CN105208866B - 使用工程化锌指蛋白核酸酶靶向断裂t细胞受体基因 - Google Patents

使用工程化锌指蛋白核酸酶靶向断裂t细胞受体基因 Download PDF

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CN105208866B
CN105208866B CN201480020893.4A CN201480020893A CN105208866B CN 105208866 B CN105208866 B CN 105208866B CN 201480020893 A CN201480020893 A CN 201480020893A CN 105208866 B CN105208866 B CN 105208866B
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cells
tcr
gene
cell
domain
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CN105208866A (zh
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P·D·格雷戈里
M·C·霍尔姆斯
D·帕斯乔恩
张雷
M·C·伯尼尼
P·格诺韦塞
Z·马格纳尼
S·马斯塔格里奥
L·那尔蒂尼
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Ospedale San Raffaele SRL
Sangamo Therapeutics Inc
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Ospedale San Raffaele SRL
Sangamo Therapeutics Inc
Sangamo Biosciences Inc
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CN201480020893.4A 2013-03-21 2014-03-20 使用工程化锌指蛋白核酸酶靶向断裂t细胞受体基因 Active CN105208866B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361804076P 2013-03-21 2013-03-21
US61/804,076 2013-03-21
PCT/US2014/031360 WO2014153470A2 (en) 2013-03-21 2014-03-20 Targeted disruption of t cell receptor genes using engineered zinc finger protein nucleases

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CN105208866B true CN105208866B (zh) 2018-11-23

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US (2) US9937207B2 (enExample)
EP (1) EP2975942B1 (enExample)
JP (1) JP6346266B2 (enExample)
CN (1) CN105208866B (enExample)
AU (1) AU2014235968B2 (enExample)
CA (1) CA2906970C (enExample)
HK (1) HK1218232A1 (enExample)
IL (1) IL241583B (enExample)
WO (1) WO2014153470A2 (enExample)

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