BR112014010161B1 - Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 - Google Patents

Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 Download PDF

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BR112014010161B1
BR112014010161B1 BR112014010161-2A BR112014010161A BR112014010161B1 BR 112014010161 B1 BR112014010161 B1 BR 112014010161B1 BR 112014010161 A BR112014010161 A BR 112014010161A BR 112014010161 B1 BR112014010161 B1 BR 112014010161B1
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tdp
antibody
seq
antibodies
binding
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BR112014010161-2A
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English (en)
Portuguese (pt)
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BR112014010161A2 (pt
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Roger Nitsch
Christoph Hock
Maria Grazia Barenco Montrasio
Fabio Montrasio
Jan Grimm
Jean-Luc Baeriswyl
Paul Weinreb
Janaky Coomaraswamy
Omar Quintero-Monzon
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Biogen International Neuroscience Gmbh
University Of Zurich
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Publication of BR112014010161A2 publication Critical patent/BR112014010161A2/pt
Publication of BR112014010161B1 publication Critical patent/BR112014010161B1/pt

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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BR112014010161-2A 2011-10-28 2012-10-26 Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 BR112014010161B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161553113P 2011-10-28 2011-10-28
US61/553,113 2011-10-28
PCT/IB2012/002905 WO2013061163A2 (en) 2011-10-28 2012-10-26 Tdp-43 specific binding molecules

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Publication Number Publication Date
BR112014010161A2 BR112014010161A2 (pt) 2018-09-25
BR112014010161B1 true BR112014010161B1 (pt) 2022-02-08

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EP (2) EP3964524A1 (enExample)
JP (3) JP6240611B2 (enExample)
KR (2) KR102032080B1 (enExample)
CN (1) CN104159918B (enExample)
AU (1) AU2012327211C9 (enExample)
BR (1) BR112014010161B1 (enExample)
CA (2) CA2853412C (enExample)
CL (1) CL2014001074A1 (enExample)
EA (1) EA032003B1 (enExample)
ES (1) ES2883212T3 (enExample)
IL (2) IL232219B (enExample)
MX (2) MX357678B (enExample)
MY (1) MY167795A (enExample)
PH (1) PH12014500940A1 (enExample)
SG (1) SG11201401735WA (enExample)
WO (1) WO2013061163A2 (enExample)
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