JP2013500940A5 - - Google Patents
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- Publication number
- JP2013500940A5 JP2013500940A5 JP2012505915A JP2012505915A JP2013500940A5 JP 2013500940 A5 JP2013500940 A5 JP 2013500940A5 JP 2012505915 A JP2012505915 A JP 2012505915A JP 2012505915 A JP2012505915 A JP 2012505915A JP 2013500940 A5 JP2013500940 A5 JP 2013500940A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- subject
- sample
- alzheimer
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23179709P | 2009-08-06 | 2009-08-06 | |
| US61/231,797 | 2009-08-06 | ||
| US28255010P | 2010-02-26 | 2010-02-26 | |
| US61/282,550 | 2010-02-26 | ||
| PCT/JP2010/004926 WO2011016239A1 (en) | 2009-08-06 | 2010-08-05 | Antibodies that specifically bind to a beta oligomers and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500940A JP2013500940A (ja) | 2013-01-10 |
| JP2013500940A5 true JP2013500940A5 (enExample) | 2014-05-15 |
| JP5599454B2 JP5599454B2 (ja) | 2014-10-01 |
Family
ID=43544148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012505915A Expired - Fee Related JP5599454B2 (ja) | 2009-08-06 | 2010-08-05 | Ａβオリゴマーに特異的に結合する抗体およびその利用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8613924B2 (enExample) |
| EP (1) | EP2462162B1 (enExample) |
| JP (1) | JP5599454B2 (enExample) |
| CN (1) | CN102596997B (enExample) |
| DK (1) | DK2462162T3 (enExample) |
| ES (1) | ES2614949T3 (enExample) |
| WO (1) | WO2011016239A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2099826B1 (en) * | 2007-01-05 | 2013-10-16 | University Of Zurich | Anti-beta-amyloid antibody and uses thereof |
| HRP20140049T1 (hr) | 2007-01-05 | 2014-02-28 | University Of Zürich | Anti beta-amiloid antitijela i njihova upotreba |
| EP2210901A4 (en) * | 2007-10-19 | 2012-04-25 | Immunas Pharma Inc | FOR THE SPECIFIC BINDING TO AN OLIGOMICALLY ABLE ANTIBODY AND ITS USE |
| EP3121277B1 (en) | 2008-02-08 | 2018-04-11 | Immunas Pharma, Inc. | Antibody capable of binding specifically to ab-oligomer, and use thereof |
| US20110182809A1 (en) * | 2008-07-09 | 2011-07-28 | University Of Zurich | Method of Promoting Neurogenesis |
| US9085614B2 (en) | 2008-08-01 | 2015-07-21 | Immunas Pharma, Inc. | Antibodies that specifically bind to Aβ oligomers and uses thereof |
| EP3521309A1 (en) | 2008-12-19 | 2019-08-07 | Biogen International Neuroscience GmbH | Human anti-alpha-synuclein antibodies |
| WO2010119704A1 (en) | 2009-04-17 | 2010-10-21 | Immunas Pharma, Inc. | Antibodies that specifically bind to a beta oligomers and use thereof |
| ES2624835T3 (es) * | 2009-08-06 | 2017-07-17 | Immunas Pharma, Inc. | Anticuerpos que se unen específicamente a los oligómeros A beta y uso de los mismos |
| US9320793B2 (en) * | 2010-07-14 | 2016-04-26 | Acumen Pharmaceuticals, Inc. | Method for treating a disease associated with soluble, oligomeric species of amyloid beta 1-42 |
| MX357193B (es) | 2011-06-23 | 2018-06-29 | Univ Zuerich | Moleculas de union anti-alfa sinucleina. |
| US9588129B2 (en) * | 2013-03-15 | 2017-03-07 | Amira Medical Technologies Inc. | Methods for analyzing blood to detect diseases associated with abnormal protein aggregation |
| JP2017536102A (ja) * | 2014-10-16 | 2017-12-07 | ジェネンテック， インコーポレイテッド | 抗アルファ−シヌクレイン抗体及び使用方法 |
| MA41115A (fr) | 2014-12-02 | 2017-10-10 | Biogen Int Neuroscience Gmbh | Procédé de traitement de la maladie d'alzheimer |
| EP4233901A3 (en) | 2017-08-22 | 2023-09-06 | Biogen MA Inc. | Pharmaceutical compositions containing anti-beta amyloid antibodies |
| CN108020673A (zh) * | 2017-11-15 | 2018-05-11 | 首都医科大学宣武医院 | Aβ试剂盒、检测方法及应用 |
| CA3089653A1 (en) * | 2018-03-08 | 2019-09-12 | Phanes Therapeutics, Inc. | Anti-claudin 18.2 antibodies and uses thereof |
| RU2020135052A (ru) * | 2018-03-28 | 2022-04-29 | Аксон Ньюросайенс Се | Способы выявления и лечения болезни альцгеймера на основе антител |
| CN115028723B (zh) * | 2019-03-07 | 2023-08-29 | 瑞阳(苏州)生物科技有限公司 | 人IL-1β蛋白结合分子及其编码基因和应用 |
| MX2022002873A (es) * | 2019-09-10 | 2022-03-25 | Ac Immune Sa | Nuevas moleculas para diagnostico. |
| US12352719B2 (en) | 2019-09-20 | 2025-07-08 | KYCERA AVX Components Corporation | Somatic cell-based electrical biosensor |
| KR20230047492A (ko) * | 2020-08-18 | 2023-04-07 | 오메로스 코포레이션 | 보체 인자 d의 검출을 위한 단클론성 항체, 조성물 및 방법 |
| CN114573694B (zh) * | 2020-12-01 | 2023-09-01 | 深圳华柏生物科技有限公司 | 一种抗IL13Rα2抗体及其制备方法和用途 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
| JPH07509137A (ja) | 1992-07-24 | 1995-10-12 | セル ジェネシス，インク． | 異種抗体の生産 |
| JPH08509612A (ja) | 1993-04-26 | 1996-10-15 | ジェンファーム インターナショナル インコーポレイテッド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| CA2219486A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US20030068316A1 (en) * | 1997-02-05 | 2003-04-10 | Klein William L. | Anti-ADDL antibodies and uses thereof |
| US6218506B1 (en) | 1997-02-05 | 2001-04-17 | Northwestern University | Amyloid β protein (globular assembly and uses thereof) |
| AR022952A1 (es) | 1999-03-19 | 2002-09-04 | Smithkline Beecham Corp | ANTICUERPO MONOCLONAL DE ROEDOR ESPECIFICAMENTE NEUTRALIZANTE PARA LA INTERLEUQUINA-18 HUMANA , UN FRAGMENTO FAB NEUTRALIZANTE o FRAGMENTO F(AB')2, UNA REGION DE COMPLEMENTARIEDAD DE CADENA LIGERA DE INMONOGLOBULINA(CDR), UNA MOLECULA DE ACIDO NUCLEICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE, EL |
| AUPR617901A0 (en) | 2001-07-06 | 2001-08-02 | Pacmab Pty Ltd | Method for treating multiple myeloma |
| WO2003014162A1 (en) | 2001-08-03 | 2003-02-20 | Medical & Biological Laboratories Co., Ltd. | ANTIBODY RECOGNIZING GM1 GANGLIOSIDE-BOUND AMYLOID β-PROTEIN AND DNA ENCODING THE ANTIBODY |
| WO2010012004A2 (en) | 2008-07-25 | 2010-01-28 | The Regents Of The University Of California | Monoclonal antibodies specific for pathological amyoid aggregates common to amyloids formed from proteins of differing sequence |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US8394379B2 (en) | 2003-05-15 | 2013-03-12 | Iogenetics, Llc | Targeted cryptosporidium biocides |
| CA2572602A1 (en) * | 2004-07-02 | 2006-02-09 | Northwestern University | Monolocal antibodies that target pathological assemblies of amyloid .beta. (abeta) |
| WO2006047254A1 (en) | 2004-10-22 | 2006-05-04 | Regents Of The University Of Minnesota | Assemblies of oligomeric amyloid beta protein and uses thereof |
| NZ554725A (en) | 2004-10-25 | 2009-10-30 | Merck & Co Inc | Anti-ADDL antibodies and uses thereof |
| WO2006077471A2 (en) * | 2004-12-10 | 2006-07-27 | Novimmune S.A. | Combining therapies targeting multiple toll-like receptors and use thereof |
| EP1838349A1 (en) | 2004-12-15 | 2007-10-03 | Neuralab, Ltd. | Amyloid beta antibodies for use in improving cognition |
| CA2593846A1 (en) | 2005-01-14 | 2006-08-10 | The Regents Of The University Of California | Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders |
| ATE458754T1 (de) | 2005-03-05 | 2010-03-15 | Abbott Gmbh & Co Kg | Screening-verfahren, verfahren zur aufreinigung nichtdiffundierbarer a-beta-oligomere, selektive antikörper gegen diese nichtdiffundierbaren a- beta-oligomere und verfahren zur herstellung dieser antikörper |
| WO2006137354A1 (ja) | 2005-06-21 | 2006-12-28 | Medical & Biological Laboratories Co., Ltd. | アミロイド線維形成に対する阻害活性を有する抗体 |
| EP1749839A1 (en) | 2005-07-22 | 2007-02-07 | Novoplant GmbH | Antigen binding polypeptides against F4(K88) fimbriae |
| PL2004688T5 (pl) * | 2006-03-23 | 2014-09-30 | Bioarctic Neuroscience Ab | Ulepszone przeciwciała wobec protofibryli oraz ich zastosowania |
| US20090232801A1 (en) | 2007-05-30 | 2009-09-17 | Abbot Laboratories | Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof |
| US20100291071A1 (en) | 2008-08-01 | 2010-11-18 | Immunas Pharma, Inc. | Antibody Specific Binding to A-Beta Oligomer and the Use |
| EP2210901A4 (en) | 2007-10-19 | 2012-04-25 | Immunas Pharma Inc | FOR THE SPECIFIC BINDING TO AN OLIGOMICALLY ABLE ANTIBODY AND ITS USE |
| EP3121277B1 (en) | 2008-02-08 | 2018-04-11 | Immunas Pharma, Inc. | Antibody capable of binding specifically to ab-oligomer, and use thereof |
| US9085614B2 (en) | 2008-08-01 | 2015-07-21 | Immunas Pharma, Inc. | Antibodies that specifically bind to Aβ oligomers and uses thereof |
| WO2010119704A1 (en) | 2009-04-17 | 2010-10-21 | Immunas Pharma, Inc. | Antibodies that specifically bind to a beta oligomers and use thereof |
| ES2624835T3 (es) | 2009-08-06 | 2017-07-17 | Immunas Pharma, Inc. | Anticuerpos que se unen específicamente a los oligómeros A beta y uso de los mismos |
-
2010
- 2010-08-05 US US13/389,228 patent/US8613924B2/en not_active Expired - Fee Related
- 2010-08-05 EP EP10806239.9A patent/EP2462162B1/en not_active Not-in-force
- 2010-08-05 DK DK10806239.9T patent/DK2462162T3/en active
- 2010-08-05 WO PCT/JP2010/004926 patent/WO2011016239A1/en not_active Ceased
- 2010-08-05 CN CN201080034845.2A patent/CN102596997B/zh not_active Expired - Fee Related
- 2010-08-05 ES ES10806239.9T patent/ES2614949T3/es active Active
- 2010-08-05 JP JP2012505915A patent/JP5599454B2/ja not_active Expired - Fee Related
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