SG11202009761YA - Peptide-mhc compacts - Google Patents
Peptide-mhc compactsInfo
- Publication number
- SG11202009761YA SG11202009761YA SG11202009761YA SG11202009761YA SG11202009761YA SG 11202009761Y A SG11202009761Y A SG 11202009761YA SG 11202009761Y A SG11202009761Y A SG 11202009761YA SG 11202009761Y A SG11202009761Y A SG 11202009761YA SG 11202009761Y A SG11202009761Y A SG 11202009761YA
- Authority
- SG
- Singapore
- Prior art keywords
- compacts
- mhc
- peptide
- mhc compacts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862651639P | 2018-04-02 | 2018-04-02 | |
| PCT/US2019/025415 WO2019195310A1 (en) | 2018-04-02 | 2019-04-02 | Peptide-mhc compacts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202009761YA true SG11202009761YA (en) | 2020-10-29 |
Family
ID=68101178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202009761YA SG11202009761YA (en) | 2018-04-02 | 2019-04-02 | Peptide-mhc compacts |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10875905B2 (en) |
| JP (1) | JP2021520212A (en) |
| KR (1) | KR20200138334A (en) |
| CN (1) | CN112334480A (en) |
| AU (3) | AU2019248644A1 (en) |
| CA (1) | CA3095741A1 (en) |
| IL (1) | IL277722A (en) |
| RU (1) | RU2020135720A (en) |
| SG (1) | SG11202009761YA (en) |
| WO (1) | WO2019195310A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11513113B2 (en) * | 2019-02-12 | 2022-11-29 | Pact Pharma, Inc. | Compositions and methods for identification of antigen specific T cells |
| WO2020223478A1 (en) | 2019-05-01 | 2020-11-05 | Pact Pharma, Inc. | Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy |
| US20230212259A1 (en) * | 2020-02-21 | 2023-07-06 | 3T Biosciences, Inc. | Yeast display libraries, associated compositions, and associate methods of use |
| WO2021195411A1 (en) * | 2020-03-25 | 2021-09-30 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides with conjugation sites and methods of use thereof |
| CN112852748B (en) * | 2020-04-16 | 2023-11-21 | 成都仕康美生物科技有限公司 | Chimeric antigen receptor targeting HLA-A, coding gene, CAR-Tregs cell, preparation method and application thereof |
| CN113774074A (en) * | 2020-06-05 | 2021-12-10 | 复旦大学 | Peptide fragment-based targeted proteome accurate quantification method |
| WO2022236102A1 (en) * | 2021-05-07 | 2022-11-10 | Institute For Systems Biology | Single chain trimer mhc class i nucleic acids and proteins and methods of use |
| CA3222120A1 (en) | 2021-06-11 | 2022-12-15 | Bhamini PURANDARE | Methods of assessing cell products |
| WO2023064242A1 (en) * | 2021-10-12 | 2023-04-20 | Pact Pharma, Inc. | Compositions and methods for isolating t cell receptors (tcrs) and cells expressing the same |
| WO2023205728A2 (en) * | 2022-04-21 | 2023-10-26 | Institute For Systems Biology | Soluble single-chain dimers from cleavable single chain trimers |
| WO2023225294A1 (en) * | 2022-05-20 | 2023-11-23 | 10X Genomics, Inc. | Improved major histocompatibility complex molecules |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007203607A1 (en) * | 2000-03-27 | 2007-08-23 | Technion Research And Development Foundation | Single Chain Class I Major Histo-Compatibility Complexes, Constructs Encoding Same and Methods of Generating Same |
| US8895020B2 (en) * | 2002-04-19 | 2014-11-25 | Washington University | Single chain trimers and uses therefor |
| US20080286312A1 (en) * | 2002-06-12 | 2008-11-20 | Gavish-Galilee Bio Applications Ltd. | Membrane-anchored beta2 microglobulincovalently linked to MHC class I peptide epitopes |
| CA2526120A1 (en) | 2003-06-03 | 2005-02-24 | Cell Genesys, Inc. | Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site |
| US20050042218A1 (en) * | 2003-07-10 | 2005-02-24 | Vaccinex, Inc. | MHC class I - peptide-antibody conjugates with modified beta2-microglobulin |
| US8992937B2 (en) | 2006-08-28 | 2015-03-31 | Washington University | Disulfide trap MHC class I molecules and uses therefor |
| US9540657B2 (en) | 2012-05-25 | 2017-01-10 | California Institute Of Technology | Expression of secreted and cell-surface polypeptides |
| CA2906970C (en) | 2013-03-21 | 2021-05-18 | Ospedale San Raffaele Srl | Targeted disruption of t cell receptor genes using engineered zinc finger protein nucleases |
| WO2015153969A1 (en) * | 2014-04-04 | 2015-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for t cell receptors |
| EP3215168B1 (en) | 2014-10-31 | 2023-08-02 | The Trustees of the University of Pennsylvania | Altering gene expression in modified t cells and uses thereof |
| EP3215164A1 (en) | 2014-11-03 | 2017-09-13 | Immures S.r.l. | T cell receptors |
| AU2016333886B2 (en) | 2015-10-05 | 2020-10-08 | Precision Biosciences, Inc. | Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene |
| EP3756682B8 (en) | 2015-10-05 | 2022-04-27 | Precision Biosciences, Inc. | Genetically-modified cells comprising a modified human t cell receptor alpha constant region gene |
| EP3426690A4 (en) | 2016-03-11 | 2019-10-09 | Bluebird Bio, Inc. | Genome edited immune effector cells |
| WO2018165475A1 (en) | 2017-03-08 | 2018-09-13 | California Institute Of Technology | Pairing antigen specificity of a t cell with t cell receptor sequences |
| CN110573630A (en) * | 2017-03-24 | 2019-12-13 | 小利兰·斯坦福大学托管委员会 | Antigen discovery of T cell receptors isolated from patient tumors that recognize wild-type antigens and potent peptide mimotopes |
| SG11202003798TA (en) | 2017-10-27 | 2020-05-28 | Univ California | Targeted replacement of endogenous t cell receptors |
-
2019
- 2019-04-02 CN CN201980037146.4A patent/CN112334480A/en active Pending
- 2019-04-02 JP JP2020554413A patent/JP2021520212A/en active Pending
- 2019-04-02 SG SG11202009761YA patent/SG11202009761YA/en unknown
- 2019-04-02 KR KR1020207031104A patent/KR20200138334A/en unknown
- 2019-04-02 WO PCT/US2019/025415 patent/WO2019195310A1/en unknown
- 2019-04-02 RU RU2020135720A patent/RU2020135720A/en unknown
- 2019-04-02 CA CA3095741A patent/CA3095741A1/en active Pending
- 2019-04-02 AU AU2019248644A patent/AU2019248644A1/en not_active Abandoned
- 2019-11-08 US US16/679,025 patent/US10875905B2/en active Active
-
2020
- 2020-10-01 IL IL277722A patent/IL277722A/en unknown
- 2020-11-18 US US16/951,925 patent/US20210070834A1/en active Pending
-
2023
- 2023-11-16 AU AU2023266338A patent/AU2023266338B1/en active Active
-
2024
- 2024-04-04 AU AU2024202172A patent/AU2024202172A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2024202172A1 (en) | 2024-05-02 |
| CN112334480A (en) | 2021-02-05 |
| US20210070834A1 (en) | 2021-03-11 |
| RU2020135720A (en) | 2022-05-04 |
| WO2019195310A1 (en) | 2019-10-10 |
| EP3774874A1 (en) | 2021-02-17 |
| CA3095741A1 (en) | 2019-10-10 |
| KR20200138334A (en) | 2020-12-09 |
| AU2019248644A1 (en) | 2020-10-22 |
| IL277722A (en) | 2020-11-30 |
| US20200062819A1 (en) | 2020-02-27 |
| JP2021520212A (en) | 2021-08-19 |
| US10875905B2 (en) | 2020-12-29 |
| AU2023266338B1 (en) | 2024-01-11 |
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