|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
MX368648B
(es)
|
2010-04-15 |
2019-10-09 |
Seattle Genetics Inc |
Pirrolobenzodiazepinas usadas para tratar enfermedades proliferativas.
|
|
NZ602932A
(en)
|
2010-04-15 |
2014-08-29 |
Seattle Genetics Inc |
Targeted pyrrolobenzodiazapine conjugates
|
|
MX341524B
(es)
|
2011-09-20 |
2016-08-24 |
Medimmune Ltd |
Pirrolobenzodiazepinas como compuestos pbd dimericos asimetricos para inclusion en conjugados dirigidos.
|
|
CA2850373C
(en)
|
2011-10-14 |
2019-07-16 |
Seattle Genetics, Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
|
AU2012322613B2
(en)
|
2011-10-14 |
2016-04-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and targeted conjugates
|
|
KR101891859B1
(ko)
|
2011-10-14 |
2018-08-24 |
메디뮨 리미티드 |
피롤로벤조디아제핀
|
|
EP2751110B1
(en)
|
2011-10-14 |
2017-04-19 |
MedImmune Limited |
Asymmetrical bis-(5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one) derivatives for the treatment of proliferative and autoimmune diseases
|
|
PT2906298T
(pt)
|
2012-10-12 |
2018-12-28 |
Medimmune Ltd |
Conjugados de pirrolobenzodiazepina-anticorpos
|
|
SMT201800346T1
(it)
|
2012-10-12 |
2018-09-13 |
Medimmune Ltd |
Coniugati pirrolobenzodiazepina-anticorpo
|
|
EP2906250B1
(en)
|
2012-10-12 |
2018-05-30 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-anti-psma antibody conjugates
|
|
ES2713164T3
(es)
|
2012-10-12 |
2019-05-20 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de las mismas
|
|
WO2014057122A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
|
|
SI2906253T1
(sl)
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-protitelo proti PSMA
|
|
US10695433B2
(en)
|
2012-10-12 |
2020-06-30 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP2906249B1
(en)
|
2012-10-12 |
2018-06-27 |
MedImmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
|
WO2014057074A1
(en)
*
|
2012-10-12 |
2014-04-17 |
Spirogen Sàrl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CN110627797A
(zh)
|
2012-12-21 |
2019-12-31 |
麦迪穆有限责任公司 |
用于治疗增殖性和自身免疫疾病的非对称吡咯并苯并二氮杂卓二聚物
|
|
JP6307519B2
(ja)
|
2012-12-21 |
2018-04-04 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
ピロロベンゾジアゼピンおよびその結合体
|
|
JP6340019B2
(ja)
|
2013-03-13 |
2018-06-06 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
ピロロベンゾジアゼピン及びそのコンジュゲート
|
|
EP2968596B1
(en)
|
2013-03-13 |
2019-03-06 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EA038512B1
(ru)
|
2013-03-15 |
2021-09-08 |
Регенерон Фармасьютикалз, Инк. |
Конъюгаты майтанзиноидов и их терапевтическое применение
|
|
CA2921412C
(en)
|
2013-08-26 |
2024-05-28 |
Regeneron Pharmaceuticals, Inc. |
Pharmaceutical compositions comprising macrolide diastereomers, methods of their synthesis and therapeutic uses
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2015052535A1
(en)
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10010624B2
(en)
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201317982D0
(en)
*
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
KR102399005B1
(ko)
|
2014-03-11 |
2022-05-17 |
리제너론 파마슈티칼스 인코포레이티드 |
항-egfrviii 항체 및 그것의 용도
|
|
US10188746B2
(en)
|
2014-09-10 |
2019-01-29 |
Medimmune Limited |
Pyrrolobenzodiazepines and conjugates thereof
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
US10780096B2
(en)
|
2014-11-25 |
2020-09-22 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
|
WO2016160615A1
(en)
|
2015-03-27 |
2016-10-06 |
Regeneron Pharmaceuticals, Inc. |
Maytansinoid derivatives, conjugates thereof, and methods of use
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
CA2987641A1
(en)
|
2015-07-06 |
2017-01-12 |
Regeneron Pharmaceuticals, Inc. |
Multispecific antigen-binding molecules and uses thereof
|
|
JP2018536682A
(ja)
|
2015-12-11 |
2018-12-13 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． |
Ｅｇｆｒ及び／またはｅｒｂｂ３遮断に耐性のある腫瘍の成長を低減または防止するための方法
|
|
MX390630B
(es)
|
2016-01-25 |
2025-03-21 |
Regeneron Pharma |
Derivados de maitansinoide, conjugados de los mismos y metodos de uso.
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
US11352446B2
(en)
|
2016-04-28 |
2022-06-07 |
Regeneron Pharmaceuticals, Inc. |
Methods of making multispecific antigen-binding molecules
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
TW201811376A
(zh)
|
2016-07-01 |
2018-04-01 |
英商葛蘭素史密斯克藍智慧財產權有限公司 |
抗體-藥物結合物及使用其之治療方法
|
|
RS63660B1
(sr)
|
2016-09-23 |
2022-11-30 |
Regeneron Pharma |
Anti-muc16 (mucin 16) antitela
|
|
MA46417A
(fr)
|
2016-09-23 |
2019-07-31 |
Regeneron Pharma |
Anticorps anti-steap2, conjugués anticorps-médicament, et molécules bispécifiques de liaison à l'antigène qui se lient à steap2 et cd3, et leurs utilisations
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
MY199937A
(en)
|
2016-11-08 |
2023-11-29 |
Regeneron Pharma |
Steroids and protein-conjugates thereof
|
|
TWI782930B
(zh)
|
2016-11-16 |
2022-11-11 |
美商再生元醫藥公司 |
抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
ES2871001T3
(es)
|
2017-02-08 |
2021-10-28 |
Adc Therapeutics Sa |
Conjugados de pirrolobenzodiazepinas y anticuerpos
|
|
WO2018192944A1
(en)
|
2017-04-18 |
2018-10-25 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
|
CA3057748A1
(en)
|
2017-04-20 |
2018-10-25 |
Adc Therapeutics Sa |
Combination therapy with an anti-axl antibody-drug conjugate
|
|
KR20200007905A
(ko)
|
2017-05-18 |
2020-01-22 |
리제너론 파마슈티칼스 인코포레이티드 |
사이클로덱스트린 단백질 약물 접합체
|
|
WO2018213082A1
(en)
|
2017-05-18 |
2018-11-22 |
Regeneron Pharmaceuticals, Inc. |
Bis-octahydrophenanthrene carboxamides and protein conjugates thereof
|
|
BR112019025888A2
(pt)
|
2017-06-07 |
2020-06-30 |
Regeneron Pharmaceuticals, Inc. |
polinucleotídeo que codifica uma proteína terapêutica multidomínio, vetor de terapia gênica, proteína terapêutica multidomínio recombinante, método de expressão, métodos para reduzir o acúmulo de glicogênio em um tecido em um paciente em necessidade, para reduzir o acúmulo de glicogênio em um tecido em um paciente em necessidade epara tratar a deficiência enzimática em um paciente em necessidade e/ou tolerar o paciente à enzima para a qual é deficiente, anticorpo anti-cd63 ou fragmento de ligação a antígeno, e, composição farmacêutica
|
|
ES2988683T3
(es)
|
2017-06-14 |
2024-11-21 |
Adc Therapeutics Sa |
Pautas posológicas para la administración de un CAF anti-CD19
|
|
SG11202000358YA
(en)
|
2017-08-18 |
2020-02-27 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
AU2018342527B2
(en)
|
2017-09-29 |
2024-06-27 |
Daiichi Sankyo Company, Limited |
Antibody-pyrrolobenzodiazepine derivative conjugate
|
|
CN111601619A
(zh)
|
2017-11-07 |
2020-08-28 |
里珍纳龙药品有限公司 |
用于抗体药物偶联物的亲水性连接体
|
|
US12070506B2
(en)
|
2018-01-08 |
2024-08-27 |
Regeneron Pharmaceuticals, Inc. |
Steroids and antibody-conjugates thereof
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
WO2019189453A1
(en)
|
2018-03-28 |
2019-10-03 |
Mitsubishi Tanabe Pharma Corporation |
DRUG CONJUGATES OF cMET MONOCLONAL BINDING AGENTS, AND USES THEREOF
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3788075A1
(en)
|
2018-04-30 |
2021-03-10 |
Regeneron Pharmaceuticals, Inc. |
Antibodies, and bispecific antigen-binding molecules that bind her2 and/or aplp2, conjugates, and uses thereof
|
|
AU2019265703A1
(en)
|
2018-05-09 |
2020-11-19 |
Regeneron Pharmaceuticals, Inc. |
Anti-MSR1 antibodies and methods of use thereof
|
|
MY206284A
(en)
|
2018-05-17 |
2024-12-06 |
Regeneron Pharma |
Anti-cd63 antibodies, conjugates, and uses thereof
|
|
CA3120528A1
(en)
|
2018-11-20 |
2020-05-28 |
Regeneron Pharmaceuticals, Inc. |
Bis-octahydrophenanthrene carboxamide derivatives and protein conjugates thereof for use as lxr agonists
|
|
SG11202106658XA
(en)
|
2018-12-21 |
2021-07-29 |
Regeneron Pharma |
Rifamycin analogs and antibody-drug conjugates thereof
|
|
CN113454097B
(zh)
|
2018-12-21 |
2024-08-30 |
里珍纳龙药品有限公司 |
微管溶素及蛋白质-微管溶素偶联物
|
|
JP2022517767A
(ja)
|
2019-01-08 |
2022-03-10 |
レゲネロン ファーマシューティカルス，インコーポレーテッド |
無痕跡型リンカー及びそのタンパク質－コンジュゲート
|
|
JP2022523360A
(ja)
|
2019-02-21 |
2022-04-22 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Ｍｅｔに結合する抗ｍｅｔ抗体および二特異性抗原結合分子を使用した眼癌の治療方法
|
|
MX2021010477A
(es)
|
2019-03-15 |
2021-10-01 |
Medimmune Ltd |
Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer.
|
|
CN114340684B
(zh)
|
2019-09-16 |
2025-09-12 |
瑞泽恩制药公司 |
用于免疫pet成像的放射性标记的met结合蛋白
|
|
US11814428B2
(en)
|
2019-09-19 |
2023-11-14 |
Regeneron Pharmaceuticals, Inc. |
Anti-PTCRA antibody-drug conjugates and uses thereof
|
|
CN115348874A
(zh)
|
2020-01-24 |
2022-11-15 |
里珍纳龙药品有限公司 |
蛋白质-抗病毒化合物偶联物
|
|
MX2022010599A
(es)
|
2020-02-28 |
2022-09-09 |
Regeneron Pharma |
Moleculas biespecificas de union al antigeno que se unen a her2, y metodos de uso de los mismos.
|
|
KR20230004651A
(ko)
|
2020-04-16 |
2023-01-06 |
리제너론 파마슈티칼스 인코포레이티드 |
딜스-알더 접합 방법
|
|
BR112022024361A2
(pt)
|
2020-06-24 |
2022-12-27 |
Regeneron Pharma |
Tubulisinas e conjugados de proteína-tubulisina
|
|
BR112023000489A2
(pt)
|
2020-07-13 |
2023-03-28 |
Regeneron Pharma |
Análogos de camptotecina conjugados a um resíduo de glutamina em uma proteína, e seu uso
|
|
US12280124B2
(en)
|
2020-09-14 |
2025-04-22 |
Regeneron Pharmaceuticals, Inc. |
Antibody-drug conjugates comprising GLP1 peptidomimetics and uses thereof
|
|
IL301702A
(en)
|
2020-10-22 |
2023-05-01 |
Regeneron Pharma |
Anti-FGFR2 antibodies and methods of using them
|
|
US20250041433A1
(en)
|
2021-07-28 |
2025-02-06 |
Regeneron Pharmaceuticals, Inc. |
Protein-antiviral compound conjugates
|
|
CN118317784A
(zh)
|
2021-09-30 |
2024-07-09 |
江苏恒瑞医药股份有限公司 |
吡咯并苯并二氮杂卓类衍生物及其偶联物、其制备方法及其应用
|
|
WO2023129518A1
(en)
|
2021-12-29 |
2023-07-06 |
Regeneron Pharmaceuticals, Inc. |
Tubulysins and protein-tubulysin conjugates
|
|
US20230287138A1
(en)
|
2022-01-12 |
2023-09-14 |
Regneron Pharmaceuticals, Inc. |
Protein-drug conjugates comprising camptothecin analogs and methods of use thereof
|
|
AU2023208050A1
(en)
|
2022-01-14 |
2024-07-04 |
Regeneron Pharmaceuticals, Inc. |
Verrucarin a derivatives and antibody drug conjugates thereof
|
|
CN119072335A
(zh)
|
2022-03-11 |
2024-12-03 |
瑞泽恩制药公司 |
包含glp1肽模拟物的抗glp1r抗体-药物缀合物及其用途
|
|
EP4548932A1
(en)
|
2022-06-30 |
2025-05-07 |
Toray Industries, Inc. |
Pharmaceutical composition for treating and/or preventing cancer
|
|
CN120239705A
(zh)
|
2022-07-21 |
2025-07-01 |
萤火虫生物股份有限公司 |
糖皮质激素受体激动剂和其缀合物
|
|
KR20250128394A
(ko)
|
2022-11-30 |
2025-08-27 |
리제너론 파마슈티칼스 인코포레이티드 |
Tlr7 작용제 및 이의 항체-약물-접합체
|
|
KR20250133813A
(ko)
|
2022-12-21 |
2025-09-08 |
리제너론 파마슈티칼스 인코포레이티드 |
Adc 접합을 위한 토포이소머라아제 i 억제제의 전구약물 및 이의 사용 방법
|
|
CN121001751A
(zh)
|
2023-02-09 |
2025-11-21 |
里珍纳龙药品有限公司 |
借助逆电子需求狄尔斯-阿尔德反应的抗体-药物缀合物
|
|
CN121039163A
(zh)
|
2023-05-02 |
2025-11-28 |
瑞泽恩制药公司 |
抗人m-钙粘蛋白（cdh15）抗体、缀合物及其用于将遗传有效负载递送至肌肉细胞的用途
|
|
WO2025014533A1
(en)
|
2023-07-10 |
2025-01-16 |
Regeneron Pharmaceuticals, Inc. |
Anti-human cacng1 antibody-drug conjugates and uses thereof
|
|
US20250171516A1
(en)
|
2023-11-03 |
2025-05-29 |
Regeneron Pharmaceuticals, Inc. |
Peptide acids as a glp1r agonist and antibody-drug conjugates thereof
|
|
WO2025117727A1
(en)
|
2023-11-29 |
2025-06-05 |
Regeneron Pharmaceuticals, Inc. |
Analogs of quinoxaline/quinoline cytotoxins, linker- payloads, protein-drug conjugates, and uses thereof
|