|
DE102008063992A1
(de)
*
|
2008-12-19 |
2010-09-02 |
Lerner, Zinoviy, Dipl.-Ing. |
Neue aliphatisch substituierte Pyrazolopyridine und ihre Verwendung
|
|
PL2604608T3
(pl)
|
2009-11-27 |
2016-02-29 |
Adverio Pharma Gmbh |
Sposób wytwarzania {4,6-diamino-2-[1-(2-fluorobenzylo)-1H-pirazolo[3,4-b]pirydyn-3-ylo]pirymidyn-5-ylo}metylokarbaminianu metylu
|
|
US9284301B2
(en)
|
2010-03-25 |
2016-03-15 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase activators
|
|
DE102010021637A1
(de)
*
|
2010-05-26 |
2011-12-01 |
Bayer Schering Pharma Aktiengesellschaft |
Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung
|
|
KR20140019004A
(ko)
|
2010-05-27 |
2014-02-13 |
머크 샤프 앤드 돔 코포레이션 |
가용성 구아닐레이트 시클라제 활성화제
|
|
EA201390060A1
(ru)
|
2010-07-09 |
2013-07-30 |
Байер Интеллектуэль Проперти Гмбх |
Аннелированные пиримидины и триазины и их применение для лечения и/или профилактики сердечно-сосудистых заболеваний
|
|
EP2632551B1
(en)
|
2010-10-28 |
2016-07-06 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase activators
|
|
DE102010043379A1
(de)
|
2010-11-04 |
2012-05-10 |
Bayer Schering Pharma Aktiengesellschaft |
Substituierte 6-Fluor-1H-Pyrazolo[4,3-b]pyridine und ihre Verwendung
|
|
DE102010043380A1
(de)
|
2010-11-04 |
2012-05-10 |
Bayer Schering Pharma Aktiengesellschaft |
Benzyl-substituierte Carbamate und ihre Verwendung
|
|
DE102011007272A1
(de)
|
2011-04-13 |
2012-10-18 |
Bayer Pharma Aktiengesellschaft |
Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung
|
|
JP6005134B2
(ja)
|
2011-04-21 |
2016-10-12 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ |
フルオロアルキル置換ピラゾロピリジンおよびその使用
|
|
EP2594270A3
(en)
*
|
2011-11-18 |
2013-07-31 |
BIP Patents |
The use of sGC stimulators, sGC activators, alone and combinations with PDE5 inhibitors for the treatment of systemic sclerosis (SSc)
|
|
ES2603028T3
(es)
*
|
2011-11-25 |
2017-02-23 |
Adverio Pharma Gmbh |
Procedimiento para la preparación de (Z)-alfa-fluoro-beta-amino-acrilaldehídos sustituidos
|
|
CN102491974B
(zh)
|
2011-12-12 |
2013-08-07 |
南京药石药物研发有限公司 |
1-（2-氟苄基）-1H-吡唑并[3，4-b]吡啶-3-甲脒盐酸盐的合成方法
|
|
DE102012200360A1
(de)
|
2012-01-11 |
2013-07-11 |
Bayer Intellectual Property Gmbh |
Substituierte Triazine und ihre Verwendung
|
|
DE102012200349A1
(de)
*
|
2012-01-11 |
2013-07-11 |
Bayer Intellectual Property Gmbh |
Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
|
|
DE102012200352A1
(de)
*
|
2012-01-11 |
2013-07-11 |
Bayer Intellectual Property Gmbh |
Substituierte, annellierte Imidazole und Pyrazole und ihre Verwendung
|
|
WO2013131923A1
(de)
|
2012-03-06 |
2013-09-12 |
Bayer Intellectual Property Gmbh |
Substituierte azabicyclen und ihre verwendung
|
|
WO2013144191A1
(de)
|
2012-03-29 |
2013-10-03 |
Bayer Intellectual Property Gmbh |
Substituierte 2 -amino - 3 - cyanopyridine als inhibitoren des natrium calcium austausches und ihre verwendung bei kardiovaskulären erkrankungen
|
|
RS55651B1
(sr)
|
2012-07-20 |
2017-06-30 |
Bayer Pharma AG |
Nove 5-aminotetrahidrohinolin-2-karbonske kiseline i njihova upotreba
|
|
CA2879456A1
(en)
|
2012-07-20 |
2014-01-23 |
Bayer Pharma Aktiengesellschaft |
Substituted aminoindane- and aminotetralincarboxylic acids and use thereof
|
|
EA027909B1
(ru)
|
2012-11-30 |
2017-09-29 |
Астеллас Фарма Инк. |
Имидазопиридиновые соединения
|
|
MX2015010725A
(es)
|
2013-02-21 |
2016-05-31 |
Adverio Pharma Gmbh |
Formas de metil {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo [3,4-b] piridino-3-il] pirimidino-5-il} metil carbamato.
|
|
MX2015010966A
(es)
|
2013-03-01 |
2016-04-04 |
Bayer Pharma AG |
Pirimidinas fusionadas sustituidas con trifluorometilo y sus usos.
|
|
JP2016522231A
(ja)
|
2013-06-21 |
2016-07-28 |
バイエル ファーマ アクチエンゲゼルシャフト |
ジアミノヘテロアリール置換ピラゾール類
|
|
AP2016008970A0
(en)
|
2013-07-10 |
2016-01-31 |
Bayer Pharma AG |
Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof
|
|
EP3024455A1
(en)
|
2013-07-25 |
2016-06-01 |
Bayer Pharma Aktiengesellschaft |
Sgc stimulators or sgc activators and pde5 inhibitors in combination with additional treatment for the therapy of cystic fibrosis
|
|
TW201605812A
(zh)
|
2013-09-16 |
2016-02-16 |
拜耳製藥股份有限公司 |
經雙取代之三氟甲基嘧啶酮類及其用途
|
|
KR20160065957A
(ko)
|
2013-10-07 |
2016-06-09 |
바이엘 파마 악티엔게젤샤프트 |
시클릭 티에노우라실-카르복스아미드 및 그의 용도
|
|
WO2015088886A1
(en)
|
2013-12-11 |
2015-06-18 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase activators
|
|
WO2015088885A1
(en)
|
2013-12-11 |
2015-06-18 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase activators
|
|
EP3094327A1
(en)
|
2014-01-13 |
2016-11-23 |
Ironwood Pharmaceuticals, Inc. |
USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
|
|
US20170119776A1
(en)
|
2014-04-03 |
2017-05-04 |
Bayer Pharma Aktiengesellschaft |
Chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives and use thereof
|
|
CA2944614A1
(en)
|
2014-04-03 |
2015-10-08 |
Bayer Pharma Aktiengesellschaft |
2,5-disubstituted cyclopentane carboxylic acids for the treatment of respiratoy tract diseases
|
|
US20170022171A1
(en)
|
2014-04-03 |
2017-01-26 |
Bayer Pharma Aktiengesellschaft |
2,5-disubstituted cyclopentanecarboxylic acids and their use
|
|
US9796733B2
(en)
|
2014-06-04 |
2017-10-24 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators
|
|
EP3191452A1
(de)
|
2014-09-09 |
2017-07-19 |
Bayer Pharma Aktiengesellschaft |
Substituierte n,2-diarylchinolin-4-carboxamide und ihre anti-inflammatorische verwendung
|
|
EP3197891B1
(de)
|
2014-09-24 |
2018-11-21 |
Bayer Pharma Aktiengesellschaft |
Faktor xia hemmende pyridobenzazepin- und pyridobenzazocin-derivate
|
|
SI3215498T1
(sl)
|
2014-11-03 |
2018-11-30 |
Bayer Pharma Aktiengesellschaft |
Hidroksialkil-substituirani derivati feniltriazola in njihove uporabe
|
|
TW201625635A
(zh)
|
2014-11-21 |
2016-07-16 |
默沙東藥廠 |
作為可溶性鳥苷酸環化酶活化劑之三唑并吡基衍生物
|
|
WO2016113205A1
(de)
|
2015-01-13 |
2016-07-21 |
Bayer Pharma Aktiengesellschaft |
Substituierte pentafluorethylpyrimidinone und ihre verwendung
|
|
UY36586A
(es)
|
2015-03-26 |
2016-10-31 |
Bayer Pharma AG |
Heterociclilmetiltienouracilos y uso de los mismos
|
|
MX2017014057A
(es)
|
2015-05-06 |
2018-04-10 |
Bayer Pharma AG |
El uso de estimuladores sgc, activadores gc, solos y combinaciones con inhibidores pde5 para el tratamiento de ulceras digitales (du) concomitante con esclerosis sistemica (ssc).
|
|
WO2016191334A1
(en)
|
2015-05-27 |
2016-12-01 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
|
WO2016191335A1
(en)
|
2015-05-28 |
2016-12-01 |
Merck Sharp & Dohme Corp. |
Imidazo-pyrazinyl derivatives useful as soluble guanylate cyclase activators
|
|
JP6849618B2
(ja)
*
|
2015-07-23 |
2021-03-24 |
バイエル・ファルマ・アクティエンゲゼルシャフト |
中性エンドペプチダーゼの阻害剤（ＮＥＰ阻害剤）および／またはアンジオテンシンＩＩ拮抗薬と組み合わせた可溶性グアニル酸シクラーゼ（ｓＧＣ）の刺激薬および／または活性化薬ならびにその使用
|
|
WO2017097671A1
(de)
|
2015-12-10 |
2017-06-15 |
Bayer Pharma Aktiengesellschaft |
Substituierte perhydropyrrolo[3,4-c]pyrrol-derivate und ihre verwendung
|
|
JP2018536693A
(ja)
|
2015-12-10 |
2018-12-13 |
バイエル・ファルマ・アクティエンゲゼルシャフト |
睡眠関連呼吸障害を治療するためのＴＡＳＫ−１およびＴＡＳＫ−２チャネルの遮断薬としての２−フェニル−３−（ピペラジノメチル）イミダゾ［１，２−ａ］ピリジン誘導体
|
|
US20180344735A1
(en)
|
2015-12-14 |
2018-12-06 |
Ironwood Pharmaceuticals, Inc. |
USE OF sGC STIMULATORS FOR THE TREATMENT OF GASTROINTESTINAL SPHINCTER DYSFUNCTION
|
|
CN105461715B
(zh)
*
|
2015-12-15 |
2017-03-29 |
郑州大明药物科技有限公司 |
一种利奥西呱中间体的合成方法
|
|
WO2017107052A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase stimulators
|
|
WO2017121692A1
(de)
|
2016-01-15 |
2017-07-20 |
Bayer Pharma Aktiengesellschaft |
Substituierte sulfamide und ihre verwendung
|
|
AU2017216429B2
(en)
*
|
2016-02-01 |
2022-10-06 |
Cyclerion Therapeutics, Inc. |
Use of sGC stimulators for the treatment of Nonalcoholic Steatohepatitis (NASH)
|
|
WO2017153235A1
(de)
|
2016-03-09 |
2017-09-14 |
Bayer Pharma Aktiengesellschaft |
Substituierte n-cyclo-3-aryl-1-naphthamide und ihre verwendung
|
|
WO2017153234A1
(de)
|
2016-03-09 |
2017-09-14 |
Bayer Pharma Aktiengesellschaft |
Substituierte n-cyclo-2-arylchinolin-4-carboxamide und ihre verwendung
|
|
WO2017153231A1
(de)
|
2016-03-09 |
2017-09-14 |
Bayer Pharma Aktiengesellschaft |
Substituierte n-cyclo-2-arylisochinolinon-4-carboxamide und ihre verwendung
|
|
WO2017191115A1
(en)
|
2016-05-03 |
2017-11-09 |
Bayer Pharma Aktiengesellschaft |
Oxoalkyl-substituted phenyltriazole derivatives and uses thereof
|
|
US9988367B2
(en)
|
2016-05-03 |
2018-06-05 |
Bayer Pharma Aktiengesellschaft |
Amide-substituted pyridinyltriazole derivatives and uses thereof
|
|
WO2017191117A1
(en)
|
2016-05-03 |
2017-11-09 |
Bayer Pharma Aktiengesellschaft |
V1a receptor antagonists for use in the treatment of renal diseases
|
|
EP3452472A1
(en)
|
2016-05-03 |
2019-03-13 |
Bayer Aktiengesellschaft |
Hydroxyalkyl-substituted heteroaryltriazole derivatives and uses thereof
|
|
US20190119251A1
(en)
|
2016-05-03 |
2019-04-25 |
Bayer Pharma Aktiengesellschaft |
Amide-substituted aryltriazole derivatives and uses thereof
|
|
AR108263A1
(es)
|
2016-05-03 |
2018-08-01 |
Bayer Pharma AG |
Procedimiento para la preparación de derivados de 1-fenilo-1,2,4-triazol sustituidos por 5-hidroxialquilo
|
|
EP3452469A1
(en)
|
2016-05-03 |
2019-03-13 |
Bayer Pharma Aktiengesellschaft |
Fluoroalkyl-substituted aryltriazole derivatives and uses thereof
|
|
JOP20170113B1
(ar)
|
2016-05-09 |
2023-03-28 |
Bayer Pharma AG |
مركبات 5، 6، 7، 8-رباعي هيدرو [1، 2، 4] تريازولو [4، 3-أ] بيريدين 3(2h)-ون مستبدلة ومركبات 2، 5، 6، 7-رباعي هيدرو-3h-بيرولو [2، 1-ج] [1، 2، 4] تريازول-3-ون واستخداماتها
|
|
WO2017197555A1
(en)
|
2016-05-16 |
2017-11-23 |
Merck Sharp & Dohme Corp. |
Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators
|
|
EP3458063A4
(en)
|
2016-05-18 |
2020-02-26 |
Merck Sharp & Dohme Corp. |
METHOD FOR USE OF TRIAZOLO-PYRAZINYL-SOLUBLE GUANYLATE CYCLASE ACTIVATORS IN FIBROTIC DISEASES
|
|
CN109689654A
(zh)
|
2016-07-11 |
2019-04-26 |
拜耳医药股份有限公司 |
7-取代的1-吡啶基-萘啶-3-甲酰胺类及其用途
|
|
JOP20190005A1
(ar)
|
2016-07-20 |
2019-01-20 |
Bayer Ag |
مركبات ديازاهيترو ثنائية الحلقة مستبدلة واستخداماتها
|
|
WO2018041771A1
(de)
|
2016-09-02 |
2018-03-08 |
Bayer Pharma Aktiengesellschaft |
(1-methylcyclopropyl)methyl-substituierte thienouracile und ihre verwendung
|
|
JOP20190045A1
(ar)
|
2016-09-14 |
2019-03-14 |
Bayer Ag |
مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.
|
|
EP3296298A1
(de)
|
2016-09-14 |
2018-03-21 |
Bayer Pharma Aktiengesellschaft |
7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung
|
|
CA3037642A1
(en)
|
2016-09-23 |
2018-03-29 |
Bayer Aktiengesellschaft |
N 3 -cyclically substituted thienouraciles and use thereof
|
|
EP3525779B1
(de)
*
|
2016-10-11 |
2024-06-05 |
Bayer Pharma Aktiengesellschaft |
Kombination enthaltend den sgc stimulator vericuguat und den mineralcorticoid-rezeptor-antagonist finerenone
|
|
CN109890379A
(zh)
|
2016-10-11 |
2019-06-14 |
拜耳制药股份公司 |
包含sGC活化剂和盐皮质激素受体拮抗剂的组合产品
|
|
JOP20190080A1
(ar)
|
2016-10-14 |
2019-04-11 |
Bayer Pharma AG |
مركبات مشتقة من 6-(1h-بيرازول-1-يل) بيريميدين-4- أمين مستبدل واستخداماتها
|
|
WO2018073144A1
(en)
|
2016-10-20 |
2018-04-26 |
Bayer Pharma Aktiengesellschaft |
Hydroxyalkyl-substituted triazole derivatives and uses thereof
|
|
EP3554488A2
(en)
|
2016-12-13 |
2019-10-23 |
Cyclerion Therapeutics, Inc. |
Use of sgc stimulators for the treatment of esophageal motility disorders
|
|
EP3338764A1
(de)
|
2016-12-21 |
2018-06-27 |
Bayer Pharma Aktiengesellschaft |
Pharmazeutische darreichungsformen enthaltend inhibitoren von task-1 und task-3 kanälen und deren verwendung für die therapie von atemstörungen
|
|
EP3338803A1
(de)
|
2016-12-21 |
2018-06-27 |
Bayer Pharma Aktiengesellschaft |
Pharmazeutische darreichungsformen enthaltend inhibitoren von task-1 und task-3 kanälen und deren verwendung für die therapie von atemstörungen
|
|
JOP20190148A1
(ar)
|
2016-12-21 |
2019-06-18 |
Bayer Pharma AG |
أشكال جرعات صيدلية تحتوي على مثبطات قنوات task-1 و task-3 واستخدامها لمعالجة الاضطرابات التنفسية
|
|
JOP20190141A1
(ar)
|
2016-12-21 |
2019-06-12 |
Bayer Pharma AG |
أشكال جرعات صيدلية تحتوي على مثبطات لقناة task-1 و task-3 واستخدامها في معالجة اضطراب تنفسي
|
|
WO2018153899A1
(de)
*
|
2017-02-22 |
2018-08-30 |
Bayer Pharma Aktiengesellschaft |
Selektive partielle adenosin a1 rezeptor-agonisten in kombination mit stimulatoren und/oder aktivatoren der löslichen guanylatcyclase (sgc)
|
|
TWI770157B
(zh)
|
2017-04-10 |
2022-07-11 |
德商拜耳廠股份有限公司 |
經取代之n-芳基乙基-2-胺基喹啉-4-甲醯胺及其用途
|
|
US11136296B2
(en)
|
2017-04-10 |
2021-10-05 |
Bayer Aktiengesellschaft |
Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof
|
|
ES2924359T3
(es)
|
2017-04-11 |
2022-10-06 |
Sunshine Lake Pharma Co Ltd |
Compuestos de indazol sustituidos con flúor y usos de los mismos
|
|
CN108690016B
(zh)
*
|
2017-04-11 |
2022-08-12 |
广东东阳光药业有限公司 |
吡唑并吡啶类化合物及其用途
|
|
JOP20190284A1
(ar)
|
2017-06-14 |
2019-12-11 |
Bayer Pharma AG |
مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس
|
|
WO2018227427A1
(en)
|
2017-06-14 |
2018-12-20 |
Bayer Aktiengesellschaft |
Substituted bridged diazepane derivatives and use thereof
|
|
WO2019081353A1
(de)
*
|
2017-10-24 |
2019-05-02 |
Bayer Aktiengesellschaft |
Substituierte imidazopyridinamide und ihre verwendung
|
|
WO2019081291A1
(en)
|
2017-10-24 |
2019-05-02 |
Bayer Aktiengesellschaft |
PRODRUGS OF SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
|
|
WO2019081303A1
(en)
|
2017-10-24 |
2019-05-02 |
Bayer Pharma Aktiengesellschaft |
SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
|
|
EP3700896A1
(en)
|
2017-10-24 |
2020-09-02 |
Bayer Pharma Aktiengesellschaft |
Amine substituted triazole derivatives and uses thereof
|
|
US20210253557A1
(en)
|
2017-10-24 |
2021-08-19 |
Bayer Pharma Aktiengesellschaft |
Substituted triazole derivatives and uses thereof
|
|
EP3700900A1
(en)
|
2017-10-24 |
2020-09-02 |
Bayer Aktiengesellschaft |
Substituted triazole derivatives and uses thereof
|
|
PT3700913T
(pt)
|
2017-10-24 |
2022-01-31 |
Bayer Pharma AG |
Profármacos de derivados de triazol substituído e utilizações dos mesmos
|
|
WO2019081306A1
(en)
|
2017-10-24 |
2019-05-02 |
Bayer Pharma Aktiengesellschaft |
SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
|
|
WO2019091847A1
(de)
|
2017-11-07 |
2019-05-16 |
Bayer Aktiengesellschaft |
Substituierte 2,4-dihydro-3h-1,2,4-triazol-3-one und ihre verwendung
|
|
SG11202004577VA
(en)
|
2017-12-01 |
2020-06-29 |
Bayer Pharma AG |
Method for producing (3s)-3-(4-chlor-3-{[(2s,3r)-2-(4-chlorphenyl)-4,4,4-trifluor-3-methylbutanoyl]amino}phenyl)-3-cyclo-propylpropanoic acid and the crystalline form thereof for use as a pharmaceutical ingredient
|
|
MX2020006433A
(es)
*
|
2017-12-19 |
2020-09-17 |
Cyclerion Therapeutics Inc |
Estimuladores de guanilato ciclasa soluble (sgc).
|
|
EP3553081A1
(en)
|
2018-04-12 |
2019-10-16 |
Bayer Aktiengesellschaft |
Atrial natriuretic peptide engrafted antibodies
|
|
EP3553082A1
(en)
|
2018-04-12 |
2019-10-16 |
Bayer Aktiengesellschaft |
Brain natriuretic peptide engrafted antibodies
|
|
EP3553079A1
(en)
|
2018-04-12 |
2019-10-16 |
Bayer Aktiengesellschaft |
C-type natriuretic peptide engrafted antibodies
|
|
EP3787610A1
(en)
*
|
2018-04-30 |
2021-03-10 |
Bayer Aktiengesellschaft |
The use of sgc activators and sgc stimulators for the treatment of cognitive impairment
|
|
EP3566704A1
(en)
|
2018-05-11 |
2019-11-13 |
Bayer Aktiengesellschaft |
The use of non-steroidal mineralocorticoid receptor antagonists alone or in combination for the treatment of muscular or neuromuscular diseases
|
|
EP3793553A1
(en)
|
2018-05-15 |
2021-03-24 |
Bayer Aktiengesellschaft |
1,3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization
|
|
EP3793559A1
(en)
|
2018-05-17 |
2021-03-24 |
Bayer Aktiengesellschaft |
Substituted dihydropyrazolo pyrazine carboxamide derivatives
|
|
EP3574905A1
(en)
|
2018-05-30 |
2019-12-04 |
Adverio Pharma GmbH |
Method of identifying a subgroup of patients suffering from dcssc which benefits from a treatment with sgc stimulators and sgc activators in a higher degree than a control group
|
|
KR20250141845A
(ko)
|
2018-07-11 |
2025-09-29 |
티센토 쎄라퓨틱스 인크. |
미토콘드리아 장애의 치료를 위한 sGC 자극제의 용도
|
|
CN112469398A
(zh)
|
2018-07-24 |
2021-03-09 |
拜耳公司 |
可口服给药并具有缓释作用的药物剂型
|
|
UY38308A
(es)
|
2018-07-24 |
2020-02-28 |
Bayer Pharma AG |
Forma de dosificación farmacéutica administrable por vía oral con liberación modificada
|
|
US10905667B2
(en)
|
2018-07-24 |
2021-02-02 |
Bayer Pharma Aktiengesellschaft |
Orally administrable modified-release pharmaceutical dosage form
|
|
PE20211285A1
(es)
|
2018-11-27 |
2021-07-19 |
Bayer Ag |
Proceso para la produccion de formas farmaceuticas que contienen inhibidores de los canales task-1 y task-3 y su uso para la terapia de trastornos respiratorios
|
|
TWI830835B
(zh)
|
2018-12-17 |
2024-02-01 |
德商亞德維瑞醫藥有限公司 |
具改善性質之{4,6-二胺基-2-[5-氟-1-(2-氟芐基)-1H-吡唑並[3,4-b]吡啶-3-基]嘧啶-5-基}胺基甲酸甲酯活性化合物產物、其製造及調配物
|
|
WO2020164008A1
(en)
|
2019-02-13 |
2020-08-20 |
Bayer Aktiengesellschaft |
Process for the preparation of porous microparticles
|
|
WO2020216669A1
(de)
|
2019-04-23 |
2020-10-29 |
Bayer Aktiengesellschaft |
Phenylsubstituierte imidazopyridinamide und ihre verwendung
|
|
MX2021013616A
(es)
|
2019-05-07 |
2021-12-10 |
Bayer Ag |
Compuestos inhibidores de la masp y usos de estos.
|
|
WO2020245342A1
(en)
|
2019-06-07 |
2020-12-10 |
Bayer Aktiengesellschaft |
The use of sgc activators for the treatment of ophthalmologic diseases
|
|
PE20221025A1
(es)
|
2019-11-06 |
2022-06-16 |
Bayer Ag |
Inhibidores de los receptores a2c adrenergicos
|
|
WO2021094208A1
(en)
|
2019-11-12 |
2021-05-20 |
Bayer Aktiengesellschaft |
Substituted imidazo pyrimidine ep3 antagonists
|
|
WO2021094210A1
(en)
|
2019-11-12 |
2021-05-20 |
Bayer Aktiengesellschaft |
Substituted pyrazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
|
|
WO2021094209A1
(en)
|
2019-11-12 |
2021-05-20 |
Bayer Aktiengesellschaft |
Substituted pyrrolo triazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
|
|
EP3822268A1
(en)
|
2019-11-15 |
2021-05-19 |
Bayer Aktiengesellschaft |
Substituted hydantoinamides as adamts7 antagonists
|
|
EP3822265A1
(en)
|
2019-11-15 |
2021-05-19 |
Bayer AG |
Substituted hydantoinamides as adamts7 antagonists
|
|
EP4099987B1
(en)
*
|
2020-02-03 |
2025-03-12 |
Adverio Pharma GmbH |
Nanoformulations of methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate
|
|
CA3170507A1
(en)
|
2020-02-21 |
2021-08-26 |
Universiteit Maastricht |
Use of a soluble guanylate cyclase (sgc) stimulator or of a combination of a sgc stimulator and an sgc activator for conditions wherein the heme group of sgc is oxidized or wherein sgc is deficient in heme
|
|
US20230083417A1
(en)
|
2020-02-26 |
2023-03-16 |
Universiteit Maastricht |
Therapeutic combination for the treatment of brain ischemia and said therapeutic combination for use in the treatment of brain ischemia
|
|
US20230130739A1
(en)
|
2020-03-26 |
2023-04-27 |
Cyclerion Therapeutics, Inc. |
DEUTERATED sGC STIMULATORS
|
|
EP3925953A1
(en)
|
2020-06-16 |
2021-12-22 |
Adverio Pharma GmbH |
Process for preparing methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate
|
|
EP4011904A1
(en)
|
2020-12-14 |
2022-06-15 |
Bayer Aktiengesellschaft |
Masp inhibitory compounds and uses thereof
|
|
WO2022096394A1
(en)
|
2020-11-04 |
2022-05-12 |
Bayer Aktiengesellschaft |
Masp inhibitory compounds and uses thereof
|
|
WO2022112213A1
(en)
|
2020-11-30 |
2022-06-02 |
Bayer Aktiengesellschaft |
Crystalline forms of 3-[[3-(4-chlorophenyl)-5-oxo-4-((2s)-3,3,3-trifluoro- 2-hydroxypropyl)-4,5-dihydro-1h-1,2,4-triazol-1-yl]methyl]-1-[3- (trifluoromethyl)pyridin-2-yl]-1h-1,2,4-triazole-5-carboxamide
|
|
AR124297A1
(es)
|
2020-12-10 |
2023-03-15 |
Bayer Ag |
Ácidos pirazol piperidin carboxílicos sustituidos
|
|
EP4011873A1
(en)
|
2020-12-10 |
2022-06-15 |
Bayer Aktiengesellschaft |
Substituted pyrazolo piperidine carboxylic acids
|
|
CN116829545A
(zh)
|
2020-12-10 |
2023-09-29 |
拜耳公司 |
取代的吡唑基哌啶羧酸
|
|
EP4011874A1
(en)
|
2020-12-10 |
2022-06-15 |
Bayer Aktiengesellschaft |
Substituted pyrazolo piperidine carboxylic acids
|
|
AU2021398486A1
(en)
|
2020-12-10 |
2023-06-22 |
Bayer Aktiengesellschaft |
The use of sgc activators for the treatment of ophthalmologic diseases
|
|
US20240208979A1
(en)
|
2021-04-20 |
2024-06-27 |
Tisento Therapeutics Inc. |
sGC STIMULATORS
|
|
EP4326268A1
(en)
|
2021-04-20 |
2024-02-28 |
Tisento Therapeutics Inc. |
Treatment of cns diseases with sgc stimulators
|
|
WO2023034364A1
(en)
|
2021-08-31 |
2023-03-09 |
Teva Pharmaceuticals International Gmbh |
Solid state forms of vericiguat and process for preparation thereof
|
|
KR20240144177A
(ko)
|
2021-12-29 |
2024-10-02 |
바이엘 악티엔게젤샤프트 |
(5s)-{[2-(4-카르복시페닐)에틸][2-(2-{[3-클로로-4'-(트리플루오로메틸)비페닐-4-일]메톡시}페닐)에틸]아미노}-5,6,7,8-테트라히드로퀴놀린-2-카르복실산및 약학적 활성 화합물로서 사용하기 위한 이의 결정질 형태를 제조하는 방법
|
|
EP4456896A1
(en)
|
2021-12-29 |
2024-11-06 |
Bayer Aktiengesellschaft |
Treatment of cardiopulmonary disorders
|
|
AU2022427770A1
(en)
|
2021-12-29 |
2024-07-04 |
Bayer Aktiengesellschaft |
Pharmaceutical dry powder inhalation formulation
|
|
ES2956054B2
(es)
|
2022-05-03 |
2024-07-01 |
Moehs Iberica Sl |
2-(5-FLUORO-1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL)-5-NITROSOPIRIMIDIN-4,6-DIAMINA O UNA SAL DE LA MISMA, PROCEDIMIENTO PARA SU PREPARACION Y SU USO EN LA SINTESIS DE VERICIGUAT
|
|
EP4536205A1
(en)
|
2022-06-09 |
2025-04-16 |
Bayer Aktiengesellschaft |
Soluble guanylate cyclase activators for use in the treatment of heart failure with preserved ejection fraction in women
|
|
EP4605080A1
(en)
|
2022-10-18 |
2025-08-27 |
Tisento Therapeutics Inc. |
Treatment of mitochondrial diseases with sgc stimulators
|
|
EP4605394A1
(en)
|
2022-10-18 |
2025-08-27 |
Tisento Therapeutics Inc. |
Pyrimidine sgc stimulators
|
|
CN116239609A
(zh)
*
|
2022-12-06 |
2023-06-09 |
山东百诺医药股份有限公司 |
一种维立西呱的关键杂质及其制备方法
|
|
WO2025068514A1
(en)
|
2023-09-28 |
2025-04-03 |
Bayer Aktiengesellschaft |
Substituted heterocyclic carboxamindes and use thereof
|
|
WO2025114276A1
(en)
|
2023-12-01 |
2025-06-05 |
Krka, D.D., Novo Mesto |
Solid oral composition comprising vericiguat
|
|
US20250205235A1
(en)
|
2023-12-20 |
2025-06-26 |
Adverio Pharma Gmbh |
Dose regimen for vericiguat
|
|
CN117924280B
(zh)
*
|
2024-03-20 |
2024-07-12 |
中国人民解放军军事科学院军事医学研究院 |
取代噻吩基-5-氟-1h-吡唑并吡啶类化合物及其用途
|
|
WO2026057833A1
(en)
|
2024-09-16 |
2026-03-19 |
Adverio Pharma Gmbh |
Treatment of chronic heart failure with vericiguat
|
|
CN121735952A
(zh)
*
|
2026-02-26 |
2026-03-27 |
山东齐都药业有限公司 |
维立西呱的制备方法及其中间产物
|