JOP20190045A1 - مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. - Google Patents
مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.Info
- Publication number
- JOP20190045A1 JOP20190045A1 JOP/2019/0045A JOP20190045A JOP20190045A1 JO P20190045 A1 JOP20190045 A1 JO P20190045A1 JO P20190045 A JOP20190045 A JO P20190045A JO P20190045 A1 JOP20190045 A1 JO P20190045A1
- Authority
- JO
- Jordan
- Prior art keywords
- substituted
- naphthyridine
- aryl
- carboxylic acid
- acid amides
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Abstract
يتعلق الاختراع الحالي بمركبات 1-aryl-naphthyridine-3-carboxylic acid amides مستبدلة في الموضع 7، وبطريقة لإنتاجها، وباستخدامها سواء لوحدها أو في توليفة في المعالجة و/أو الوقاية من أمراض واستخدامها لإنتاج أدوية للمعالجة و/أو الوقاية من أمراض، وبصورة خاصة للمعالجة و/أو الوقاية من الأمراض القلبية الوعائية وأمراض الكلى.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16188728.6A EP3296298A1 (de) | 2016-09-14 | 2016-09-14 | 7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung |
EP16202509 | 2016-12-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
JOP20190045A1 true JOP20190045A1 (ar) | 2019-03-14 |
Family
ID=59966701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2019/0045A JOP20190045A1 (ar) | 2016-09-14 | 2017-06-16 | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
Country Status (40)
Families Citing this family (4)
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KR20180016485A (ko) | 2015-06-09 | 2018-02-14 | 바이엘 파마 악티엔게젤샤프트 | 무스카린성 m2 수용체의 양성 알로스테릭 조정제 |
CA3030204A1 (en) | 2016-07-11 | 2018-01-18 | Bayer Pharma Aktiengesellschaft | 7-substituted 1-pyridyl-naphthyridine-3-carboxylic acid amides and use thereof |
JOP20190045A1 (ar) | 2016-09-14 | 2019-03-14 | Bayer Ag | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
CA3179525A1 (en) * | 2020-04-08 | 2021-10-14 | Bayer Aktiengesellschaft | Rapid detection of viral infection using rt-pcr |
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CA3030204A1 (en) | 2016-07-11 | 2018-01-18 | Bayer Pharma Aktiengesellschaft | 7-substituted 1-pyridyl-naphthyridine-3-carboxylic acid amides and use thereof |
JOP20190045A1 (ar) * | 2016-09-14 | 2019-03-14 | Bayer Ag | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
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2017
- 2017-06-16 JO JOP/2019/0045A patent/JOP20190045A1/ar unknown
- 2017-09-06 CR CR20190131A patent/CR20190131A/es unknown
- 2017-09-06 RS RS20211093A patent/RS62299B1/sr unknown
- 2017-09-06 KR KR1020197007039A patent/KR20190046851A/ko active IP Right Grant
- 2017-09-06 SI SI201730869T patent/SI3512849T1/sl unknown
- 2017-09-06 NZ NZ751297A patent/NZ751297A/en unknown
- 2017-09-06 CN CN202211273001.4A patent/CN115477649A/zh active Pending
- 2017-09-06 BR BR112019004982A patent/BR112019004982A2/pt active Search and Examination
- 2017-09-06 US US16/333,079 patent/US10927109B2/en active Active
- 2017-09-06 MA MA46235A patent/MA46235B1/fr unknown
- 2017-09-06 MX MX2019003007A patent/MX2019003007A/es unknown
- 2017-09-06 CN CN201780056605.4A patent/CN109689656B/zh active Active
- 2017-09-06 SG SG11201901973RA patent/SG11201901973RA/en unknown
- 2017-09-06 JP JP2019535448A patent/JP7295019B2/ja active Active
- 2017-09-06 LT LTEPPCT/EP2017/072339T patent/LT3512849T/lt unknown
- 2017-09-06 UA UAA201903730A patent/UA125627C2/uk unknown
- 2017-09-06 CA CA3036497A patent/CA3036497A1/en active Pending
- 2017-09-06 PE PE2019000524A patent/PE20190803A1/es unknown
- 2017-09-06 HU HUE17772322A patent/HUE056343T2/hu unknown
- 2017-09-06 WO PCT/EP2017/072339 patent/WO2018050510A1/de unknown
- 2017-09-06 CU CU2019000020A patent/CU24618B1/es unknown
- 2017-09-06 MY MYPI2019001243A patent/MY196473A/en unknown
- 2017-09-06 KR KR1020237006804A patent/KR20230035437A/ko active IP Right Grant
- 2017-09-06 TN TNP/2019/000083A patent/TN2019000083A1/en unknown
- 2017-09-06 CN CN202211273380.7A patent/CN115429798A/zh active Pending
- 2017-09-06 ES ES17772322T patent/ES2887674T3/es active Active
- 2017-09-06 DK DK17772322.8T patent/DK3512849T3/da active
- 2017-09-06 EP EP17772322.8A patent/EP3512849B1/de active Active
- 2017-09-06 CN CN202211273015.6A patent/CN115554294A/zh active Pending
- 2017-09-06 AU AU2017326297A patent/AU2017326297B2/en not_active Ceased
- 2017-09-06 PL PL17772322T patent/PL3512849T3/pl unknown
- 2017-09-06 GE GEAP201715045A patent/GEP20217332B/en unknown
- 2017-09-14 UY UY0001037403A patent/UY37403A/es unknown
- 2017-09-14 TW TW106131572A patent/TWI758325B/zh active
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2019
- 2019-02-28 IL IL265106A patent/IL265106B/en unknown
- 2019-03-12 PH PH12019500535A patent/PH12019500535A1/en unknown
- 2019-03-14 CL CL2019000670A patent/CL2019000670A1/es unknown
- 2019-03-14 EC ECSENADI201918116A patent/ECSP19018116A/es unknown
- 2019-03-14 CO CONC2019/0002361A patent/CO2019002361A2/es unknown
- 2019-03-14 DO DO2019000060A patent/DOP2019000060A/es unknown
- 2019-03-14 NI NI201900023A patent/NI201900023A/es unknown
- 2019-04-12 ZA ZA2019/02325A patent/ZA201902325B/en unknown
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2021
- 2021-01-28 US US17/161,201 patent/US11472803B2/en active Active
- 2021-01-28 US US17/161,186 patent/US20220089591A1/en not_active Abandoned
- 2021-09-02 HR HRP20211396TT patent/HRP20211396T1/hr unknown
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