JP2015505665A5 - - Google Patents

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JP2015505665A5
JP2015505665A5 JP2014537750A JP2014537750A JP2015505665A5 JP 2015505665 A5 JP2015505665 A5 JP 2015505665A5 JP 2014537750 A JP2014537750 A JP 2014537750A JP 2014537750 A JP2014537750 A JP 2014537750A JP 2015505665 A5 JP2015505665 A5 JP 2015505665A5
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Japan
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seq
tdp
antibody
group
disease
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JP2014537750A
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Japanese (ja)
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JP2015505665A (ja
JP6240611B2 (ja
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Priority claimed from PCT/IB2012/002905 external-priority patent/WO2013061163A2/en
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Publication of JP2015505665A5 publication Critical patent/JP2015505665A5/ja
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JP2014537750A 2011-10-28 2012-10-26 Tdp−43に特異的な結合分子 Expired - Fee Related JP6240611B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161553113P 2011-10-28 2011-10-28
US61/553,113 2011-10-28
PCT/IB2012/002905 WO2013061163A2 (en) 2011-10-28 2012-10-26 Tdp-43 specific binding molecules

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017126314A Division JP6417451B2 (ja) 2011-10-28 2017-06-28 Tdp−43に特異的な結合分子

Publications (3)

Publication Number Publication Date
JP2015505665A JP2015505665A (ja) 2015-02-26
JP2015505665A5 true JP2015505665A5 (enExample) 2015-10-29
JP6240611B2 JP6240611B2 (ja) 2017-11-29

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ID=47720540

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JP2014537750A Expired - Fee Related JP6240611B2 (ja) 2011-10-28 2012-10-26 Tdp−43に特異的な結合分子
JP2017126314A Expired - Fee Related JP6417451B2 (ja) 2011-10-28 2017-06-28 Tdp−43に特異的な結合分子
JP2018174683A Expired - Fee Related JP6652609B2 (ja) 2011-10-28 2018-09-19 Tdp−43に特異的な結合分子

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017126314A Expired - Fee Related JP6417451B2 (ja) 2011-10-28 2017-06-28 Tdp−43に特異的な結合分子
JP2018174683A Expired - Fee Related JP6652609B2 (ja) 2011-10-28 2018-09-19 Tdp−43に特異的な結合分子

Country Status (18)

Country Link
US (3) US9587014B2 (enExample)
EP (2) EP2771359B1 (enExample)
JP (3) JP6240611B2 (enExample)
KR (2) KR102032080B1 (enExample)
CN (1) CN104159918B (enExample)
AU (1) AU2012327211C9 (enExample)
BR (1) BR112014010161B1 (enExample)
CA (2) CA2853412C (enExample)
CL (1) CL2014001074A1 (enExample)
EA (1) EA032003B1 (enExample)
ES (1) ES2883212T3 (enExample)
IL (2) IL232219B (enExample)
MX (2) MX357678B (enExample)
MY (1) MY167795A (enExample)
PH (1) PH12014500940A1 (enExample)
SG (1) SG11201401735WA (enExample)
WO (1) WO2013061163A2 (enExample)
ZA (1) ZA201403680B (enExample)

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JP7761373B2 (ja) * 2017-05-30 2025-10-28 ザ ユニヴァーシティ オブ ブリティッシュ コロンビア Tdp-43のrna認識モチーフ1(rrm1)中のエピトープ、およびそれらに対するミスフォールディング選択的抗体
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WO2019113711A1 (en) 2017-12-14 2019-06-20 University Of Ottawa Exosome packaging and targeted autophagy
WO2019118527A1 (en) * 2017-12-14 2019-06-20 The Johns Hopkins University Novel anti-fungal inhibitors
US11466077B2 (en) 2018-01-05 2022-10-11 Ac Immune Sa Misfolded TDP-43 binding molecules
JP7320282B2 (ja) * 2018-03-16 2023-08-03 国立大学法人滋賀医科大学 異常tdp-43を分解除去する抗体断片
SG11202008593PA (en) 2018-03-21 2020-10-29 Five Prime Therapeutics Inc ANTIBODIES BINDING TO VISTA AT ACIDIC pH
TW202019398A (zh) * 2018-06-28 2020-06-01 張翔毓 用於治療或預防構形疾病之方法及藥物篩選方法
AU2019301120A1 (en) 2018-07-11 2021-02-25 Bristol-Myers Squibb Company Antibodies binding to VISTA at acidic pH
MA54070A (fr) 2018-10-29 2021-09-08 Biogen Ma Inc Variants fc5 humanisés et stabilisés pour l'amélioration du transport à travers la barrière hémato-encéphalique
AU2019399680B2 (en) * 2018-12-14 2026-07-23 Promis Neurosciences Inc. Antibodies to misfolded TDP-43 and methods of use
CN114008073B (zh) * 2019-05-23 2025-08-12 Ac免疫有限公司 抗tdp-43结合分子及其用途
AU2020331401B2 (en) * 2019-08-12 2025-04-24 Celosia Therapeutics Pty Ltd Compositions and methods for treatment
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KR20230003067A (ko) * 2020-04-29 2023-01-05 더 유니버시티 오브 브리티쉬 콜롬비아 미스폴딩된 tdp-43에 대한 단일쇄 항체 및 인트라바디 그리고 사용 방법
US20230288432A1 (en) * 2020-07-06 2023-09-14 The Board Of Regents Of The University Of Texas System Tdp-43 biosensor cell lines
CN116615452A (zh) * 2020-08-14 2023-08-18 Ac免疫有限公司 人源化抗tdp-43结合分子及其用途
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CN112920264B (zh) * 2021-02-08 2022-07-05 武汉大学 Tdp-43蛋白的o-糖基化突变体及其应用
JP6961278B1 (ja) * 2021-03-10 2021-11-05 国立研究開発法人量子科学技術研究開発機構 生体試料中のtdp−43を測定する方法及び装置
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KR102859015B1 (ko) * 2023-07-20 2025-09-12 충북대학교 산학협력단 c­Abl에 의한 TDP­43의 특이적 인산화 분석을 통한 신경퇴행성 질환을 진단하는 방법 및 이를 이용한 신경퇴행성 질환의 치료제 스크리닝 방법
CN116875738A (zh) * 2023-07-24 2023-10-13 山东省农业科学院畜牧兽医研究所 一种鉴定牛tdp-43基因启动子活性区域的方法
WO2025059486A1 (en) * 2023-09-15 2025-03-20 Prothena Biosciences Limited Anti-tdp-43 antibodies and uses thereof
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KR20260044274A (ko) * 2024-09-23 2026-04-02 주식회사 피플바이오 Tdp-43에 특이적으로 결합하는 항체 및 이의 용도
CN119331085B (zh) * 2024-10-16 2025-03-14 中国科学院合肥物质科学研究院 沙贝冠状病毒广谱中和抗体及其应用
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