JP2016503065A5 - - Google Patents
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- JP2016503065A5 JP2016503065A5 JP2015549784A JP2015549784A JP2016503065A5 JP 2016503065 A5 JP2016503065 A5 JP 2016503065A5 JP 2015549784 A JP2015549784 A JP 2015549784A JP 2015549784 A JP2015549784 A JP 2015549784A JP 2016503065 A5 JP2016503065 A5 JP 2016503065A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- sequence shown
- tau
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261745410P | 2012-12-21 | 2012-12-21 | |
| US61/745,410 | 2012-12-21 | ||
| PCT/US2013/076952 WO2014100600A2 (en) | 2012-12-21 | 2013-12-20 | Human anti-tau antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503065A JP2016503065A (ja) | 2016-02-01 |
| JP2016503065A5 true JP2016503065A5 (enExample) | 2016-09-01 |
| JP6284548B2 JP6284548B2 (ja) | 2018-02-28 |
Family
ID=49920689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015549784A Expired - Fee Related JP6284548B2 (ja) | 2012-12-21 | 2013-12-20 | ヒト抗タウ抗体 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US9598484B2 (enExample) |
| EP (2) | EP2935326B1 (enExample) |
| JP (1) | JP6284548B2 (enExample) |
| KR (1) | KR102234324B1 (enExample) |
| CN (2) | CN111205368B (enExample) |
| AU (1) | AU2013361107B2 (enExample) |
| BR (1) | BR112015014751A8 (enExample) |
| CA (1) | CA2896066C (enExample) |
| CY (1) | CY1123518T1 (enExample) |
| DK (1) | DK2935326T3 (enExample) |
| EA (1) | EA035932B1 (enExample) |
| ES (1) | ES2816700T3 (enExample) |
| HR (1) | HRP20201422T1 (enExample) |
| HU (1) | HUE051320T2 (enExample) |
| IL (1) | IL239556B (enExample) |
| LT (1) | LT2935326T (enExample) |
| MX (1) | MX2015008024A (enExample) |
| MY (1) | MY184251A (enExample) |
| PH (2) | PH12015501420A1 (enExample) |
| PL (1) | PL2935326T3 (enExample) |
| PT (1) | PT2935326T (enExample) |
| RS (1) | RS60899B1 (enExample) |
| SG (2) | SG11201504822VA (enExample) |
| SI (1) | SI2935326T1 (enExample) |
| SM (1) | SMT202000512T1 (enExample) |
| WO (1) | WO2014100600A2 (enExample) |
| ZA (1) | ZA201504898B (enExample) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2627672T (lt) | 2010-10-11 | 2018-12-10 | Biogen International Neuroscience Gmbh | Žmogaus antikūnai prieš tau baltymą |
| EP2870176A4 (en) | 2012-07-03 | 2016-09-28 | Univ Washington | ANTIBODIES DIRECTED AGAINST TAU |
| US12024568B2 (en) | 2012-09-13 | 2024-07-02 | Cornell University | Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies |
| WO2014165271A2 (en) | 2013-03-13 | 2014-10-09 | Neotope Biosciences Limited | Tau immunotherapy |
| US20160355573A1 (en) * | 2013-09-05 | 2016-12-08 | Cornell University | Gene therapy for alzheimer's and other neurodegenerative diseases and conditions |
| CA2952741A1 (en) | 2014-06-26 | 2015-12-30 | Janssen Vaccines & Prevention B.V. | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| ZA201608812B (en) * | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| TWI734975B (zh) | 2014-06-27 | 2021-08-01 | 美商Ｃ２Ｎ醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| DE102014013571A1 (de) * | 2014-09-18 | 2016-03-24 | Aj Roboscreen Gmbh | Monoklonaler Antikörper gegen humanes TAU-Protein |
| EP3221349B1 (en) * | 2014-11-19 | 2020-11-04 | Axon Neuroscience SE | Humanized tau antibodies in alzheimer's disease |
| US10202444B2 (en) | 2015-02-24 | 2019-02-12 | Rpeptide, Llc | Anti-tau antibodies |
| AR103713A1 (es) * | 2015-02-26 | 2017-05-31 | Lilly Co Eli | Anticuerpos contra tau y sus usos |
| NZ775762A (en) | 2015-06-05 | 2025-02-28 | Genentech Inc | Anti-tau antibodies and methods of use |
| CA2991264C (en) | 2015-07-06 | 2023-10-10 | Ucb Biopharma Sprl | Tau-binding antibodies |
| SG10202010735PA (en) | 2015-07-06 | 2020-11-27 | UCB Biopharma SRL | Tau-binding antibodies |
| PL3430397T3 (pl) | 2016-03-14 | 2022-04-04 | Biogen International Neuroscience Gmbh | Oznaczenie fagocytozy zależnej od przeciwciał do wiarygodnych pomiarów wychwytu zagregowanych białek |
| MX2018013384A (es) * | 2016-05-02 | 2019-02-28 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau. |
| EP3452507B1 (en) | 2016-05-02 | 2022-10-19 | Prothena Biosciences Limited | Tau immunotherapy |
| US10906964B2 (en) * | 2016-05-02 | 2021-02-02 | Prothena Biosciences Limited | Antibodies recognizing tau |
| MX2018015022A (es) | 2016-06-07 | 2019-08-14 | Biogen Int Neuroscience Gmbh | Métodos para el tratamiento de la enfermedad de alzheimer. |
| MA45715A (fr) | 2016-07-25 | 2019-05-29 | Biogen Ma Inc | Anticorps anti-hspa5 (grp78) et leurs utilisations |
| JP6949102B2 (ja) | 2016-08-09 | 2021-10-13 | イーライ リリー アンド カンパニー | 併用療法 |
| EP3551655A2 (en) * | 2016-12-07 | 2019-10-16 | Genentech, Inc. | Anti-tau antibodies and methods of their use |
| EP3551220B1 (en) * | 2016-12-07 | 2025-01-29 | Genentech, Inc. | Anti-tau antibodies and methods of use |
| US20200031895A1 (en) | 2016-12-16 | 2020-01-30 | Biogen Ma Inc. | Stabilized proteolytically activated growth differentiation factor 11 |
| CA3053379A1 (en) | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Anti-tau antibodies and methods of use thereof |
| JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
| EP3602046A1 (en) * | 2017-03-28 | 2020-02-05 | Janssen Vaccines & Prevention B.V. | Methods for detection of tau protein aggregation modulating compounds |
| CN117205311A (zh) | 2017-03-28 | 2023-12-12 | 基因泰克公司 | 治疗神经退行性疾病的方法 |
| SG11201910066QA (en) * | 2017-05-02 | 2019-11-28 | Prothena Biosciences Ltd | Antibodies recognizing tau |
| JP6851549B2 (ja) | 2017-10-16 | 2021-03-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗タウ抗体及びその使用 |
| WO2019133799A1 (en) * | 2017-12-29 | 2019-07-04 | University Of Florida Research Foundation | Monoclonal antibodies targeting microtubule-binding domain of tau protein |
| WO2019171258A1 (en) * | 2018-03-05 | 2019-09-12 | Janssen Pharmaceutica Nv | Assays to detect neurodegeneration |
| CA3090356A1 (en) * | 2018-03-11 | 2019-09-19 | Koorosh Shahpasand | Conformation-independent antibodies against neurotoxic tau proteins |
| EP3829634A1 (en) | 2018-07-31 | 2021-06-09 | Eli Lilly and Company | Combination therapy |
| BR112021006123A2 (pt) * | 2018-10-19 | 2021-07-20 | Janssen Vaccines & Prevention B.V. | anticorpos anti-sinucleína |
| MA54070A (fr) | 2018-10-29 | 2021-09-08 | Biogen Ma Inc | Variants fc5 humanisés et stabilisés pour l'amélioration du transport à travers la barrière hémato-encéphalique |
| SG11202104549TA (en) * | 2018-11-08 | 2021-05-28 | Prothena Biosciences Ltd | Antibodies recognizing tau |
| KR102905634B1 (ko) * | 2019-05-31 | 2025-12-30 | 일라이 릴리 앤드 캄파니 | 인간 타우를 표적화하는 화합물 및 방법 |
| WO2020252394A2 (en) * | 2019-06-13 | 2020-12-17 | Arizona Board Of Regents On Behalf Of Arizona State University | Targets and methods of diagnosing, monitoring and treating frontotemporal dementia |
| WO2021012176A1 (en) * | 2019-07-23 | 2021-01-28 | Shanghaitech University | Asic1 channel antagonist antibody |
| TWI832183B (zh) | 2019-08-06 | 2024-02-11 | 香港商新旭生技股份有限公司 | 結合至病理性tau種類之抗體及其用途 |
| US11919280B2 (en) * | 2019-10-25 | 2024-03-05 | Toyobo Co., Ltd. | Laser-printable film and packaging in which same is used |
| CN116723856A (zh) | 2020-06-25 | 2023-09-08 | 默沙东有限责任公司 | 靶向丝氨酸413处磷酸化的tau的高亲和力抗体 |
| GB202010652D0 (en) * | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| AU2021367952A1 (en) * | 2020-10-26 | 2023-06-08 | Sola Biosciences Llc | Compositions and methods for the treatment of alzheimer's disease |
| KR20230157296A (ko) * | 2020-12-16 | 2023-11-16 | 보이저 테라퓨틱스, 인크. | 타우 결합 화합물 |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| WO2023028591A1 (en) | 2021-08-27 | 2023-03-02 | Genentech, Inc. | Methods of treating tau pathologies |
| CA3239708A1 (en) | 2021-12-03 | 2023-06-08 | Aubin MICHALON | Novel potency assay for antibody-based drugs and useful means therefor |
| CN118871989A (zh) | 2022-03-14 | 2024-10-29 | 基因泰克公司 | 基于语音分析来预测神经退行性疾病 |
| KR20250026248A (ko) | 2022-06-21 | 2025-02-25 | 제넨테크, 인크. | 음성 분석에 기초한 알츠하이머병(ad)의 종단적 진행 검출 |
| JP2025535203A (ja) | 2022-09-15 | 2025-10-23 | ボイジャー セラピューティクス インコーポレイテッド | タウ結合化合物 |
| WO2025090985A1 (en) * | 2023-10-27 | 2025-05-01 | Duke University | Compositions comprising chimeric antigen receptors targeting citrullinated vimentin and methods of use thereof |
| CN117946264B (zh) * | 2024-03-21 | 2024-06-04 | 江西赛基生物技术有限公司 | 一种抗Tau蛋白单克隆抗体及其应用 |
| WO2026102093A1 (en) | 2024-11-07 | 2026-05-15 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
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2013
- 2013-12-20 JP JP2015549784A patent/JP6284548B2/ja not_active Expired - Fee Related
- 2013-12-20 SM SM20200512T patent/SMT202000512T1/it unknown
- 2013-12-20 CA CA2896066A patent/CA2896066C/en active Active
- 2013-12-20 BR BR112015014751A patent/BR112015014751A8/pt not_active IP Right Cessation
- 2013-12-20 CN CN201911004609.5A patent/CN111205368B/zh not_active Expired - Fee Related
- 2013-12-20 RS RS20201060A patent/RS60899B1/sr unknown
- 2013-12-20 MY MYPI2015001581A patent/MY184251A/en unknown
- 2013-12-20 HR HRP20201422TT patent/HRP20201422T1/hr unknown
- 2013-12-20 PT PT138186374T patent/PT2935326T/pt unknown
- 2013-12-20 EA EA201591020A patent/EA035932B1/ru unknown
- 2013-12-20 SG SG11201504822VA patent/SG11201504822VA/en unknown
- 2013-12-20 SG SG10201705104UA patent/SG10201705104UA/en unknown
- 2013-12-20 MX MX2015008024A patent/MX2015008024A/es active IP Right Grant
- 2013-12-20 KR KR1020157019330A patent/KR102234324B1/ko not_active Expired - Fee Related
- 2013-12-20 HU HUE13818637A patent/HUE051320T2/hu unknown
- 2013-12-20 AU AU2013361107A patent/AU2013361107B2/en not_active Ceased
- 2013-12-20 LT LTEP13818637.4T patent/LT2935326T/lt unknown
- 2013-12-20 WO PCT/US2013/076952 patent/WO2014100600A2/en not_active Ceased
- 2013-12-20 EP EP13818637.4A patent/EP2935326B1/en active Active
- 2013-12-20 EP EP20178431.1A patent/EP3792278A3/en not_active Withdrawn
- 2013-12-20 SI SI201331780T patent/SI2935326T1/sl unknown
- 2013-12-20 PL PL13818637.4T patent/PL2935326T3/pl unknown
- 2013-12-20 DK DK13818637.4T patent/DK2935326T3/da active
- 2013-12-20 CN CN201380073531.7A patent/CN105324394B/zh not_active Expired - Fee Related
- 2013-12-20 ES ES13818637T patent/ES2816700T3/es active Active
- 2013-12-20 US US14/654,176 patent/US9598484B2/en not_active Expired - Fee Related
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2015
- 2015-06-19 PH PH12015501420A patent/PH12015501420A1/en unknown
- 2015-06-21 IL IL239556A patent/IL239556B/en active IP Right Grant
- 2015-07-08 ZA ZA201504898A patent/ZA201504898B/en unknown
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2017
- 2017-02-08 US US15/427,843 patent/US20170369560A1/en not_active Abandoned
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2018
- 2018-06-27 US US16/020,346 patent/US20190169274A1/en not_active Abandoned
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2019
- 2019-09-24 US US16/580,152 patent/US20200262895A1/en not_active Abandoned
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2020
- 2020-09-09 CY CY20201100854T patent/CY1123518T1/el unknown
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2021
- 2021-01-13 PH PH12021550083A patent/PH12021550083A1/en unknown