JP2014533357A5 - - Google Patents
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- Publication number
- JP2014533357A5 JP2014533357A5 JP2014540007A JP2014540007A JP2014533357A5 JP 2014533357 A5 JP2014533357 A5 JP 2014533357A5 JP 2014540007 A JP2014540007 A JP 2014540007A JP 2014540007 A JP2014540007 A JP 2014540007A JP 2014533357 A5 JP2014533357 A5 JP 2014533357A5
- Authority
- JP
- Japan
- Prior art keywords
- synuclein
- level
- subject
- antibody
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161554924P | 2011-11-02 | 2011-11-02 | |
| US61/554,924 | 2011-11-02 | ||
| PCT/US2012/062430 WO2013066818A1 (en) | 2011-11-02 | 2012-10-29 | USE OF AN ANTI-α-SYNUCLEIN ANTIBODY TO DIAGNOSE AN ELEVATED LEVEL OF α-SYNUCLEIN IN THE BRAIN |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533357A JP2014533357A (ja) | 2014-12-11 |
| JP2014533357A5 true JP2014533357A5 (enExample) | 2015-10-15 |
| JP6263473B2 JP6263473B2 (ja) | 2018-01-31 |
Family
ID=48192661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014540007A Expired - Fee Related JP6263473B2 (ja) | 2011-11-02 | 2012-10-29 | 脳における高レベルのα−シヌクレインを診断するための抗α−シヌクレイン抗体の使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20140295465A1 (enExample) |
| EP (1) | EP2773957B1 (enExample) |
| JP (1) | JP6263473B2 (enExample) |
| KR (1) | KR102036938B1 (enExample) |
| CN (2) | CN104040342A (enExample) |
| AU (1) | AU2012332814B2 (enExample) |
| BR (1) | BR112014010664A2 (enExample) |
| CA (1) | CA2854131C (enExample) |
| EA (1) | EA034213B1 (enExample) |
| IL (1) | IL232373B (enExample) |
| MX (1) | MX356797B (enExample) |
| WO (1) | WO2013066818A1 (enExample) |
| ZA (1) | ZA201403879B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102317316B (zh) | 2008-12-19 | 2014-08-13 | 帕尼玛制药股份公司 | 人抗α突触核蛋白自身抗体 |
| SI2723379T1 (sl) | 2011-06-23 | 2019-03-29 | Biogen International Neuroscience Gmbh | Molekule, ki se vežejo ma anti alfa-sinuklein |
| JP2017536102A (ja) | 2014-10-16 | 2017-12-07 | ジェネンテック， インコーポレイテッド | 抗アルファ−シヌクレイン抗体及び使用方法 |
| JP6273338B1 (ja) * | 2016-12-05 | 2018-01-31 | 磁量生技股▲ふん▼有限公司 | パーキンソン病からパーキンソン病認知症を特定する方法 |
| EP3567054A4 (en) * | 2017-01-06 | 2021-03-10 | ABL Bio Inc. | ANTI-ALPHA SYN ANTIBODIES AND USES THEREOF |
| BR112019013953A2 (pt) | 2017-01-06 | 2020-02-11 | Abl Bio Inc. | Anticorpo anti-a-syn e uso do mesmo |
| CA3051839A1 (en) | 2017-02-17 | 2018-08-23 | Bristol-Myers Squibb Company | Antibodies to alpha-synuclein and uses thereof |
| EP3725806A4 (en) | 2017-12-14 | 2022-03-30 | ABL Bio Inc. | BISPECIFIC ANTIBODIES AGAINST A-SYN/IGF1R AND ASSOCIATED USE |
| GB201803553D0 (en) | 2018-03-06 | 2018-04-18 | Univ Newcastle | Detection of pathological protein aggregation |
| WO2020009482A1 (ko) * | 2018-07-03 | 2020-01-09 | 에이비엘바이오 주식회사 | 항 알파-시누클레인 항체 및 그 용도 |
| EP3629021A1 (en) * | 2018-09-26 | 2020-04-01 | Euroimmun Medizinische Labordiagnostika AG | Diagnosis of a neuroautoimmune disease |
| KR102252879B1 (ko) * | 2019-11-15 | 2021-05-17 | 성균관대학교산학협력단 | 혈장 내 aimp2를 이용한 파킨슨 질환의 진단 방법, 이를 위한 조성물 및 이를 포함하는 키트 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| FR2686087A1 (fr) | 1992-01-13 | 1993-07-16 | Inst Nat Sante Rech Med | Nouvel antigene lymphocytaire, anticorps correspondant et leurs applications. |
| AU3117799A (en) * | 1998-03-30 | 1999-10-18 | Trustees Of The University Of Pennsylvania, The | Method of identifying, diagnosing and treating synuclein positive neurodegenerative disorders |
| WO2002004482A1 (en) * | 2000-07-07 | 2002-01-17 | Panacea Pharmaceuticals, Inc. | Methods for preventing neural tissue damage and for the treatment of alpha-synuclein diseases |
| GB0203446D0 (en) * | 2002-02-14 | 2002-04-03 | Univ Lancaster | Detection and/or monitoring of synuclein-related diseases |
| WO2007011907A2 (en) * | 2005-07-19 | 2007-01-25 | University Of Rochester | Alpha-synuclein antibodies and methods related thereto |
| WO2008081008A1 (en) | 2007-01-05 | 2008-07-10 | University Of Zurich | Method of providing disease-specific binding molecules and targets |
| CN101308144A (zh) * | 2007-05-16 | 2008-11-19 | 首都医科大学宣武医院 | 检测受试者体液内疾病相关蛋白聚合能力的方法 |
| PT2282758T (pt) * | 2008-04-29 | 2019-02-12 | Bioarctic Ab | Anticorpos e vacinas para uso em métodos terapêuticos e diagnósticos para perturbações relacionadas com a alfa-sinucleína |
| CN102317316B (zh) | 2008-12-19 | 2014-08-13 | 帕尼玛制药股份公司 | 人抗α突触核蛋白自身抗体 |
| CN101692092B (zh) * | 2009-09-24 | 2013-04-10 | 首都医科大学宣武医院 | 定量检测人血清中自体α-突触核蛋白抗体的方法 |
-
2012
- 2012-10-29 BR BR112014010664A patent/BR112014010664A2/pt not_active Application Discontinuation
- 2012-10-29 AU AU2012332814A patent/AU2012332814B2/en not_active Ceased
- 2012-10-29 US US14/355,743 patent/US20140295465A1/en not_active Abandoned
- 2012-10-29 JP JP2014540007A patent/JP6263473B2/ja not_active Expired - Fee Related
- 2012-10-29 MX MX2014005378A patent/MX356797B/es active IP Right Grant
- 2012-10-29 CN CN201280065165.6A patent/CN104040342A/zh active Pending
- 2012-10-29 EA EA201490883A patent/EA034213B1/ru unknown
- 2012-10-29 KR KR1020147014713A patent/KR102036938B1/ko not_active Expired - Fee Related
- 2012-10-29 CN CN201710252366.1A patent/CN107091931A/zh active Pending
- 2012-10-29 CA CA2854131A patent/CA2854131C/en active Active
- 2012-10-29 EP EP12846452.6A patent/EP2773957B1/en active Active
- 2012-10-29 WO PCT/US2012/062430 patent/WO2013066818A1/en not_active Ceased
-
2014
- 2014-04-30 IL IL232373A patent/IL232373B/en active IP Right Grant
- 2014-05-27 ZA ZA2014/03879A patent/ZA201403879B/en unknown
-
2017
- 2017-01-19 US US15/409,671 patent/US20180011112A1/en not_active Abandoned
-
2018
- 2018-05-16 US US15/981,691 patent/US20190094245A1/en not_active Abandoned
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