CY1123518T1 - Ανθρωπινα αντισωματα enanti-tau - Google Patents

Ανθρωπινα αντισωματα enanti-tau

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Publication number
CY1123518T1
CY1123518T1 CY20201100854T CY201100854T CY1123518T1 CY 1123518 T1 CY1123518 T1 CY 1123518T1 CY 20201100854 T CY20201100854 T CY 20201100854T CY 201100854 T CY201100854 T CY 201100854T CY 1123518 T1 CY1123518 T1 CY 1123518T1
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CY
Cyprus
Prior art keywords
tau
well
enanti
human
tau antibodies
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CY20201100854T
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English (en)
Inventor
Paul H. Weinreb
Feng Chen
Ellen A. Garber
Jan Grimm
Fabio Montrasio
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Biogen Ma Inc.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49920689&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1123518(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Ma Inc. filed Critical Biogen Ma Inc.
Publication of CY1123518T1 publication Critical patent/CY1123518T1/el

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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K49/00—Preparations for testing in vivo
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • C07K2317/00—Immunoglobulins specific features
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • G01N2800/00—Detection or diagnosis of diseases
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  • Health & Medical Sciences (AREA)
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Abstract

Παρέχονται νέα ανθρώπινα tau-ειδικά αντισώματα όπως επίσης θραύσματα, παράγωγα και παραλλαγές αυτών όπως επίσης μέθοδοι σχετικές με αυτά. Αποκαλύπτονται επίσης προσδιορισμοί, κιτ και στερεοί φορείς που σχετίζονται με αντισώματα ειδικά για tau. To αντίσωμα, αλυσίδα(ες) ανοσοσφαιρίνης, όπως επίσης θραύσματα δέσμευσης, παράγωγα και παραλλαγές αυτών μπορούν να χρησιμοποιηθούν σε φαρμακευτικές και διαγνωστικές συνθέσεις για tau στοχευμένη ανοσοθεραπεία και διάγνωση, αντίστοιχα.
CY20201100854T 2012-12-21 2020-09-09 Ανθρωπινα αντισωματα enanti-tau CY1123518T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261745410P 2012-12-21 2012-12-21
PCT/US2013/076952 WO2014100600A2 (en) 2012-12-21 2013-12-20 Human anti-tau antibodies

Publications (1)

Publication Number Publication Date
CY1123518T1 true CY1123518T1 (el) 2022-03-24

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ID=49920689

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CY20201100854T CY1123518T1 (el) 2012-12-21 2020-09-09 Ανθρωπινα αντισωματα enanti-tau

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EP (2) EP3792278A3 (el)
JP (1) JP6284548B2 (el)
KR (1) KR102234324B1 (el)
CN (2) CN111205368B (el)
AU (1) AU2013361107B2 (el)
BR (1) BR112015014751A8 (el)
CA (1) CA2896066C (el)
CY (1) CY1123518T1 (el)
DK (1) DK2935326T3 (el)
EA (1) EA035932B1 (el)
ES (1) ES2816700T3 (el)
HK (1) HK1216538A1 (el)
HR (1) HRP20201422T1 (el)
HU (1) HUE051320T2 (el)
IL (1) IL239556B (el)
LT (1) LT2935326T (el)
MX (1) MX2015008024A (el)
MY (1) MY184251A (el)
PH (2) PH12015501420B1 (el)
PT (1) PT2935326T (el)
RS (1) RS60899B1 (el)
SG (2) SG10201705104UA (el)
SI (1) SI2935326T1 (el)
WO (1) WO2014100600A2 (el)
ZA (1) ZA201504898B (el)

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