en)
|
2019-01-07 |
2025-09-23 |
Pivot Bio, Inc. |
Plant colonization assays using natural microbial barcodes
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
MX2021009640A
(es)
|
2019-02-12 |
2021-10-13 |
Pact Pharma Inc |
Composiciones y metodos para la identificacion de celulas t especificas de antigenos.
|
|
CN113748211A
(zh)
|
2019-03-01 |
2021-12-03 |
布拉斯科公司 |
用于4-羟甲基糠醛及其衍生物的体内合成的方法
|
|
EP3942043A2
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
WO2020190363A1
(en)
|
2019-03-19 |
2020-09-24 |
Massachusetts Institute Of Technology |
Control of nitrogen fixation in rhizobia that associate with cereals
|
|
WO2020206248A1
(en)
|
2019-04-03 |
2020-10-08 |
Precision Biosciences, Inc. |
Genetically-modified immune cells comprising a microrna-adapted shrna (shrnamir)
|
|
JP7715636B2
(ja)
|
2019-04-04 |
2025-07-30 |
ブラスケム エス．エー． |
第二世代の糖から化学物質を生成するためのキシロースおよびグルコースの同時消費のための代謝工学
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
CN114364788A
(zh)
|
2019-04-24 |
2022-04-15 |
皮沃特生物股份有限公司 |
用于靶向固氮以改良植物性状的基因靶标
|
|
CN114008221A
(zh)
|
2019-04-25 |
2022-02-01 |
皮沃特生物股份有限公司 |
用于分离和表征由化学诱变产生的泌铵突变体库的高通量方法
|
|
AU2020267057A1
(en)
|
2019-04-30 |
2021-11-18 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19
|
|
JP2022533713A
(ja)
|
2019-05-21 |
2022-07-25 |
サンガモ セラピューティクス， インコーポレイテッド |
調節性ｔ細胞における制御された導入遺伝子発現
|
|
WO2021016608A1
(en)
|
2019-07-25 |
2021-01-28 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
AU2020333851A1
(en)
|
2019-08-20 |
2022-03-31 |
Precision Biosciences, Inc. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
|
CN110484523A
(zh)
*
|
2019-09-06 |
2019-11-22 |
上海斯丹赛生物技术有限公司 |
一种锌指核酸酶及其应用
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
US20240398862A1
(en)
*
|
2019-10-15 |
2024-12-05 |
The Regents Of The University Of California |
Gene targets for manipulating t cell behavior
|
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
WO2021221690A1
(en)
|
2020-05-01 |
2021-11-04 |
Pivot Bio, Inc. |
Modified bacterial strains for improved fixation of nitrogen
|
|
AU2020445067A1
(en)
|
2020-05-01 |
2022-12-01 |
Pivot Bio, Inc. |
Measurement of nitrogen fixation and incorporation
|
|
CA3172322A1
(en)
|
2020-05-01 |
2021-11-04 |
Karsten TEMME |
Modified bacterial strains for improved fixation of nitrogen
|
|
WO2021222643A1
(en)
|
2020-05-01 |
2021-11-04 |
Pivot Bio, Inc. |
Stable liquid formulations for nitrogen-fixing microorganisms
|
|
BR112022022603A2
(pt)
|
2020-05-08 |
2023-01-17 |
Broad Inst Inc |
Métodos e composições para edição simultânea de ambas as fitas de sequência alvo de nucleotídeos de fita dupla
|
|
EP4149245A2
(en)
|
2020-05-13 |
2023-03-22 |
Pivot Bio, Inc. |
De-repression of nitrogen fixation in gram-positive microorganisms
|
|
WO2021260186A1
(en)
|
2020-06-26 |
2021-12-30 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
US20260028412A1
(en)
|
2020-08-10 |
2026-01-29 |
Precision Biosciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
EP4284823A1
(en)
|
2021-01-28 |
2023-12-06 |
Precision BioSciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
WO2022187406A1
(en)
|
2021-03-03 |
2022-09-09 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and a dgk inhibitor
|
|
AU2022301301A1
(en)
|
2021-07-02 |
2023-12-14 |
Pivot Bio, Inc. |
Genetically-engineered bacterial strains for improved fixation of nitrogen
|
|
IL311570A
(en)
|
2021-10-14 |
2024-05-01 |
Arsenal Biosciences Inc |
Immune cells with common expression chain and logic gate systems
|
|
JP2024539291A
(ja)
*
|
2021-10-25 |
2024-10-28 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
神経膠芽腫を治療するための方法および組成物
|
|
WO2023081767A1
(en)
|
2021-11-05 |
2023-05-11 |
Precision Biosciences, Inc. |
Methods for immunotherapy
|
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
|
WO2023122805A1
(en)
|
2021-12-20 |
2023-06-29 |
Vestaron Corporation |
Sorbitol driven selection pressure method
|
|
WO2023201133A1
(en)
|
2022-04-14 |
2023-10-19 |
Board Of Regents Of The University Of Nebraska |
Cell therapy for alzheimer's disease
|
|
WO2024054944A1
(en)
|
2022-09-08 |
2024-03-14 |
Juno Therapeutics, Inc. |
Combination of a t cell therapy and continuous or intermittent dgk inhibitor dosing
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
WO2024137259A1
(en)
|
2022-12-23 |
2024-06-27 |
Pivot Bio, Inc. |
Combination of various nitrogen fixing bacteria with various biological products to achieve synergistic effects
|
|
WO2024148167A1
(en)
|
2023-01-05 |
2024-07-11 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for the human t cell receptor alpha constant region gene
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
WO2025155521A1
(en)
|
2024-01-18 |
2025-07-24 |
Pivot Bio, Inc. |
Host cells for enhanced plant growth
|
|
WO2025155518A1
(en)
|
2024-01-18 |
2025-07-24 |
Pivot Bio, Inc. |
Host cells for enhanced plant growth
|
|
WO2026025092A1
(en)
|
2024-07-26 |
2026-01-29 |
Juno Therapeutics, Inc. |
Synthetic promoters for t cell expression
|