JP2015530971A5 - - Google Patents
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- JP2015530971A5 JP2015530971A5 JP2015520685A JP2015520685A JP2015530971A5 JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5 JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015520685 A JP2015520685 A JP 2015520685A JP 2015530971 A5 JP2015530971 A5 JP 2015530971A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- tau
- amino acid
- antibody
- acid sequence
- Prior art date
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261667515P | 2012-07-03 | 2012-07-03 | |
| US61/667,515 | 2012-07-03 | ||
| US201261694989P | 2012-08-30 | 2012-08-30 | |
| US61/694,989 | 2012-08-30 | ||
| PCT/US2013/049333 WO2014008404A1 (en) | 2012-07-03 | 2013-07-03 | Antibodies to tau |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018098889A Division JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530971A JP2015530971A (ja) | 2015-10-29 |
| JP2015530971A5 true JP2015530971A5 (enExample) | 2016-08-18 |
| JP6345655B2 JP6345655B2 (ja) | 2018-06-20 |
Family
ID=49882495
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015520685A Expired - Fee Related JP6345655B2 (ja) | 2012-07-03 | 2013-07-03 | タウに対する抗体 |
| JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
| JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018098889A Pending JP2018184398A (ja) | 2012-07-03 | 2018-05-23 | タウに対する抗体 |
| JP2020070416A Pending JP2020125310A (ja) | 2012-07-03 | 2020-04-09 | タウに対する抗体 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9834596B2 (enExample) |
| EP (2) | EP3838921A3 (enExample) |
| JP (3) | JP6345655B2 (enExample) |
| KR (3) | KR20150036346A (enExample) |
| CN (2) | CN108623682A (enExample) |
| AU (3) | AU2013286680B2 (enExample) |
| BR (1) | BR112014033116B1 (enExample) |
| CA (1) | CA2877397A1 (enExample) |
| HK (1) | HK1209768A1 (enExample) |
| IL (3) | IL236409B (enExample) |
| IN (1) | IN2015KN00007A (enExample) |
| MX (2) | MX359555B (enExample) |
| MY (1) | MY171473A (enExample) |
| NZ (2) | NZ739622A (enExample) |
| RU (2) | RU2018132044A (enExample) |
| SG (3) | SG10201913370PA (enExample) |
| WO (1) | WO2014008404A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150036346A (ko) | 2012-07-03 | 2015-04-07 | 워싱턴 유니버시티 | Tau에 대한 항체 |
| RS60080B1 (sr) | 2012-08-16 | 2020-05-29 | Ipierian Inc | Metodi lečenja tauopatije |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| CA2902026C (en) * | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
| JP2017512751A (ja) | 2014-02-14 | 2017-05-25 | アイピエリアン,インコーポレイティド | タウペプチド、抗タウ抗体、およびそれらの使用方法 |
| WO2015165961A1 (en) | 2014-04-29 | 2015-11-05 | Affiris Ag | Treatment and prevention of alzheimer's disease (ad) |
| ZA201608812B (en) | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| EA035530B1 (ru) * | 2014-06-26 | 2020-06-30 | Янссен Вэксинс Энд Превеншн Б.В. | Антитела и антигенсвязывающие фрагменты, которые специфично связываются с белком тау, ассоциированным с микротрубочками |
| TW202136296A (zh) * | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| BR112017006419A2 (pt) | 2014-09-30 | 2017-12-19 | Univ Washington | medições cinéticas de tau |
| MA41451A (fr) * | 2015-02-04 | 2017-12-12 | Univ Washington | Constructions anti-tau |
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| KR20250027278A (ko) * | 2015-07-06 | 2025-02-25 | 유씨비 바이오파마 에스알엘 | 타우 결합 항체 |
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| BR112018004916A2 (pt) | 2016-07-12 | 2018-12-11 | H Lundbeck As | anticorpos específicos para tau hiperfosforilada e métodos de uso dos mesmos |
| CA3032692A1 (en) | 2016-08-09 | 2018-02-15 | Eli Lilly And Company | Combination antibody therapy for the treatment of neurodegenerative diseases |
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| AU2017373884B2 (en) | 2016-12-07 | 2024-11-14 | Ac Immune Sa | Anti-tau antibodies and methods of their use |
| CR20190271A (es) | 2016-12-07 | 2019-09-03 | Genentech Inc | Anticuerpos antitau y métodos de uso |
| CN106749658B (zh) * | 2016-12-15 | 2019-11-12 | 北京师范大学 | 抑制Tau蛋白聚集的抗体型分子伴侣 |
| JP7144755B2 (ja) | 2016-12-16 | 2022-09-30 | ハー・ルンドベック・アクチエゼルスカベット | 薬剤、使用および方法 |
| US10364286B2 (en) | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| BR112019017021A2 (pt) | 2017-02-17 | 2020-04-14 | Denali Therapeutics Inc | anticorpos anti-tau e métodos de uso dos mesmos |
| US11078272B2 (en) * | 2017-03-09 | 2021-08-03 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of pediatric brain tumors with targeting of CD47 pathway |
| WO2018204546A2 (en) | 2017-05-02 | 2018-11-08 | Prothena Biosciences Limited | Antibodies recognizing tau |
| MA50397A (fr) | 2017-10-16 | 2020-08-26 | Eisai R&D Man Co Ltd | Anticorps anti-tau et leurs utilisations |
| MX2020009935A (es) * | 2018-03-23 | 2021-01-08 | Abbvie Deutschland | Formulaciones acuosas y estables de anticuerpos anti-tau. |
| US11629175B2 (en) | 2018-04-27 | 2023-04-18 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for preparing PHFS-like Tau aggregates |
| WO2020028141A1 (en) | 2018-07-31 | 2020-02-06 | Eli Lilly And Company | Combination therapy |
| CN109613242A (zh) * | 2018-11-01 | 2019-04-12 | 深圳天辰医疗科技有限公司 | 一种肌酸激酶同工酶检测试剂盒及其制备方法 |
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| SG11202108091YA (en) * | 2019-03-18 | 2021-08-30 | Regeneron Pharma | Crispr/cas screening platform to identify genetic modifiers of tau seeding or aggregation |
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| JP7595061B2 (ja) * | 2019-07-15 | 2024-12-05 | アデル,インコーポレーテッド | 抗タウ抗体およびその使用 |
| JP7780200B2 (ja) * | 2019-08-13 | 2025-12-04 | ワシントン・ユニバーシティ | Mtbrタウアイソフォームを検出する方法およびその使用 |
| CA3156678A1 (en) | 2019-10-09 | 2021-04-15 | Bluerock Therapeutics Lp | Cells with sustained transgene expression |
| EP4069734A1 (en) * | 2019-12-04 | 2022-10-12 | AC Immune SA | Novel molecules for therapy and diagnosis |
| EP4241088A1 (en) * | 2020-11-09 | 2023-09-13 | Meso Scale Technologies, LLC | Methods and kits for detecting tau |
| US20240101654A1 (en) | 2020-12-29 | 2024-03-28 | Neurimmune Ag | Human anti-tau antibodies |
| TW202304990A (zh) | 2021-03-26 | 2023-02-01 | 美商健生生物科技公司 | 針對成對螺旋絲tau之人源化抗體及其用途 |
| US20240150451A1 (en) | 2021-03-26 | 2024-05-09 | Janssen Biotech, Inc. | Anti-tau antibodies and uses thereof |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| CN119744269A (zh) * | 2022-08-23 | 2025-04-01 | 华盛顿大学 | 抗tau mtbr抗体和检测tau的切割片段的方法及其用途 |
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| WO2014096321A1 (en) | 2012-12-21 | 2014-06-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies specific to tau phosphorylated at serine 422 and uses for the treatment and diagnosis of tauopathies |
| US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
| CA2902026C (en) | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
| WO2014159244A2 (en) | 2013-03-14 | 2014-10-02 | Merck Patent Gmbh | O-GlcNAc TAU ANTIBODY AND USE THEREOF |
| AU2014240063B2 (en) | 2013-03-15 | 2019-04-11 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| RU2661111C2 (ru) | 2013-03-15 | 2018-07-11 | Ац Иммуне С.А. | Антитела к тау и способы применения |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
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2013
- 2013-07-03 KR KR20157002867A patent/KR20150036346A/ko not_active Abandoned
- 2013-07-03 CA CA2877397A patent/CA2877397A1/en not_active Abandoned
- 2013-07-03 KR KR1020207033554A patent/KR102494798B1/ko active Active
- 2013-07-03 SG SG10201913370PA patent/SG10201913370PA/en unknown
- 2013-07-03 SG SG11201408626YA patent/SG11201408626YA/en unknown
- 2013-07-03 CN CN201810507442.3A patent/CN108623682A/zh active Pending
- 2013-07-03 HK HK15110657.6A patent/HK1209768A1/xx unknown
- 2013-07-03 IN IN7KON2015 patent/IN2015KN00007A/en unknown
- 2013-07-03 MY MYPI2014704038A patent/MY171473A/en unknown
- 2013-07-03 CN CN201380045706.3A patent/CN104781278B/zh active Active
- 2013-07-03 MX MX2014016024A patent/MX359555B/es active IP Right Grant
- 2013-07-03 EP EP20199802.8A patent/EP3838921A3/en not_active Withdrawn
- 2013-07-03 RU RU2018132044A patent/RU2018132044A/ru unknown
- 2013-07-03 NZ NZ739622A patent/NZ739622A/en not_active IP Right Cessation
- 2013-07-03 EP EP13813988.6A patent/EP2870176A4/en not_active Withdrawn
- 2013-07-03 KR KR1020207002242A patent/KR20200013072A/ko not_active Ceased
- 2013-07-03 JP JP2015520685A patent/JP6345655B2/ja not_active Expired - Fee Related
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- 2013-07-03 WO PCT/US2013/049333 patent/WO2014008404A1/en not_active Ceased
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- 2013-07-03 BR BR112014033116-2A patent/BR112014033116B1/pt active IP Right Grant
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- 2014-12-19 MX MX2022000026A patent/MX2022000026A/es unknown
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2017
- 2017-06-02 US US15/612,695 patent/US20180037641A1/en not_active Abandoned
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