JP2020510845A5 - - Google Patents

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Publication number
JP2020510845A5
JP2020510845A5 JP2019566047A JP2019566047A JP2020510845A5 JP 2020510845 A5 JP2020510845 A5 JP 2020510845A5 JP 2019566047 A JP2019566047 A JP 2019566047A JP 2019566047 A JP2019566047 A JP 2019566047A JP 2020510845 A5 JP2020510845 A5 JP 2020510845A5
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JP
Japan
Prior art keywords
pharmaceutical composition
seq
antagonist antibody
sema4d
subject
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JP2019566047A
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English (en)
Japanese (ja)
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JP2020510845A (ja
JP7626416B2 (ja
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Priority claimed from PCT/US2018/018794 external-priority patent/WO2018156509A1/en
Publication of JP2020510845A publication Critical patent/JP2020510845A/ja
Publication of JP2020510845A5 publication Critical patent/JP2020510845A5/ja
Application granted granted Critical
Publication of JP7626416B2 publication Critical patent/JP7626416B2/ja
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JP2019566047A 2017-02-22 2018-02-20 神経変性疾患または神経炎症性疾患におけるグリア細胞活性化の早期検出方法 Active JP7626416B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762461945P 2017-02-22 2017-02-22
US62/461,945 2017-02-22
PCT/US2018/018794 WO2018156509A1 (en) 2017-02-22 2018-02-20 Early detection of glial cell activation in neurodegenerative or neuroinflammatory diseases

Publications (3)

Publication Number Publication Date
JP2020510845A JP2020510845A (ja) 2020-04-09
JP2020510845A5 true JP2020510845A5 (enExample) 2021-03-25
JP7626416B2 JP7626416B2 (ja) 2025-02-04

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ID=63253999

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019566047A Active JP7626416B2 (ja) 2017-02-22 2018-02-20 神経変性疾患または神経炎症性疾患におけるグリア細胞活性化の早期検出方法

Country Status (14)

Country Link
US (1) US20190383836A1 (enExample)
EP (1) EP3585435A4 (enExample)
JP (1) JP7626416B2 (enExample)
KR (1) KR102533921B1 (enExample)
CN (1) CN110325213A (enExample)
AU (1) AU2018225493B2 (enExample)
BR (1) BR112019017367A2 (enExample)
CA (1) CA3050328A1 (enExample)
IL (1) IL267940B2 (enExample)
MX (1) MX2019009986A (enExample)
RU (1) RU2766341C2 (enExample)
SG (1) SG11201906670PA (enExample)
WO (1) WO2018156509A1 (enExample)
ZA (1) ZA201904431B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3320920A1 (en) 2009-05-08 2018-05-16 Vaccinex, Inc. Anti-cd100 antibodies and methods for using the same
EP2766093B1 (en) 2011-10-11 2018-02-21 Vaccinex, Inc. Use of semaphorin-4d binding molecules for modulation of blood brain barrier permeability
US9708601B2 (en) 2012-04-26 2017-07-18 Vaccinex, Inc. Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
US10494440B2 (en) * 2012-05-11 2019-12-03 Vaccinex, Inc. Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
SG10201902380SA (en) 2013-06-25 2019-04-29 Vaccinex Inc Use of semaphorin-4d inhibitory molecules in combination with an immune modulating therapy to inhibit tumor growth and metastases
NZ630892A (en) 2013-10-21 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
EP3445397B1 (en) 2016-04-22 2022-11-09 Vaccinex, Inc. Integral membrane protein display on poxvirus extracellular enveloped virions
CA3032512C (en) 2016-08-02 2025-05-06 Vaccinex, Inc. IMPROVED PROCESSES FOR PRODUCING POLYNUCLEOTIDE LIBRARIES IN VACCINE VIRUS/EUKARYOTIC CELLS
CA3181833A1 (en) * 2020-06-25 2021-12-30 Vaccinex, Inc. Use of semaphorin-4d binding molecules for the treatment of rett syndrome
WO2023048726A1 (en) * 2021-09-27 2023-03-30 Vaccinex, Inc. Predictive outcome profiling for use of an anti-semaphorin-4d binding molecule to treat neurodegenerative disorders
WO2024210462A1 (ko) * 2023-04-03 2024-10-10 서울대학교산학협력단 재조합 세마포린 4d 차단항체를 유효성분으로 포함하는 쇼그렌 증후군 예방 또는 치료용 약학 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A3 (de) * 1997-07-09 2000-03-08 Hoechst Marion Roussel Deutschland GmbH Humanes und murines Semaphorin L
KR101649168B1 (ko) * 2008-05-09 2016-08-18 애브비 인코포레이티드 최종 당화 산물의 수용체(rage)에 대한 항체 및 이의 용도
EP2766093B1 (en) * 2011-10-11 2018-02-21 Vaccinex, Inc. Use of semaphorin-4d binding molecules for modulation of blood brain barrier permeability
US10494440B2 (en) * 2012-05-11 2019-12-03 Vaccinex, Inc. Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
NZ630881A (en) * 2013-10-10 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treatment of atherosclerosis
NZ630892A (en) * 2013-10-21 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
WO2017011746A1 (en) * 2015-07-15 2017-01-19 Adm Diagnostics, Llc System and methods for determining a brain condition of a patient sybject to multiple disease states

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