JP2018502840A5 - - Google Patents

Info

Publication number

JP2018502840A5

JP2018502840A5 JP2017531213A JP2017531213A JP2018502840A5 JP 2018502840 A5 JP2018502840 A5 JP 2018502840A5 JP 2017531213 A JP2017531213 A JP 2017531213A JP 2017531213 A JP2017531213 A JP 2017531213A JP 2018502840 A5 JP2018502840 A5 JP 2018502840A5

Authority

JP

Japan

Prior art keywords

seq

amino acid

acid sequence

antibody

chain variable

Prior art date

2015-12-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 238000000034 method Methods 0.000 claims 10
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• 101000800023 Homo sapiens 4F2 cell-surface antigen heavy chain Proteins 0.000 claims 8
• 239000000427 antigen Substances 0.000 claims 8
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• 102000036639 antigens Human genes 0.000 claims 8
• 229940079593 drug Drugs 0.000 claims 7
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• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
• 102100021257 Beta-secretase 1 Human genes 0.000 claims 4
• 101710150192 Beta-secretase 1 Proteins 0.000 claims 4
• 108010047041 Complementarity Determining Regions Proteins 0.000 claims 4
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