MX2015010725A - Formas de metil {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo [3,4-b] piridino-3-il] pirimidino-5-il} metil carbamato. - Google Patents

Formas de metil {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo [3,4-b] piridino-3-il] pirimidino-5-il} metil carbamato.

Info

Publication number
MX2015010725A
MX2015010725A MX2015010725A MX2015010725A MX2015010725A MX 2015010725 A MX2015010725 A MX 2015010725A MX 2015010725 A MX2015010725 A MX 2015010725A MX 2015010725 A MX2015010725 A MX 2015010725A MX 2015010725 A MX2015010725 A MX 2015010725A
Authority
MX
Mexico
Prior art keywords
methyl
pyrimidino
pyridino
fluorobenzyl
pyrazolo
Prior art date
Application number
MX2015010725A
Other languages
English (en)
Inventor
Alfons Grunenberg
Franz-Josef Mais
Birgit Keil
Winfried Joentgen
Original Assignee
Adverio Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50137643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2015010725(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CA2807859A external-priority patent/CA2807859A1/en
Application filed by Adverio Pharma Gmbh filed Critical Adverio Pharma Gmbh
Publication of MX2015010725A publication Critical patent/MX2015010725A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

La presente invención se refiere a las formas del metil {4,6-diamino-2-[1-(2-fluorobencil)-1H-pirazolo [3,4-b]piridino-3-il]pirimidino-5-il}metilcarbamato que comprende su modificación I. modificación II. solvato de mono-DMSO. solvato de sesqui-DMSO y solvato de 1/4-acetato de etilo.
MX2015010725A 2013-02-21 2014-02-18 Formas de metil {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo [3,4-b] piridino-3-il] pirimidino-5-il} metil carbamato. MX2015010725A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2806895 2013-02-21
CA2807859A CA2807859A1 (en) 2013-02-21 2013-02-21 Forms of methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl}methyl carbamate
PCT/EP2014/053096 WO2014128109A1 (en) 2013-02-21 2014-02-18 Forms of methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridino-3-yl]pyrimidino-5-yl}methyl carbamate

Publications (1)

Publication Number Publication Date
MX2015010725A true MX2015010725A (es) 2016-05-31

Family

ID=50137643

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015010725A MX2015010725A (es) 2013-02-21 2014-02-18 Formas de metil {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo [3,4-b] piridino-3-il] pirimidino-5-il} metil carbamato.

Country Status (23)

Country Link
US (5) US20150376184A1 (es)
EP (2) EP2958914B1 (es)
JP (1) JP6386478B2 (es)
KR (1) KR20150119871A (es)
CN (1) CN105102457A (es)
AP (1) AP2015008670A0 (es)
AU (1) AU2014220801A1 (es)
BR (1) BR112015019571A2 (es)
CA (1) CA2901636A1 (es)
CL (1) CL2015002304A1 (es)
CR (1) CR20150422A (es)
CU (1) CU20150092A7 (es)
DO (1) DOP2015000199A (es)
EA (1) EA201500852A1 (es)
HK (1) HK1217488A1 (es)
IL (1) IL240397A0 (es)
MX (1) MX2015010725A (es)
NI (1) NI201500110A (es)
PE (1) PE20151590A1 (es)
PH (1) PH12015501839A1 (es)
SG (1) SG11201506211RA (es)
TN (1) TN2015000361A1 (es)
WO (1) WO2014128109A1 (es)

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CN104434845B (zh) * 2014-11-12 2017-12-05 广东东阳光药业有限公司 一种包含利奥西呱的固体药物制剂
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Also Published As

Publication number Publication date
AP2015008670A0 (en) 2015-08-31
US20220073515A1 (en) 2022-03-10
NI201500110A (es) 2016-02-15
US20170334910A1 (en) 2017-11-23
EP2958914B1 (en) 2020-07-15
US11203593B2 (en) 2021-12-21
PH12015501839A1 (en) 2015-11-09
HK1217488A1 (zh) 2017-01-13
US10662188B2 (en) 2020-05-26
WO2014128109A1 (en) 2014-08-28
AU2014220801A1 (en) 2015-09-10
JP2016509039A (ja) 2016-03-24
US20200239469A1 (en) 2020-07-30
EP2958914A1 (en) 2015-12-30
SG11201506211RA (en) 2015-09-29
PE20151590A1 (es) 2015-11-19
TN2015000361A1 (en) 2017-01-03
BR112015019571A2 (pt) 2017-07-18
JP6386478B2 (ja) 2018-09-05
DOP2015000199A (es) 2015-11-15
KR20150119871A (ko) 2015-10-26
EP3760629A1 (en) 2021-01-06
US20180370970A1 (en) 2018-12-27
CN105102457A (zh) 2015-11-25
CU20150092A7 (es) 2016-03-31
CR20150422A (es) 2015-12-01
US20150376184A1 (en) 2015-12-31
CL2015002304A1 (es) 2016-06-03
IL240397A0 (en) 2015-09-24
CA2901636A1 (en) 2014-08-28
EA201500852A1 (ru) 2016-02-29
US10087183B2 (en) 2018-10-02

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